Motif ID: SOX5.p2

Z-value: 1.716


Transcription factors associated with SOX5.p2:

Gene SymbolEntrez IDGene Name
SOX5 6660 SRY (sex determining region Y)-box 5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX5chr12_-_239951090.783.9e-04Click!


Activity profile for motif SOX5.p2.

activity profile for motif SOX5.p2


Sorted Z-values histogram for motif SOX5.p2

Sorted Z-values for motif SOX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX5.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_16380967 3.627 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr7_-_11838260 3.244 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr4_+_42590038 3.005 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr3_+_174598937 2.124 NM_014932
NLGN1
neuroligin 1
chr4_-_101658094 2.099 NM_001159694
NM_016242
EMCN

endomucin

chr3_+_88270951 1.944 NM_018293
ZNF654
zinc finger protein 654
chr11_-_51269023 1.924 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr2_+_166137091 1.897 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr4_-_105635499 1.806 CXXC4
CXXC finger protein 4
chr12_-_11399776 1.805 NM_005039
NM_199353
NM_199354
PRB1


proline-rich protein BstNI subfamily 1


chr15_+_47502666 1.783 NM_002009
FGF7
fibroblast growth factor 7
chr3_-_121065112 1.778


chr10_+_96433240 1.713 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chrX_-_151370325 1.709 NM_000808
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr2_-_225073357 1.646 CUL3
cullin 3
chr1_-_51660328 1.616 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr20_-_21326046 1.614 NM_033176
NKX2-4
NK2 homeobox 4
chr11_-_121492010 1.602 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr9_-_85773899 1.584 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr10_+_49184658 1.576 MAPK8
mitogen-activated protein kinase 8
chr11_-_48330574 1.571 NM_001005513
OR4C45
olfactory receptor, family 4, subfamily C, member 45
chr11_+_101488380 1.557 NM_001195045
YAP1
Yes-associated protein 1
chr4_+_71096830 1.544 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr12_-_11354620 1.527 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr18_-_29412148 1.512


chr11_-_7684516 1.501 NM_198185
OVCH2
ovochymase 2 (gene/pseudogene)
chr1_+_198975227 1.497 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr2_-_55053398 1.446


chr15_+_22751162 1.412 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr14_-_105862080 1.383 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr4_+_110968594 1.365 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr8_+_104900591 1.354 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr3_+_89239494 1.354 EPHA3
EPH receptor A3
chr10_+_104525877 1.349 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr1_-_150564302 1.334 NM_002016
FLG
filaggrin
chr9_-_21375258 1.330 NM_000605
IFNA2
interferon, alpha 2
chr17_-_44058612 1.283 NM_024017
HOXB9
homeobox B9
chr17_+_3065661 1.274 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr15_-_23204887 1.249 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr9_+_108665168 1.248 NM_021224
ZNF462
zinc finger protein 462
chr11_-_55460451 1.206 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr9_+_102244005 1.201 NM_001198812
C9orf3-TMEFF1
C9orf30
C9orf3-TMEFF1 readthrough
chromosome 9 open reading frame 30
chr21_-_30583702 1.199 NM_001128598
KRTAP25-1
keratin associated protein 25-1
chr3_+_89239363 1.198 NM_005233
NM_182644
EPHA3

EPH receptor A3

chr5_-_111340421 1.188 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr1_-_7998265 1.173 ERRFI1
ERBB receptor feedback inhibitor 1
chr10_-_98311813 1.172 TM9SF3
transmembrane 9 superfamily member 3
chr2_-_63518589 1.166 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chrX_+_55951280 1.164


