Mean activities

Top 10 and bottom 10 mean activities.

Mean activities

Mean activities sorted by motif Z-value.

Mean activities

Sorted mean activities for every motif.

Motif nameMean activityZ-ValueAssociated genesLogo
TBP.p2 0.136 0.634 TBP (TFIID)
REST.p3 0.131 0.346 REST (NRSF, XBR)
PAX6.p2 0.115 0.142 PAX6 (D11S812E, AN, WAGR)
RXRA_VDR{dimer}.p2 0.111 0.271 VDR (NR1I1)
GZF1.p2 0.107 0.096 GZF1 (dJ322G13.2, ZBTB23)
NKX2-1,4.p2 0.082 0.169 NKX2-1 (TTF-1)
NKX2-4 (NKX2.4)
HOXA9_MEIS1.p2 0.077 0.149 MEIS1
HOXA9
ZNF238.p2 0.076 0.297 ZNF238 (C2H2-171, TAZ-1, RP58, ZBTB18)
NR3C1.p2 0.073 0.217 NR3C1 (GR)
SRF.p3 0.065 0.188 SRF (MCM1)
NFE2L2.p2 0.064 0.235 NFE2L2 (NRF2)
ARID5B.p2 0.064 0.158 ARID5B (FLJ21150, MRF2)
STAT1,3.p3 0.054 0.124 STAT1 (STAT91, ISGF-3)
STAT3 (APRF)
NKX3-1.p2 0.050 0.202 NKX3-1 (NKX3.1, BAPX2)
HAND1,2.p2 0.047 0.180 HAND1 (eHand, Thing1, Hxt, bHLHa27)
HAND2 (dHand, Thing2, Hed, bHLHa26)
CRX.p2 0.047 0.267 CRX (CRD, LCA7, OTX3)
POU3F1..4.p2 0.046 0.144 POU3F1 (OCT6, SCIP)
POU3F3 (BRN1, OTF8)
POU3F2 (POUF3, BRN2, OCT7)
POU3F4 (BRN4, OTF9)
PITX1..3.p2 0.045 0.576 PITX2 (IGDS, RS, Brx1, Otlx2, ARP1)
PITX3
PITX1 (PTX1, POTX)
PAX8.p2 0.041 0.019 PAX8
PBX1.p2 0.038 0.148 PBX1
AR.p2 0.036 0.049 AR (AIS, NR3C4, SMAX1, HUMARA)
EN1,2.p2 0.035 0.142 EN1
EN2
FOS_FOS{B,L1}_JUN{B,D}.p2 0.035 0.202 FOS (c-fos, AP-1)
JUNB
FOSL1 (fra-1)
JUND (AP-1)
FOSB (G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818)
EOMES.p2 0.034 0.140 EOMES (TBR2)
HLF.p2 0.032 0.110 HLF (MGC33822)
HSF1,2.p2 0.032 0.244 HSF1 (HSTF1)
HSF2
NR5A1,2.p2 0.031 0.305 NR5A1 (FTZ1, SF-1, ELP, AD4BP)
NR5A2 (FTZ-F1beta, hB1F, LRH-1, FTZ-F1, hB1F-2, B1F2)
ZBTB16.p2 0.028 0.225 ZBTB16 (PLZF)
CEBPA,B_DDIT3.p2 0.026 0.065 DDIT3 (CHOP10, GADD153, CHOP)
CEBPA (C/EBP-alpha)
CEBPB (LAP, CRP2, NFIL6, IL6DBP)
CTCF.p2 0.025 0.149 CTCF
LEF1_TCF7_TCF7L1,2.p2 0.024 0.136 TCF7 (TCF-1)
TCF7L2 (TCF-4)
LEF1 (TCF1ALPHA)
TCF7L1
GLI1..3.p2 0.024 0.187 GLI1
GLI2 (THP2, HPE9, THP1)
GLI3 (PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV)
