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• Activity deltas table
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Motif ID: SOX2.p2

Z-value: 1.009

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_21087435	1.771		APOB	apolipoprotein B (including Ag(x) antigen)
chr2_-_21084077	1.331		APOB	apolipoprotein B (including Ag(x) antigen)
chr3_-_192531018	1.314	NM_198152	UTS2D	urotensin 2 domain containing
chr20_+_11846536	1.301	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr5_+_147754467	1.284		FBXO38	F-box protein 38
chr2_+_152900076	1.147		FMNL2	formin-like 2
chr17_+_63252704	1.141		BPTF	bromodomain PHD finger transcription factor
chr20_+_2892918	1.090		PTPRA	protein tyrosine phosphatase, receptor type, A
chr16_+_21518633	1.065		METTL9	methyltransferase like 9
chr3_+_142587973	1.037
chr2_+_62787534	0.992	NM_001142614	EHBP1	EH domain binding protein 1
chr2_+_203207912	0.980		FAM117B	family with sequence similarity 117, member B
chr17_+_63252668	0.953		BPTF	bromodomain PHD finger transcription factor
chr4_+_146623405	0.938	NM_001003688	SMAD1	SMAD family member 1
chr1_+_61320213	0.918	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr1_+_61319976	0.905	NM_001145512	NFIA	nuclear factor I/A
chr6_+_122762449	0.897		HSF2	heat shock transcription factor 2
chr2_+_101680594	0.895	NM_004834 NM_145686 NM_145687	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_86659370	0.883	NM_019117 NM_057162	KLHL4	kelch-like 4 (Drosophila)
chr2_+_120233676	0.862	NM_002830	PTPN4	protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr4_-_101658094	0.853	NM_001159694 NM_016242	EMCN	endomucin
chr2_-_174475528	0.816
chr4_+_110968594	0.802	NM_006583	RRH	retinal pigment epithelium-derived rhodopsin homolog
chr14_+_31868229	0.790	NM_004274	AKAP6	A kinase (PRKA) anchor protein 6
chr6_-_127882192	0.784	NM_001012279	C6orf174	chromosome 6 open reading frame 174
chr6_+_122762384	0.768	NM_001135564 NM_004506	HSF2	heat shock transcription factor 2
chr13_+_23042722	0.752	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr10_+_49184658	0.739		MAPK8	mitogen-activated protein kinase 8
chr8_+_21833162	0.734		XPO7	exportin 7
chr4_+_113372287	0.722	NM_001128426 NM_018569	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr6_+_64414389	0.722	NM_015153	PHF3	PHD finger protein 3
chr9_+_90193058	0.703	NM_006717	SPIN1	spindlin 1
chr3_+_186563529	0.698	NM_004721	MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr10_-_11614279	0.696	NM_001080491	USP6NL	USP6 N-terminal like
chr14_-_30927931	0.686	NM_015473	HEATR5A	HEAT repeat containing 5A
chr2_+_169021039	0.671	NM_203463	LASS6	LAG1 homolog, ceramide synthase 6
chr18_+_3441589	0.671	NM_170695 NM_173210	TGIF1	TGFB-induced factor homeobox 1
chr2_+_181554048	0.670		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr9_-_85773899	0.670		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr10_-_61570665	0.666	NM_001149	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr9_+_114289178	0.664		KIAA1958	KIAA1958
chr2_-_63518589	0.662	NM_001042692	WDPCP	WD repeat containing planar cell polarity effector
chr10_+_114699953	0.622	NM_001146274 NM_001146283 NM_001146284 NM_001146285 NM_001146286 NM_001198525 NM_001198526 NM_001198527 NM_001198528 NM_001198529 NM_001198530 NM_001198531 NM_030756	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr9_+_112470871	0.621	NM_001166280 NM_001166281 NM_005592	MUSK	muscle, skeletal, receptor tyrosine kinase
chr7_+_94135384	0.620		PEG10	paternally expressed 10
chr16_+_55373241	0.612		NUP93	nucleoporin 93kDa
chr1_+_90233238	0.611	NM_182975 NM_182976	ZNF326	zinc finger protein 326
chr6_+_144649142	0.610		UTRN	utrophin
chr8_+_21833111	0.599	NM_015024	XPO7	exportin 7
chr15_+_47502666	0.599	NM_002009	FGF7	fibroblast growth factor 7
