Motif ID: ATF2.p2

Z-value: 0.914


Transcription factors associated with ATF2.p2:

Gene SymbolEntrez IDGene Name
ATF2 1386 activating transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ATF2chr2_-_1757410960.467.2e-02Click!


Activity profile for motif ATF2.p2.

activity profile for motif ATF2.p2


Sorted Z-values histogram for motif ATF2.p2

Sorted Z-values for motif ATF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_43319199 1.744 NM_032538
TTBK1
tau tubulin kinase 1
chr7_-_129379947 1.383 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)

chr6_+_26312758 1.093 NM_003545
HIST1H4E
histone cluster 1, H4e
chr10_+_35524060 1.050 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr7_+_116447499 1.043 ST7
suppression of tumorigenicity 7
chr6_+_136214495 0.824 NM_018945
PDE7B
phosphodiesterase 7B
chr1_+_26368969 0.762 NM_015871
ZNF593
zinc finger protein 593
chr9_+_110664366 0.750 NM_006687
ACTL7A
actin-like 7A
chr7_+_142723340 0.749 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr7_-_100595552 0.741 NM_003378
VGF
VGF nerve growth factor inducible
chr1_+_148089251 0.693 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr9_+_126460511 0.675


chr18_+_30875297 0.672 NM_014268
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr16_-_78192111 0.648 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr1_+_51855343 0.606 OSBPL9
oxysterol binding protein-like 9
chr1_+_6562681 0.589 ZBTB48
zinc finger and BTB domain containing 48
chr11_-_8849485 0.589 ST5
suppression of tumorigenicity 5
chr4_-_153820535 0.573 NM_152680
TMEM154
transmembrane protein 154
chr5_-_172130766 0.565 NM_004417
DUSP1
dual specificity phosphatase 1
chr4_-_56948345 0.565 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr16_-_3008162 0.555 NM_021195
CLDN6
claudin 6
chr1_+_25629968 0.547 NM_018202
TMEM57
transmembrane protein 57
chr1_+_29435534 0.544 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr11_-_2149591 0.544 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr1_+_210275752 0.543 DTL
denticleless homolog (Drosophila)
chr5_-_14924555 0.543 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr9_-_122679283 0.533 PHF19
PHD finger protein 19
chr11_+_61204392 0.524 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr2_+_10969513 0.522 NM_002236
KCNF1
potassium voltage-gated channel, subfamily F, member 1
chr21_-_34820916 0.504 NM_203418
RCAN1
regulator of calcineurin 1
chr1_+_210275735 0.504 DTL
denticleless homolog (Drosophila)
chr9_-_122679387 0.500 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr9_-_72218098 0.500 KLF9
Kruppel-like factor 9
chr6_+_31016755 0.497 NM_080870
DPCR1
diffuse panbronchiolitis critical region 1
chr12_-_31368347 0.497 FAM60A
family with sequence similarity 60, member A
chr1_+_11171967 0.484 NM_021146
ANGPTL7
angiopoietin-like 7
chr9_+_132990760 0.471 NM_005085
NUP214
nucleoporin 214kDa
chr7_-_31347032 0.468 NM_022728
NEUROD6
neurogenic differentiation 6
chr1_-_114925734 0.451 NM_005872
BCAS2
breast carcinoma amplified sequence 2
chr4_+_170817787 0.443 CLCN3
chloride channel 3
chr17_+_31562577 0.439 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr6_-_3102690 0.436 NM_001069
TUBB2A
tubulin, beta 2A
chr19_+_40795456 0.432 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr8_-_95343716 0.431 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr8_-_142446546 0.423 NM_005293
GPR20
G protein-coupled receptor 20
chr7_+_128099581 0.421 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr6_-_30136734 0.420 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)
chr22_+_18499354 0.419 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr1_+_116727514 0.417 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr1_+_6562634 0.408 NM_005341
ZBTB48
zinc finger and BTB domain containing 48
chrX_+_101910713 0.403 LOC100287765
hypothetical LOC100287765
chr10_+_35524835 0.402 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr11_-_33752468 0.397 NM_012175
NM_033406
FBXO3

F-box protein 3

chr4_+_3341521 0.395 NM_198227
RGS12
regulator of G-protein signaling 12
chr8_-_42184350 0.392 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr8_-_42184194 0.389 PLAT
plasminogen activator, tissue
chr11_+_7574992 0.385 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr12_+_55201854 0.381 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr8_-_95343696 0.381 GEM
GTP binding protein overexpressed in skeletal muscle
chr16_-_71639670 0.380 NM_006885
ZFHX3
zinc finger homeobox 3
chr6_+_167445284 0.370 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr6_-_91063301 0.369 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr1_+_17404206 0.365 NM_013358
PADI1
peptidyl arginine deiminase, type I
chr7_-_41709191 0.362 NM_002192
INHBA
inhibin, beta A
chr4_-_187884721 0.359


chr18_+_22060383 0.356 NM_005640
TAF4B
TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr4_+_120276386 0.352 NM_016599
MYOZ2
myozenin 2
chr6_-_31740466 0.352 GPANK1
G patch domain and ankyrin repeats 1
chr1_-_203657803 0.352 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr6_-_15356865 0.351