POU1F1.p2 0.024 0.102 POU1F1 (GHF-1)
EBF1.p2 0.024 0.232 EBF1 (OLF1)
NFIL3.p2 0.023 0.065 NFIL3 (E4BP4, NFIL3A, NF-IL3A)
NR1H4.p2 0.023 0.116 NR1H4 (FXR, RIP14, HRR1, HRR-1)
NKX2-2,8.p2 0.023 0.107 NKX2-2 (NKX2.2)
NKX2-8 (NKX2.8, Nkx2-9)
FOXQ1.p2 0.022 0.124 FOXQ1 (HFH1)
ATF4.p2 0.019 0.131 ATF4 (TAXREB67, CREB-2)
NANOG{mouse}.p2 0.019 0.062 NANOG (FLJ12581, FLJ40451)
SOX17.p2 0.018 0.161 SOX17
HOX{A5,B5}.p2 0.017 0.070 HOXB5
HOXA5
T.p2 0.017 0.033 T
PPARG.p2 0.016 0.035 PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
FOSL2.p2 0.015 0.068 FOSL2 (FRA2, FLJ23306)
IKZF2.p2 0.015 0.139 IKZF2 (Helios)
HMX1.p2 0.015 0.112 HMX1 (H6, NKX5-3)
EVI1.p2 0.014 0.082 EVI1 (MDS1-EVI1, PRDM3)
MEF2{A,B,C,D}.p2 0.014 0.093 MEF2A (RSRFC4, RSRFC9)
MEF2C
MEF2D
MEF2BNB-MEF2B (MEF2B, LOC729991-MEF2B)
MEF2B (RSRFR2, FLJ32648)
VSX1,2.p2 0.014 0.019 VSX2 (RET1)
VSX1 (PPD)
NKX6-1,2.p2 0.013 0.064 NKX6-1 (Nkx6.1)
NKX6-2 (NKX6B, GTX, NKX6.1)
MYOD1.p2 0.013 0.143 MYOD1 (PUM, MYOD, bHLHc1)
ZNF384.p2 0.013 0.129 ZNF384 (CAGH1A, CIZ, NMP4, NP)
GATA1..3.p2 0.013 0.223 GATA1 (ERYF1, NFE1)
GATA2 (NFE1B)
GATA3 (HDR)
TFAP4.p2 0.012 0.136 TFAP4 (AP-4)
ALX1.p2 0.012 0.048 ALX1
HMGA1,2.p2 0.011 0.123 HMGA1
HMGA2 (BABL, LIPO)
RREB1.p2 0.011 0.274 RREB1 (HNT)
STAT5{A,B}.p2 0.011 0.035 STAT5B
STAT5A (MGF)
DBP.p2 0.011 0.091 DBP (DABP)
HES1.p2 0.011 0.147 HES1 (FLJ20408, HES-1, Hes1, bHLHb39)
KLF12.p2 0.010 0.173 KLF12 (AP-2rep, HSPC122, AP2REP)
SOX5.p2 0.010 0.065 SOX5 (L-SOX5, MGC35153)
CDX1,2,4.p2 0.010 0.089 CDX1
CDX2
CDX4
SNAI1..3.p2 0.010 0.170 SNAI2 (SLUGH1)
SNAI1 (SNA, SLUGH2, SNAH)
SNAI3 (SMUC, Zfp293)
TLX2.p2 0.009 0.074 TLX2 (Enx, Tlx2, NCX)
ADNP_IRX_SIX_ZHX.p2 0.009 0.071 SIX5
ZHX1
IRX4
ADNP (KIAA0784, ADNP1)
ZHX3 (KIAA0395)
ZHX2 (KIAA0854)
IRX5 (IRX-2a)
SIX2
TCF4_dimer.p2 0.009 0.158 TCF4 (E2-2, ITF2, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19, MGC149723, MGC149724)
NKX3-2.p2 0.009 0.092 NKX3-2 (NKX3B, NKX3.2)
TGIF1.p2 0.009 0.054 TGIF1
HOX{A4,D4}.p2 0.009 0.058 HOXA4
HOXD4
