Motif ID: SOX2.p2

Z-value: 1.009


Transcription factors associated with SOX2.p2:

Gene SymbolEntrez IDGene Name
SOX2 6657 SRY (sex determining region Y)-box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SOX2chr3_+_182912405-0.107.2e-01Click!


Activity profile for motif SOX2.p2.

activity profile for motif SOX2.p2


Sorted Z-values histogram for motif SOX2.p2

Sorted Z-values for motif SOX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_21087435 1.771 APOB
apolipoprotein B (including Ag(x) antigen)
chr2_-_21084077 1.331 APOB
apolipoprotein B (including Ag(x) antigen)
chr3_-_192531018 1.314 NM_198152
UTS2D
urotensin 2 domain containing
chr20_+_11846536 1.301 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr5_+_147754467 1.284 FBXO38
F-box protein 38
chr2_+_152900076 1.147 FMNL2
formin-like 2
chr17_+_63252704 1.141 BPTF
bromodomain PHD finger transcription factor
chr20_+_2892918 1.090 PTPRA
protein tyrosine phosphatase, receptor type, A
chr16_+_21518633 1.065 METTL9
methyltransferase like 9
chr3_+_142587973 1.037


chr2_+_62787534 0.992 NM_001142614
EHBP1
EH domain binding protein 1
chr2_+_203207912 0.980 FAM117B
family with sequence similarity 117, member B
chr17_+_63252668 0.953 BPTF
bromodomain PHD finger transcription factor
chr4_+_146623405 0.938 NM_001003688
SMAD1
SMAD family member 1
chr1_+_61320213 0.918 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61319976 0.905 NM_001145512
NFIA
nuclear factor I/A
chr6_+_122762449 0.897 HSF2
heat shock transcription factor 2
chr2_+_101680594 0.895 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chrX_+_86659370 0.883 NM_019117
NM_057162
KLHL4

kelch-like 4 (Drosophila)

chr2_+_120233676 0.862 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr4_-_101658094 0.853 NM_001159694
NM_016242
EMCN

endomucin

chr2_-_174475528 0.816


chr4_+_110968594 0.802 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr14_+_31868229 0.790 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr6_-_127882192 0.784 NM_001012279
C6orf174
chromosome 6 open reading frame 174
chr6_+_122762384 0.768 NM_001135564
NM_004506
HSF2

heat shock transcription factor 2

chr13_+_23042722 0.752 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr10_+_49184658 0.739 MAPK8
mitogen-activated protein kinase 8
chr8_+_21833162 0.734 XPO7
exportin 7
chr4_+_113372287 0.722 NM_001128426
NM_018569
AP1AR

adaptor-related protein complex 1 associated regulatory protein

chr6_+_64414389 0.722 NM_015153
PHF3
PHD finger protein 3
chr9_+_90193058 0.703 NM_006717
SPIN1
spindlin 1
chr3_+_186563529 0.698 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr10_-_11614279 0.696 NM_001080491
USP6NL
USP6 N-terminal like
chr14_-_30927931 0.686 NM_015473
HEATR5A
HEAT repeat containing 5A
chr2_+_169021039 0.671 NM_203463
LASS6
LAG1 homolog, ceramide synthase 6
chr18_+_3441589 0.671 NM_170695
NM_173210
TGIF1

TGFB-induced factor homeobox 1

chr2_+_181554048 0.670 UBE2E3
ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr9_-_85773899 0.670 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr10_-_61570665 0.666 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr9_+_114289178 0.664 KIAA1958
KIAA1958
chr2_-_63518589 0.662 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr10_+_114699953 0.622 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr9_+_112470871 0.621 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr7_+_94135384 0.620 PEG10
paternally expressed 10
chr16_+_55373241 0.612 NUP93
nucleoporin 93kDa
chr1_+_90233238 0.611 NM_182975
NM_182976
ZNF326

