Motif ID: ZEB1.p2

Z-value: 1.694


Transcription factors associated with ZEB1.p2:

Gene SymbolEntrez IDGene Name
ZEB1 6935 zinc finger E-box binding homeobox 1



Activity profile for motif ZEB1.p2.

activity profile for motif ZEB1.p2


Sorted Z-values histogram for motif ZEB1.p2

Sorted Z-values for motif ZEB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZEB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_43447078 3.018 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_43446937 2.822 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447262 2.681 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr22_+_38720881 2.131 NM_138435
FAM83F
family with sequence similarity 83, member F
chr4_+_75529716 1.511 NM_001657
AREG
amphiregulin
chr4_+_75699652 1.261 NM_001657
AREG
amphiregulin
chr21_+_36993302 1.220


chr12_+_131797455 1.052 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr7_+_1536847 1.020 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr2_+_10779191 0.901 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr14_-_105392671 0.890


chr19_+_6415259 0.805 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr16_+_270606 0.802 NM_001176
ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma
chr1_-_16812274 0.781 NM_017940
NBPF1
neuroblastoma breakpoint family, member 1
chrX_+_48915127 0.781 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr7_-_130891861 0.773 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr19_-_51690989 0.726 NM_020709
PNMAL2
PNMA-like 2
chr12_+_6179736 0.722 NM_001769
CD9
CD9 molecule
chr9_-_139060416 0.720 NM_015392
NPDC1
neural proliferation, differentiation and control, 1
chr19_+_590878 0.711 NM_020637
FGF22
fibroblast growth factor 22
chr9_-_139060377 0.711 NPDC1
neural proliferation, differentiation and control, 1
chr16_+_87232501 0.687 NM_013278
IL17C
interleukin 17C
chr5_+_167651063 0.685 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chrX_-_30817329 0.674 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr9_+_132874324 0.650 NM_006059
LAMC3
laminin, gamma 3
chr9_-_139060285 0.650 NPDC1
neural proliferation, differentiation and control, 1
chr3_+_53170254 0.647 NM_006254
NM_212539
PRKCD

protein kinase C, delta

chr19_+_7566698 0.644 NM_001080429
NM_020902
KIAA1543

KIAA1543

chrX_-_13866565 0.642 NM_001001994
GPM6B
glycoprotein M6B
chr9_+_37640996 0.632 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr21_+_36993860 0.596 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr14_+_73775927 0.593 NM_182894
VSX2
visual system homeobox 2
chr17_-_76064842 0.590 NM_002522
NPTX1
neuronal pentraxin I
chr19_-_1083109 0.583 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr9_-_125070675 0.579 NM_001171137
STRBP
spermatid perinuclear RNA binding protein
chr17_-_77634455 0.565 FASN
fatty acid synthase
chr18_+_75724655 0.562 NM_012283
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr9_+_138900760 0.552 NM_021138
TRAF2
TNF receptor-associated factor 2
chr13_+_26896614 0.550 NM_002097
GTF3A
general transcription factor IIIA
chr17_+_71229110 0.549 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr15_-_53822468 0.543 NM_173814
PRTG
protogenin
chr19_-_1518875 0.541 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr17_+_21220260 0.535 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chrX_+_151991474 0.531 NM_001170944
NM_032882
LOC100287428
PNMA6A
paraneoplastic antigen-like protein 6A related gene
paraneoplastic antigen like 6A
chr17_+_71229151 0.525 ITGB4
integrin, beta 4
chr6_-_3172775 0.522 NM_178012
TUBB2B
tubulin, beta 2B
chr18_+_59295123 0.520 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr9_-_92444886 0.519 NM_017594
DIRAS2
DIRAS family, GTP-binding RAS-like 2
chr17_+_71229191 0.514 ITGB4
integrin, beta 4
chr22_+_18081968 0.511 NM_002688
SEPT5
septin 5
chr5_-_1348103 0.509 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr19_-_17793312 0.506 NM_005543
INSL3
insulin-like 3 (Leydig cell)
chr19_-_17217022 0.506 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chrX_+_149280486 0.504 MAMLD1
mastermind-like domain containing 1
chr17_-_77635703 0.502 FASN
fatty acid synthase
chr19_+_51498695 0.498 NM_152794
HIF3A
hypoxia inducible factor 3, alpha subunit
chr19_-_45016587 0.495 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr9_+_125813849 0.491 LHX2
LIM homeobox 2
chr22_-_22422951 0.488 NM_021916
ZNF70
zinc finger protein 70
chr17_-_76811297 0.482 NM_001009811
NM_014984
AZI1

