Motif ID: TFCP2.p2

Z-value: 3.638


Transcription factors associated with TFCP2.p2:

Gene SymbolEntrez IDGene Name
TFCP2 7024 transcription factor CP2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFCP2chr12_-_498528220.302.6e-01Click!


Activity profile for motif TFCP2.p2.

activity profile for motif TFCP2.p2


Sorted Z-values histogram for motif TFCP2.p2

Sorted Z-values for motif TFCP2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFCP2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_1465602 4.960 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr9_-_138234707 4.813 NM_014564
LHX3
LIM homeobox 3
chr19_-_1827133 3.180


chr11_+_65100074 3.134 NM_001099409
EHBP1L1
EH domain binding protein 1-like 1
chr20_-_30636535 2.985 LOC284804
hypothetical protein LOC284804
chr7_+_1239078 2.983 NM_001080461
UNCX
UNC homeobox
chr17_-_959007 2.957 NM_001092
ABR
active BCR-related gene
chr17_-_75427644 2.950 NM_003655
CBX4
chromobox homolog 4
chr19_-_13808101 2.930 LOC284454
hypothetical LOC284454
chr19_-_11390948 2.869 NM_001035223
NM_001161616
RGL3

ral guanine nucleotide dissociation stimulator-like 3

chr16_-_2099854 2.846 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr12_+_47658502 2.831 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr13_+_112681626 2.704 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr11_+_627268 2.702 NM_000797
DRD4
dopamine receptor D4
chr1_+_2397613 2.626 NM_014638
PLCH2
phospholipase C, eta 2
chr17_+_1129706 2.619 NM_172367
TUSC5
tumor suppressor candidate 5
chr2_+_238712101 2.578 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr16_+_705080 2.469 NM_024042
METRN
meteorin, glial cell differentiation regulator
chr19_+_2427122 2.369 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr5_+_170668892 2.360 NM_021025
TLX3
T-cell leukemia homeobox 3
chr7_-_1946667 2.325 MAD1L1
MAD1 mitotic arrest deficient-like 1 (yeast)
chr20_+_61337679 2.322 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr1_-_1171964 2.301 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr22_+_48971067 2.285 TRABD
TraB domain containing
chr9_+_139091759 2.270 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr11_+_67567022 2.252 NM_006053
TCIRG1
T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3
chr16_+_11669736 2.193 NM_003498
SNN
stannin
chr1_-_226202210 2.179 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr17_+_4434582 2.178 NM_001114974
SMTNL2
smoothelin-like 2
chr19_+_3129735 2.168 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chr17_+_21128614 2.160 MAP2K3
mitogen-activated protein kinase kinase 3
chr14_-_104515738 2.120 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr10_-_88116181 2.094 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr15_+_66658626 2.094 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr17_+_75849221 2.070 NM_020914
NM_020954
RNF213

ring finger protein 213

chr11_+_63883192 2.057 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr3_+_185515108 2.052 EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr12_+_52680143 2.052 NM_006897
HOXC9
homeobox C9
chr7_-_44331544 2.037 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr11_+_183079 2.027 NM_145651
SCGB1C1
secretoglobin, family 1C, member 1
chr1_+_36394044 2.025 MAP7D1
MAP7 domain containing 1
chr7_+_128257698 2.024 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr4_+_8322358 2.002 NM_053044
HTRA3
HtrA serine peptidase 3
chr1_+_1256585 1.983 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr20_-_61669550 1.969 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr22_-_49050847 1.949 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr19_-_60587414 1.921 NM_001190764
LOC388564
hypothetical protein LOC388564
chr20_-_60484420 1.902 NM_080473
GATA5
GATA binding protein 5
chr1_+_152806924 1.901 CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr1_+_1557419 1.895 NM_006983
MMP23B
matrix metallopeptidase 23B
chr11_+_76455574 1.891 NM_004055
CAPN5
calpain 5
chr10_-_104158910 1.841 PSD
pleckstrin and Sec7 domain containing
chr9_+_100609754 1.818 NM_024642
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr12_+_112071930 1.772 NM_001144872
CCDC42B
coiled-coil domain containing 42B
chr14_+_104402626 1.766 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr9_-_137531517 1.764 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr1_-_1131795 1.756 NM_004195
NM_148901
NM_148902
TNFRSF18


tumor necrosis factor receptor superfamily, member 18


chr1_+_152806874 1.752 NM_000748
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr17_+_21128560 1.738 NM_145109
MAP2K3
mitogen-activated protein kinase kinase 3
chr8_+_144751216 1.737 NM_032862
TIGD5
tigger transposable element derived 5
chr22_+_34267297 1.736 NM_014310
RASD2
RASD family, member 2
chr2_+_26249463 1.732 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr10_+_102495327 1.730 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr22_+_34266837 1.712