chr5_-_158690047 0.351 NM_002187
IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
chr22_+_23333610 0.351 NM_001032365
GGT1
gamma-glutamyltransferase 1
chr13_+_51275921 0.349


chr2_-_43676603 0.348 NM_001083953
NM_022065
THADA

thyroid adenoma associated

chr17_-_70901303 0.346 GRB2
growth factor receptor-bound protein 2
chr20_+_5839973 0.344 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr7_-_44992729 0.343 C7orf40
chromosome 7 open reading frame 40
chr5_+_71538456 0.343 MAP1B
microtubule-associated protein 1B
chr6_-_91063181 0.342 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr6_-_3172775 0.341 NM_178012
TUBB2B
tubulin, beta 2B
chr12_+_110328126 0.341 NM_005475
SH2B3
SH2B adaptor protein 3
chr5_-_158567411 0.340 NM_144726
RNF145
ring finger protein 145
chr4_-_140696740 0.337 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr21_-_43671355 0.333 NM_173354
SIK1
salt-inducible kinase 1
chr9_+_70046658 0.333 NM_201453
CBWD5
CBWD3
CBWD1
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 1
COBW domain containing 6
chr19_+_50663089 0.333 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr16_-_54466709 0.332 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr5_-_95323353 0.331 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr12_-_7547552 0.331 NM_004244
NM_203416
CD163

CD163 molecule

chr1_+_114273518 0.329 NM_152696
NM_198268
HIPK1

homeodomain interacting protein kinase 1

chr20_+_31613800 0.327 NM_001039709
NM_005093
CBFA2T2

core-binding factor, runt domain, alpha subunit 2; translocated to, 2

chr3_-_188946168 0.326 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr9_-_110658030 0.324 NM_006686
ACTL7B
actin-like 7B
chr14_-_49399317 0.322 RN7SL2
RNA, 7SL, cytoplasmic 2
chr6_+_39868116 0.316


chr9_+_131291144 0.314


chr11_+_9552809 0.312 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr1_-_109651140 0.312 NM_001010985
MYBPHL
myosin binding protein H-like
chr3_-_158360576 0.311 CCNL1
cyclin L1
chr1_-_148080888 0.310 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr1_+_207944807 0.308 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr1_+_210848726 0.306 ATF3
activating transcription factor 3
chr19_+_1221925 0.304 CIRBP
cold inducible RNA binding protein
chr6_+_30137014 0.303 NM_014596
NM_170783
ZNRD1

zinc ribbon domain containing 1

chr17_+_39213328 0.303 NM_001136483
C17orf105
chromosome 17 open reading frame 105
chr1_-_75849350 0.303 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr1_-_31883051 0.302 PEF1
penta-EF-hand domain containing 1
chr9_+_131291224 0.296 LOC100506190
hypothetical LOC100506190
chr7_-_140270749 0.295 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr1_-_172103745 0.294 GAS5
growth arrest-specific 5 (non-protein coding)
chr9_+_132990834 0.294 NUP214
nucleoporin 214kDa
chr7_+_151284396 0.294 NM_145292
GALNTL5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 5
chr17_+_39741306 0.294 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr1_+_66570363 0.292 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_-_187309442 0.291 NM_004454
ETV5
ets variant 5
chr1_+_210848763 0.289 ATF3
activating transcription factor 3
chr11_-_10487212 0.284 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr15_-_81037554 0.283 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr2_-_224175293 0.281 SCG2
secretogranin II
chr1_+_210275541 0.280 NM_016448
DTL
denticleless homolog (Drosophila)
chr3_-_155524898 0.278 NM_001114397
NM_020865
DHX36

DEAH (Asp-Glu-Ala-His) box polypeptide 36

chr1_+_203106600 0.277 NFASC
neurofascin
chr4_+_129021514 0.276 NM_001190801
PLK4
polo-like kinase 4
chr4_-_170770111 0.275 NM_012224
NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr3_-_44778099 0.275 NM_020696
KIAA1143
KIAA1143
chr4_-_186693574 0.273 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr7_+_30140868 0.272 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr6_-_27988152 0.271 NM_033057
OR2B2
olfactory receptor, family 2, subfamily B, member 2
chr12_-_4624536 0.270 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr3_+_142143329 0.270 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr2_+_219779737 0.267 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr1_+_165564904 0.266 NM_001198783
POU2F1
POU class 2 homeobox 1
chr6_-_41810712 0.265 NM_007162
TFEB
transcription factor EB
chr2_+_113911737 0.265 NM_172003
CBWD2
CBWD1
COBW domain containing 2
COBW domain containing 1
chr12_-_121753795 0.265 NM_177551
GPR109A
G protein-coupled receptor 109A
chr5_+_36642213 0.263 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr16_+_66614645 0.263 NM_017803
DUS2L
dihydrouridine synthase 2-like, SMM1 homolog (S. cerevisiae)
chr2_-_224175339 0.261 SCG2
secretogranin II
chr3_-_188870799 0.260 NM_001048
SST
somatostatin
chr9_-_128924819 0.260 NM_012098
ANGPTL2
angiopoietin-like 2
chr7_+_128142661 0.260 NM_032599
FAM71F1
family with sequence similarity 71, member F1
chr1_+_196874839 0.259 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_+_39868126 0.258 DAAM2
dishevelled associated activator of morphogenesis 2
chr20_-_44034194 0.256 NM_022095
ZNF335
zinc finger protein 335
chr11_+_18372687 0.256 LDHA
lactate dehydrogenase A
chr5_-_175897430 0.253 RNF44
ring finger protein 44
chr1_-_227710619 0.252 NUP133
nucleoporin 133kDa
chr1_-_227710700 0.252 NM_018230
NUP133
nucleoporin 133kDa
chr6_-_136613097 0.252 NM_001099286
NM_138419
FAM54A

