Motif ID: TFEB.p2

Z-value: 1.259


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB



Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_+_9126742 5.538 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr6_+_87921980 5.032 NM_015021
ZNF292
zinc finger protein 292
chr4_+_128870968 3.907 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr3_-_20202622 3.429 NM_001012409
NM_001012410
NM_001012411
NM_001012412
NM_001012413
NM_138484
SGOL1





shugoshin-like 1 (S. pombe)





chr11_+_120399966 3.092 NM_001130047
NM_152715
TBCEL

tubulin folding cofactor E-like

chr2_+_46779553 3.005 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr19_+_37528340 2.880 NM_001136156
NM_014910
ZNF507

zinc finger protein 507

chr6_+_127629677 2.788 NM_030963
RNF146
ring finger protein 146
chr5_+_41940216 2.422 NM_175921
C5orf51
chromosome 5 open reading frame 51
chr1_-_152459667 2.417 C1orf43
chromosome 1 open reading frame 43
chr11_+_18300689 2.378 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr6_-_84994032 2.321 NM_014895
KIAA1009
KIAA1009
chr1_-_39097904 2.234 NM_022157
RRAGC
Ras-related GTP binding C
chr1_-_152459506 2.204 C1orf43
chromosome 1 open reading frame 43
chr4_+_164484540 2.132 NM_006174
NPY5R
neuropeptide Y receptor Y5
chr7_+_154720547 2.129 INSIG1
insulin induced gene 1
chr20_+_37024383 2.124 NM_001190809
NM_021931
DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr1_+_152459918 2.083 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr3_-_172109119 2.066 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr3_-_172109075 2.048 EIF5A2
eukaryotic translation initiation factor 5A2
chr1_+_148521852 1.995 NM_144697
C1orf51
chromosome 1 open reading frame 51
chr1_-_11788666 1.965 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr5_+_139473873 1.946 NM_005859
PURA
purine-rich element binding protein A
chr8_+_59628281 1.884 NM_001007067
NM_001007068
NM_001007069
NM_001007070
NM_005625
SDCBP




syndecan binding protein (syntenin)




chr12_-_121316907 1.875 VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr14_+_44622916 1.852 NM_017922
PRPF39
PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae)
chr5_+_65476418 1.852 NM_139168
SREK1
splicing regulatory glutamine/lysine-rich protein 1
chr18_+_54958095 1.842 NM_033280
SEC11C
SEC11 homolog C (S. cerevisiae)
chr1_-_152459697 1.837 NM_001098616
NM_015449
NM_138740
C1orf43


chromosome 1 open reading frame 43


chr2_-_55090759 1.834 NM_007008
RTN4
reticulon 4
chr11_+_125586828 1.781 NM_024556
FAM118B
family with sequence similarity 118, member B
chr8_+_26296439 1.756 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr8_+_59628337 1.755 SDCBP
syndecan binding protein (syntenin)
chr6_+_160310118 1.754 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr9_+_116389814 1.724 NM_004888
ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr8_+_59628352 1.699 SDCBP
syndecan binding protein (syntenin)
chr11_-_85457736 1.678 PICALM
phosphatidylinositol binding clathrin assembly protein
chr1_+_11788827 1.641 CLCN6
chloride channel 6
chr5_+_148766632 1.641 LOC728264
hypothetical LOC728264
chr1_-_11788550 1.640 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr11_-_85457753 1.614 NM_001008660
NM_007166
PICALM

phosphatidylinositol binding clathrin assembly protein

chr1_+_11788889 1.590 CLCN6
chloride channel 6
chr8_+_59628372 1.576 SDCBP
syndecan binding protein (syntenin)
chr1_-_201162991 1.572 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr1_+_208178160 1.564 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV



chr12_+_52665196 1.562 NM_017409
HOXC10
homeobox C10
chr18_+_75967902 1.558 NM_014913
ADNP2
ADNP homeobox 2
chr13_-_109236897 1.543 NM_003749
IRS2
insulin receptor substrate 2
chr6_-_33493792 1.540 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr14_-_54025414 1.537 GMFB
glia maturation factor, beta
chr1_+_76312962 1.531 NM_001160011
NM_152996
ST6GALNAC3

