Motif ID: ZFP161.p2

Z-value: 1.314


Transcription factors associated with ZFP161.p2:

Gene SymbolEntrez IDGene Name
ZFP161 7541 zinc finger protein 161 homolog (mouse)



Activity profile for motif ZFP161.p2.

activity profile for motif ZFP161.p2


Sorted Z-values histogram for motif ZFP161.p2

Sorted Z-values for motif ZFP161.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZFP161.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_43846735 1.558 VEGFA
vascular endothelial growth factor A
chr9_+_138726737 1.371 NM_152421
FAM69B
family with sequence similarity 69, member B
chr1_-_59020875 1.348 JUN
jun proto-oncogene
chr11_-_1549719 1.332 NM_004420
DUSP8
dual specificity phosphatase 8
chr20_-_60415729 1.294 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr16_+_87047159 1.029 ZFPM1
zinc finger protein, multitype 1
chr20_-_61933012 0.959 ZBTB46
zinc finger and BTB domain containing 46
chr17_+_76623540 0.937 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr2_+_28469864 0.911 FOSL2
FOS-like antigen 2
chr2_+_28469850 0.898 FOSL2
FOS-like antigen 2
chr2_+_232281470 0.893 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr17_+_76623553 0.859 BAIAP2
BAI1-associated protein 2
chr13_+_112911055 0.835 NM_003589
CUL4A
cullin 4A
chr19_+_1892157 0.835 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr12_+_131577229 0.805 NM_001142641
FBRSL1
fibrosin-like 1
chr13_-_112910945 0.774 NM_001127202
NM_001127203
NM_018386
PCID2


PCI domain containing 2


chr14_-_104706159 0.765 NM_002226
NM_145159
JAG2

jagged 2

chr14_+_104337923 0.735 NM_001137601
ZBTB42
zinc finger and BTB domain containing 42
chr20_+_48241334 0.731 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr10_+_60606352 0.726 NM_032439
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr2_+_56264627 0.718 NM_001080433
CCDC85A
coiled-coil domain containing 85A
chr20_+_48781457 0.695 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr2_+_241586927 0.694 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr16_+_87047418 0.691 NM_153813
ZFPM1
zinc finger protein, multitype 1
chr19_+_1892184 0.690 CSNK1G2
casein kinase 1, gamma 2
chr1_+_226336983 0.682 NM_001024226
NM_001658
ARF1

ADP-ribosylation factor 1

chr3_+_61522310 0.680 PTPRG
protein tyrosine phosphatase, receptor type, G
chr20_+_17155617 0.671 NM_002594
PCSK2
proprotein convertase subtilisin/kexin type 2
chr3_+_61522219 0.671 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr2_+_10969513 0.651 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr11_+_66381077 0.650 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr2_+_232281491 0.649 PTMA
prothymosin, alpha
chr5_+_170747312 0.646 NM_001037738
NM_002520
NM_199185
NPM1


nucleophosmin (nucleolar phosphoprotein B23, numatrin)


chr18_+_9904249 0.644 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr2_-_47650973 0.639 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr6_+_37245860 0.633 NM_002648
PIM1
pim-1 oncogene
chrX_+_41078353 0.633 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr20_+_56897631 0.632 GNAS
GNAS complex locus
chr5_+_170747543 0.628 NPM1
nucleophosmin (nucleolar phosphoprotein B23, numatrin)
chr17_+_53515725 0.623 NM_080677
DYNLL2
dynein, light chain, LC8-type 2
chr14_+_104338423 0.623 ZBTB42
zinc finger and BTB domain containing 42
chr9_+_139255559 0.619 TUBB2C
tubulin, beta 2C
chr20_+_17155669 0.614 PCSK2
proprotein convertase subtilisin/kexin type 2
chr15_+_29406335 0.612 NM_015995
KLF13
Kruppel-like factor 13
chr20_+_56899904 0.603 GNAS
GNAS complex locus
chr14_+_23590939 0.603 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr20_+_56899867 0.603 GNAS
GNAS complex locus
chr2_+_171280944 0.600 SP5
Sp5 transcription factor
chr5_-_88214720 0.600 MEF2C
myocyte enhancer factor 2C
chr11_-_33847507 0.598 LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_1358664 0.596 DAZAP1
DAZ associated protein 1
chr19_+_10625987 0.595 ILF3
interleukin enhancer binding factor 3, 90kDa
chr16_+_53915971 0.591 NM_024335
IRX6
iroquois homeobox 6
chr20_+_56897549 0.591 GNAS
GNAS complex locus
chrX_+_41078787 0.587 DDX3X
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked
chr8_+_142471290 0.585


