• All motifs sorted by activity significance
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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 2.234

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_120378052	2.915	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr10_+_62208256	2.545		CDK1	cyclin-dependent kinase 1
chr10_+_62208094	2.536	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr2_+_173927783	2.156	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr10_+_96295511	1.952	NM_018063	HELLS	helicase, lymphoid-specific
chr1_+_143920424	1.787	NM_203458	NOTCH2NL	notch 2 N-terminal like
chr7_+_93977267	1.605		CASD1	CAS1 domain containing 1
chr6_+_20510019	1.595	NM_001949	E2F3	E2F transcription factor 3
chr11_+_86426518	1.594	NM_001168724 NM_022918	TMEM135	transmembrane protein 135
chr1_+_26671548	1.552		HMGN2	high-mobility group nucleosomal binding domain 2
chr5_+_139473873	1.482	NM_005859	PURA	purine-rich element binding protein A
chrX_+_44617346	1.476	NM_021140	KDM6A	lysine (K)-specific demethylase 6A
chr2_+_48395271	1.464	NM_002158	FOXN2	forkhead box N2
chr1_+_113734997	1.423	NM_001142782 NM_152900	MAGI3	membrane associated guanylate kinase, WW and PDZ domain containing 3
chr5_+_56505608	1.419		GPBP1	GC-rich promoter binding protein 1
chr1_+_210848726	1.395		ATF3	activating transcription factor 3
chr1_+_210848763	1.345		ATF3	activating transcription factor 3
chr15_+_97923655	1.303	NM_001130926 NM_001130927 NM_001171894 NM_005587	MEF2A	myocyte enhancer factor 2A
chr13_+_97426713	1.293		IPO5	importin 5
chr1_+_6767968	1.260	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr7_+_93976927	1.250	NM_022900	CASD1	CAS1 domain containing 1
chr13_+_33290254	1.246		RFC3	replication factor C (activator 1) 3, 38kDa
chr6_+_108988797	1.238		FOXO3	forkhead box O3
chr7_+_138695144	1.233	NM_016019	LUC7L2	LUC7-like 2 (S. cerevisiae)
chr15_+_97923702	1.226		MEF2A	myocyte enhancer factor 2A
chr10_+_112317401	1.209	NM_005445	SMC3	structural maintenance of chromosomes 3
chr1_+_93317374	1.198	NM_001164391 NM_001164392 NM_001164393 NM_007358	MTF2	metal response element binding transcription factor 2
chr7_+_32734244	1.194		LOC441208	zinc and ring finger 2 pseudogene
chr6_+_3966499	1.166	NM_003913	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr1_+_3558958	1.164	NM_005427	TP73	tumor protein p73
chr3_+_16901455	1.164	NM_001144382	PLCL2	phospholipase C-like 2
chr9_-_97119677	1.156	NM_000136	FANCC	Fanconi anemia, complementation group C
chr7_+_138695209	1.152		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr6_+_24883133	1.143	NM_015895	GMNN	geminin, DNA replication inhibitor
chr15_+_97923737	1.129		MEF2A	myocyte enhancer factor 2A
chr9_+_17124974	1.115	NM_001114395 NM_017738	CNTLN	centlein, centrosomal protein
chr5_-_39110235	1.108		RICTOR	RPTOR independent companion of MTOR, complex 2
chr17_+_26183074	1.108	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr1_+_210848592	1.107	NM_001040619 NM_001674	ATF3	activating transcription factor 3
chr2_+_219141761	1.103	NM_005444	RQCD1	RCD1 required for cell differentiation1 homolog (S. pombe)
chr4_+_106287391	1.096	NM_001127208 NM_017628	TET2	tet oncogene family member 2
chr3_+_41215926	1.096	NM_001098209 NM_001098210 NM_001904	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr7_+_88226617	1.090	NM_181646	ZNF804B	zinc finger protein 804B
chr5_+_36912656	1.090		NIPBL	Nipped-B homolog (Drosophila)
chr7_+_138695236	1.082		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr20_-_35157744	1.079		RBL1	retinoblastoma-like 1 (p107)
chr12_-_61283474	1.066	NM_175895	C12orf61	chromosome 12 open reading frame 61
