Motif ID: NRF1.p2

Z-value: 5.389


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290388150.792.6e-04Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_254742 6.373 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chr20_+_48781457 6.043 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr2_+_254843 5.374 NM_001040649
NM_004300
NM_007099
ACP1


acid phosphatase 1, soluble


chr2_+_118562499 5.080 NM_016133
INSIG2
insulin induced gene 2
chr12_+_105873803 4.864 C12orf23
chromosome 12 open reading frame 23
chr1_+_227473638 4.741 RAB4A
RAB4A, member RAS oncogene family
chr2_+_28828112 4.537 NM_206876
NM_002709
PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr12_+_105873669 4.450 NM_152261
C12orf23
chromosome 12 open reading frame 23
chr6_+_41148869 4.266 NFYA
nuclear transcription factor Y, alpha
chr15_+_22751162 4.240 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr5_+_52131686 4.131 PELO
pelota homolog (Drosophila)
chr9_+_109085337 4.129 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr14_+_22633728 4.108 C14orf119
chromosome 14 open reading frame 119
chr1_+_227473458 4.018 NM_004578
RAB4A
RAB4A, member RAS oncogene family
chr9_+_109085372 3.993 RAD23B
RAD23 homolog B (S. cerevisiae)
chr21_+_33619147 3.830 IFNAR1
interferon (alpha, beta and omega) receptor 1
chr9_+_109085386 3.810 RAD23B
RAD23 homolog B (S. cerevisiae)
chr2_+_71412348 3.717 NM_001014972
NM_014497
ZNF638

zinc finger protein 638

chr5_+_72287625 3.703


chr20_+_39091026 3.660 TOP1
topoisomerase (DNA) I
chr5_+_271355 3.621 NM_004168
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr5_+_271447 3.616 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr3_+_73128771 3.541 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr20_+_11819364 3.514 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr20_+_39090875 3.492 NM_003286
TOP1
topoisomerase (DNA) I
chr5_+_271428 3.490 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr5_-_271235 3.489 NM_145265
CCDC127
coiled-coil domain containing 127
chr2_+_42249896 3.417 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr5_+_271441 3.403 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr6_-_163754903 3.385 LOC100526820
hypothetical LOC100526820
chr4_+_6726555 3.368 LOC93622
hypothetical LOC93622
chr3_+_73128629 3.362 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr3_+_43303005 3.361 NM_001100594
NM_017719
SNRK

SNF related kinase

chr1_+_165456572 3.309 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr3_+_73128667 3.238 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr21_+_46880017 3.235 PRMT2
protein arginine methyltransferase 2
chr3_+_139388770 3.230 NM_014154
NM_015396
NM_213654
ARMC8


armadillo repeat containing 8


chr21_+_46879954 3.196 NM_001535
NM_206962
PRMT2

protein arginine methyltransferase 2

chr20_+_25124333 3.127 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr2_+_86521781 3.107 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr5_+_72287630 3.061 FCHO2
FCH domain only 2
chr6_+_44463265 3.049 NM_001253
CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr21_+_46880013 3.037 PRMT2
protein arginine methyltransferase 2
chr15_+_39739864 3.031 NM_001080541
NM_001164273
MGA

MAX gene associated

chr3_-_151803639 3.015 SERP1
stress-associated endoplasmic reticulum protein 1
chr11_+_66643311 3.001 NM_012308
KDM2A
lysine (K)-specific demethylase 2A
chr12_-_52960168 2.972 NM_012117
CBX5
chromobox homolog 5
chr6_+_44463418 2.960 CDC5L
CDC5 cell division cycle 5-like (S. pombe)
chr16_+_83291107 2.948 USP10
ubiquitin specific peptidase 10
chr3_+_151803755 2.938 NM_016275
SELT
selenoprotein T
chr16_+_83291055 2.900 NM_005153
USP10
ubiquitin specific peptidase 10
chr5_+_72287509 2.894 NM_001146032
NM_138782
FCHO2