chr20_+_56900116 0.580 NM_001077488
GNAS
GNAS complex locus
chr20_+_20296744 0.575 NM_002196
INSM1
insulinoma-associated 1
chr7_+_45580704 0.570 ADCY1
adenylate cyclase 1 (brain)
chr17_-_77411607 0.569 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr18_+_9904202 0.568 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr16_+_84202515 0.568 NM_001134473
KIAA0182
KIAA0182
chr9_+_139255519 0.566 NM_006088
TUBB2C
tubulin, beta 2C
chr17_+_71892271 0.565 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr16_+_1299693 0.565 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr19_+_1358531 0.546 NM_018959
NM_170711
DAZAP1

DAZ associated protein 1

chr10_-_131652007 0.545 NM_001005463
EBF3
early B-cell factor 3
chr5_+_154115046 0.541 LARP1
La ribonucleoprotein domain family, member 1
chr7_+_39956128 0.541 CDK13
cyclin-dependent kinase 13
chr14_+_22411200 0.535 LRP10
low density lipoprotein receptor-related protein 10
chr16_+_84204424 0.532 NM_014615
KIAA0182
KIAA0182
chr19_+_748452 0.532 PTBP1
polypyrimidine tract binding protein 1
chr20_+_1254033 0.529 LOC100507495
hypothetical LOC100507495
chr16_+_1299654 0.522 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr19_-_11452439 0.522 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr2_+_17923404 0.521 NM_002252
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr10_-_60606195 0.515


chr19_+_1358750 0.511 DAZAP1
DAZ associated protein 1
chr4_-_2906361 0.506 NM_001146069
MFSD10
major facilitator superfamily domain containing 10
chr2_+_54536780 0.505 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_+_69939806 0.503 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_77411695 0.503 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr20_+_44091219 0.503 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr16_+_1299637 0.499 NM_003345
NM_194259
UBE2I

ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)

chr14_+_91859289 0.499 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_+_45580606 0.494 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr5_+_154115222 0.492 LARP1
La ribonucleoprotein domain family, member 1
chr10_+_80672842 0.490 ZMIZ1
zinc finger, MIZ-type containing 1
chr19_+_1358604 0.490 DAZAP1
DAZ associated protein 1
chr16_-_695719 0.487 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr20_+_34523231 0.486 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr20_+_34523555 0.484 NM_183006
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr20_+_44091265 0.482 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr2_-_86418143 0.480 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr5_-_88215034 0.480 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr19_+_10626106 0.476 ILF3
interleukin enhancer binding factor 3, 90kDa
chr2_+_120820140 0.467 NM_002193
INHBB
inhibin, beta B
chr20_-_538909 0.466 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr8_+_128817494 0.466 NM_002467
MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chr22_+_20101661 0.464 NM_015094
HIC2
hypermethylated in cancer 2
chr11_+_696103 0.460 NM_022772
EPS8L2
EPS8-like 2
chr11_+_18372689 0.459 LDHA
lactate dehydrogenase A
chr20_+_60151868 0.459 NM_198935
SS18L1
synovial sarcoma translocation gene on chromosome 18-like 1
chr20_+_5055393 0.458 NM_003818
CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr20_+_5934560 0.455 NM_019095
CRLS1
cardiolipin synthase 1
chr20_+_5934964 0.455 CRLS1
cardiolipin synthase 1
chr6_+_64340408 0.453 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr4_+_2031036 0.451 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr7_-_44331544 0.448 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr7_+_1239078 0.448 NM_001080461
UNCX
UNC homeobox
chr4_-_2906335 0.446 MFSD10
major facilitator superfamily domain containing 10
chr20_+_5055653 0.446 CDS2
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
chr1_-_1233109 0.444 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr14_+_64240996 0.440 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr11_+_18372493 0.437 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr14_-_104705753 0.433 JAG2
jagged 2
chr9_+_126060063 0.433 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr14_+_41146513 0.430 NM_152447
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr9_+_136358145 0.426 RXRA
retinoid X receptor, alpha
chr20_+_41519947 0.425 SRSF6
serine/arginine-rich splicing factor 6
chr20_+_254205 0.424 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr20_-_60151835 0.424 NM_002792
PSMA7
proteasome (prosome, macropain) subunit, alpha type, 7
chr10_+_105027431 0.423 INA
internexin neuronal intermediate filament protein, alpha
chr11_+_18372682 0.422 LDHA
lactate dehydrogenase A
chrX_+_41077594 0.421 NM_001193416
NM_001193417
NM_001356
DDX3X


DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked


chr17_-_76064842 0.418 NM_002522
NPTX1
neuronal pentraxin I
chr11_+_66381451 0.418 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr14_+_104226769 0.418 NM_001031714
NM_022489
NM_032714
INF2


inverted formin, FH2 and WH2 domain containing


chr16_+_1143241 0.418 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr20_+_56899643 0.417 NM_001077489
NM_000516
NM_080426
GNAS


GNAS complex locus


chr11_+_18372687 0.417 LDHA
lactate dehydrogenase A
chr2_-_236740710 0.416


chr11_+_64946820 0.416 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr11_+_18372708 0.416 LDHA
lactate dehydrogenase A
chr4_+_158361185 0.415 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr20_+_60898249 0.414 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr11_+_712282 0.411 EPS8L2
EPS8-like 2
chr2_+_104837004 0.411


chr17_+_34279781 0.411 LASP1
LIM and SH3 protein 1
chr7_-_50828159 0.411 GRB10
growth factor receptor-bound protein 10
chrX_+_146801142 0.410 NM_001185075
NM_001185076
NM_001185081
NM_001185082
NM_002024
FMR1




fragile X mental retardation 1




chr17_+_4434582 0.409 NM_001114974
SMTNL2
smoothelin-like 2
chr4_-_2906341 0.409 MFSD10
major facilitator superfamily domain containing 10
chr16_+_971808 0.409 NM_014587
SOX8
SRY (sex determining region Y)-box 8
chr20_+_17155680 0.407 PCSK2
proprotein convertase subtilisin/kexin type 2
chr20_+_57309042 0.405 EDN3
endothelin 3
chr1_+_1971762 0.403 NM_002744
PRKCZ
protein kinase C, zeta
chr9_+_139255563 0.400 TUBB2C
tubulin, beta 2C
chr18_+_9904032 0.398 VAPA
VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr16_+_972064 0.398 SOX8
SRY (sex determining region Y)-box 8
chr4_+_2906403 0.396 C4orf10
chromosome 4 open reading frame 10
chr20_+_11819364 0.393 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr11_-_33847834 0.393 LMO2
LIM domain only 2 (rhombotin-like 1)
chr19_+_876984 0.392 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr4_-_2906256 0.387 MFSD10
major facilitator superfamily domain containing 10
chr22_+_38183262 0.387 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_-_77411707 0.384 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_41327449 0.384 NM_001123066
NM_001123067
NM_005910
NM_016834
NM_016835
NM_016841
MAPT





microtubule-associated protein tau





chr13_+_112911826 0.383 CUL4A
cullin 4A
chr16_+_550394 0.381 NM_145270
C16orf11
chromosome 16 open reading frame 11
chr6_-_16869579 0.381 NM_000332
NM_001128164
ATXN1

ataxin 1

chr10_+_93548261 0.381 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr17_+_77478858 0.380 LOC92659
hypothetical LOC92659
chr14_-_104515738 0.379 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr9_+_126059603 0.378 NM_001166167
NM_001145001
NM_014397
NEK6


NIMA (never in mitosis gene a)-related kinase 6


chr9_+_126060108 0.378 NEK6
NIMA (never in mitosis gene a)-related kinase 6
chr2_+_109729176 0.378 NM_023016
ANKRD57
ankyrin repeat domain 57
chr11_+_566482 0.377 NM_020901
PHRF1
PHD and ring finger domains 1
chr10_+_93548048 0.376 TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr1_-_1274618 0.376 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr17_-_77411733 0.375 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_71229191 0.373 ITGB4
integrin, beta 4
chr6_+_12120709 0.373 NM_002114
HIVEP1
human immunodeficiency virus type I enhancer binding protein 1
chr11_+_627268 0.372 NM_000797
DRD4
dopamine receptor D4
chr10_+_93548119 0.371 NM_025235
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr16_+_25610847 0.371 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr2_+_236067687 0.369 AGAP1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr20_+_8997791 0.368 PLCB4
phospholipase C, beta 4
chr18_+_9903954 0.367 NM_003574
NM_194434
VAPA

VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa

chr16_+_88517187 0.366 NM_006086
TUBB3
tubulin, beta 3
chr3_-_181237210 0.366 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr1_+_1233834 0.365 NM_153339
PUSL1
pseudouridylate synthase-like 1
chr20_+_35407872 0.364 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr9_+_136358134 0.363 NM_002957
RXRA
retinoid X receptor, alpha
chr1_+_153366559 0.363 EFNA1
ephrin-A1
chr8_+_120289735 0.363 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr17_-_77411803 0.362 NM_000918
P4HB
prolyl 4-hydroxylase, beta polypeptide
chrX_+_146801236 0.362 FMR1
fragile X mental retardation 1
chr17_-_77411659 0.360 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr2_+_239000395 0.358 ASB1
ankyrin repeat and SOCS box containing 1
chr17_+_41327808 0.357 MAPT
microtubule-associated protein tau
chr20_+_61374581 0.357 ARFGAP1
ADP-ribosylation factor GTPase activating protein 1
chr4_-_5945596 0.355 NM_001014809
CRMP1
collapsin response mediator protein 1
chr2_+_239000306 0.355 NM_001040445
ASB1
ankyrin repeat and SOCS box containing 1
chr2_+_85619802 0.354 MAT2A
methionine adenosyltransferase II, alpha
chr5_+_179058598 0.354 CANX
calnexin
chr19_+_10625896 0.354 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr16_+_56616970 0.354 MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr19_+_45799060 0.353 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr14_-_22904681 0.353 NM_005864
NM_032459
EFS