chr17_+_54997667	1.051	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr9_+_494661	1.042	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr5_-_39110251	1.027	NM_152756	RICTOR	RPTOR independent companion of MTOR, complex 2
chr5_+_65476418	1.016	NM_139168	SREK1	splicing regulatory glutamine/lysine-rich protein 1
chr7_+_138695241	1.000		LUC7L2	LUC7-like 2 (S. cerevisiae)
chr2_-_175754366	0.978	NM_001002258 NM_001190329 NM_001689	ATP5G3	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
chr4_+_72078126	0.972	NM_000788	DCK	deoxycytidine kinase
chr6_-_27914095	0.972	NM_003510	HIST1H2AK	histone cluster 1, H2ak
chr2_+_131966970	0.970		LOC150776	sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr7_+_64136078	0.964		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_-_26105230	0.961	NM_203401	STMN1	stathmin 1
chr6_+_27208763	0.961	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr6_-_41971064	0.946	NM_018561	USP49	ubiquitin specific peptidase 49
chr4_+_72078255	0.935		DCK	deoxycytidine kinase
chr6_-_56816403	0.929		DST	dystonin
chr20_-_35157815	0.926	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr2_+_170149348	0.924		PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr1_+_115198977	0.915	NM_003176	SYCP1	synaptonemal complex protein 1
chr1_+_169721260	0.914	NM_015172	PRRC2C	proline-rich coiled-coil 2C
chr1_-_91260357	0.911		ZNF644	zinc finger protein 644
chr2_+_177785667	0.909	NM_194247	HNRNPA3P1 HNRNPA3	heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 heterogeneous nuclear ribonucleoprotein A3
chr5_+_56505412	0.906	NM_022913	GPBP1	GC-rich promoter binding protein 1
chr1_+_177261678	0.898	NM_014864	FAM20B	family with sequence similarity 20, member B
chr5_+_78568094	0.890
chr2_+_149118791	0.887		EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr6_+_44463418	0.884		CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr13_+_33290205	0.881	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chr7_+_86619805	0.876	NM_021145	DMTF1	cyclin D binding myb-like transcription factor 1
chr20_-_31737731	0.874		E2F1	E2F transcription factor 1
chr7_+_94123672	0.872		PEG10	paternally expressed 10
chr7_+_86619580	0.869	NM_001142326 NM_001142327	DMTF1	cyclin D binding myb-like transcription factor 1
chr2_+_149119029	0.863	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr14_+_85069217	0.856
chr2_+_171493870	0.841	NM_015530	GORASP2	golgi reassembly stacking protein 2, 55kDa
chr15_+_28705656	0.841		ARHGAP11B	Rho GTPase activating protein 11B
chr8_+_94998258	0.841	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr6_-_27208507	0.839	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr10_+_75580914	0.835	NM_006721	ADK	adenosine kinase
chr1_-_26105477	0.829	NM_001145454 NM_005563	STMN1	stathmin 1
chr13_-_109236897	0.825	NM_003749	IRS2	insulin receptor substrate 2
chr1_+_177261627	0.825		FAM20B	family with sequence similarity 20, member B
chr4_-_74154272	0.825	NM_173827	COX18	COX18 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr2_+_153283381	0.822		ARL6IP6	ADP-ribosylation-like factor 6 interacting protein 6
chr5_+_36912595	0.818	NM_015384 NM_133433	NIPBL	Nipped-B homolog (Drosophila)
chr15_+_30694982	0.816	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr15_+_39739933	0.815		MGA	MAX gene associated
chr4_+_120353177	0.810
chr3_+_41215999	0.803		CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa
chr6_+_27914301	0.801	NM_003520	HIST1H2BN	histone cluster 1, H2bn
chr1_+_61320213	0.799	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr21_+_29592984	0.789		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr14_+_34521945	0.784		SRP54	signal recognition particle 54kDa