FCH domain only 2

chr16_+_83291097 2.891 USP10
ubiquitin specific peptidase 10
chr21_+_37367432 2.864 NM_001001894
TTC3
tetratricopeptide repeat domain 3
chr12_-_52960146 2.807 CBX5
chromobox homolog 5
chr15_+_39739933 2.799 MGA
MAX gene associated
chr16_+_83291112 2.794 USP10
ubiquitin specific peptidase 10
chr2_+_196230096 2.770 NM_020342
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr10_+_59698891 2.770 NM_018464
CISD1
CDGSH iron sulfur domain 1
chr14_-_22634134 2.721 ACIN1
apoptotic chromatin condensation inducer 1
chr1_+_35507197 2.696 ZMYM4
zinc finger, MYM-type 4
chr6_+_41148691 2.695 NFYA
nuclear transcription factor Y, alpha
chr5_+_112340326 2.683 NM_152624
DCP2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr21_+_33619067 2.683 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr1_+_148603208 2.661 RPRD2
regulation of nuclear pre-mRNA domain containing 2
chr2_+_138975946 2.660


chr3_+_196870122 2.657 SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr8_+_28407613 2.636 NM_017412
FZD3
frizzled homolog 3 (Drosophila)
chr9_+_109085643 2.618 RAD23B
RAD23 homolog B (S. cerevisiae)
chr12_-_123023052 2.617 NM_025140
CCDC92
coiled-coil domain containing 92
chr12_-_52960206 2.587 CBX5
chromobox homolog 5
chr12_-_123023312 2.550 CCDC92
coiled-coil domain containing 92
chr5_+_138706029 2.533 NM_001033112
PAIP2
poly(A) binding protein interacting protein 2
chr2_+_86186815 2.486 NM_017952
PTCD3
Pentatricopeptide repeat domain 3
chr9_+_113433364 2.482 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr2_+_69910424 2.476 GMCL1
germ cell-less homolog 1 (Drosophila)
chr16_+_73739890 2.472 NM_153688
ZFP1
zinc finger protein 1 homolog (mouse)
chr17_+_32924090 2.471 DUSP14
dual specificity phosphatase 14
chr20_+_55359706 2.469 RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr12_+_129922510 2.443 NM_006325
RAN
RAN, member RAS oncogene family
chr2_+_98427737 2.443 NM_001134224
NM_001134225
NM_001566
NM_004027
INPP4A



inositol polyphosphate-4-phosphatase, type I, 107kDa



chr17_+_55325224 2.433 NM_003161
RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr6_-_41148061 2.431 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr9_+_70584739 2.427 NM_138333
FAM122A
family with sequence similarity 122A
chr16_+_14634168 2.404 NM_016561
BFAR
bifunctional apoptosis regulator
chr12_+_123023521 2.397 NM_152437
ZNF664
zinc finger protein 664
chr17_+_32924049 2.395 NM_007026
DUSP14
dual specificity phosphatase 14
chr2_-_86186788 2.378 NM_015425
POLR1A
polymerase (RNA) I polypeptide A, 194kDa
chr20_+_55359551 2.367 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr4_+_6726699 2.360 LOC93622
hypothetical LOC93622
chr17_+_55325268 2.343 RPS6KB1
ribosomal protein S6 kinase, 70kDa, polypeptide 1
chr6_+_237033 2.296 NM_020185
DUSP22
dual specificity phosphatase 22
chr3_+_113180517 2.294 NM_018394
ABHD10
abhydrolase domain containing 10
chr6_+_41148665 2.279 NM_002505
NM_021705
NFYA

nuclear transcription factor Y, alpha

chr2_+_131966970 2.269 LOC150776
sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr17_+_32924110 2.253 DUSP14
dual specificity phosphatase 14
chr2_+_190234369 2.251 NM_019048
ASNSD1
asparagine synthetase domain containing 1
chr12_+_52960798 2.245 HNRNPA1L2
HNRNPA1
HNRNPA1P10
heterogeneous nuclear ribonucleoprotein A1-like 2
heterogeneous nuclear ribonucleoprotein A1
heterogeneous nuclear ribonucleoprotein A1 pseudogene 10
chr9_+_37069984 2.243 LOC100506710
hypothetical LOC100506710
chr10_-_127501683 2.232 UROS
uroporphyrinogen III synthase
chr12_+_129922570 2.223 RAN
RAN, member RAS oncogene family
chr17_-_55324859 2.216 NM_001193609
NM_001193610
NM_001193611
NM_001193612
NM_001193613
NM_016261
TUBD1