zinc finger protein 326

chr6_+_144649142 0.610 UTRN
utrophin
chr8_+_21833111 0.599 NM_015024
XPO7
exportin 7
chr15_+_47502666 0.599 NM_002009
FGF7
fibroblast growth factor 7
chr6_-_128263868 0.596 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr6_-_50045296 0.587 NM_001037729
DEFB113
defensin, beta 113
chr17_+_55269974 0.578


chr13_-_40491491 0.571 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr15_+_50098724 0.569 MAPK6
mitogen-activated protein kinase 6
chr15_+_50098700 0.560 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr4_+_115762971 0.558 NM_003360
UGT8
UDP glycosyltransferase 8
chr8_+_81560971 0.557 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr9_+_71009746 0.539 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr2_-_37752272 0.537 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr13_-_98428244 0.536 NM_001130048
NM_001130050
DOCK9

dedicator of cytokinesis 9

chr12_-_10464308 0.533 NM_002261
NM_007333
KLRC3

killer cell lectin-like receptor subfamily C, member 3

chr7_+_16759845 0.528 NM_014399
TSPAN13
tetraspanin 13
chr5_+_36912656 0.527 NIPBL
Nipped-B homolog (Drosophila)
chrX_+_123062143 0.526 STAG2
stromal antigen 2
chrX_+_44617346 0.524 NM_021140
KDM6A
lysine (K)-specific demethylase 6A
chr1_+_183281173 0.522 NM_007212
RNF2
ring finger protein 2
chr1_+_198975227 0.519 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr6_-_128883125 0.517 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr12_-_65359019 0.513 GRIP1
glutamate receptor interacting protein 1
chr12_-_11041740 0.512 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr3_+_153469421 0.508 MBNL1
muscleblind-like (Drosophila)
chrX_+_84385693 0.508 ZNF711
zinc finger protein 711
chr6_+_157141565 0.499 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr2_+_198377561 0.497 NM_006226
PLCL1
phospholipase C-like 1
chr14_+_22059174 0.496


chr15_+_50098730 0.496 MAPK6
mitogen-activated protein kinase 6
chr4_+_166350620 0.491 NM_001161521
NM_001161522
KLHL2

kelch-like 2, Mayven (Drosophila)

chr2_+_46779827 0.485 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr15_-_23204887 0.483 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr2_+_166137091 0.481 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr17_+_50333021 0.481 NM_005486
TOM1L1
target of myb1 (chicken)-like 1
chr7_-_11838260 0.479 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr17_-_53420473 0.477 VEZF1
vascular endothelial zinc finger 1
chr2_-_156897286 0.474 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_+_203208064 0.474 NM_173511
FAM117B
family with sequence similarity 117, member B
chr2_-_55413253 0.472 CCDC88A
coiled-coil domain containing 88A
chr2_+_36436873 0.468 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr6_+_144654565 0.467 NM_007124
UTRN
utrophin
chr6_+_64340408 0.465 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr7_-_26202626 0.464 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr5_+_138705445 0.462 PAIP2
poly(A) binding protein interacting protein 2
chr16_-_69876262 0.461 FTSJD1
FtsJ methyltransferase domain containing 1
chr7_+_106897737 0.461 NM_005295
GPR22
G protein-coupled receptor 22
chr20_-_33705244 0.459 NM_003915
CPNE1
copine I
chr12_-_65359148 0.457 NM_001178074
NM_021150
GRIP1

glutamate receptor interacting protein 1

chr3_-_150993299 0.455 NM_001144960
C3orf16
chromosome 3 open reading frame 16
chr4_+_39376058 0.455 NM_001111112
NM_001111113
NM_005339
UBE2K


ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast)


chr21_+_29593607 0.454 NM_206866
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr20_-_48980858 0.453 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr4_+_35959638 0.453 NM_001136536
DTHD1
death domain containing 1
chr5_+_138705469 0.452 PAIP2
poly(A) binding protein interacting protein 2
chr6_+_64340388 0.450 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr2_-_55053398 0.448


chr8_+_110415725 0.448 NM_001193557
NM_020189
ENY2

enhancer of yellow 2 homolog (Drosophila)

chr4_+_144654005 0.443 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_-_44424423 0.443 NM_004465
FGF10
fibroblast growth factor 10
chr1_-_151296611 0.443 NM_005988
SPRR2A
small proline-rich protein 2A
chr17_+_36642240 0.441 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr1_-_52293634 0.437 NM_015913
TXNDC12
thioredoxin domain containing 12 (endoplasmic reticulum)
chr2_-_188021117 0.434 NM_005795
CALCRL
calcitonin receptor-like
chr8_-_110415448 0.434 NM_032869
NUDCD1
NudC domain containing 1
chr7_+_116099648 0.434 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr15_+_21361546 0.433 NM_005664
MKRN3
makorin ring finger protein 3
chr2_-_36929520 0.431 STRN
striatin, calmodulin binding protein
chr2_+_114935623 0.428 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr6_+_57062974 0.427 ZNF451
zinc finger protein 451
chr17_-_53420595 0.427 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr5_+_102493155 0.426 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr10_+_92970302 0.425 NM_032373
PCGF5
polycomb group ring finger 5
chr1_-_95165037 0.424 CNN3
calponin 3, acidic
chr9_+_18464090 0.421 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr3_-_121065112 0.419


chr6_-_33028790 0.418 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr4_+_144654526 0.418


chr2_+_54537842 0.417 SPTBN1
spectrin, beta, non-erythrocytic 1
chr2_+_187163232 0.417 ITGAV
integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr20_+_30831298 0.416 NM_175850
DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr12_-_23995220 0.415 SOX5
SRY (sex determining region Y)-box 5
chr12_-_23995109 0.415 SOX5
SRY (sex determining region Y)-box 5
chr14_-_22521544 0.415 NM_032876
JUB
jub, ajuba homolog (Xenopus laevis)
chr1_-_95165089 0.414 NM_001839
CNN3
calponin 3, acidic
chr2_-_21081694 0.414 APOB
apolipoprotein B (including Ag(x) antigen)
chr14_+_34831355 0.413 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr10_+_111959978 0.409 NM_001008541
MXI1
MAX interactor 1
chr2_+_201385019 0.405 BZW1
basic leucine zipper and W2 domains 1
chr2_+_11600238 0.405 GREB1
growth regulation by estrogen in breast cancer 1
chr5_+_10406980 0.405


chr15_+_22751162 0.404 NM_003097
NM_022804
NM_005678
SNRPN
SNURF

small nuclear ribonucleoprotein polypeptide N
SNRPN upstream reading frame

chr5_+_161427225 0.403 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr20_-_45410033 0.402 ZMYND8
zinc finger, MYND-type containing 8
chr2_+_138438277 0.401 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_108751033 0.401 RANBP2
RAN binding protein 2
chr3_+_112743615 0.398 NM_005816
NM_198196
CD96

CD96 molecule

chr8_-_17624009 0.397 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr6_+_89847183 0.396 PNRC1
proline-rich nuclear receptor coactivator 1
chr5_-_160211623 0.394 NM_025153
ATP10B
ATPase, class V, type 10B
chr12_-_97812633 0.392 ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_146622154 0.390 NM_005900
SMAD1
SMAD family member 1
chr11_+_9552809 0.390 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr12_+_67919583 0.390 NM_007007
CPSF6
cleavage and polyadenylation specific factor 6, 68kDa
chr4_+_25931745 0.390 RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr12_-_11439752 0.387 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr19_+_44886785 0.385 NM_020129
NM_203471
LGALS14

lectin, galactoside-binding, soluble, 14

chr10_+_92970487 0.384 PCGF5
polycomb group ring finger 5
chr8_+_59486376 0.382 NM_001077619
UBXN2B
UBX domain protein 2B
chr4_-_83566045 0.381