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3

chr7_+_4781784 1.512 NM_014855
KIAA0415
KIAA0415
chr11_-_18300246 1.509 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr12_+_132124125 1.499 ZNF84
zinc finger protein 84
chr1_-_201162938 1.496 KLHL12
kelch-like 12 (Drosophila)
chr8_+_104102477 1.482 ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr21_+_37367432 1.479 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr10_-_120504445 1.476 C10orf46
chromosome 10 open reading frame 46
chr6_-_80713589 1.463 NM_022726
ELOVL4
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr3_-_121550767 1.449 NM_001099678
LRRC58
leucine rich repeat containing 58
chr12_+_52653176 1.443 NM_014212
HOXC11
homeobox C11
chr11_+_9642229 1.441 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr6_-_33494042 1.436 NM_001014433
NM_001014837
NM_001014838
NM_001014840
NM_015921
CUTA




cutA divalent cation tolerance homolog (E. coli)




chr4_+_56414565 1.436 NM_001024924
NM_018261
NM_178237
EXOC1


exocyst complex component 1


chr6_-_151754337 1.430 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr11_+_9642226 1.426 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr11_+_101485946 1.422 NM_001130145
NM_001195044
NM_006106
YAP1


Yes-associated protein 1


chr18_+_30875297 1.403 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr10_+_112317401 1.400 NM_005445
SMC3
structural maintenance of chromosomes 3
chr5_+_133734768 1.395 NM_003337
UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr3_+_150191884 1.386 NM_001184720
NM_001184721
NM_004130
GYG1


glycogenin 1


chr10_+_22649977 1.367 NM_005180
BMI1
BMI1 polycomb ring finger oncogene
chr22_-_49413326 1.366 NM_000487
NM_001085425
NM_001085426
NM_001085427
NM_001085428
ARSA




arylsulfatase A




chr5_+_34692124 1.365 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr8_+_71744153 1.360 NM_001011720
XKR9
XK, Kell blood group complex subunit-related family, member 9
chr1_-_26105477 1.357 NM_001145454
NM_005563
STMN1

stathmin 1

chr11_+_9642200 1.342 NM_015055
SWAP70
SWAP switching B-cell complex 70kDa subunit
chr11_-_36267510 1.321 COMMD9
COMM domain containing 9
chr11_-_71491983 1.315 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr11_-_71491916 1.309 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr1_+_66772393 1.302 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr7_+_17304707 1.301 NM_001621
AHR
aryl hydrocarbon receptor
chr12_-_121316997 1.284 NM_022916
VPS33A
vacuolar protein sorting 33 homolog A (S. cerevisiae)
chr13_+_41744255 1.282 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr6_-_33493898 1.269 CUTA
cutA divalent cation tolerance homolog (E. coli)
chr11_+_9642182 1.250 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr9_+_124742932 1.248 NM_012197
RABGAP1
RAB GTPase activating protein 1
chr14_-_19999475 1.247 NM_001100814
NM_144568
TMEM55B

transmembrane protein 55B

chr1_+_109221271 1.245 GPSM2
G-protein signaling modulator 2
chr1_-_152797820 1.243 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr15_-_71712605 1.238 NPTN
neuroplastin
chr1_-_165112157 1.238 NM_053053
TADA1
transcriptional adaptor 1
chr10_+_121642204 1.231 NM_007190
SEC23IP
SEC23 interacting protein
chr5_+_34692239 1.218 RAI14
retinoic acid induced 14
chr1_-_152797707 1.217 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr3_+_160002605 1.208 MFSD1
major facilitator superfamily domain containing 1
chr18_+_12397894 1.204 NM_001142405
NM_006553
SLMO1

slowmo homolog 1 (Drosophila)

chr14_+_61231795 1.202 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr11_-_71491942 1.197 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr9_-_103289154 1.193 NM_032342
C9orf125
chromosome 9 open reading frame 125
chr18_+_42751510 1.193 KATNAL2
katanin p60 subunit A-like 2
chr14_-_19999324 1.193 TMEM55B
transmembrane protein 55B
chr3_+_160002571 1.190 MFSD1
major facilitator superfamily domain containing 1
chr2_+_187266899 1.188 NM_177454
FAM171B
family with sequence similarity 171, member B
chr17_+_5126275 1.178 NM_001083585
NM_004703
RABEP1