chr15_+_39739864	0.783	NM_001080541 NM_001164273	MGA	MAX gene associated
chr2_-_219141199	0.781	NM_020935	USP37	ubiquitin specific peptidase 37
chr1_+_26671488	0.779	NM_005517	HMGN2	high-mobility group nucleosomal binding domain 2
chr5_-_36912487	0.779		LOC646719	hypothetical LOC646719
chr1_-_120413798	0.778	NM_024408	NOTCH2	notch 2
chr6_-_27883662	0.777	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr7_+_30291136	0.774		ZNRF2	zinc and ring finger 2
chr7_+_90063543	0.774		CDK14	cyclin-dependent kinase 14
chr13_+_78953495	0.771		NDFIP2	Nedd4 family interacting protein 2
chr6_+_108988761	0.769	NM_001455	FOXO3	forkhead box O3
chr13_+_78953367	0.763		NDFIP2	Nedd4 family interacting protein 2
chr11_+_125001063	0.763		CHEK1	CHK1 checkpoint homolog (S. pombe)
chr6_+_135544214	0.762		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr4_+_39734902	0.757	NM_018177	N4BP2	NEDD4 binding protein 2
chr22_+_18485068	0.753		RANBP1	RAN binding protein 1
chr6_+_44463265	0.750	NM_001253	CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr20_-_31737815	0.750	NM_005225	E2F1	E2F transcription factor 1
chr6_-_116681863	0.749	NM_021648	TSPYL4	TSPY-like 4
chr2_+_170149092	0.746	NM_004792	PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr7_-_106088565	0.743	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr6_+_27883877	0.741	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr2_+_153283375	0.739		ARL6IP6	ADP-ribosylation-like factor 6 interacting protein 6
chr21_+_29593088	0.731	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_+_5879297	0.726	NM_032485 NM_182802	MCM8	minichromosome maintenance complex component 8
chr4_+_120353212	0.724	NM_019050	USP53	ubiquitin specific peptidase 53
chr1_+_109434896	0.722	NM_020141	TMEM167B	transmembrane protein 167B
chr13_+_78953258	0.722	NM_001161407 NM_019080	NDFIP2	Nedd4 family interacting protein 2
chr7_+_30291029	0.721		ZNRF2	zinc and ring finger 2
chr14_+_35365266	0.719	NM_032352	BRMS1L	breast cancer metastasis-suppressor 1-like
chr17_+_40089270	0.716	NM_001145080	C17orf104	chromosome 17 open reading frame 104
chr9_+_99785493	0.714		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr2_+_171494026	0.711		GORASP2	golgi reassembly stacking protein 2, 55kDa
chr15_+_54444907	0.708	NM_198524	TEX9	testis expressed 9
chr7_+_94123612	0.707	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr6_+_64403668	0.704		PHF3	PHD finger protein 3
chr15_+_42507057	0.700		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr6_+_64403631	0.699		PHF3	PHD finger protein 3
chr1_+_52380633	0.697	NM_004799 NM_007323 NM_007324	ZFYVE9	zinc finger, FYVE domain containing 9
chr11_+_73981274	0.693	NM_006591	POLD3	polymerase (DNA-directed), delta 3, accessory subunit
chr6_+_64403685	0.692		PHF3	PHD finger protein 3
chr3_+_144203061	0.692	NM_001080415	U2SURP	U2 snRNP-associated SURP domain containing
chr5_-_74098641	0.690	NM_032380 NM_170681 NM_170691	GFM2	G elongation factor, mitochondrial 2
chr2_+_153283353	0.684		ARL6IP6	ADP-ribosylation-like factor 6 interacting protein 6
chr1_-_26105954	0.677	NM_203399	STMN1	stathmin 1
chr1_-_23730298	0.675	NM_004091	E2F2	E2F transcription factor 2
chr7_-_94123362	0.674		SGCE	sarcoglycan, epsilon
chr7_-_94123308	0.672		SGCE	sarcoglycan, epsilon
chr6_-_91353492	0.665	NM_003188 NM_145332 NM_145333	MAP3K7	mitogen-activated protein kinase kinase kinase 7
chr9_+_95253732	0.665	NM_014612	FAM120A	family with sequence similarity 120A
chr14_+_50776635	0.664	NM_030755	TMX1	thioredoxin-related transmembrane protein 1
chr1_+_28029922	0.660		PPP1R8	protein phosphatase 1, regulatory (inhibitor) subunit 8