tubulin, delta 1





chr16_-_80761281 2.216 NM_005792
MPHOSPH6
M-phase phosphoprotein 6
chr9_+_114182216 2.188 HSDL2
hydroxysteroid dehydrogenase like 2
chr3_+_196870099 2.185 SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr19_-_5573725 2.174 SAFB2
scaffold attachment factor B2
chr16_+_14634324 2.166 BFAR
bifunctional apoptosis regulator
chr21_-_37367259 2.163 NM_153682
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_2710560 2.161 WRNIP1
Werner helicase interacting protein 1
chr20_+_25124457 2.144 ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr20_+_55359992 2.139 NM_001015885
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chr2_+_26110487 2.135 RAB10
RAB10, member RAS oncogene family
chr13_+_36291306 2.127 NM_000538
RFXAP
regulatory factor X-associated protein
chr2_+_26110232 2.107 NM_016131
RAB10
RAB10, member RAS oncogene family
chr3_+_180348818 2.086 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr14_+_99507848 2.065 EVL
Enah/Vasp-like
chr4_+_146238936 2.063 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr3_+_37259684 2.040 NM_001172713
NM_002078
GOLGA4

golgin A4

chr19_-_5573794 2.036 NM_014649
SAFB2
scaffold attachment factor B2
chr3_+_15222747 2.036 CAPN7
calpain 7
chr2_+_54638957 2.035 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr7_+_107318852 2.028 DLD
dihydrolipoamide dehydrogenase
chr7_+_107318854 2.025 DLD
dihydrolipoamide dehydrogenase
chr2_-_207338247 2.024 NM_001039845
MDH1B
malate dehydrogenase 1B, NAD (soluble)
chr2_+_207338356 2.021 NM_001136193
NM_001136194
NM_014929
FASTKD2


FAST kinase domains 2


chr3_+_49702018 2.011 RNF123
ring finger protein 123
chr6_+_2710602 2.008 NM_020135
NM_130395
WRNIP1

Werner helicase interacting protein 1

chr21_+_39674112 1.999 WRB
tryptophan rich basic protein
chr16_+_31098931 1.998 NM_001170634
NM_001170937
NM_004960
FUS


fused in sarcoma


chr2_+_69910277 1.992 NM_178439
GMCL1
germ cell-less homolog 1 (Drosophila)
chr21_+_39674138 1.983 WRB
tryptophan rich basic protein
chr20_-_13713509 1.980 NM_016649
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr9_+_114182009 1.979 NM_001195822
NM_032303
HSDL2

hydroxysteroid dehydrogenase like 2

chr2_+_28828332 1.953 PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr7_+_107318821 1.949 NM_000108
DLD
dihydrolipoamide dehydrogenase
chr11_+_63205444 1.946 NM_006054
NM_201428
NM_201429
NM_201430
RTN3



reticulon 3



chr10_+_27833167 1.932 NM_021252
RAB18
RAB18, member RAS oncogene family
chr18_+_10516022 1.932 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr17_+_46692908 1.924 UTP18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr7_-_116854765 1.924 NM_130768
ASZ1
ankyrin repeat, SAM and basic leucine zipper domain containing 1
chr7_+_107171514 1.924 NM_024814
CBLL1
Cas-Br-M (murine) ecotropic retroviral transforming sequence-like 1
chr5_+_112071087 1.922 NM_001127511
APC
adenomatous polyposis coli
chr16_+_31098959 1.919 FUS
fused in sarcoma
chr10_+_133995587 1.918 NM_001143758
NM_001143759
NM_030626
LRRC27


leucine rich repeat containing 27


chr9_+_90193058 1.914 NM_006717
SPIN1
spindlin 1
chr5_+_79739548 1.906 NM_001105251
NM_014733
ZFYVE16