rabaptin, RAB GTPase binding effector protein 1

chr12_+_104025675 1.171 KIAA1033
KIAA1033
chr15_-_71712711 1.163 NM_001161363
NM_001161364
NM_012428
NM_017455
NPTN



neuroplastin



chr12_+_104025667 1.161 KIAA1033
KIAA1033
chr2_+_227898163 1.150 MFF
mitochondrial fission factor
chr3_+_150330060 1.146 NM_032383
HPS3
Hermansky-Pudlak syndrome 3
chr12_+_63132106 1.138 NM_013254
TBK1
TANK-binding kinase 1
chr3_+_160002582 1.135 MFSD1
major facilitator superfamily domain containing 1
chr8_-_66863841 1.128 NM_002603
PDE7A
phosphodiesterase 7A
chr1_+_11788793 1.127 NM_001286
NM_021735
NM_021736
NM_021737
CLCN6



chloride channel 6



chr4_-_100069303 1.126 EIF4E
eukaryotic translation initiation factor 4E
chr11_-_47427263 1.126 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr11_-_36267550 1.120 NM_001101653
NM_014186
COMMD9

COMM domain containing 9

chr12_-_40918417 1.114 NM_001190979
NM_001190980
NM_005748
YAF2


YY1 associated factor 2


chr7_+_4781803 1.093 KIAA0415
KIAA0415
chr5_+_110102607 1.088 SLC25A46
solute carrier family 25, member 46
chr18_-_42751305 1.081 NM_004671
NM_173206
PIAS2

protein inhibitor of activated STAT, 2

chr3_+_129927726 1.081 RAB7A
RAB7A, member RAS oncogene family
chr8_-_71743908 1.079 LACTB2
lactamase, beta 2
chr5_+_110102639 1.077 NM_138773
SLC25A46
solute carrier family 25, member 46
chr17_+_3486753 1.071 CTNS
cystinosis, nephropathic
chr3_+_142143329 1.065 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr3_+_114948550 1.064 NM_001690
ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr22_-_37425937 1.061 NM_014876
JOSD1
Josephin domain containing 1
chr8_+_76059262 1.060 NM_031461
CRISPLD1
cysteine-rich secretory protein LCCL domain containing 1
chr3_+_129927723 1.059 RAB7A
RAB7A, member RAS oncogene family
chr5_+_133735004 1.057 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr10_-_112054679 1.056 NM_005871
SMNDC1
survival motor neuron domain containing 1
chr1_+_205293217 1.045 NM_001018053
NM_006212
PFKFB2

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2

chr12_-_47396724 1.044 NM_001240
CCNT1
cyclin T1
chr1_-_165112093 1.041 TADA1
transcriptional adaptor 1
chr8_+_1759502 1.031 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr4_-_164473107 1.025 NM_000909
NPY1R
neuropeptide Y receptor Y1
chr12_+_104025578 1.023 NM_015275
KIAA1033
KIAA1033
chr7_+_154720416 1.015 NM_005542
NM_198336
NM_198337
INSIG1


insulin induced gene 1


chr2_+_46779827 1.014 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr1_-_24024432 1.013 HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr6_+_151688327 1.012 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_152797760 1.011 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr4_-_100069265 0.996 NM_001130678
EIF4E
eukaryotic translation initiation factor 4E
chr4_+_128773529 0.996 NM_015693
INTU
inturned planar cell polarity effector homolog (Drosophila)
chr10_+_22650145 0.992 BMI1
BMI1 polycomb ring finger oncogene
chr1_-_184916044 0.992 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr1_-_152797767 0.992 UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr3_+_129927668 0.992 NM_004637
RAB7A
RAB7A, member RAS oncogene family
chr3_+_129927716 0.989 RAB7A
RAB7A, member RAS oncogene family
chr1_-_33585848 0.987