chr9_-_103289154	0.660	NM_032342	C9orf125	chromosome 9 open reading frame 125
chr1_-_120413783	0.656		NOTCH2	notch 2
chr1_+_62675323	0.651		USP1	ubiquitin specific peptidase 1
chr4_+_148758014	0.650		TMEM184C	transmembrane protein 184C
chr21_+_29593098	0.650		BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr7_-_94123413	0.649	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr3_+_113180517	0.646	NM_018394	ABHD10	abhydrolase domain containing 10
chr6_+_139497933	0.645	NM_016217	HECA	headcase homolog (Drosophila)
chr1_+_28029909	0.640		PPP1R8	protein phosphatase 1, regulatory (inhibitor) subunit 8
chr10_+_13243553	0.639	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr7_+_94123556	0.638	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr7_-_77163475	0.632
chr12_+_70519753	0.629	NM_001146213 NM_001146214 NM_022771	TBC1D15	TBC1 domain family, member 15
chr1_+_28029879	0.628	NM_002713 NM_014110 NM_138558	PPP1R8	protein phosphatase 1, regulatory (inhibitor) subunit 8
chr1_+_205992032	0.627		CD46	CD46 molecule, complement regulatory protein
chr4_+_152240182	0.626	NM_001006	RPS3A	ribosomal protein S3A
chr5_+_75414994	0.624	NM_014979	SV2C	synaptic vesicle glycoprotein 2C
chr1_+_62675296	0.624		USP1	ubiquitin specific peptidase 1
chr1_-_120413698	0.623		NOTCH2	notch 2
chr1_-_91260181	0.623	NM_032186 NM_201269	ZNF644	zinc finger protein 644
chr15_+_42507123	0.621		CTDSPL2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr1_-_39097904	0.620	NM_022157	RRAGC	Ras-related GTP binding C
chr17_+_26082779	0.619		SUZ12P	suppressor of zeste 12 homolog pseudogene
chr8_+_21833162	0.615		XPO7	exportin 7
chr22_+_18485145	0.614		RANBP1	RAN binding protein 1
chr6_+_64403936	0.613		PHF3	PHD finger protein 3
chr6_+_157141565	0.611		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr4_+_148757958	0.610	NM_018241	TMEM184C	transmembrane protein 184C
chr7_-_151764004	0.606	NM_170606	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3
chr6_+_163755773	0.606		QKI	quaking homolog, KH domain RNA binding (mouse)
chr2_+_64605049	0.595		AFTPH	aftiphilin
chr5_+_72287509	0.595	NM_001146032 NM_138782	FCHO2	FCH domain only 2
chr5_+_138657317	0.594	NM_001194955 NM_001194956	MATR3	matrin 3
chr20_-_48980858	0.592	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr11_+_9552005	0.590		WEE1	WEE1 homolog (S. pombe)
chr11_+_9551885	0.589		WEE1	WEE1 homolog (S. pombe)
chr5_+_138657229	0.588	NM_018834	MATR3	matrin 3
chrX_+_130985316	0.587	NM_001042452	MST4	serine/threonine protein kinase MST4
chr9_+_85785456	0.587	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr14_+_34521854	0.579	NM_001146282 NM_003136	SRP54	signal recognition particle 54kDa
chr1_+_100371293	0.579	NM_019083	CCDC76	coiled-coil domain containing 76
chr1_-_100370994	0.574	NM_194292	SASS6	spindle assembly 6 homolog (C. elegans)
chr8_+_21833111	0.574	NM_015024	XPO7	exportin 7
chr16_+_71256497	0.573
chr20_-_21326046	0.573	NM_033176	NKX2-4	NK2 homeobox 4
chr15_+_66133625	0.571	NM_016166	PIAS1	protein inhibitor of activated STAT, 1
chr20_+_36095263	0.570	NM_021215	RPRD1B	regulation of nuclear pre-mRNA domain containing 1B
chr6_+_27969181	0.570	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr9_-_122679387	0.569	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr5_+_72287625	0.569

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.47	1.99e-19	GO:0044260	cellular macromolecule metabolic process
1.64	2.48e-18	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.13	4.02e-17	GO:0007049	cell cycle
2.49	1.20e-16	GO:0051276	chromosome organization
1.68	1.07e-15	GO:0090304	nucleic acid metabolic process
1.32	3.15e-15	GO:0044237	cellular metabolic process