zinc finger, FYVE domain containing 16

chr4_+_141514187 1.903 SCOC
short coiled-coil protein
chr7_+_107997527 1.898 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr5_+_154218389 1.897 NM_004779
CNOT8
CCR4-NOT transcription complex, subunit 8
chr10_-_127501822 1.891 NM_000375
UROS
uroporphyrinogen III synthase
chr3_+_49701978 1.891 NM_022064
RNF123
ring finger protein 123
chr2_+_241904013 1.889 SEPT2
septin 2
chr17_+_46692891 1.888 NM_016001
UTP18
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr16_+_31098962 1.886 FUS
fused in sarcoma
chr21_+_39674082 1.885 NM_004627
WRB
tryptophan rich basic protein
chr22_-_26645150 1.885 PITPNB
phosphatidylinositol transfer protein, beta
chr22_-_26645202 1.883 PITPNB
phosphatidylinositol transfer protein, beta
chr7_+_107997544 1.878 NM_012328
DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr7_+_158341961 1.877 NM_018051
WDR60
WD repeat domain 60
chr22_-_26645214 1.875 NM_012399
PITPNB
phosphatidylinositol transfer protein, beta
chr9_+_45331898 1.870 LOC100132167
hypothetical LOC100132167
chr2_+_216682251 1.863 NM_021141
XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr6_+_13682628 1.853 NM_001193267
NM_031244
NM_012241
SIRT5


sirtuin 5


chr2_+_131579334 1.849 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr8_-_125555933 1.848


chr4_+_141514251 1.845 SCOC
short coiled-coil protein
chr3_+_43707362 1.832 NM_016006
ABHD5
abhydrolase domain containing 5
chr12_+_68418829 1.832 NM_022456
NM_175624
RAB3IP

RAB3A interacting protein (rabin3)

chr17_+_42963737 1.823 NPEPPS
aminopeptidase puromycin sensitive
chr18_+_46810598 1.816 SMAD4
SMAD family member 4
chr8_+_42368550 1.810 VDAC3
voltage-dependent anion channel 3
chr10_+_105716925 1.810 SLK
STE20-like kinase
chr20_+_41519947 1.806 SRSF6
serine/arginine-rich splicing factor 6
chr2_+_242679507 1.798 LOC728323
hypothetical LOC728323
chr2_+_241904024 1.793 SEPT2
septin 2
chr21_-_37366684 1.787 NM_153681
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr7_+_116289833 1.785 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr16_+_8622974 1.777 NM_024109
METTL22
methyltransferase like 22
chr2_+_241903943 1.769 NM_001008492
NM_004404
SEPT2

septin 2

chr2_+_241904038 1.762 SEPT2
septin 2
chr16_+_31098963 1.748 FUS
fused in sarcoma
chr22_-_21814208 1.748 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr8_-_125555989 1.740


chr3_+_49701965 1.737 RNF123
ring finger protein 123
chr17_+_30331579 1.736 NM_002311
NM_013975
LIG3

ligase III, DNA, ATP-dependent

chr8_+_42368533 1.731 VDAC3
voltage-dependent anion channel 3
chr2_+_196229715 1.724 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr17_+_42963636 1.724 NPEPPS
aminopeptidase puromycin sensitive
chr11_+_64857921 1.714 NM_006268
DPF2
D4, zinc and double PHD fingers family 2
chr16_+_31098971 1.708 FUS
fused in sarcoma
chr9_+_99214000 1.707 NM_014290
TDRD7
tudor domain containing 7
chr2_-_241903787 1.703 HDLBP
high density lipoprotein binding protein
chr12_+_52960745 1.702 NM_002136
NM_031157
HNRNPA1