chr22_-_37569679 1.708


chr13_-_49597776 1.702 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr17_+_56832255 1.689 TBX2
T-box 2
chr20_-_60415729 1.683 NM_031215
CABLES2
Cdk5 and Abl enzyme substrate 2
chr17_+_30498948 1.680 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr11_-_64327197 1.668 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr19_+_482688 1.660 NM_004359
CDC34
cell division cycle 34 homolog (S. cerevisiae)
chr17_+_75507750 1.653


chr17_-_17340219 1.642 NM_016084
RASD1
RAS, dexamethasone-induced 1
chr11_+_63775567 1.631 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr8_-_139995417 1.621 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr1_-_110950497 1.616 KCNA2
potassium voltage-gated channel, shaker-related subfamily, member 2
chr20_-_61933012 1.610 ZBTB46
zinc finger and BTB domain containing 46
chr1_-_16355013 1.608 NM_004431
EPHA2
EPH receptor A2
chr21_+_44566063 1.604 PFKL
phosphofructokinase, liver
chr19_-_2187648 1.597 PLEKHJ1
pleckstrin homology domain containing, family J member 1
chr19_+_17923110 1.588 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr9_+_139092016 1.588 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr22_-_49063088 1.577 PLXNB2
plexin B2
chr11_+_76491532 1.576 NM_006189
OMP
olfactory marker protein
chr3_+_46717826 1.571 NM_147196
TMIE
transmembrane inner ear
chr11_+_1848674 1.570 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr1_+_226462363 1.565 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr9_+_131974506 1.555 NM_014286
NCS1
neuronal calcium sensor 1
chr9_+_139265533 1.555 NM_001004353
C9orf173
chromosome 9 open reading frame 173
chr7_-_1034453 1.537 C7orf50
chromosome 7 open reading frame 50
chr16_+_3036682 1.535 NM_022468
MMP25
matrix metallopeptidase 25
chr9_+_139006663 1.534 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr8_-_145099963 1.532 NM_201379
PLEC
plectin
chr17_+_21128625 1.526 MAP2K3
mitogen-activated protein kinase kinase 3
chr11_-_1464386 1.523 NM_001172223
MOB2
Mps one binder kinase activator-like 2
chr21_+_46226072 1.521 NM_001848
COL6A1
collagen, type VI, alpha 1
chr10_-_125641484 1.519 NM_198148
CPXM2
carboxypeptidase X (M14 family), member 2
chr20_-_26137755 1.513 LOC284801
hypothetical protein LOC284801
chrX_+_150614385 1.508 NM_024082
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr7_-_100331417 1.505 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr1_+_226741665 1.493 NM_001010858
RNF187
ring finger protein 187
chr15_+_29406335 1.489 NM_015995
KLF13
Kruppel-like factor 13
chr9_+_36126710 1.486 NM_022343
GLIPR2
GLI pathogenesis-related 2
chr12_-_51585004 1.483 NM_002273
KRT8
keratin 8
chr9_-_95757448 1.472 BARX1
BARX homeobox 1
chr2_+_219991342 1.466 NM_001927
DES
desmin
chr17_-_45562112 1.463 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr16_+_1949517 1.463 NM_004548
NDUFB10
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10, 22kDa
chr11_+_65802221 1.461 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr19_+_2187815 1.452 NM_007165
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr9_-_139184247 1.443 NM_001013653
LRRC26
leucine rich repeat containing 26
chr17_+_24095135 1.440 NM_004295
TRAF4
TNF receptor-associated factor 4
chr11_+_64838882 1.414 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr2_+_241023908 1.413 GPC1
glypican 1
chr19_+_482737 1.408 CDC34
cell division cycle 34 homolog (S. cerevisiae)
chrX_+_153339814 1.407 NM_017514
PLXNA3
plexin A3
chr19_+_54872304 1.402 NM_001536
NM_198318
PRMT1

protein arginine methyltransferase 1

chr19_+_40824486 1.402 NM_014209
ETV2
ets variant 2
chr10_+_124210980 1.398 NM_002775
HTRA1
HtrA serine peptidase 1
chr11_-_2136129 1.391


