Motif ID: HMGA1,2.p2

Z-value: 3.780


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HMGA1chr6_+_34313347-0.731.4e-03Click!
HMGA2chr12_+_645048350.224.2e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_215967442 6.417 FN1
fibronectin 1
chr2_-_47969350 5.688 NM_025133
 FBXO11
F-box protein 11
chr3_-_114176401 5.270 NM_138806
NM_138939
NM_138940
NM_170780
 CD200R1



CD200 receptor 1



chr13_-_45577144 4.847 NM_001872
NM_016413
 CPB2

carboxypeptidase B2 (plasma)

chr2_+_228064531 4.591 AGFG1
ArfGAP with FG repeats 1
chr21_-_26345294 4.449


chr9_-_21218132 4.381 NM_021268
 IFNA17
interferon, alpha 17
chr3_-_56784634 4.301 NM_001128616
 ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr13_+_107753764 4.208


chr9_-_106407728 4.174 NM_001004481
 OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr9_-_21132143 4.044 NM_002177
 IFNW1
interferon, omega 1
chr5_-_58607673 3.910 NM_001197220
 PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_+_16397617 3.798 NM_145764
 MGST1
microsomal glutathione S-transferase 1
chr6_+_153113624 3.591 NM_003381
NM_194435
 VIP

vasoactive intestinal peptide

chr4_+_176076083 3.510 NM_001130703
NM_001130704
NM_001130705
NM_014269
 ADAM29



ADAM metallopeptidase domain 29



chr12_-_66905802 3.431 NM_018402
 IL26
interleukin 26
chr2_+_108751033 3.402 RANBP2
RAN binding protein 2
chr1_-_21310462 3.381 NM_003760
 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr18_-_65766068 3.275 CD226
CD226 molecule
chr11_+_55776251 3.218 NM_001004747
 OR5T3
olfactory receptor, family 5, subfamily T, member 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.16 3.16e-52 GO:0007608 sensory perception of smell
3.02 6.86e-52 GO:0007606 sensory perception of chemical stimulus
2.16 7.15e-33 GO:0007600 sensory perception
1.68 8.28e-20 GO:0050877 neurological system process
1.55 5.21e-17 GO:0003008 system process
1.14 3.22e-03 GO:0032501 multicellular organismal process
1.11 1.41e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.23 3.42e-09 GO:0071944 cell periphery
1.23 6.09e-09 GO:0005886 plasma membrane
1.11 1.76e-02 GO:0016021 integral to membrane
1.11 2.87e-02 GO:0031224 intrinsic to membrane
1.10 7.03e-03 GO:0044425 membrane part
1.08 3.34e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
5.67 1.21e-02 GO:0005132 interferon-alpha/beta receptor binding
3.28 2.02e-55 GO:0004984 olfactory receptor activity
2.18 4.59e-36 GO:0004930 G-protein coupled receptor activity
1.76 1.56e-24 GO:0004888 transmembrane receptor activity
1.54 1.55e-17 GO:0004872 receptor activity
1.42 3.72e-13 GO:0004871 signal transducer activity
1.42 3.72e-13 GO:0060089 molecular transducer activity
1.38 2.90e-02 GO:0005509 calcium ion binding