heterogeneous nuclear ribonucleoprotein A1

chr15_-_66900266 1.701 ANP32A
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr18_+_10515861 1.701 NM_003826
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr11_+_75833707 1.697 NM_020193
C11orf30
chromosome 11 open reading frame 30
chr18_+_10516044 1.694 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr7_+_116289827 1.693 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr4_+_25931745 1.685 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_+_146238818 1.685 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.48 1.08e-28 GO:0044260 cellular macromolecule metabolic process
1.33 2.57e-23 GO:0044237 cellular metabolic process
1.38 4.81e-21 GO:0043170 macromolecule metabolic process
1.60 4.49e-18 GO:0090304 nucleic acid metabolic process
1.51 1.60e-17 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 3.30e-17 GO:0044238 primary metabolic process
1.25 1.23e-16 GO:0008152 metabolic process
1.43 1.55e-14 GO:0034641 cellular nitrogen compound metabolic process
1.41 1.09e-13 GO:0006807 nitrogen compound metabolic process
1.58 9.09e-12 GO:0006996 organelle organization
1.54 1.28e-11 GO:0010467 gene expression
1.45 1.50e-11 GO:0044267 cellular protein metabolic process
2.00 1.58e-11 GO:0051276 chromosome organization
1.97 3.94e-11 GO:0006396 RNA processing
1.54 1.09e-10 GO:0016070 RNA metabolic process
1.39 1.97e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.98 2.81e-09 GO:0016071 mRNA metabolic process
1.38 1.10e-08 GO:0071842 cellular component organization at cellular level
1.97 1.72e-08 GO:0006974 response to DNA damage stimulus
2.26 4.22e-08 GO:0008380 RNA splicing
1.99 4.30e-08 GO:0006325 chromatin organization
1.87 6.10e-08 GO:0006259 DNA metabolic process
2.08 8.46e-08 GO:0006397 mRNA processing
2.16 9.66e-08 GO:0006281 DNA repair
1.70 1.51e-07 GO:0033554 cellular response to stress
2.50 2.74e-07 GO:0000375 RNA splicing, via transesterification reactions
1.32 7.23e-07 GO:0019538 protein metabolic process
2.47 9.51e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.47 9.51e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
1.10 1.01e-06 GO:0009987 cellular process
1.44 3.47e-06 GO:0034645 cellular macromolecule biosynthetic process
1.43 6.70e-06 GO:0009059 macromolecule biosynthetic process
1.26 6.37e-05 GO:0071840 cellular component organization or biogenesis
1.82 1.35e-04 GO:0000279 M phase
1.25 1.57e-04 GO:0016043 cellular component organization
1.58 2.29e-04 GO:0046907 intracellular transport
1.88 2.36e-04 GO:0034622 cellular macromolecular complex assembly
1.88 2.48e-04 GO:0044419 interspecies interaction between organisms
1.75 2.53e-04 GO:0034621 cellular macromolecular complex subunit organization
1.72 2.84e-04 GO:0044265 cellular macromolecule catabolic process
1.94 4.55e-04 GO:0006412 translation
1.48 4.57e-04 GO:0008104 protein localization
2.43 4.87e-04 GO:0006310 DNA recombination
1.34 6.20e-04 GO:0043412 macromolecule modification
3.05 8.27e-04 GO:0006302 double-strand break repair
1.29 8.40e-04 GO:0044249 cellular biosynthetic process
1.62 1.19e-03 GO:0009057 macromolecule catabolic process
1.55 1.54e-03 GO:0071844 cellular component assembly at cellular level
1.58 1.65e-03 GO:0022403 cell cycle phase
1.80 2.07e-03 GO:0016568 chromatin modification
2.33 2.18e-03 GO:0006333 chromatin assembly or disassembly
1.81 2.34e-03 GO:0051301 cell division
1.50 2.40e-03 GO:0045184 establishment of protein localization
1.33 2.47e-03 GO:0006464 protein modification process
1.27 2.48e-03 GO:0009058 biosynthetic process
1.41 5.02e-03 GO:0044248 cellular catabolic process
1.40 6.11e-03 GO:0044085 cellular component biogenesis
1.48 6.91e-03 GO:0015031 protein transport
1.38 7.65e-03 GO:0033036 macromolecule localization
2.87 7.77e-03 GO:0006200 ATP catabolic process
1.71 8.46e-03 GO:0016032 viral reproduction
1.90 9.49e-03 GO:0016567 protein ubiquitination
1.37 1.43e-02 GO:0051641 cellular localization
1.84 1.78e-02 GO:0032446 protein modification by small protein conjugation
1.72 2.07e-02 GO:0030163 protein catabolic process
2.24 2.28e-02 GO:0046034 ATP metabolic process
1.41 2.46e-02 GO:0007049 cell cycle
2.12 2.48e-02 GO:0000226 microtubule cytoskeleton organization
1.46 2.59e-02 GO:0022402 cell cycle process
1.40 3.16e-02 GO:0022607 cellular component assembly
1.73 3.39e-02 GO:0044257 cellular protein catabolic process
1.82 3.58e-02 GO:0034660 ncRNA metabolic process
1.49 3.80e-02 GO:0065003 macromolecular complex assembly
1.77 4.62e-02 GO:0009199 ribonucleoside triphosphate metabolic process
2.09 4.63e-02 GO:0071103 DNA conformation change