5-azacytidine induced 1

chrX_+_130019896 0.481 NM_144967
ARHGAP36
Rho GTPase activating protein 36
chr10_-_133971136 0.481 NM_173575
STK32C
serine/threonine kinase 32C
chrX_-_17789276 0.478 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr22_-_40408331 0.478 NM_005008
NHP2L1
NHP2 non-histone chromosome protein 2-like 1 (S. cerevisiae)
chr4_-_8211335 0.475 NM_001130083
NM_001130084
NM_001130085
NM_001130086
NM_001130087
NM_001130088
NM_032432
ABLIM2






actin binding LIM protein family, member 2






chr7_-_45927263 0.472 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr11_-_550706 0.470 NM_173573
C11orf35
chromosome 11 open reading frame 35
chr9_-_125070613 0.464 NM_018387
STRBP
spermatid perinuclear RNA binding protein
chr22_+_18124225 0.462 NM_005992
NM_080646
NM_080647
TBX1


T-box 1


chr5_+_665454 0.458 CEP72
centrosomal protein 72kDa
chr17_+_7393098 0.457 NM_172089
NM_003809
TNFSF12-TNFSF13
TNFSF12
TNFSF12-TNFSF13 readthrough
tumor necrosis factor (ligand) superfamily, member 12
chr18_-_45975163 0.456 NM_001080467
MYO5B
myosin VB
chr3_-_198839026 0.453 LOC220729
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene
chrX_+_47305459 0.453 NM_001654
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr19_-_43406621 0.452 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chrX_-_13866451 0.451 GPM6B
glycoprotein M6B
chr22_-_41419800 0.449 A4GALT
alpha 1,4-galactosyltransferase
chrX_+_130985316 0.442 NM_001042452
MST4
serine/threonine protein kinase MST4
chr12_-_116112495 0.442 NM_015002
NM_033624
FBXO21

F-box protein 21

chr11_+_12088639 0.436 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr7_+_45163891 0.436 NM_005856
RAMP3
receptor (G protein-coupled) activity modifying protein 3
chr1_+_204390905 0.434 NM_000707
AVPR1B
arginine vasopressin receptor 1B
chrX_-_152804731 0.432 L1CAM
L1 cell adhesion molecule
chr8_-_143482433 0.432 NM_145003
TSNARE1
t-SNARE domain containing 1
chr2_+_74595073 0.427 NM_016170
TLX2
T-cell leukemia homeobox 2
chr16_+_4415805 0.426 NM_001135110
NM_005147
DNAJA3

DnaJ (Hsp40) homolog, subfamily A, member 3

chr5_+_665404 0.423 NM_018140
CEP72
centrosomal protein 72kDa
chr6_+_47553399 0.420 NM_012120
CD2AP
CD2-associated protein
chr1_+_61980679 0.418 NM_176877
INADL
InaD-like (Drosophila)
chr8_+_145393450 0.416 NM_001008271
NM_001080514
SCXA
SCXB
scleraxis homolog A (mouse)
scleraxis homolog B (mouse)
chrX_+_151557292 0.415 NM_018558
GABRQ
gamma-aminobutyric acid (GABA) receptor, theta
chr12_+_53229625 0.414 PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr2_-_241408296 0.412 NM_004321
KIF1A
kinesin family member 1A
chr17_+_58908152 0.409 NM_000789
ACE
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr7_+_45580704 0.407 ADCY1
adenylate cyclase 1 (brain)
chr21_+_41719847 0.404 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr15_-_100082134 0.403 NM_152334
TARSL2
threonyl-tRNA synthetase-like 2
chr19_+_18584666 0.401 NM_012109
TMEM59L
transmembrane protein 59-like
chr17_+_4434582 0.400 NM_001114974
SMTNL2
smoothelin-like 2
chr19_-_15421761 0.398 NM_021241
WIZ
widely interspaced zinc finger motifs
chr7_+_45580606 0.396 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr16_+_67236730 0.392 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr19_+_40431359 0.389 NM_015925
NM_205834
NM_205835
LSR