chr6_-_128263868	0.596	NM_001010923 NM_001164685	THEMIS	thymocyte selection associated
chr6_-_50045296	0.587	NM_001037729	DEFB113	defensin, beta 113
chr17_+_55269974	0.578
chr13_-_40491491	0.571	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr15_+_50098724	0.569		MAPK6	mitogen-activated protein kinase 6
chr15_+_50098700	0.560	NM_002748	MAPK6	mitogen-activated protein kinase 6
chr4_+_115762971	0.558	NM_003360	UGT8	UDP glycosyltransferase 8
chr8_+_81560971	0.557	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr9_+_71009746	0.539	NM_001170415 NM_001170416	TJP2	tight junction protein 2 (zona occludens 2)
chr2_-_37752272	0.537		CDC42EP3	CDC42 effector protein (Rho GTPase binding) 3
chr13_-_98428244	0.536	NM_001130048 NM_001130050	DOCK9	dedicator of cytokinesis 9
chr12_-_10464308	0.533	NM_002261 NM_007333	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr7_+_16759845	0.528	NM_014399	TSPAN13	tetraspanin 13
chr5_+_36912656	0.527		NIPBL	Nipped-B homolog (Drosophila)
chrX_+_123062143	0.526		STAG2	stromal antigen 2
chrX_+_44617346	0.524	NM_021140	KDM6A	lysine (K)-specific demethylase 6A
chr1_+_183281173	0.522	NM_007212	RNF2	ring finger protein 2
chr1_+_198975227	0.519	NM_203459	CAMSAP1L1	calmodulin regulated spectrin-associated protein 1-like 1
chr6_-_128883125	0.517	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr12_-_65359019	0.513		GRIP1	glutamate receptor interacting protein 1
chr12_-_11041740	0.512	NM_176889	TAS2R20	taste receptor, type 2, member 20
chr3_+_153469421	0.508		MBNL1	muscleblind-like (Drosophila)
chrX_+_84385693	0.508		ZNF711	zinc finger protein 711
chr6_+_157141565	0.499		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr2_+_198377561	0.497	NM_006226	PLCL1	phospholipase C-like 1
chr14_+_22059174	0.496
chr15_+_50098730	0.496		MAPK6	mitogen-activated protein kinase 6
chr4_+_166350620	0.491	NM_001161521 NM_001161522	KLHL2	kelch-like 2, Mayven (Drosophila)
chr2_+_46779827	0.485	NM_144949	SOCS5	suppressor of cytokine signaling 5
chr15_-_23204887	0.483	NM_000462	UBE3A	ubiquitin protein ligase E3A
chr2_+_166137091	0.481	NM_024969	CSRNP3	cysteine-serine-rich nuclear protein 3
chr17_+_50333021	0.481	NM_005486	TOM1L1	target of myb1 (chicken)-like 1
chr7_-_11838260	0.479	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chr17_-_53420473	0.477		VEZF1	vascular endothelial zinc finger 1
chr2_-_156897286	0.474	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr2_+_203208064	0.474	NM_173511	FAM117B	family with sequence similarity 117, member B
chr2_-_55413253	0.472		CCDC88A	coiled-coil domain containing 88A
chr2_+_36436873	0.468	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_+_144654565	0.467	NM_007124	UTRN	utrophin
chr6_+_64340408	0.465		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr7_-_26202626	0.464		HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_138705445	0.462		PAIP2	poly(A) binding protein interacting protein 2
chr16_-_69876262	0.461		FTSJD1	FtsJ methyltransferase domain containing 1
chr7_+_106897737	0.461	NM_005295	GPR22	G protein-coupled receptor 22
chr20_-_33705244	0.459	NM_003915	CPNE1	copine I
chr12_-_65359148	0.457	NM_001178074 NM_021150	GRIP1	glutamate receptor interacting protein 1
chr3_-_150993299	0.455	NM_001144960	C3orf16	chromosome 3 open reading frame 16
chr4_+_39376058	0.455	NM_001111112 NM_001111113 NM_005339	UBE2K	ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)
chr21_+_29593607	0.454	NM_206866	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_48980858	0.453	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr4_+_35959638	0.453	NM_001136536	DTHD1	death domain containing 1
chr5_+_138705469	0.452		PAIP2	poly(A) binding protein interacting protein 2
chr6_+_64340388	0.450		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr2_-_55053398	0.448