chr12_-_23995109 1.162 SOX5
SRY (sex determining region Y)-box 5
chr6_+_105511615 1.157 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr12_-_23995220 1.153 SOX5
SRY (sex determining region Y)-box 5
chr10_-_98280299 1.141 TM9SF3
transmembrane 9 superfamily member 3
chr7_-_86526880 1.136 NM_001142749
KIAA1324L
KIAA1324-like
chr2_-_39310176 1.093 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr12_-_89976261 1.093 NM_007035
KERA
keratocan
chr5_-_147266257 1.090 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr3_+_99350859 1.082 NM_001005514
OR5H14
olfactory receptor, family 5, subfamily H, member 14
chr7_-_22518200 1.081 EEF1A1
eukaryotic translation elongation factor 1 alpha 1
chr6_+_88026338 1.081 ZNF292
zinc finger protein 292
chr3_-_18455207 1.074 NM_001131010
SATB1
SATB homeobox 1
chr12_-_97812633 1.073 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_-_108914277 1.044 NM_001013031
NM_052918
SORCS1

sortilin-related VPS10 domain containing receptor 1

chr3_-_56673113 1.042 NM_015224
C3orf63
chromosome 3 open reading frame 63
chr3_+_85858321 1.041 NM_153184
CADM2
cell adhesion molecule 2
chr1_+_116727514 1.040 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chrX_-_39921525 1.035 NM_001123383
NM_001123384
BCOR

BCL6 corepressor

chr15_+_100175888 1.030 NM_001001674
OR4F15
olfactory receptor, family 4, subfamily F, member 15
chr3_+_173954940 1.020 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr21_-_31049566 1.020 NM_181619
KRTAP21-1
keratin associated protein 21-1
chr2_+_211166323 1.018 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr14_-_106184988 1.016 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_28709302 1.012 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr12_+_68028397 1.007 NM_000239
LYZ
lysozyme
chr1_+_145479805 1.000 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr16_+_65938753 0.994 NM_001161575
LRRC36
leucine rich repeat containing 36
chr6_-_46155937 0.992 NM_001114086
CLIC5
chloride intracellular channel 5
chr4_-_113656762 0.980 NM_024019
NEUROG2
neurogenin 2
chr14_-_54948290 0.980 NM_014924
ATG14
ATG14 autophagy related 14 homolog (S. cerevisiae)
chr6_+_154373323 0.974 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chr1_-_150353179 0.972 NM_007113
TCHH
trichohyalin
chr2_-_55090759 0.970 NM_007008
RTN4
reticulon 4
chr1_-_49014993 0.967 NM_024603
BEND5
BEN domain containing 5
chr2_+_167468220 0.958 NM_001079810
NM_152381
XIRP2

xin actin-binding repeat containing 2

chr1_-_214963279 0.957 NM_001438
ESRRG
estrogen-related receptor gamma
chr8_-_125785611 0.948 MTSS1
metastasis suppressor 1
chr6_-_128263868 0.948 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr10_-_62002672 0.922 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr12_+_26017954 0.921 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_+_183281173 0.920 NM_007212
RNF2
ring finger protein 2
chr14_-_22974707 0.916 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr3_-_113701073 0.903 NM_001085357
NM_181780
BTLA