lipolysis stimulated lipoprotein receptor


chr22_-_19122047 0.386 SCARF2
scavenger receptor class F, member 2
chr8_-_144882679 0.385 FAM83H
family with sequence similarity 83, member H
chr8_-_144862266 0.385 NM_001162914
LOC100130274
coiled-coil domain containing 121-like
chr1_+_109594163 0.383 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr22_-_17489718 0.383 DGCR2
DiGeorge syndrome critical region gene 2
chr19_+_49972965 0.382 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr17_-_8643163 0.382 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr8_+_1699418 0.382 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr4_-_152155827 0.380 LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr7_+_115637795 0.380 NM_015641
TES
testis derived transcript (3 LIM domains)
chr19_+_1033797 0.379 HMHA1
histocompatibility (minor) HA-1
chr16_+_88280569 0.378 NM_001098533
NM_001160367
NM_052987
NM_052988
CDK10



cyclin-dependent kinase 10



chr9_+_138900795 0.378 TRAF2
TNF receptor-associated factor 2
chr19_+_41039649 0.378 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr11_+_70841864 0.375 NM_018161
NADSYN1
NAD synthetase 1
chr1_+_1971762 0.374 NM_002744
PRKCZ
protein kinase C, zeta
chr20_+_25176698 0.374 NM_002862
PYGB
phosphorylase, glycogen; brain
chr1_-_6218554 0.373 ICMT
isoprenylcysteine carboxyl methyltransferase
chrX_+_48221323 0.372 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr3_+_138965844 0.368 SOX14
SRY (sex determining region Y)-box 14
chr19_+_10392128 0.368 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr7_+_5598979 0.367 NM_003088
FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr16_+_1668257 0.367 NM_144570
HN1L
hematological and neurological expressed 1-like
chrX_-_13866366 0.367


chr19_+_40431618 0.367 LSR
lipolysis stimulated lipoprotein receptor
chr11_+_70841910 0.366 NADSYN1
NAD synthetase 1
chr17_+_26060617 0.363


chrX_-_20044670 0.361 NM_001168467
MAP7D2
MAP7 domain containing 2
chr9_+_134447795 0.360 NM_020064
BARHL1
BarH-like homeobox 1
chr1_-_3556420 0.360 NM_017818
WDR8
WD repeat domain 8
chr1_+_37712716 0.356 ZC3H12A
zinc finger CCCH-type containing 12A
chr20_+_56159388 0.356 NM_178456
C20orf85
chromosome 20 open reading frame 85
chr14_+_64240902 0.355 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr21_+_41610530 0.355 NM_058186
NM_206964
FAM3B

family with sequence similarity 3, member B

chrX_+_68641802 0.355 NM_015686
FAM155B
family with sequence similarity 155, member B
chr12_+_53229443 0.353 NM_000924
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr11_+_63883192 0.350 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr9_-_139183675 0.349


chrX_+_149612488 0.348 NM_003828
MTMR1
myotubularin related protein 1
chr11_+_66381077 0.348 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr8_+_32525269 0.347 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chrX_-_109925941 0.347 NM_001143981
NM_001143982
NM_001143983
CHRDL1


chordin-like 1


chr15_-_81113676 0.346 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr3_-_8668723 0.344 NM_015931
C3orf32
chromosome 3 open reading frame 32
chr14_+_104402626 0.343 NM_001112726
NM_015005
KIAA0284

