Motif ID: NRF1.p2

Z-value: 5.389


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NRF1chr7_+_1290388150.792.6e-04Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_254742 6.373 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chr20_+_48781457 6.043 NM_032521
 PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr2_+_254843 5.374 NM_001040649
NM_004300
NM_007099
 ACP1


acid phosphatase 1, soluble


chr2_+_118562499 5.080 NM_016133
 INSIG2
insulin induced gene 2
chr12_+_105873803 4.864 C12orf23
chromosome 12 open reading frame 23
chr1_+_227473638 4.741 RAB4A
RAB4A, member RAS oncogene family
chr2_+_28828112 4.537 NM_206876
NM_002709
 PPP1CB

protein phosphatase 1, catalytic subunit, beta isozyme

chr12_+_105873669 4.450 NM_152261
 C12orf23
chromosome 12 open reading frame 23
chr6_+_41148869 4.266 NFYA
nuclear transcription factor Y, alpha
chr15_+_22751162 4.240 NM_003097
NM_022804
NM_005678
 SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr5_+_52131686 4.131 PELO
pelota homolog (Drosophila)
chr9_+_109085337 4.129 NM_002874
 RAD23B
RAD23 homolog B (S. cerevisiae)
chr14_+_22633728 4.108 C14orf119
chromosome 14 open reading frame 119
chr1_+_227473458 4.018 NM_004578
 RAB4A
RAB4A, member RAS oncogene family
chr9_+_109085372 3.993 RAD23B
RAD23 homolog B (S. cerevisiae)
chr21_+_33619147 3.830 IFNAR1
interferon (alpha, beta and omega) receptor 1
chr9_+_109085386 3.810 RAD23B
RAD23 homolog B (S. cerevisiae)
chr2_+_71412348 3.717 NM_001014972
NM_014497
 ZNF638

zinc finger protein 638

chr5_+_72287625 3.703


chr20_+_39091026 3.660 TOP1
topoisomerase (DNA) I

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 75 entries
enrichment   p-value GO term description
3.05 8.27e-04 GO:0006302 double-strand break repair
2.87 7.77e-03 GO:0006200 ATP catabolic process
2.50 2.74e-07 GO:0000375 RNA splicing, via transesterification reactions
2.47 9.51e-07 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.47 9.51e-07 GO:0000398 nuclear mRNA splicing, via spliceosome
2.43 4.87e-04 GO:0006310 DNA recombination
2.33 2.18e-03 GO:0006333 chromatin assembly or disassembly
2.26 4.22e-08 GO:0008380 RNA splicing
2.24 2.28e-02 GO:0046034 ATP metabolic process
2.16 9.66e-08 GO:0006281 DNA repair
2.12 2.48e-02 GO:0000226 microtubule cytoskeleton organization
2.09 4.63e-02 GO:0071103 DNA conformation change
2.08 8.46e-08 GO:0006397 mRNA processing
2.00 1.58e-11 GO:0051276 chromosome organization
1.99 4.30e-08 GO:0006325 chromatin organization
1.98 2.81e-09 GO:0016071 mRNA metabolic process
1.97 3.94e-11 GO:0006396 RNA processing
1.97 1.72e-08 GO:0006974 response to DNA damage stimulus
1.94 4.55e-04 GO:0006412 translation
1.90 9.49e-03 GO:0016567 protein ubiquitination

Gene overrepresentation in compartment category:

Showing 1 to 20 of 43 entries
enrichment   p-value GO term description
3.03 4.76e-02 GO:0008287 protein serine/threonine phosphatase complex
2.55 5.67e-05 GO:0044455 mitochondrial membrane part
2.49 2.83e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.40 1.85e-04 GO:0005681 spliceosomal complex
2.13 3.19e-05 GO:0005813 centrosome
2.11 7.14e-04 GO:0005819 spindle
2.11 1.17e-02 GO:0000151 ubiquitin ligase complex
2.06 8.05e-05 GO:0000785 chromatin
2.02 9.66e-12 GO:0005694 chromosome
1.99 2.89e-10 GO:0030529 ribonucleoprotein complex
1.97 1.34e-08 GO:0044427 chromosomal part
1.93 2.96e-02 GO:0044454 nuclear chromosome part
1.92 1.90e-05 GO:0005815 microtubule organizing center
1.69 4.33e-14 GO:0005654 nucleoplasm
1.64 3.80e-22 GO:0044428 nuclear part
1.62 5.01e-17 GO:0031981 nuclear lumen
1.60 9.42e-05 GO:0015630 microtubule cytoskeleton
1.57 2.81e-18 GO:0070013 intracellular organelle lumen
1.56 3.94e-18 GO:0031974 membrane-enclosed lumen
1.55 1.54e-17 GO:0043233 organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
2.96 6.02e-03 GO:0003697 single-stranded DNA binding
2.18 4.95e-02 GO:0016779 nucleotidyltransferase activity
2.13 5.67e-03 GO:0004518 nuclease activity
1.83 1.68e-03 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.83 5.37e-03 GO:0016881 acid-amino acid ligase activity
1.79 5.15e-11 GO:0003723 RNA binding
1.65 2.18e-03 GO:0016874 ligase activity
1.46 6.21e-03 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.46 7.54e-03 GO:0016817 hydrolase activity, acting on acid anhydrides
1.45 8.25e-03 GO:0016462 pyrophosphatase activity
1.45 1.57e-02 GO:0017111 nucleoside-triphosphatase activity
1.40 1.11e-14 GO:0003676 nucleic acid binding
1.34 4.08e-06 GO:0000166 nucleotide binding
1.31 6.11e-05 GO:0003677 DNA binding
1.31 1.51e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.31 7.91e-03 GO:0030554 adenyl nucleotide binding
1.31 1.21e-02 GO:0005524 ATP binding
1.30 1.48e-03 GO:0017076 purine nucleotide binding
1.30 1.60e-02 GO:0032559 adenyl ribonucleotide binding
1.29 2.73e-03 GO:0032553 ribonucleotide binding