MYBL2.p2 0.008 0.032 MYBL2 (BMYB, B-MYB)
GATA6.p2 0.008 0.033 GATA6
EWSR1-FLI1.p2 0.007 0.030 FLI1 (EWSR2, SIC-1)
EWSR1 (EWS, K984G1.4)
NFIX.p2 0.007 0.036 NFIX (NF1A)
TEAD1.p2 0.007 0.033 TEAD1 (TEF-1)
TEAD2 (ETF, TEF4, TEF-4, TEAD-2)
TEAD3 (TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3)
TEAD4 (TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B)
ESR1.p2 0.007 0.054 ESR1 (NR3A1, Era)
HIF1A.p2 0.006 0.063 HIF1A (MOP1, HIF-1alpha, PASD8, HIF1)
SMAD1..7,9.p2 0.006 0.050 SMAD5 (Dwfc, JV5-1)
SMAD1 (MADR1, JV4-1)
SMAD3 (JV15-2, HsT17436)
SMAD4 (DPC4)
SMAD2 (MADR2, JV18-1)
SMAD6 (HsT17432)
SMAD7
SMAD9
LMO2.p2 0.006 0.069 LMO2 (TTG2, RHOM2, RBTN2)
FOXL1.p2 0.006 0.040 FOXL1 (FREAC7, FKH6)
FOX{C1,C2}.p2 0.006 0.015 FOXC1 (FREAC3, ARA, IGDA, IHG1)
FOXC2 (MFH-1)
BPTF.p2 0.005 0.108 BPTF (FAC1, NURF301)
NFKB1_REL_RELA.p2 0.005 0.047 RELA (p65)
REL (I-Rel)
NFKB1 (KBF1, p105)
PATZ1.p2 0.005 0.183 PATZ1 (MAZR, dJ400N23, ZBTB19, ZSG, RIAZ, PATZ)
FOXD3.p2 0.005 0.057 FOXD3 (Genesis, HFH2)
TFAP2B.p2 0.004 0.174 TFAP2B (AP2-B)
RORA.p2 0.004 0.008 RORA (RZRA, ROR1, ROR2, ROR3, NR1F1)
HNF4A_NR2F1,2.p2 0.004 0.042 NR2F1 (EAR-3, COUP-TFI, TCFCOUP1, SVP44)
NR2F2 (COUP-TFII, COUPTFB, SVP40)
HNF4A (NR2A1, HNF4)
FOX{D1,D2}.p2 0.004 0.020 FOXD2 (FREAC9)
FOXD1 (FREAC4)
HIC1.p2 0.004 0.108 HIC1 (ZBTB29)
TFAP2{A,C}.p2 0.004 0.202 TFAP2C (AP2-GAMMA, ERF1, TFAP2G, hAP-2g)
TFAP2A (AP-2)
PRRX1,2.p2 0.003 0.062 PRRX2 (PRX2, PMX2)
PRRX1 (PHOX1)
ONECUT1,2.p2 0.003 0.015 ONECUT2 (OC-2)
ONECUT1 (HNF-6)
NFATC1..3.p2 0.003 0.029 NFATC3 (NFAT4, NFATX)
NFATC2 (NF-ATP, NFATp, NFAT1)
NFATC1 (NF-ATC, NFATc, NFAT2)
TFCP2.p2 0.003 0.052 TFCP2 (CP2, LSF, LBP-1C, TFCP2C)
ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2 0.002 0.018 ARNT (HIF-1beta, bHLHe2)
MAX (bHLHd4)
MYC (c-Myc, bHLHe39)
USF1 (UEF, MLTFI, bHLHb11)
BHLHB2 (DEC1, bHLHe40)
ARNT2 (KIAA0307, bHLHe1)
ETS1,2.p2 0.002 0.030 ETS2
ETS1 (FLJ10768, ETS-1)
FOX{F1,F2,J1}.p2 0.002 0.009 FOXF2 (FREAC2)
FOXJ1 (HFH-4, HFH4)
FOXF1 (FREAC1)
YY1.p2 0.002 0.053 YY1 (NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S)