KIAA0284

chrX_-_67569894 0.342 NM_002547
OPHN1
oligophrenin 1
chr16_-_66007650 0.341 NM_013304
ZDHHC1
zinc finger, DHHC-type containing 1
chr3_-_184316553 0.341 MCCC1
methylcrotonoyl-CoA carboxylase 1 (alpha)
chr3_-_129690056 0.340 NM_001145661
GATA2
GATA binding protein 2
chr19_+_17843753 0.339 NM_000453
SLC5A5
solute carrier family 5 (sodium iodide symporter), member 5
chr1_+_37712767 0.338 ZC3H12A
zinc finger CCCH-type containing 12A
chr17_+_1905104 0.338 NM_006497
HIC1
hypermethylated in cancer 1
chr13_+_113286979 0.337 TFDP1
transcription factor Dp-1
chr12_+_56271259 0.336 PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr8_-_29262240 0.333 NM_057158
DUSP4
dual specificity phosphatase 4
chr19_+_12810258 0.330 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr8_-_143692814 0.330 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr5_-_132976121 0.330 NM_015082
FSTL4
follistatin-like 4
chr12_+_56271181 0.329 NM_001146258
NM_001146259
NM_001146260
NM_024779
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr19_+_4255590 0.329 NM_024333
FSD1
fibronectin type III and SPRY domain containing 1
chr1_+_1062137 0.328 LOC254099
hypothetical protein LOC254099
chr2_+_120820140 0.328 NM_002193
INHBB
inhibin, beta B
chr12_+_120944174 0.328 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr19_+_61846338 0.327 NM_001193628
LOC147670
hypothetical protein LOC147670
chrX_+_152823722 0.327 NM_000054
NM_001146151
AVPR2

arginine vasopressin receptor 2

chr1_-_6218576 0.327 ICMT
isoprenylcysteine carboxyl methyltransferase
chr9_+_139292094 0.327 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr13_-_49597776 0.326 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr19_+_40431122 0.326 LSR
lipolysis stimulated lipoprotein receptor
chr2_-_97641489 0.325 ACTR1B
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr1_+_37712661 0.325 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr16_+_1668284 0.323 HN1L
hematological and neurological expressed 1-like
chr2_-_133144094 0.323 LYPD1
LY6/PLAUR domain containing 1
chr5_+_76150637 0.322 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr2_-_96145614 0.322 NM_000682
ADRA2B
adrenergic, alpha-2B-, receptor
chr1_+_26744893 0.321 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr10_-_71002998 0.320 NM_020999
NEUROG3
neurogenin 3
chr10_-_98935369 0.319 SLIT1
slit homolog 1 (Drosophila)
chr1_+_117950191 0.319 FAM46C
family with sequence similarity 46, member C
chr9_-_138277467 0.317 NM_181701
QSOX2
quiescin Q6 sulfhydryl oxidase 2
chr4_-_2390050 0.317 NM_001172656
NM_001172657
NM_001172658
NM_020972
ZFYVE28



zinc finger, FYVE domain containing 28



chr1_+_117950029 0.316 NM_017709
FAM46C
family with sequence similarity 46, member C
chr6_+_54819527 0.315 NM_001010872
FAM83B
family with sequence similarity 83, member B
chr5_+_31675181 0.315 PDZD2
PDZ domain containing 2
chr4_-_152156314 0.313 NM_006726
LRBA
LPS-responsive vesicle trafficking, beach and anchor containing
chr1_-_11841476 0.312 NM_002521
NPPB
natriuretic peptide B
chr5_-_132976094 0.312 FSTL4
follistatin-like 4
chr19_+_10242763 0.310 ICAM1
intercellular adhesion molecule 1
chr9_+_94987032 0.310 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr22_-_20419975 0.309 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr16_+_88280594 0.308 CDK10
cyclin-dependent kinase 10
chr5_+_76150588 0.308 NM_005242
F2RL1
coagulation factor II (thrombin) receptor-like 1
chrX_+_16714452 0.307 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr19_+_18391423 0.307


chr16_+_1763185 0.305 NM_001010865
EME2
essential meiotic endonuclease 1 homolog 2 (S. pombe)
chr3_+_184898234 0.303 NM_018023
YEATS2
YEATS domain containing 2
chr12_-_53059234 0.303 ZNF385A
zinc finger protein 385A

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.11 6.68e-08 GO:0005737 cytoplasm
1.06 1.99e-05 GO:0005622 intracellular
1.06 3.79e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 2.56e-05 GO:0005515 protein binding