chr2_-_207739815 0.375 KLF7
Kruppel-like factor 7 (ubiquitous)
chr2_+_201384889 0.375 NM_014670
BZW1
basic leucine zipper and W2 domains 1
chr6_+_64403668 0.374 PHF3
PHD finger protein 3
chr12_+_94135645 0.372 NM_017599
VEZT
vezatin, adherens junctions transmembrane protein
chr6_-_64087806 0.372 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr10_-_98326435 0.371 TM9SF3
transmembrane 9 superfamily member 3
chr1_-_196776697 0.371 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr6_+_64403631 0.371 PHF3
PHD finger protein 3
chr2_+_171280046 0.371 NM_001003845
SP5
Sp5 transcription factor
chr13_-_40491405 0.370 ELF1
E74-like factor 1 (ets domain transcription factor)
chr14_+_56927066 0.370 NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr2_+_201384842 0.369 BZW1
basic leucine zipper and W2 domains 1
chr5_+_90711887 0.369 LOC100129716
hypothetical LOC100129716
chr1_+_24158887 0.368 NM_017761
PNRC2
proline-rich nuclear receptor coactivator 2
chr9_+_90193807 0.368 SPIN1
spindlin 1
chr2_+_201384904 0.367 BZW1
basic leucine zipper and W2 domains 1
chr5_+_57914658 0.366 NM_138453
RAB3C
RAB3C, member RAS oncogene family
chr10_+_53744043 0.366 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr2_-_210726539 0.365 C2orf67
chromosome 2 open reading frame 67
chr2_-_18634257 0.363 NM_001002006
NM_033253
NT5C1B-RDH14
NT5C1B

NT5C1B-RDH14 readthrough
5'-nucleotidase, cytosolic IB

chr6_-_134680888 0.362 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr2_+_33213111 0.360 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr2_-_47986160 0.360 NM_001190274
FBXO11
F-box protein 11
chr3_+_23904086 0.359 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr4_+_90252990 0.359 NM_145715
TIGD2
tigger transposable element derived 2
chr4_-_83566246 0.358 HNRPDL
heterogeneous nuclear ribonucleoprotein D-like
chr2_+_214984705 0.358 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr16_-_20610078 0.357 NM_052956
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr6_+_4721825 0.356 CDYL
chromodomain protein, Y-like
chr3_-_153470022 0.354 LOC401093
hypothetical LOC401093
chr14_+_56927014 0.353 NM_001011713
NAA30
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr6_+_89847019 0.352 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr12_-_88573949 0.351 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chrX_-_33267646 0.350 NM_000109
DMD
dystrophin
chr16_+_24475129 0.350 RBBP6
retinoblastoma binding protein 6
chr3_+_192529567 0.349 NM_174908
NM_178335
CCDC50

coiled-coil domain containing 50

chr6_+_88026338 0.348 ZNF292
zinc finger protein 292
chr7_+_93388951 0.348 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr5_+_65258250 0.347 ERBB2IP
erbb2 interacting protein
chr2_+_201384880 0.347 BZW1
basic leucine zipper and W2 domains 1
chr1_+_87569959 0.347 LMO4
LIM domain only 4
chr6_+_45404031 0.346 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr15_-_48198697 0.346 NM_024837
ATP8B4
ATPase, class I, type 8B, member 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.19 4.03e-06 GO:0032501 multicellular organismal process
1.80 8.07e-06 GO:0007608 sensory perception of smell
1.74 1.26e-05 GO:0007606 sensory perception of chemical stimulus
1.15 1.67e-04 GO:0050896 response to stimulus
1.36 1.12e-03 GO:0050877 neurological system process
1.31 1.14e-03 GO:0003008 system process
1.44 4.97e-03 GO:0007600 sensory perception
1.32 7.00e-03 GO:0007399 nervous system development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.85 7.12e-07 GO:0004984 olfactory receptor activity