chr4_-_101034525 0.981 LAMTOR3
late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr3_+_186012670 0.978 VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr5_-_133734616 0.978 CDKL3
cyclin-dependent kinase-like 3
chr8_-_71743973 0.976 NM_016027
LACTB2
lactamase, beta 2
chr11_-_71492019 0.975 NM_017907
LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr3_+_134775946 0.972 NM_001134423
CDV3
CDV3 homolog (mouse)
chr12_-_40918249 0.970 NM_001190977
YAF2
YY1 associated factor 2
chr10_+_70553936 0.968 VPS26A
vacuolar protein sorting 26 homolog A (S. pombe)
chr18_+_75968133 0.966 ADNP2
ADNP homeobox 2
chr6_-_43305156 0.961 NM_006443
NM_199184
C6orf108

chromosome 6 open reading frame 108

chr1_+_159550789 0.960 NM_001035511
NM_001035512
NM_001035513
NM_003001
SDHC



succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa



chr12_+_104025686 0.959


chr3_+_129927714 0.957 RAB7A
RAB7A, member RAS oncogene family
chr11_+_111543304 0.957 NM_031275
TEX12
testis expressed 12
chr3_+_114948591 0.952 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr6_+_64403631 0.941 PHF3
PHD finger protein 3
chr11_+_113815317 0.937 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr14_-_64638974 0.934 NM_002382
NM_145112
NM_145113
NM_145114
NM_145116
NM_197957
MAX





MYC associated factor X





chr14_-_54948290 0.934 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr1_-_94475840 0.932 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr1_-_24024519 0.932 NM_000191
NM_001166059
HMGCL

3-hydroxymethyl-3-methylglutaryl-CoA lyase

chr5_+_34692352 0.931 NM_001145520
RAI14
retinoic acid induced 14
chr16_-_4528739 0.931 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr3_+_160002619 0.929 MFSD1
major facilitator superfamily domain containing 1
chr7_+_92699588 0.924 NM_017667
NM_024553
CCDC132

coiled-coil domain containing 132

chr8_+_133856793 0.922 PHF20L1
PHD finger protein 20-like 1
chr10_-_32257693 0.919 ARHGAP12
Rho GTPase activating protein 12
chr12_-_104025540 0.917 LOC414300
hypothetical LOC414300
chr1_+_40399642 0.913 RLF
rearranged L-myc fusion
chr10_+_124903911 0.907 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr2_-_105312536 0.905 NM_001142621
NM_004257
TGFBRAP1

