Motif ID: NKX6-1,2.p2

Z-value: 1.259


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-2chr10_-_134449467-0.312.5e-01Click!
NKX6-1chr4_-_856384100.214.4e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_21375258 2.631 NM_000605
 IFNA2
interferon, alpha 2
chr5_-_58331515 2.270 NM_001197223
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr3_-_79899748 1.861 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr14_+_62740878 1.638 NM_020663
 RHOJ
ras homolog gene family, member J
chr13_+_23042722 1.516 NM_148957
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr6_-_128263868 1.452 NM_001010923
NM_001164685
 THEMIS

thymocyte selection associated

chr4_+_70928718 1.204 NM_000200
 HTN3
histatin 3
chr8_-_82769761 1.181 NM_001010893
 SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr15_+_34720097 1.147 NM_032499
 C15orf41
chromosome 15 open reading frame 41
chr20_+_23293020 1.115 NM_022482
 GZF1
GDNF-inducible zinc finger protein 1
chr2_+_191222077 1.051 NM_005966
 NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr12_+_32546243 1.044 NM_139241
 FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_+_130014957 1.033 RAB7A
RAB7A, member RAS oncogene family
chr3_-_121065112 0.995


chr1_+_245835478 0.991 NM_001001914
 OR2G3
olfactory receptor, family 2, subfamily G, member 3
chr6_-_66346417 0.988 NM_198283
 EYS
eyes shut homolog (Drosophila)
chr14_-_63076155 0.975 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr20_+_11846536 0.966 NM_014962
 BTBD3
BTB (POZ) domain containing 3
chr12_-_131816604 0.958 ANKLE2
ankyrin repeat and LEM domain containing 2
chr6_+_118976134 0.956 NM_002667
 PLN
phospholamban

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.39 1.50e-07 GO:0007606 sensory perception of chemical stimulus
2.30 1.47e-05 GO:0007608 sensory perception of smell
1.83 9.63e-05 GO:0007600 sensory perception
1.57 1.12e-03 GO:0050877 neurological system process
1.52 4.04e-04 GO:0003008 system process
1.19 2.39e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.20 4.45e-02 GO:0045111 intermediate filament cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
2.32 4.65e-06 GO:0004984 olfactory receptor activity
1.72 4.26e-04 GO:0004930 G-protein coupled receptor activity
1.49 7.53e-03 GO:0004888 transmembrane receptor activity