SPZ1.p2 0.002 0.030 SPZ1 (NYD-TSP1, FLJ25709)
TFDP1.p2 0.002 0.094 TFDP1 (Dp-1, DRTF1, DP1)
NFE2L1.p2 0.002 0.031 NFE2L1 (NRF1, LCR-F1, FLJ00380, TCF11)
MTF1.p2 0.002 0.039 MTF1
MAFB.p2 0.002 0.036 MAFB
HOX{A6,A7,B6,B7}.p2 0.001 0.029 HOXB6
HOXA7
HOXB7
HOXA6
EGR1..3.p2 0.001 0.022 EGR3 (PILOT)
EGR1 (TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225)
EGR2
PAX2.p2 0.001 0.007 PAX2
GTF2I.p2 0.001 0.016 GTF2I (TFII-I, BAP-135, SPIN, BTKAP1, DIWS, IB291)
ZNF148.p2 0.000 0.009 ZNF148 (BERF-1, ZBP-89, BFCOL1, HT-BETA, ZFP148, pHZ-52)
TBX4,5.p2 0.000 0.004 TBX5
TBX4
FOXO1,3,4.p2 0.000 0.003 FOXO1 (FKH1)
FOXO4 (AFX1)
FOXO3 (AF6q21, FOXO2)
HBP1_HMGB_SSRP1_UBTF.p2 -0.000 -0.003 HMGB2
HMGB3 (HMG2A, MGC90319)
SSRP1 (FACT80)
UBTF (UBF, NOR-90)
HBP1
POU5F1_SOX2{dimer}.p2 -0.000 -0.002 POU5F1 (OCT3, Oct4, MGC22487)
SOX2
MAZ.p2 -0.001 -0.023 MAZ (ZF87, Pur-1, Zif87, ZNF801)
PAX5.p2 -0.001 -0.028 PAX5 (BSAP)
HNF1A.p2 -0.001 -0.003 HNF1A (HNF1, LFB1)
POU5F1.p2 -0.001 -0.010 POU5F1 (OCT3, Oct4, MGC22487)
TLX1..3_NFIC{dimer}.p2 -0.001 -0.006 TLX1
TLX3 (RNX)
NKX2-3_NKX2-5.p2 -0.002 -0.008 NKX2-5 (CSX1, NKX2.5, NKX4-1)
NKX2-3 (NKX2.3, CSX3, NKX4-3)
SRY.p2 -0.002 -0.014 SRY (TDF)
LHX3,4.p2 -0.002 -0.008 LHX3
LHX4 (Gsh4)
FOXN1.p2 -0.002 -0.011 FOXN1 (FKHL20)
RUNX1..3.p2 -0.003 -0.024 RUNX1 (PEBP2A2, AMLCR1)
RUNX3 (AML2, PEBP2A3)
RUNX2 (AML3, PEBP2A1, PEBP2aA1)
PDX1.p2 -0.003 -0.004 PDX1 (IDX-1, STF-1, PDX-1, MODY4)
ATF6.p2 -0.003 -0.025 ATF6 (ATF6A)
EP300.p2 -0.004 -0.046 EP300 (p300, KAT3B)
STAT2,4,6.p2 -0.004 -0.043 STAT2 (STAT113)
STAT4
STAT6 (D12S1644, IL-4-STAT)
FOXP3.p2 -0.004 -0.010 FOXP3 (JM2, XPID, AIID, PIDX, DIETER, SCURFIN)
KLF4.p3 -0.005 -0.181 KLF4 (EZF, GKLF)
ZBTB6.p2 -0.005 -0.059 ZBTB6 (ZID)
SPIB.p2 -0.005 -0.098 SPIB (SPI-B)
SOX2.p2 -0.005 -0.044 SOX2
SOX{8,9,10}.p2 -0.005 -0.039 SOX9 (SRA1)
SOX8
SOX10 (DOM, WS4, WS2E)
TFEB.p2 -0.005 -0.041 TFEB
AIRE.p2 -0.005 -0.016 AIRE (PGA1, APS1)
MZF1.p2 -0.006 -0.212 MZF1 (MZF1B, ZSCAN6, MZF-1, Zfp98)