chr22_-_37569962 1.391 NM_014293
NPTXR
neuronal pentraxin receptor
chr11_-_62539857 1.389 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr9_+_36126667 1.387 GLIPR2
GLI pathogenesis-related 2
chr15_-_26017994 1.370 NM_000275
OCA2
oculocutaneous albinism II
chr14_-_99842519 1.370 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr16_+_670420 1.369 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr9_-_95757365 1.366 NM_021570
BARX1
BARX homeobox 1
chr19_+_54872220 1.362 PRMT1
protein arginine methyltransferase 1
chr11_-_407324 1.361 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_-_50429306 1.361 NM_138568
EXOC3L2
exocyst complex component 3-like 2
chr8_+_145718702 1.356


chr9_+_125813849 1.352 LHX2
LIM homeobox 2
chr17_+_56831951 1.348 NM_005994
TBX2
T-box 2
chr1_+_154478574 1.345 NM_199173
BGLAP
bone gamma-carboxyglutamate (gla) protein
chr9_+_137107007 1.342 OLFM1
olfactomedin 1
chr19_+_590878 1.339 NM_020637
FGF22
fibroblast growth factor 22
chr16_-_2521359 1.336 NM_001048212
CEMP1
cementum protein 1
chr2_+_232951487 1.333 NM_001632
ALPP
alkaline phosphatase, placental
chr2_+_71016503 1.323 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr22_-_39964001 1.320 CHADL
chondroadherin-like
chr9_+_137107187 1.317 OLFM1
olfactomedin 1
chr9_+_137106909 1.316 NM_014279
NM_006334
OLFM1

olfactomedin 1

chr16_+_670426 1.313 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr4_+_4912272 1.308 NM_002448
MSX1
msh homeobox 1
chr2_-_128792515 1.305 NM_004807
HS6ST1
heparan sulfate 6-O-sulfotransferase 1
chr16_+_2226468 1.296 NM_001374
DNASE1L2
deoxyribonuclease I-like 2
chr9_+_91409746 1.290 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr17_+_72982919 1.288 NM_001113495
SEPT9
septin 9
chr19_-_63550712 1.287 A1BG
alpha-1-B glycoprotein
chr1_+_1099145 1.280 NM_001130045
TTLL10
tubulin tyrosine ligase-like family, member 10
chr2_+_241023703 1.279 NM_002081
GPC1
glypican 1
chr8_+_145705253 1.277 NM_138431
MFSD3
major facilitator superfamily domain containing 3
chr16_+_670389 1.273 STUB1
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
chr9_+_137107088 1.273 OLFM1
olfactomedin 1
chr1_-_25129354 1.267 NM_004350
RUNX3
runt-related transcription factor 3
chr10_+_133850325 1.266 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr1_+_36394338 1.266 NM_018067
MAP7D1
MAP7 domain containing 1
chr1_-_25129305 1.266 RUNX3
runt-related transcription factor 3
chr6_+_150326802 1.264 NM_025218
ULBP1
UL16 binding protein 1
chr11_-_785005 1.257 SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr19_+_60816770 1.250 NM_001195605
ZNF865
zinc finger protein 865
chrX_+_128942435 1.242


chr20_-_62151216 1.241 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr10_+_112247614 1.241 NM_004419
DUSP5
dual specificity phosphatase 5
chr22_-_22252376 1.240 NM_020070
NM_152855
IGLL1

immunoglobulin lambda-like polypeptide 1

chr19_-_19615369 1.240 GMIP
GEM interacting protein
chr17_+_56832492 1.237 TBX2
T-box 2
chr14_+_102659464 1.233 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr10_+_104145421 1.230 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_+_55399847 1.225 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr1_+_200124412 1.223 NM_198149
SHISA4
shisa homolog 4 (Xenopus laevis)
chr10_-_99521701 1.222 NM_003015
SFRP5
secreted frizzled-related protein 5
chr17_+_7225088 1.222 NM_003985
TNK1
tyrosine kinase, non-receptor, 1
chr19_+_1397268 1.220 APC2
adenomatosis polyposis coli 2
chr1_+_39229474 1.208 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr17_+_38250122 1.204 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr1_+_968522 1.203 AGRN
agrin
chr16_+_1323627 1.203 BAIAP3
BAI1-associated protein 3
chr19_-_19615452 1.202 NM_016573
GMIP
GEM interacting protein
chr16_+_2593351 1.196 LOC652276
hypothetical LOC652276
chr11_+_46339691 1.196 NM_001105540
DGKZ
diacylglycerol kinase, zeta
chr16_-_87646856 1.194


chr2_-_27339278 1.193 NM_003459
SLC30A3
solute carrier family 30 (zinc transporter), member 3
chr8_-_144969529 1.192 NM_015356
NM_182706
SCRIB

scribbled homolog (Drosophila)

