Motif ID: MAFB.p2

Z-value: 3.186


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAFBchr20_-_38751289-0.581.9e-02Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_157141565 4.434 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr5_+_139473873 4.301 NM_005859
 PURA
purine-rich element binding protein A
chr8_+_64243662 3.820 NM_152758
 YTHDF3
YTH domain family, member 3
chr15_+_94674849 3.775 NM_021005
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr17_+_31975611 3.731 GGNBP2
gametogenetin binding protein 2
chr3_-_88190737 3.471 NM_001008390
NM_003663
 CGGBP1

CGG triplet repeat binding protein 1

chr13_+_34414390 3.370 NM_015678
 NBEA
neurobeachin
chr15_+_36332258 3.239 NM_152594
 SPRED1
sprouty-related, EVH1 domain containing 1
chr8_+_64243741 3.146 YTHDF3
YTH domain family, member 3
chr10_+_93673485 3.025 BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
chr2_+_54537842 2.788 SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_-_62835601 2.778


chr14_+_31615959 2.736 ARHGAP5
Rho GTPase activating protein 5
chr6_+_163755658 2.716 NM_006775
NM_206853
NM_206854
NM_206855
 QKI



quaking homolog, KH domain RNA binding (mouse)



chr5_+_72179685 2.677 NM_153188
 TNPO1
transportin 1
chr3_+_112273352 2.670 PVRL3
poliovirus receptor-related 3
chr20_+_56899904 2.662 GNAS
GNAS complex locus
chr2_+_104838177 2.624 NM_006236
 POU3F3
POU class 3 homeobox 3
chr7_+_77005287 2.621 NM_001131008
NM_001131009
 PTPN12

protein tyrosine phosphatase, non-receptor type 12

chr14_+_31616196 2.544 NM_001030055
NM_001173
 ARHGAP5

Rho GTPase activating protein 5


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
1.80 2.23e-02 GO:0006470 protein dephosphorylation
1.76 2.14e-02 GO:0016311 dephosphorylation
1.43 2.37e-03 GO:0016071 mRNA metabolic process
1.39 3.00e-02 GO:0044265 cellular macromolecule catabolic process
1.38 1.89e-02 GO:0048666 neuron development
1.37 9.76e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.36 1.12e-02 GO:0010628 positive regulation of gene expression
1.35 2.09e-02 GO:0051254 positive regulation of RNA metabolic process
1.35 2.68e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 1.38e-04 GO:0006793 phosphorus metabolic process
1.34 1.38e-04 GO:0006796 phosphate metabolic process
1.34 1.30e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.33 2.00e-03 GO:0048468 cell development
1.33 1.49e-02 GO:0016192 vesicle-mediated transport
1.32 1.03e-08 GO:0006464 protein modification process
1.30 6.65e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.28 2.96e-07 GO:0043412 macromolecule modification
1.27 1.75e-09 GO:0044267 cellular protein metabolic process
1.27 3.24e-07 GO:0048523 negative regulation of cellular process
1.26 1.12e-03 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 20 entries
enrichment   p-value GO term description
1.34 1.70e-03 GO:0044451 nucleoplasm part
1.23 4.37e-03 GO:0005654 nucleoplasm
1.19 4.11e-06 GO:0043234 protein complex
1.18 5.02e-03 GO:0044428 nuclear part
1.17 4.20e-02 GO:0031981 nuclear lumen
1.16 4.67e-02 GO:0005829 cytosol
1.15 2.73e-08 GO:0005634 nucleus
1.14 7.65e-04 GO:0032991 macromolecular complex
1.11 5.52e-10 GO:0043231 intracellular membrane-bounded organelle
1.11 7.22e-10 GO:0043227 membrane-bounded organelle
1.11 2.68e-04 GO:0044446 intracellular organelle part
1.11 6.30e-04 GO:0044422 organelle part
1.10 2.01e-17 GO:0005622 intracellular
1.10 8.76e-17 GO:0044424 intracellular part
1.10 2.20e-10 GO:0043229 intracellular organelle
1.10 3.35e-10 GO:0043226 organelle
1.10 1.70e-07 GO:0005737 cytoplasm
1.10 2.44e-03 GO:0044444 cytoplasmic part
1.03 7.40e-04 GO:0044464 cell part
1.03 7.83e-04 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
3.36 1.33e-02 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
2.66 8.17e-03 GO:0005080 protein kinase C binding
1.69 9.97e-03 GO:0004721 phosphoprotein phosphatase activity
1.58 4.51e-02 GO:0003682 chromatin binding
1.49 1.32e-02 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.49 4.27e-02 GO:0016881 acid-amino acid ligase activity
1.41 6.08e-03 GO:0016874 ligase activity
1.36 3.05e-04 GO:0019899 enzyme binding
1.23 1.54e-03 GO:0032559 adenyl ribonucleotide binding
1.23 2.08e-03 GO:0030554 adenyl nucleotide binding
1.22 2.04e-04 GO:0032553 ribonucleotide binding
1.22 2.04e-04 GO:0032555 purine ribonucleotide binding
1.22 2.34e-04 GO:0017076 purine nucleotide binding
1.22 8.24e-03 GO:0005524 ATP binding
1.21 4.01e-05 GO:0000166 nucleotide binding
1.21 1.56e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.16 2.62e-17 GO:0005515 protein binding
1.07 7.32e-10 GO:0005488 binding