B and T lymphocyte associated

chr20_+_20296744 0.897 NM_002196
INSM1
insulinoma-associated 1
chr11_+_5925152 0.894 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr5_+_147754467 0.893 FBXO38
F-box protein 38
chr11_+_54891935 0.891 NM_001005275
OR4A15
olfactory receptor, family 4, subfamily A, member 15
chr20_+_23293020 0.889 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr10_+_24537725 0.889 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr17_-_36451189 0.885 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr11_+_55799604 0.884 NM_001004745
OR5T1
olfactory receptor, family 5, subfamily T, member 1
chr2_+_62787534 0.878 NM_001142614
EHBP1
EH domain binding protein 1
chr4_+_114190233 0.877 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr11_+_33236435 0.874 HIPK3
homeodomain interacting protein kinase 3
chrX_-_83644054 0.871 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr12_+_68028407 0.859 LYZ
lysozyme
chr20_+_71230 0.857 NM_030931
DEFB126
defensin, beta 126
chr16_+_68284252 0.854 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr12_-_11066436 0.854 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr11_+_55842358 0.852 NM_001005202
OR8K3
olfactory receptor, family 8, subfamily K, member 3
chr11_-_123353607 0.848 NM_001004474
OR10S1
olfactory receptor, family 10, subfamily S, member 1
chr16_+_55373241 0.845 NUP93
nucleoporin 93kDa
chr4_-_20594645 0.844 KCNIP4
Kv channel interacting protein 4
chr3_-_130373241 0.840 CNBP
CCHC-type zinc finger, nucleic acid binding protein
chr7_+_93373755 0.839 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr3_+_150028130 0.837 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr8_+_103633023 0.833 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr10_-_98263434 0.829 NM_012465
TLL2
tolloid-like 2
chr8_-_72437020 0.823 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr11_+_5862076 0.823 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr10_+_97749837 0.822 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr20_+_2892918 0.819 PTPRA
protein tyrosine phosphatase, receptor type, A
chr4_-_83566045 0.808


chr3_-_69212192 0.799 NM_003968
NM_198195
UBA3

ubiquitin-like modifier activating enzyme 3

chr8_-_93144366 0.798 NM_004349
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_178977441 0.795 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr22_-_39189369 0.794 MKL1
megakaryoblastic leukemia (translocation) 1
chr2_-_128138435 0.784 NM_017980
LIMS2
LIM and senescent cell antigen-like domains 2
chr10_-_56230953 0.773 NM_001142763
NM_001142764
NM_001142765
NM_001142766
NM_001142767
NM_001142768
NM_001142769
NM_001142770
NM_001142771
NM_001142772
NM_001142773
NM_033056
PCDH15











protocadherin-related 15











chr3_-_62835601 0.771


chr1_+_81544432 0.770 LPHN2
latrophilin 2
chr9_-_72673753 0.770 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr12_-_66905802 0.762 NM_018402
IL26
interleukin 26
chr8_+_74369647 0.761 NM_172037
RDH10
retinol dehydrogenase 10 (all-trans)
chr12_-_11041740 0.760 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr15_+_71953020 0.751 NM_153356
TBC1D21
TBC1 domain family, member 21
chr11_+_22652957 0.749 GAS2
growth arrest-specific 2
chr10_-_74863303 0.748 NM_001024593
ZMYND17
zinc finger, MYND-type containing 17
chr11_-_92570626 0.745


chr3_-_47909001 0.741 MAP4
microtubule-associated protein 4
chr10_+_86121526 0.741 FAM190B
family with sequence similarity 190, member B
chr1_-_246804680 0.741 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr2_+_228386800 0.740 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr3_+_162697289 0.740 NM_001080440
OTOL1
otolin 1 homolog (zebrafish)
chr2_-_208697441 0.738 NM_006891
CRYGD
crystallin, gamma D
chr4_+_53975597 0.737 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr7_-_82630063 0.735 NM_014510
NM_033026
PCLO

piccolo (presynaptic cytomatrix protein)

chr6_+_89847183 0.734 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_-_128883125 0.733 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_-_18134319 0.732 NM_024730
RERGL
RERG/RAS-like
chr5_+_102493155 0.731 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr2_-_164300758 0.729 NM_018086
FIGN
fidgetin
chr10_+_118295417 0.727 NM_000936
PNLIP
pancreatic lipase
chr11_+_36274300 0.723 NM_001160167
PRR5L
proline rich 5 like
chr17_-_3248453 0.721 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr5_-_146441184 0.721 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr2_+_191009265 0.720 MFSD6
major facilitator superfamily domain containing 6
chr14_-_94669547 0.715 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr15_+_37660568 0.712 NM_003246
THBS1
thrombospondin 1
chr8_+_87947788 0.712 NM_173538
CNBD1
cyclic nucleotide binding domain containing 1
chr14_-_91483757 0.711 NM_006329
FBLN5
fibulin 5
chrX_-_32340291 0.705 NM_004011
NM_004012
DMD