bHLH_family.p2 -0.006 -0.078 ARNTL (MOP3, JAP3, BMAL1, PASD3, bHLHe5)
MITF (WS2A, MI, bHLHe32)
MXI1 (MXD2, MAD2, MXI, bHLHc11)
TFE3 (TFEA, bHLHe33)
CLOCK (KIAA0334, KAT13D, bHLHe8)
OLIG2 (RACK17, OLIGO2, bHLHe19)
MXD4 (MAD4, MSTP149, MST149, bHLHc12)
HEY2 (bHLHb32)
HEY1 (HESR-1, CHF2, HESR1, HRT-1, CHF-2, HERP2, BHLHb31)
HEYL (bHLHb33)
MLXIPL (WS-bHLH, MIO, CHREBP, MONDOB)
HES6 (bHLHc23)
MXD3 (MAD3, bHLHc13)
ARNTL2 (BMAL2, MOP9, CLIF, PASD9, bHLHe6)
ID1 (dJ857M17.1.2, bHLHb24)
MNT (ROX, MXD6, MAD6, bHLHd3)
OLIG1 (BHLHB6, bHLHe21)
NPAS2 (MOP4, PASD4, bHLHe9)
ZFP161.p2 -0.007 -0.165 ZFP161 (ZNF478, ZBTB14)
SP1.p2 -0.007 -0.322 SP1
FEV.p2 -0.007 -0.115 FEV (PET-1, HSRNAFEV)
JUN.p2 -0.007 -0.065 JUN (c-Jun, AP-1)
JUND (AP-1)
JUNB
ATF5_CREB3.p2 -0.008 -0.074 ATF5
CREB3 (LZIP, Luman)
ZNF423.p2 -0.008 -0.050 ZNF423 (KIAA0760, OAZ, Roaz, Ebfaz, Zfp104)
AHR_ARNT_ARNT2.p2 -0.008 -0.127 ARNT (HIF-1beta, bHLHe2)
AHR
ARNT2 (KIAA0307, bHLHe1)
GFI1.p2 -0.008 -0.085 GFI1
MYFfamily.p2 -0.009 -0.188 MYOD1 (PUM, MYOD, bHLHc1)
MYF6 (MRF4, bHLHc4)
MYF5 (bHLHc2)
MYOG (bHLHc3)
NHLH1,2.p2 -0.009 -0.179 NHLH1 (NSCL, NSCL1, bHLHa35)
NHLH2 (NSCL2, bHLHa34)
FOX{I1,J2}.p2 -0.009 -0.089 FOXI1 (FREAC6)
FOXJ2 (FHX)
FOXA2.p3 -0.010 -0.052 FOXA2
IKZF1.p2 -0.010 -0.071 IKZF1 (hIk-1, LyF-1, Hs.54452, IKAROS)
GTF2A1,2.p2 -0.011 -0.068 GTF2A1 (TFIIA)
GTF2A2 (TFIIA, HsT18745)
ZIC1..3.p2 -0.011 -0.090 ZIC1 (ZIC, ZNF201)
ZIC2 (HPE5)
ZIC3 (HTX, ZNF203)
DMAP1_NCOR{1,2}_SMARC.p2 -0.011 -0.052 SMARCA1 (SNF2LB, NURF140, ISWI, SWI)
SMARCC2 (BAF170, Rsc8, CRACC2)
SMARCA5 (hSNF2H, hISWI, ISWI)
NCOR1 (N-CoR, hCIT529I10, TRAC1, hN-CoR, KIAA1047, MGC104216)
NCOR2 (SMRT, SMRTE, TRAC-1, CTG26, TNRC14)
DMAP1 (DNMAP1, FLJ11543, KIAA1425, DNMTAP1, EAF2, SWC4)
RBPJ.p2 -0.012 -0.066 RBPJ (SUH, IGKJRB, RBPJK, KBF2, RBP-J, CBF1)
CDC5L.p2 -0.014 -0.052 CDC5L (PCDC5RP, hCDC5, CEF1)
ZEB1.p2 -0.014 -0.193 ZEB1 (BZP, ZEB, AREB6, NIL-2-A, Zfhep, Zfhx1a)
EHF.p2 -0.015 -0.173 EHF
SPI1.p2 -0.015 -0.361 SPI1 (PU.1, SPI-A, OF, SFPI1, SPI-1)
NR6A1.p2 -0.015 -0.026 NR6A1 (GCNF1, RTR)