family with sequence similarity 54, member A

chr20_-_55718351 0.251 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr16_-_54424517 0.250 NM_001025194
NM_001025195
NM_001266
CES1


carboxylesterase 1


chr1_-_210275402 0.247 NM_015434
INTS7
integrator complex subunit 7
chr3_+_187866464 0.246 NM_000412
HRG
histidine-rich glycoprotein
chr5_+_140568451 0.246 NM_018932
PCDHB12
protocadherin beta 12
chr11_-_129803712 0.246 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr18_+_75261231 0.246 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr11_+_18372689 0.246 LDHA
lactate dehydrogenase A
chr11_+_116575249 0.246 NM_001001522
NM_003186
TAGLN

transgelin

chr7_-_135263737 0.245 MTPN
LUZP6
myotrophin
leucine zipper protein 6
chr1_+_27925054 0.244 NM_001143912
NM_001143913
NM_001143914
NM_001143915
NM_152660
FAM76A




family with sequence similarity 76, member A




chr12_-_31773210 0.243 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr12_-_49076658 0.243 NM_001145475
FAM186A
family with sequence similarity 186, member A
chr20_-_5539487 0.243 NM_019593
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr3_+_44778212 0.242 NM_020242
KIF15
kinesin family member 15
chr9_-_128924782 0.240 ANGPTL2
angiopoietin-like 2
chr17_-_19592178 0.239 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr17_-_70690525 0.237 SUMO2
SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae)
chr9_-_126573349 0.236 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr11_+_18372682 0.235 LDHA
lactate dehydrogenase A
chr10_-_64698831 0.235 NM_004241
JMJD1C
jumonji domain containing 1C
chr3_+_142569988 0.235 ZBTB38
zinc finger and BTB domain containing 38
chr10_+_80740584 0.235 ZMIZ1
zinc finger, MIZ-type containing 1
chr7_-_104696678 0.235 NM_182691
SRPK2
SRSF protein kinase 2
chr4_-_153493133 0.235 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr1_+_16203317 0.235 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr6_+_134800533 0.234 LOC154092
hypothetical LOC154092
chr15_+_87919744 0.234 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr2_-_99472843 0.232 REV1
REV1 homolog (S. cerevisiae)
chr2_-_160181206 0.232 NM_013450
BAZ2B
bromodomain adjacent to zinc finger domain, 2B
chr18_+_17607633 0.230 MIB1
mindbomb homolog 1 (Drosophila)
chr6_+_42896771 0.228 NM_015349
KIAA0240
KIAA0240
chr19_+_40716153 0.227 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_+_76516957 0.227 NM_000260
NM_001127179
NM_001127180
MYO7A


myosin VIIA


chr1_+_177261798 0.227 FAM20B
family with sequence similarity 20, member B
chr12_-_66933492 0.226 NM_020525
IL22
interleukin 22
chr9_+_139152595 0.226 GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr3_+_141879555 0.226 NM_152616
TRIM42
tripartite motif containing 42
chr1_-_25164061 0.226 NM_001031680
RUNX3
runt-related transcription factor 3
chr16_-_66614599 0.225 DDX28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr3_-_188945921 0.225 BCL6
B-cell CLL/lymphoma 6
chr19_+_48912053 0.225 NM_019612
IRGC
immunity-related GTPase family, cinema
chr9_-_128924706 0.225 ANGPTL2
angiopoietin-like 2
chr16_-_54424473 0.224 CES1
carboxylesterase 1
chr6_-_31778825 0.224 NM_001177515
ABHD16A
abhydrolase domain containing 16A
chr20_-_44034346 0.223 ZNF335
zinc finger protein 335
chr6_-_31740645 0.223 NM_033177
GPANK1
G patch domain and ankyrin repeats 1
chr11_+_18372708 0.222 LDHA
lactate dehydrogenase A
chr2_-_156897286 0.222 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr6_-_30631912 0.222 GNL1
guanine nucleotide binding protein-like 1
chr5_+_126140213 0.221 NM_005573
LMNB1
lamin B1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.18 3.73e-02 GO:0005634 nucleus

Nothing significant found in function category.