1.37	7.09e-14	GO:0043170	macromolecule metabolic process
1.50	2.44e-13	GO:0034641	cellular nitrogen compound metabolic process
1.47	1.45e-12	GO:0006807	nitrogen compound metabolic process
2.10	2.37e-12	GO:0022402	cell cycle process
1.73	2.62e-12	GO:0006996	organelle organization
4.37	7.09e-12	GO:0065004	protein-DNA complex assembly
2.18	7.34e-12	GO:0022403	cell cycle phase
4.25	8.51e-12	GO:0071824	protein-DNA complex subunit organization
1.28	8.57e-12	GO:0044238	primary metabolic process
1.15	1.15e-11	GO:0009987	cellular process
2.39	1.18e-10	GO:0006325	chromatin organization
3.69	3.36e-10	GO:0006333	chromatin assembly or disassembly
1.42	4.28e-10	GO:0016043	cellular component organization
1.41	4.31e-10	GO:0071840	cellular component organization or biogenesis
4.26	5.37e-10	GO:0031497	chromatin assembly
4.21	3.91e-09	GO:0006334	nucleosome assembly
1.23	4.84e-09	GO:0008152	metabolic process
2.02	6.72e-09	GO:0065003	macromolecular complex assembly
2.12	9.96e-09	GO:0006259	DNA metabolic process
3.93	1.48e-08	GO:0034728	nucleosome organization
2.10	2.93e-08	GO:0000278	mitotic cell cycle
1.44	3.59e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.71	7.53e-08	GO:0044085	cellular component biogenesis
3.46	8.86e-08	GO:0006323	DNA packaging
1.44	9.85e-08	GO:0071842	cellular component organization at cellular level
2.37	1.14e-07	GO:0034622	cellular macromolecular complex assembly
3.22	1.26e-07	GO:0071103	DNA conformation change
2.10	2.02e-07	GO:0016071	mRNA metabolic process
1.73	3.32e-07	GO:0022607	cellular component assembly
2.46	4.67e-07	GO:0051325	interphase
1.81	1.11e-06	GO:0043933	macromolecular complex subunit organization
1.53	1.20e-06	GO:0016070	RNA metabolic process
2.41	2.03e-06	GO:0051329	interphase of mitotic cell cycle
2.11	6.85e-06	GO:0000279	M phase
2.79	7.17e-06	GO:0006260	DNA replication
1.99	1.47e-05	GO:0006974	response to DNA damage stimulus
1.98	3.65e-05	GO:0034621	cellular macromolecular complex subunit organization
1.85	4.11e-05	GO:0006396	RNA processing
1.76	5.90e-05	GO:0071844	cellular component assembly at cellular level
1.45	7.10e-05	GO:0010467	gene expression
2.15	1.24e-04	GO:0006281	DNA repair
1.37	1.48e-04	GO:0044249	cellular biosynthetic process
1.46	2.09e-04	GO:0034645	cellular macromolecule biosynthetic process
2.05	2.44e-04	GO:0006397	mRNA processing
1.44	4.73e-04	GO:0009059	macromolecule biosynthetic process
1.78	5.24e-04	GO:0051726	regulation of cell cycle
2.73	7.67e-04	GO:0000082	G1/S transition of mitotic cell cycle
2.04	9.45e-04	GO:0051301	cell division
1.34	1.04e-03	GO:0009058	biosynthetic process
1.63	1.70e-03	GO:0033554	cellular response to stress
6.32	2.00e-03	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
2.11	2.06e-03	GO:0000280	nuclear division
2.11	2.06e-03	GO:0007067	mitosis
1.97	2.96e-03	GO:0016568	chromatin modification
1.32	3.79e-03	GO:0044267	cellular protein metabolic process
1.33	4.18e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.06	4.67e-03	GO:0000087	M phase of mitotic cell cycle
2.05	5.16e-03	GO:0048285	organelle fission
1.31	6.45e-03	GO:0010556	regulation of macromolecule biosynthetic process
6.32	7.31e-03	GO:0007062	sister chromatid cohesion
1.26	7.63e-03	GO:0060255	regulation of macromolecule metabolic process
2.76	9.41e-03	GO:0051320	S phase
2.01	1.10e-02	GO:0008380	RNA splicing
3.41	1.21e-02	GO:0031124	mRNA 3'-end processing
2.53	1.38e-02	GO:0006310	DNA recombination
2.24	1.55e-02	GO:0000375	RNA splicing, via transesterification reactions
1.66	1.87e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.29	1.92e-02	GO:0010468	regulation of gene expression