transforming growth factor, beta receptor associated protein 1

chr5_+_122138677 0.903 SNX2
sorting nexin 2
chr6_+_64403685 0.902 PHF3
PHD finger protein 3
chr5_+_122138661 0.902 SNX2
sorting nexin 2
chr10_-_112054497 0.899 SMNDC1
survival motor neuron domain containing 1
chr1_+_109810743 0.899 SYPL2
synaptophysin-like 2
chr14_-_54025464 0.899 NM_004124
GMFB
glia maturation factor, beta
chr14_-_91642641 0.896 ATXN3
ATXN8
ataxin 3
ataxin 8
chr12_-_63439449 0.893 GNS
glucosamine (N-acetyl)-6-sulfatase
chr11_-_85457469 0.893 PICALM
phosphatidylinositol binding clathrin assembly protein
chr11_+_18300370 0.892 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr7_+_100302885 0.892 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr1_+_40399618 0.890 NM_012421
RLF
rearranged L-myc fusion
chr9_+_116389918 0.889 ATP6V1G1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
chr6_+_151603201 0.886 AKAP12
A kinase (PRKA) anchor protein 12
chr12_+_102982365 0.884 NM_013320
HCFC2
host cell factor C2
chr8_+_104102417 0.873 NM_001695
ATP6V1C1
ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1
chr1_+_246375072 0.873 NM_001004690
OR2M5
olfactory receptor, family 2, subfamily M, member 5
chr18_-_45241014 0.872 NM_017653
DYM
dymeclin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.74 4.60e-05 GO:0033036 macromolecule localization
1.82 7.55e-05 GO:0008104 protein localization
1.90 1.43e-04 GO:0045184 establishment of protein localization
1.91 1.48e-04 GO:0015031 protein transport
7.43 1.82e-04 GO:0015682 ferric iron transport
7.43 1.82e-04 GO:0033572 transferrin transport
4.65 2.35e-03 GO:0006818 hydrogen transport
2.06 3.43e-03 GO:0034613 cellular protein localization
2.05 4.10e-03 GO:0070727 cellular macromolecule localization
5.07 5.17e-03 GO:0007033 vacuole organization
4.47 9.18e-03 GO:0015992 proton transport
2.17 9.36e-03 GO:0006886 intracellular protein transport
3.10 1.30e-02 GO:0008286 insulin receptor signaling pathway
6.08 1.85e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
6.08 1.85e-02 GO:0015991 ATP hydrolysis coupled proton transport
2.25 1.86e-02 GO:0071495 cellular response to endogenous stimulus
1.76 2.17e-02 GO:0046907 intracellular transport
1.35 4.18e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56 4.32e-02 GO:0051641 cellular localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
3.35 8.42e-12 GO:0005773 vacuole
1.17 2.59e-09 GO:0044424 intracellular part
1.16 3.60e-09 GO:0005622 intracellular
1.23 1.07e-08 GO:0043227 membrane-bounded organelle
1.23 1.40e-08 GO:0043231 intracellular membrane-bounded organelle
1.19 6.21e-08 GO:0043226 organelle
3.10 6.42e-08 GO:0000323 lytic vacuole
3.10 6.42e-08 GO:0005764 lysosome
1.19 6.94e-08 GO:0043229 intracellular organelle
1.22 7.05e-07 GO:0005737 cytoplasm
10.14 3.32e-06 GO:0033176 proton-transporting V-type ATPase complex
1.27 1.14e-05 GO:0044444 cytoplasmic part
2.31 1.50e-05 GO:0005768 endosome
3.36 1.85e-05 GO:0044437 vacuolar part
3.38 2.92e-05 GO:0005774 vacuolar membrane
1.27 2.95e-05 GO:0044422 organelle part
1.27 4.49e-05 GO:0044446 intracellular organelle part
3.38 5.27e-05 GO:0005769 early endosome
2.70 7.37e-05 GO:0010008 endosome membrane
2.68 8.90e-05 GO:0044440 endosomal part
4.10 9.76e-05 GO:0042470 melanosome
4.10 9.76e-05 GO:0048770 pigment granule
3.47 3.74e-04 GO:0005770 late endosome
4.43 7.60e-04 GO:0031902 late endosome membrane
1.06 4.72e-03 GO:0044464 cell part
1.06 4.82e-03 GO:0005623 cell
1.72 7.14e-03 GO:0031410 cytoplasmic vesicle
1.40 7.19e-03 GO:0044428 nuclear part
1.53 8.71e-03 GO:0005654 nucleoplasm
1.70 1.01e-02 GO:0031982 vesicle
11.26 1.06e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
1.21 1.11e-02 GO:0005634 nucleus
1.29 1.17e-02 GO:0032991 macromolecular complex
4.71 1.22e-02 GO:0016469 proton-transporting two-sector ATPase complex
1.71 1.56e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.37 1.91e-02 GO:0070013 intracellular organelle lumen
10.14 2.04e-02 GO:0016471 vacuolar proton-transporting V-type ATPase complex
1.36 2.19e-02 GO:0031974 membrane-enclosed lumen
1.36 2.22e-02 GO:0043233 organelle lumen
1.68 2.62e-02 GO:0031988 membrane-bounded vesicle
1.41 2.94e-02 GO:0031981 nuclear lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.79 1.76e-04 GO:0003713 transcription coactivator activity
1.11 2.02e-03 GO:0005488 binding
1.19 2.28e-03 GO:0005515 protein binding
7.88 6.62e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
1.99 3.27e-02 GO:0003712 transcription cofactor activity
1.99 3.46e-02 GO:0000988 protein binding transcription factor activity
1.99 3.46e-02 GO:0000989 transcription factor binding transcription factor activity
5.41 3.65e-02 GO:0019829 cation-transporting ATPase activity