chr8_+_110415725	0.448	NM_001193557 NM_020189	ENY2	enhancer of yellow 2 homolog (Drosophila)
chr4_+_144654005	0.443	NM_003601	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_-_44424423	0.443	NM_004465	FGF10	fibroblast growth factor 10
chr1_-_151296611	0.443	NM_005988	SPRR2A	small proline-rich protein 2A
chr17_+_36642240	0.441	NM_031962	KRTAP9-9 KRTAP9-3	keratin associated protein 9-9 keratin associated protein 9-3
chr1_-_52293634	0.437	NM_015913	TXNDC12	thioredoxin domain containing 12 (endoplasmic reticulum)
chr2_-_188021117	0.434	NM_005795	CALCRL	calcitonin receptor-like
chr8_-_110415448	0.434	NM_032869	NUDCD1	NudC domain containing 1
chr7_+_116099648	0.434	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr15_+_21361546	0.433	NM_005664	MKRN3	makorin ring finger protein 3
chr2_-_36929520	0.431		STRN	striatin, calmodulin binding protein
chr2_+_114935623	0.428	NM_001178036	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr6_+_57062974	0.427		ZNF451	zinc finger protein 451
chr17_-_53420595	0.427	NM_007146	VEZF1	vascular endothelial zinc finger 1
chr5_+_102493155	0.426	NM_015216	PPIP5K2	diphosphoinositol pentakisphosphate kinase 2
chr10_+_92970302	0.425	NM_032373	PCGF5	polycomb group ring finger 5
chr1_-_95165037	0.424		CNN3	calponin 3, acidic
chr9_+_18464090	0.421	NM_001040272 NM_052866	ADAMTSL1	ADAMTS-like 1
chr3_-_121065112	0.419
chr6_-_33028790	0.418	NM_006120	HLA-DMA	major histocompatibility complex, class II, DM alpha
chr4_+_144654526	0.418
chr2_+_54537842	0.417		SPTBN1	spectrin, beta, non-erythrocytic 1
chr2_+_187163232	0.417		ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr20_+_30831298	0.416	NM_175850	DNMT3B	DNA (cytosine-5-)-methyltransferase 3 beta
chr12_-_23995220	0.415		SOX5	SRY (sex determining region Y)-box 5
chr12_-_23995109	0.415		SOX5	SRY (sex determining region Y)-box 5
chr14_-_22521544	0.415	NM_032876	JUB	jub, ajuba homolog (Xenopus laevis)
chr1_-_95165089	0.414	NM_001839	CNN3	calponin 3, acidic
chr2_-_21081694	0.414		APOB	apolipoprotein B (including Ag(x) antigen)
chr14_+_34831355	0.413		PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr10_+_111959978	0.409	NM_001008541	MXI1	MAX interactor 1
chr2_+_201385019	0.405		BZW1	basic leucine zipper and W2 domains 1
chr2_+_11600238	0.405		GREB1	growth regulation by estrogen in breast cancer 1
chr5_+_10406980	0.405
chr15_+_22751162	0.404	NM_003097 NM_022804 NM_005678	SNRPN SNURF	small nuclear ribonucleoprotein polypeptide N SNRPN upstream reading frame
chr5_+_161427225	0.403	NM_000816 NM_198903 NM_198904	GABRG2	gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr20_-_45410033	0.402		ZMYND8	zinc finger, MYND-type containing 8
chr2_+_138438277	0.401	NM_001024074 NM_001024075 NM_006895	HNMT	histamine N-methyltransferase
chr2_+_108751033	0.401		RANBP2	RAN binding protein 2
chr3_+_112743615	0.398	NM_005816 NM_198196	CD96	CD96 molecule
chr8_-_17624009	0.397	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr6_+_89847183	0.396		PNRC1	proline-rich nuclear receptor coactivator 1
chr5_-_160211623	0.394	NM_025153	ATP10B	ATPase, class V, type 10B
chr12_-_97812633	0.392		ANKS1B	ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_146622154	0.390	NM_005900	SMAD1	SMAD family member 1
chr11_+_9552809	0.390	NM_001143976	WEE1	WEE1 homolog (S. pombe)
chr12_+_67919583	0.390	NM_007007	CPSF6	cleavage and polyadenylation specific factor 6, 68kDa
chr4_+_25931745	0.390		RBPJ	recombination signal binding protein for immunoglobulin kappa J region
chr12_-_11439752	0.387	NM_006248	PRB1 PRB2	proline-rich protein BstNI subfamily 1 proline-rich protein BstNI subfamily 2
chr19_+_44886785	0.385	NM_020129 NM_203471	LGALS14	lectin, galactoside-binding, soluble, 14
chr10_+_92970487	0.384		PCGF5	polycomb group ring finger 5