dystrophin

chr15_+_36331411 0.705 SPRED1
sprouty-related, EVH1 domain containing 1
chr10_+_129237602 0.702 NM_001030013
NPS
neuropeptide S
chr11_-_27637771 0.695 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr14_+_19414230 0.694 NM_001005501
OR4K2
olfactory receptor, family 4, subfamily K, member 2
chr12_+_21417068 0.688 NM_000415
IAPP
islet amyloid polypeptide
chr18_-_55136673 0.686 NM_181654
CPLX4
complexin 4
chr3_-_66634031 0.683 LRIG1
leucine-rich repeats and immunoglobulin-like domains 1
chrX_-_111970662 0.681 NM_133265
AMOT
angiomotin
chr18_+_29412538 0.680 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr12_-_85756766 0.679 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr13_+_81162030 0.679


chr16_+_21518633 0.678 METTL9
methyltransferase like 9
chr14_-_70345485 0.678 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr1_+_148603769 0.677 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr12_+_54132264 0.677 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr9_-_4142182 0.676 NM_152629
GLIS3
GLIS family zinc finger 3
chr2_+_108230082 0.674 NM_001008743
SULT1C3
sulfotransferase family, cytosolic, 1C, member 3
chr3_-_101077605 0.673 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr3_+_112743615 0.672 NM_005816
NM_198196
CD96

CD96 molecule

chr7_-_116854765 0.671 NM_130768
ASZ1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr13_+_51933228 0.670 CKAP2
cytoskeleton associated protein 2
chr4_+_71235259 0.668 NM_033122
CABS1
calcium-binding protein, spermatid-specific 1
chr2_-_215953818 0.667 FN1
fibronectin 1
chr1_-_90955365 0.665 NM_020063
BARHL2
BarH-like homeobox 2
chr17_+_59244363 0.662 DDX42
DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr17_-_36074812 0.658 NM_152349
KRT222
keratin 222
chr2_-_180319013 0.657 NM_001113397
ZNF385B
zinc finger protein 385B
chr3_-_121117647 0.656 GSK3B
glycogen synthase kinase 3 beta
chr4_-_64957595 0.655 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr3_+_189425886 0.654 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_+_74473672 0.653 NM_015978
TNNI3K
TNNI3 interacting kinase
chr6_-_127882192 0.651 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr12_-_98072602 0.646 NM_020140
NM_181670
ANKS1B

ankyrin repeat and sterile alpha motif domain containing 1B

chr9_+_106371269 0.645 NM_001004483
OR13C8
olfactory receptor, family 13, subfamily C, member 8
chr1_-_202730135 0.638 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr10_+_115514567 0.636 NM_182601
C10orf81
chromosome 10 open reading frame 81
chr7_-_122126422 0.635 NM_139175
RNF133
ring finger protein 133
chr3_+_112743729 0.632 CD96
CD96 molecule
chr9_-_40782062 0.630 NM_033160
ZNF658
zinc finger protein 658

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.55 3.76e-16 GO:0007608 sensory perception of smell
2.40 7.42e-15 GO:0007606 sensory perception of chemical stimulus
1.83 9.34e-10 GO:0007600 sensory perception
1.56 1.14e-07 GO:0050877 neurological system process
1.47 6.47e-07 GO:0003008 system process
1.16 1.03e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 3.97e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.60 8.23e-17 GO:0004984 olfactory receptor activity
1.69 2.29e-07 GO:0004930 G-protein coupled receptor activity
1.42 4.91e-04 GO:0004888 transmembrane receptor activity
1.31 9.62e-03 GO:0004872 receptor activity
1.26 2.86e-02 GO:0004871 signal transducer activity
1.26 2.86e-02 GO:0060089 molecular transducer activity