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 2.40e-51 GO:0005622 intracellular
1.23 4.95e-48 GO:0044424 intracellular part
1.32 5.91e-45 GO:0043231 intracellular membrane-bounded organelle
1.31 1.20e-44 GO:0043227 membrane-bounded organelle
1.28 3.39e-44 GO:0043229 intracellular organelle
1.27 1.17e-43 GO:0043226 organelle
1.43 4.91e-35 GO:0005634 nucleus
1.37 2.17e-26 GO:0044446 intracellular organelle part
1.36 3.85e-25 GO:0044422 organelle part
1.64 3.80e-22 GO:0044428 nuclear part
1.57 2.81e-18 GO:0070013 intracellular organelle lumen
1.56 3.94e-18 GO:0031974 membrane-enclosed lumen
1.55 1.54e-17 GO:0043233 organelle lumen
1.21 1.79e-17 GO:0005737 cytoplasm
1.62 5.01e-17 GO:0031981 nuclear lumen
1.38 9.93e-15 GO:0032991 macromolecular complex
1.69 4.33e-14 GO:0005654 nucleoplasm
2.02 9.66e-12 GO:0005694 chromosome
1.99 2.89e-10 GO:0030529 ribonucleoprotein complex
1.36 2.78e-09 GO:0043228 non-membrane-bounded organelle
1.36 2.78e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.21 7.54e-09 GO:0044444 cytoplasmic part
1.97 1.34e-08 GO:0044427 chromosomal part
1.05 2.33e-08 GO:0044464 cell part
1.05 2.45e-08 GO:0005623 cell
1.28 5.91e-06 GO:0043234 protein complex
1.34 1.59e-05 GO:0005829 cytosol
1.92 1.90e-05 GO:0005815 microtubule organizing center
2.13 3.19e-05 GO:0005813 centrosome
2.55 5.67e-05 GO:0044455 mitochondrial membrane part
2.06 8.05e-05 GO:0000785 chromatin
1.60 9.42e-05 GO:0015630 microtubule cytoskeleton
1.40 1.40e-04 GO:0005739 mitochondrion
2.40 1.85e-04 GO:0005681 spliceosomal complex
1.53 5.76e-04 GO:0044451 nucleoplasm part
2.11 7.14e-04 GO:0005819 spindle
1.51 1.79e-03 GO:0031967 organelle envelope
1.48 4.14e-03 GO:0031975 envelope
1.50 4.45e-03 GO:0044429 mitochondrial part
2.11 1.17e-02 GO:0000151 ubiquitin ligase complex
2.49 2.83e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
1.93 2.96e-02 GO:0044454 nuclear chromosome part
3.03 4.76e-02 GO:0008287 protein serine/threonine phosphatase complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.25 4.99e-18 GO:0005515 protein binding
1.40 1.11e-14 GO:0003676 nucleic acid binding
1.12 6.18e-13 GO:0005488 binding
1.79 5.15e-11 GO:0003723 RNA binding
1.20 2.35e-06 GO:0003824 catalytic activity
1.34 4.08e-06 GO:0000166 nucleotide binding
1.31 6.11e-05 GO:0003677 DNA binding
1.30 1.48e-03 GO:0017076 purine nucleotide binding
1.31 1.51e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.83 1.68e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.65 2.18e-03 GO:0016874 ligase activity
1.29 2.73e-03 GO:0032553 ribonucleotide binding
1.29 2.73e-03 GO:0032555 purine ribonucleotide binding
1.83 5.37e-03 GO:0016881 acid-amino acid ligase activity
2.13 5.67e-03 GO:0004518 nuclease activity
2.96 6.02e-03 GO:0003697 single-stranded DNA binding
1.46 6.21e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.46 7.54e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.31 7.91e-03 GO:0030554 adenyl nucleotide binding
1.45 8.25e-03 GO:0016462 pyrophosphatase activity
1.31 1.21e-02 GO:0005524 ATP binding
1.45 1.57e-02 GO:0017111 nucleoside-triphosphatase activity
1.30 1.60e-02 GO:0032559 adenyl ribonucleotide binding
2.18 4.95e-02 GO:0016779 nucleotidyltransferase activity