2.23	2.28e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.23	2.28e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
2.69	2.29e-02	GO:0000084	S phase of mitotic cell cycle
1.28	2.58e-02	GO:0031326	regulation of cellular biosynthetic process
1.28	2.92e-02	GO:0009889	regulation of biosynthetic process
1.50	3.27e-02	GO:0009892	negative regulation of metabolic process
2.57	3.36e-02	GO:0050657	nucleic acid transport
2.57	3.36e-02	GO:0050658	RNA transport
2.57	3.36e-02	GO:0051236	establishment of RNA localization
4.10	3.97e-02	GO:0051318	G1 phase
1.51	4.35e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.22	4.57e-02	GO:0031323	regulation of cellular metabolic process
2.89	4.63e-02	GO:0006402	mRNA catabolic process
1.61	4.99e-02	GO:0010558	negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.34	5.65e-47	GO:0043229	intracellular organelle
1.34	6.46e-47	GO:0043226	organelle
1.37	2.02e-43	GO:0043227	membrane-bounded organelle
1.37	2.65e-43	GO:0043231	intracellular membrane-bounded organelle
1.54	6.37e-39	GO:0005634	nucleus
1.24	1.25e-37	GO:0044424	intracellular part
1.23	2.24e-37	GO:0005622	intracellular
1.48	1.98e-30	GO:0044446	intracellular organelle part
1.47	1.13e-29	GO:0044422	organelle part
1.91	4.61e-29	GO:0044428	nuclear part
1.79	1.19e-23	GO:0070013	intracellular organelle lumen
1.89	6.55e-23	GO:0031981	nuclear lumen
1.76	1.55e-22	GO:0043233	organelle lumen
1.75	2.34e-22	GO:0031974	membrane-enclosed lumen
2.03	6.43e-21	GO:0005654	nucleoplasm
2.51	1.17e-16	GO:0005694	chromosome
2.65	3.46e-16	GO:0044427	chromosomal part
3.36	1.74e-15	GO:0000785	chromatin
1.41	9.72e-12	GO:0032991	macromolecular complex
1.48	2.71e-11	GO:0043228	non-membrane-bounded organelle
1.48	2.71e-11	GO:0043232	intracellular non-membrane-bounded organelle
2.04	9.23e-11	GO:0044451	nucleoplasm part
3.78	7.05e-08	GO:0032993	protein-DNA complex
4.49	2.99e-07	GO:0000786	nucleosome
2.53	2.93e-06	GO:0016604	nuclear body
1.05	2.96e-06	GO:0044464	cell part
1.05	3.07e-06	GO:0005623	cell
1.15	1.07e-05	GO:0005737	cytoplasm
2.31	4.91e-05	GO:0005635	nuclear envelope
1.31	7.85e-05	GO:0043234	protein complex
2.23	1.19e-03	GO:0000228	nuclear chromosome
1.75	1.26e-03	GO:0030529	ribonucleoprotein complex
2.31	3.67e-03	GO:0044454	nuclear chromosome part
1.59	3.71e-03	GO:0031967	organelle envelope
1.58	4.13e-03	GO:0031975	envelope
2.34	1.06e-02	GO:0031965	nuclear membrane
2.38	1.58e-02	GO:0005681	spliceosomal complex
1.34	1.90e-02	GO:0012505	endomembrane system
2.30	2.02e-02	GO:0000775	chromosome, centromeric region
3.28	2.32e-02	GO:0034708	methyltransferase complex
3.28	2.32e-02	GO:0035097	histone methyltransferase complex
2.78	2.38e-02	GO:0000790	nuclear chromatin
2.38	3.05e-02	GO:0016607	nuclear speck
1.14	3.39e-02	GO:0044444	cytoplasmic part
3.45	4.64e-02	GO:0000792	heterochromatin
2.72	4.95e-02	GO:0071013	catalytic step 2 spliceosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	2.43e-16	GO:0005488	binding
1.51	4.29e-16	GO:0003676	nucleic acid binding
1.27	8.52e-16	GO:0005515	protein binding
1.53	4.66e-11	GO:0003677	DNA binding
1.45	1.30e-07	GO:0000166	nucleotide binding
1.39	2.08e-04	GO:0017076	purine nucleotide binding
1.39	3.35e-04	GO:0032553	ribonucleotide binding
1.39	3.35e-04	GO:0032555	purine ribonucleotide binding
1.43	3.74e-04	GO:0030554	adenyl nucleotide binding
1.43	4.22e-04	GO:0032559	adenyl ribonucleotide binding
1.38	6.00e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.60	8.30e-04	GO:0003723	RNA binding
1.42	1.04e-03	GO:0005524	ATP binding
3.89	1.84e-02	GO:0019205	nucleobase, nucleoside, nucleotide kinase activity
1.46	4.25e-02	GO:0016772	transferase activity, transferring phosphorus-containing groups