chr8_+_59486376	0.382	NM_001077619	UBXN2B	UBX domain protein 2B
chr4_-_83566045	0.381
chr2_-_207739815	0.375		KLF7	Kruppel-like factor 7 (ubiquitous)
chr2_+_201384889	0.375	NM_014670	BZW1	basic leucine zipper and W2 domains 1
chr6_+_64403668	0.374		PHF3	PHD finger protein 3
chr12_+_94135645	0.372	NM_017599	VEZT	vezatin, adherens junctions transmembrane protein
chr6_-_64087806	0.372	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr10_-_98326435	0.371		TM9SF3	transmembrane 9 superfamily member 3
chr1_-_196776697	0.371	NM_133262 NM_133326	ATP6V1G3	ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3
chr6_+_64403631	0.371		PHF3	PHD finger protein 3
chr2_+_171280046	0.371	NM_001003845	SP5	Sp5 transcription factor
chr13_-_40491405	0.370		ELF1	E74-like factor 1 (ets domain transcription factor)
chr14_+_56927066	0.370		NAA30	N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_201384842	0.369		BZW1	basic leucine zipper and W2 domains 1
chr5_+_90711887	0.369		LOC100129716	hypothetical LOC100129716
chr1_+_24158887	0.368	NM_017761	PNRC2	proline-rich nuclear receptor coactivator 2
chr9_+_90193807	0.368		SPIN1	spindlin 1
chr2_+_201384904	0.367		BZW1	basic leucine zipper and W2 domains 1
chr5_+_57914658	0.366	NM_138453	RAB3C	RAB3C, member RAS oncogene family
chr10_+_53744043	0.366	NM_012242	DKK1	dickkopf homolog 1 (Xenopus laevis)
chr2_-_210726539	0.365		C2orf67	chromosome 2 open reading frame 67
chr2_-_18634257	0.363	NM_001002006 NM_033253	NT5C1B-RDH14 NT5C1B	NT5C1B-RDH14 readthrough 5'-nucleotidase, cytosolic IB
chr6_-_134680888	0.362	NM_001143676	SGK1	serum/glucocorticoid regulated kinase 1
chr2_+_33213111	0.360	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr2_-_47986160	0.360	NM_001190274	FBXO11	F-box protein 11
chr3_+_23904086	0.359		UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr4_+_90252990	0.359	NM_145715	TIGD2	tigger transposable element derived 2
chr4_-_83566246	0.358		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr2_+_214984705	0.358	NM_001080500	VWC2L	von Willebrand factor C domain containing protein 2-like
chr16_-_20610078	0.357	NM_052956	ACSM1	acyl-CoA synthetase medium-chain family member 1
chr6_+_4721825	0.356		CDYL	chromodomain protein, Y-like
chr3_-_153470022	0.354		LOC401093	hypothetical LOC401093
chr14_+_56927014	0.353	NM_001011713	NAA30	N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_89847019	0.352	NM_006813	PNRC1	proline-rich nuclear receptor coactivator 1
chr12_-_88573949	0.351	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chrX_-_33267646	0.350	NM_000109	DMD	dystrophin
chr16_+_24475129	0.350		RBBP6	retinoblastoma binding protein 6
chr3_+_192529567	0.349	NM_174908 NM_178335	CCDC50	coiled-coil domain containing 50
chr6_+_88026338	0.348		ZNF292	zinc finger protein 292
chr7_+_93388951	0.348	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr5_+_65258250	0.347		ERBB2IP	erbb2 interacting protein
chr2_+_201384880	0.347		BZW1	basic leucine zipper and W2 domains 1
chr1_+_87569959	0.347		LMO4	LIM domain only 4
chr6_+_45404031	0.346	NM_001015051 NM_001024630	RUNX2	runt-related transcription factor 2
chr15_-_48198697	0.346	NM_024837	ATP8B4	ATPase, class I, type 8B, member 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.19	4.03e-06	GO:0032501	multicellular organismal process
1.80	8.07e-06	GO:0007608	sensory perception of smell
1.74	1.26e-05	GO:0007606	sensory perception of chemical stimulus
1.15	1.67e-04	GO:0050896	response to stimulus
1.36	1.12e-03	GO:0050877	neurological system process
1.31	1.14e-03	GO:0003008	system process
1.44	4.97e-03	GO:0007600	sensory perception
1.32	7.00e-03	GO:0007399	nervous system development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.85	7.12e-07	GO:0004984	olfactory receptor activity