chr10_+_134901397 1.187 NM_014468
VENTX
VENT homeobox homolog (Xenopus laevis)
chr1_+_39729885 1.185 NM_181809
BMP8A
bone morphogenetic protein 8a
chr11_+_35117408 1.173 CD44
CD44 molecule (Indian blood group)
chr11_+_2355099 1.173 CD81
CD81 molecule
chr17_-_42250961 1.168 NM_030753
WNT3
wingless-type MMTV integration site family, member 3
chr17_-_60208083 1.167 LOC146880
hypothetical LOC146880
chr19_-_7896974 1.162 NM_206833
CTXN1
cortexin 1
chr16_-_88314762 1.161 NM_004913
C16orf7
chromosome 16 open reading frame 7
chr16_+_82559600 1.159 NM_019065
NECAB2
N-terminal EF-hand calcium binding protein 2
chr4_+_7096043 1.159 NM_152293
TADA2B
transcriptional adaptor 2B
chr10_+_6284845 1.156 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr9_+_137107222 1.154 OLFM1
olfactomedin 1
chr9_-_35062643 1.149 NM_007126
VCP
valosin containing protein
chr20_+_60311443 1.148 ADRM1
adhesion regulating molecule 1
chr11_+_35117391 1.148 CD44
CD44 molecule (Indian blood group)
chr20_+_60311334 1.148 ADRM1
adhesion regulating molecule 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.14 3.23e-10 GO:0065007 biological regulation
1.13 4.59e-08 GO:0050789 regulation of biological process
1.13 2.40e-07 GO:0050794 regulation of cellular process
1.24 2.56e-07 GO:0048731 system development
1.45 3.81e-07 GO:0042127 regulation of cell proliferation
1.20 4.82e-07 GO:0023052 signaling
1.28 2.11e-06 GO:0030154 cell differentiation
1.25 3.46e-06 GO:0048519 negative regulation of biological process
1.20 4.76e-06 GO:0007275 multicellular organismal development
1.33 6.09e-06 GO:0007399 nervous system development
1.21 7.08e-06 GO:0048856 anatomical structure development
1.26 8.15e-06 GO:0048523 negative regulation of cellular process
1.31 8.63e-06 GO:0023051 regulation of signaling
1.26 1.08e-05 GO:0048869 cellular developmental process
1.28 1.53e-05 GO:0048583 regulation of response to stimulus
1.32 1.82e-05 GO:0009966 regulation of signal transduction
1.33 3.69e-05 GO:0051239 regulation of multicellular organismal process
1.17 6.72e-05 GO:0032502 developmental process
1.26 8.31e-05 GO:0048513 organ development
1.38 1.67e-04 GO:0050793 regulation of developmental process
1.18 2.21e-04 GO:0007165 signal transduction
1.23 2.78e-04 GO:0042221 response to chemical stimulus
1.20 3.44e-04 GO:0048518 positive regulation of biological process
1.23 4.53e-04 GO:0065008 regulation of biological quality
1.66 1.02e-03 GO:0051270 regulation of cellular component movement
1.54 1.17e-03 GO:0008285 negative regulation of cell proliferation
1.25 1.28e-03 GO:0007166 cell surface receptor linked signaling pathway
1.36 1.40e-03 GO:0022008 neurogenesis
1.20 1.49e-03 GO:0048522 positive regulation of cellular process
1.65 1.73e-03 GO:0040012 regulation of locomotion
1.68 2.05e-03 GO:0030334 regulation of cell migration
1.36 2.25e-03 GO:0048699 generation of neurons
1.38 2.96e-03 GO:2000026 regulation of multicellular organismal development
1.66 3.61e-03 GO:2000145 regulation of cell motility
1.39 5.29e-03 GO:0030182 neuron differentiation
1.45 7.56e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.61 1.09e-02 GO:0051960 regulation of nervous system development
1.05 1.86e-02 GO:0009987 cellular process
1.13 2.06e-02 GO:0051716 cellular response to stimulus
1.48 2.10e-02 GO:0040008 regulation of growth
1.31 2.50e-02 GO:0048468 cell development
1.49 2.64e-02 GO:0007264 small GTPase mediated signal transduction
1.36 2.86e-02 GO:0009790 embryo development
1.43 2.91e-02 GO:0000904 cell morphogenesis involved in differentiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.17 2.04e-02 GO:0044459 plasma membrane part
1.25 3.74e-02 GO:0044421 extracellular region part

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 2.69e-04 GO:0005515 protein binding
1.29 6.20e-03 GO:0001071 nucleic acid binding transcription factor activity
1.29 6.20e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.27 2.23e-02 GO:0005102 receptor binding
1.27 2.58e-02 GO:0030528 transcription regulator activity
1.32 3.75e-02 GO:0043565 sequence-specific DNA binding