embryonal Fyn-associated substrate


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.38 1.29e-19 GO:0007275 multicellular organismal development
1.13 1.62e-19 GO:0009987 cellular process
1.34 7.24e-18 GO:0032502 developmental process
1.60 9.02e-18 GO:0007399 nervous system development
1.20 3.11e-15 GO:0050794 regulation of cellular process
1.37 1.39e-14 GO:0048731 system development
1.34 5.46e-14 GO:0048856 anatomical structure development
1.44 1.09e-13 GO:0030154 cell differentiation
1.43 1.97e-13 GO:0048869 cellular developmental process
1.17 5.30e-13 GO:0065007 biological regulation
1.68 5.78e-13 GO:0022008 neurogenesis
1.18 7.30e-13 GO:0050789 regulation of biological process
1.68 2.17e-12 GO:0048699 generation of neurons
1.39 2.58e-11 GO:0048523 negative regulation of cellular process
1.19 5.07e-11 GO:0044237 cellular metabolic process
1.36 2.44e-10 GO:0048519 negative regulation of biological process
1.57 1.25e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.59 1.58e-09 GO:0048468 cell development
1.23 3.26e-09 GO:0044260 cellular macromolecule metabolic process
1.67 3.42e-09 GO:0030182 neuron differentiation
1.44 5.81e-09 GO:0009653 anatomical structure morphogenesis
1.41 8.27e-09 GO:0023051 regulation of signaling
1.78 1.09e-08 GO:0007417 central nervous system development
1.64 5.17e-08 GO:0045595 regulation of cell differentiation
1.54 7.31e-08 GO:0050793 regulation of developmental process
1.24 1.22e-07 GO:0023052 signaling
1.15 1.71e-07 GO:0008152 metabolic process
1.30 2.39e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.35 2.86e-07 GO:0048513 organ development
1.24 3.51e-07 GO:0080090 regulation of primary metabolic process
1.62 4.40e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.40 5.68e-07 GO:0009966 regulation of signal transduction
1.60 5.89e-07 GO:0009790 embryo development
1.59 9.65e-07 GO:0009890 negative regulation of biosynthetic process
1.60 1.14e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.24 1.20e-06 GO:0060255 regulation of macromolecule metabolic process
1.67 1.39e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.29 1.42e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.23 1.73e-06 GO:0031323 regulation of cellular metabolic process
1.29 1.77e-06 GO:0048522 positive regulation of cellular process
1.15 1.83e-06 GO:0044238 primary metabolic process
1.70 1.84e-06 GO:0031175 neuron projection development
1.28 2.50e-06 GO:0010468 regulation of gene expression
1.65 3.05e-06 GO:0051253 negative regulation of RNA metabolic process
1.61 3.86e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 3.94e-06 GO:0000904 cell morphogenesis involved in differentiation
1.60 4.73e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.26 5.50e-06 GO:0048518 positive regulation of biological process
1.76 5.52e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.27 5.81e-06 GO:0071842 cellular component organization at cellular level
1.26 6.02e-06 GO:0009889 regulation of biosynthetic process
1.58 6.30e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.79 6.88e-06 GO:0007420 brain development
1.62 8.44e-06 GO:0048666 neuron development
1.26 8.62e-06 GO:0031326 regulation of cellular biosynthetic process
1.59 9.76e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.77 1.16e-05 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.69 1.37e-05 GO:0048812 neuron projection morphogenesis
1.25 1.57e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.27 1.58e-05 GO:0009058 biosynthetic process
1.72 1.60e-05 GO:0009968 negative regulation of signal transduction
1.71 1.84e-05 GO:0007409 axonogenesis
1.20 1.93e-05 GO:0019222 regulation of metabolic process
1.69 2.04e-05 GO:0023057 negative regulation of signaling
1.17 2.23e-05 GO:0043170 macromolecule metabolic process
1.25 2.35e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 2.35e-05 GO:0044249 cellular biosynthetic process
1.68 2.38e-05 GO:0010648 negative regulation of cell communication
1.51 2.87e-05 GO:2000026 regulation of multicellular organismal development
1.54 2.92e-05 GO:0010628 positive regulation of gene expression
1.31 3.57e-05 GO:0006464 protein modification process
1.78 3.68e-05 GO:0045597 positive regulation of cell differentiation
1.22 3.82e-05 GO:0007165 signal transduction
1.58 3.83e-05 GO:0000902 cell morphogenesis
1.22 3.85e-05 GO:0016043 cellular component organization
1.68 3.86e-05 GO:0032583 regulation of gene-specific transcription
1.68 3.86e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.46 4.10e-05 GO:0031324 negative regulation of cellular metabolic process
1.73 4.41e-05 GO:0009792 embryo development ending in birth or egg hatching
1.62 4.76e-05 GO:0032990 cell part morphogenesis
1.92 5.61e-05 GO:0007507 heart development
1.55 6.15e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.79 7.15e-05 GO:0060284 regulation of cell development
1.56 8.97e-05 GO:0009887 organ morphogenesis
1.61 9.96e-05 GO:0048858 cell projection morphogenesis
1.72 9.97e-05 GO:0043009 chordate embryonic development
1.49 1.07e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.60 1.07e-04 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.18 1.12e-04 GO:0051716 cellular response to stimulus
1.45 1.13e-04 GO:0006351 transcription, DNA-dependent
1.55 1.15e-04 GO:0010629 negative regulation of gene expression
1.27 1.27e-04 GO:0006355 regulation of transcription, DNA-dependent
1.62 1.36e-04 GO:0072358 cardiovascular system development
1.62 1.36e-04 GO:0072359 circulatory system development
1.31 1.43e-04 GO:0034645 cellular macromolecule biosynthetic process
1.20 1.60e-04 GO:0071840 cellular component organization or biogenesis
1.26 1.78e-04 GO:0051252 regulation of RNA metabolic process
1.29 1.95e-04 GO:0043412 macromolecule modification
1.42 2.03e-04 GO:0009892 negative regulation of metabolic process
1.52 2.06e-04 GO:0030030 cell projection organization
1.36 2.45e-04 GO:0051239 regulation of multicellular organismal process
1.51 2.46e-04 GO:0051254 positive regulation of RNA metabolic process
1.53 2.52e-04 GO:0032989 cellular component morphogenesis
1.23 3.24e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.46 3.42e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
1.30 3.47e-04 GO:0009059 macromolecule biosynthetic process
1.59 3.48e-04 GO:0048585 negative regulation of response to stimulus
1.15 3.66e-04 GO:0032501 multicellular organismal process
1.45 3.78e-04 GO:0051128 regulation of cellular component organization
1.35 5.35e-04 GO:0051641 cellular localization
1.59 5.51e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.61 6.03e-04 GO:0051094 positive regulation of developmental process
1.24 6.64e-04 GO:0044267 cellular protein metabolic process
1.43 7.26e-04 GO:0040011 locomotion
1.41 7.56e-04 GO:0010605 negative regulation of macromolecule metabolic process
1.20 9.77e-04 GO:0034641 cellular nitrogen compound metabolic process
1.38 1.05e-03 GO:0010646 regulation of cell communication
1.69 1.26e-03 GO:0007411 axon guidance
1.38 1.38e-03 GO:0032268 regulation of cellular protein metabolic process
1.72 1.44e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.35 1.73e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.39 1.83e-03 GO:0032774 RNA biosynthetic process
1.44 1.88e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.35 2.50e-03 GO:0051649 establishment of localization in cell
1.19 3.42e-03 GO:0006807 nitrogen compound metabolic process
1.18 3.55e-03 GO:0051179 localization
2.21 3.79e-03 GO:0010720 positive regulation of cell development
1.26 3.85e-03 GO:0048583 regulation of response to stimulus
1.21 4.51e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.76 5.54e-03 GO:0050767 regulation of neurogenesis
2.22 6.34e-03 GO:0003007 heart morphogenesis
1.70 7.45e-03 GO:0051960 regulation of nervous system development
1.33 1.16e-02 GO:0051246 regulation of protein metabolic process
1.25 1.17e-02 GO:0007166 cell surface receptor linked signaling pathway
1.30 1.22e-02 GO:0035556 intracellular signal transduction
2.03 1.33e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.01 1.68e-02 GO:0022604 regulation of cell morphogenesis
1.60 1.73e-02 GO:0007389 pattern specification process
1.22 2.01e-02 GO:0065008 regulation of biological quality
1.37 2.32e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.30 2.35e-02 GO:0009893 positive regulation of metabolic process
1.89 2.39e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
2.50 2.70e-02 GO:0017015 regulation of transforming growth factor beta receptor signaling pathway
1.36 2.88e-02 GO:0009891 positive regulation of biosynthetic process
1.76 2.92e-02 GO:0001701 in utero embryonic development
1.65 2.97e-02 GO:0035295 tube development
1.30 3.55e-02 GO:0031325 positive regulation of cellular metabolic process
1.34 3.73e-02 GO:0042127 regulation of cell proliferation
1.33 4.03e-02 GO:0006793 phosphorus metabolic process
1.33 4.03e-02 GO:0006796 phosphate metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 1.09e-12 GO:0044424 intracellular part
1.10 7.11e-12 GO:0005622 intracellular
1.14 2.04e-11 GO:0043227 membrane-bounded organelle
1.14 2.39e-11 GO:0043231 intracellular membrane-bounded organelle
1.14 9.35e-11 GO:0005737 cytoplasm
1.19 1.70e-09 GO:0005634 nucleus
1.33 1.11e-08 GO:0044428 nuclear part
1.35 3.15e-08 GO:0031981 nuclear lumen
1.10 5.97e-08 GO:0043226 organelle
1.10 8.67e-08 GO:0043229 intracellular organelle
1.41 9.90e-08 GO:0005654 nucleoplasm
1.28 6.25e-07 GO:0031974 membrane-enclosed lumen
1.28 1.08e-06 GO:0043233 organelle lumen
1.28 1.67e-06 GO:0070013 intracellular organelle lumen
1.13 4.78e-05 GO:0044444 cytoplasmic part
1.26 4.93e-05 GO:0005829 cytosol
1.14 5.61e-05 GO:0044446 intracellular organelle part
1.14 1.39e-04 GO:0044422 organelle part
1.43 4.42e-04 GO:0044451 nucleoplasm part
1.58 7.08e-04 GO:0045202 synapse
1.26 2.37e-03 GO:0012505 endomembrane system
1.52 5.08e-03 GO:0043005 neuron projection

