Motif ID: HAND1,2.p2

Z-value: 1.700


Transcription factors associated with HAND1,2.p2:

Gene SymbolEntrez IDGene Name
HAND1 9421 heart and neural crest derivatives expressed 1
HAND2 9464 heart and neural crest derivatives expressed 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HAND1chr5_-_1538380130.302.6e-01Click!
HAND2chr4_-_174687104-0.155.7e-01Click!


Activity profile for motif HAND1,2.p2.

activity profile for motif HAND1,2.p2


Sorted Z-values histogram for motif HAND1,2.p2

Sorted Z-values for motif HAND1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HAND1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_142270634 2.431 EPHB6
EPH receptor B6
chr19_+_55614006 2.426 NM_003121
 SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_+_557269 1.933


chr1_+_556968 1.925


chr12_+_119617060 1.918


chr2_+_204440753 1.697 NM_001037631
NM_005214
 CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr12_-_55917134 1.619 NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr19_+_458475 1.505 NM_033513
 C19orf20
chromosome 19 open reading frame 20
chr11_-_72063059 1.437 NM_002599
 PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr22_+_23333610 1.421 NM_001032365
 GGT1
gamma-glutamyltransferase 1
chr7_+_99654806 1.411 NM_024070
 PVRIG
poliovirus receptor related immunoglobulin domain containing
chr17_+_45617676 1.394


chr19_+_60279032 1.393 NM_133180
 EPS8L1
EPS8-like 1
chr1_+_200358594 1.327 NM_004767
 GPR37L1
G protein-coupled receptor 37 like 1
chrX_+_49718954 1.293 NM_000084
 CLCN5
chloride channel 5
chr7_+_5609416 1.271 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr3_+_46894239 1.215 NM_000316
 PTH1R
parathyroid hormone 1 receptor
chr11_-_117305277 1.211 NM_001077263
 TMPRSS13
transmembrane protease, serine 13
chr13_-_45640679 1.173 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr11_+_359723 1.164 NM_178537
 B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
1.64 8.91e-03 GO:0005615 extracellular space
1.63 6.61e-04 GO:0044421 extracellular region part
1.61 7.38e-09 GO:0005576 extracellular region
1.61 1.60e-04 GO:0005887 integral to plasma membrane
1.58 3.98e-04 GO:0031226 intrinsic to plasma membrane
1.48 1.03e-05 GO:0044459 plasma membrane part
1.32 1.08e-05 GO:0005886 plasma membrane
1.31 2.07e-05 GO:0071944 cell periphery
1.22 8.36e-04 GO:0031224 intrinsic to membrane
1.22 2.17e-03 GO:0016021 integral to membrane
1.21 1.97e-04 GO:0044425 membrane part
1.17 9.20e-04 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
13.68 2.97e-02 GO:0032052 bile acid binding
7.89 2.54e-02 GO:0048019 receptor antagonist activity
7.33 4.23e-02 GO:0030547 receptor inhibitor activity