RXR{A,B,G}.p2 -0.017 -0.184 RXRA (NR2B1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
CUX2.p2 -0.017 -0.026 CUX2 (KIAA0293, CDP2)
POU2F1..3.p2 -0.020 -0.088 POU2F2 (OCT2)
POU2F1 (OCT1)
POU2F3 (OCT11, PLA-1, Skn-1a, Epoc-1)
NRF1.p2 -0.020 -0.401 NRF1 (EWG, ALPHA-PAL)
ELF1,2,4.p2 -0.020 -0.383 ELF2 (EU32, NERF, NERF-2, NERF-1A, NERF-1B)
ELF1
ELF4 (MEF, ELFR)
ATF2.p2 -0.024 -0.147 ATF2 (TREB7, CRE-BP1, HB16)
PRDM1.p3 -0.025 -0.070 PRDM1 (PRDI-BF1)
RFX1..5_RFXANK_RFXAP.p2 -0.026 -0.209 RFX1 (EF-C)
RFXAP
RFX5
RFXANK (BLS, RFX-B, ANKRA1, F14150_1, MGC138628)
RFX4
RFX3
RFX2 (FLJ14226)
MYB.p2 -0.027 -0.266 MYB (c-myb)
NFY{A,B,C}.p2 -0.027 -0.366 NFYC (CBF-C)
NFYB (CBF-A, HAP3)
NFYA (HAP2, CBF-B)
ELK1,4_GABP{A,B1}.p3 -0.027 -0.414 GABPA (E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A)
GABPB1 (E4TF1-47, GABPB)
ELK4 (SAP1)
ELK1
PAX4.p2 -0.027 -0.124 PAX4
TP53.p2 -0.030 -0.124 TP53 (p53, LFS1)
IRF1,2,7.p3 -0.033 -0.184 IRF1 (MAR, IRF-1)
IRF2 (IRF-2, DKFZp686F0244)
IRF7 (IRF7A, IRF-7H)
ESRRA.p2 -0.034 -0.182 ESRRA (ERR1, ERRalpha, NR3B1, ERRa)
POU6F1.p2 -0.035 -0.101 POU6F1 (BRN5, MPOU, TCFB1)
CREB1.p2 -0.036 -0.266 CREB1
SREBF1,2.p2 -0.036 -0.195 SREBF1 (SREBP1, bHLHd1)
SREBF2 (SREBP2, bHLHd2)
ZNF143.p2 -0.037 -0.518 ZNF143 (SBF, pHZ-1, STAF)
E2F1..5.p2 -0.041 -0.322 E2F4 (E2F-4)
E2F5
E2F2 (E2F-2)
E2F1 (RBP3)
E2F3
TAL1_TCF{3,4,12}.p2 -0.041 -0.089 TCF3 (E2A, ITF1, MGC129647, MGC129648, bHLHb21)
TCF4 (SEF2-1B, ITF2, bHLHb19)
TAL1 (SCL, bHLHa17)
TCF12 (HEB, HTF4, HsT17266, bHLHb20)
XBP1.p3 -0.044 -0.155 XBP1
RXRG_dimer.p3 -0.049 -0.141 NR1H2 (NER, NER-I, RIP15, LXR-b)
RXRA (NR2B1)
PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
PPARA (hPPAR, NR1C1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
BACH2.p2 -0.050 -0.177 BACH2
GFI1B.p2 -0.050 -0.158 GFI1B
NANOG.p2 -0.051 -0.175 NANOG (FLJ12581, FLJ40451)
NFE2.p2 -0.071 -0.282 NFE2 (NF-E2)
MSX1,2.p2 -0.080 -0.142 MSX1 (HYD1, OFC5)
MSX2 (CRS2, FPP, HOX8, MSH, PFM)
PAX3,7.p2 -0.277 -0.117 PAX7 (Hup1)
PAX3 (HUP2)