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.19 4.23e-15 GO:0005515 protein binding
1.09 6.09e-11 GO:0005488 binding
1.63 7.94e-09 GO:0043565 sequence-specific DNA binding
1.48 8.14e-08 GO:0030528 transcription regulator activity
1.45 2.21e-06 GO:0001071 nucleic acid binding transcription factor activity
1.45 2.21e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.75 5.05e-05 GO:0016564 transcription repressor activity
1.93 9.84e-05 GO:0010843 promoter binding
1.88 2.10e-04 GO:0000975 regulatory region DNA binding
1.88 2.10e-04 GO:0001067 regulatory region nucleic acid binding
1.88 2.10e-04 GO:0044212 transcription regulatory region DNA binding
1.67 5.02e-04 GO:0016563 transcription activator activity
2.31 2.45e-03 GO:0019199 transmembrane receptor protein kinase activity
1.25 2.82e-03 GO:0016740 transferase activity
1.53 2.91e-03 GO:0019904 protein domain specific binding
1.63 5.18e-03 GO:0008134 transcription factor binding
1.16 9.28e-03 GO:0003676 nucleic acid binding
1.20 1.08e-02 GO:0000166 nucleotide binding
1.40 2.09e-02 GO:0004672 protein kinase activity
1.35 2.77e-02 GO:0019899 enzyme binding
1.83 2.87e-02 GO:0008022 protein C-terminus binding
1.34 2.94e-02 GO:0016301 kinase activity
2.30 3.56e-02 GO:0004714 transmembrane receptor protein tyrosine kinase activity