Motif ID: NHLH1,2.p2

Z-value: 1.933


Transcription factors associated with NHLH1,2.p2:

Gene SymbolEntrez IDGene Name
NHLH1 4807 nescient helix loop helix 1
NHLH2 4808 nescient helix loop helix 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NHLH2chr1_-_1161852150.391.3e-01Click!
NHLH1chr1_+_158603480-0.126.5e-01Click!


Activity profile for motif NHLH1,2.p2.

activity profile for motif NHLH1,2.p2


Sorted Z-values histogram for motif NHLH1,2.p2

Sorted Z-values for motif NHLH1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NHLH1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_17304707 5.010 NM_001621
AHR
aryl hydrocarbon receptor
chr2_+_109112428 2.893 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr17_-_36533903 2.826 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr3_-_62835601 2.701


chr2_+_202949289 2.695 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr2_-_6923215 2.359 NM_207315
CMPK2
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr2_+_46779827 2.252 NM_144949
SOCS5
suppressor of cytokine signaling 5
chr4_+_144325533 2.244 USP38
ubiquitin specific peptidase 38
chr2_+_208979800 2.137 NM_005048
PTH2R
parathyroid hormone 2 receptor
chr4_+_144325502 2.081 NM_032557
USP38
ubiquitin specific peptidase 38
chr17_+_36665161 2.010 NM_030975
KRTAP9-9
keratin associated protein 9-9
chr17_+_36636404 1.990 NM_031961
KRTAP9-2
keratin associated protein 9-2
chr6_+_124166767 1.970 NM_001040214
NM_153355
NKAIN2

Na+/K+ transporting ATPase interacting 2

chr4_+_95592067 1.967 PDLIM5
PDZ and LIM domain 5
chr4_+_95592030 1.933 NM_001011513
NM_001011515
NM_001011516
NM_006457
PDLIM5



PDZ and LIM domain 5



chr3_-_121550767 1.916 NM_001099678
LRRC58
leucine rich repeat containing 58
chr17_+_36659464 1.743 NM_033191
KRTAP9-4
keratin associated protein 9-4
chr13_+_77170470 1.718 NM_001040153
SLAIN1
SLAIN motif family, member 1
chr17_+_36642240 1.632 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr17_-_36570508 1.604 NM_032524
KRTAP4-4
keratin associated protein 4-4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
2.43 3.50e-02 GO:0043242 negative regulation of protein complex disassembly
2.06 4.07e-02 GO:0030832 regulation of actin filament length
1.48 3.21e-02 GO:0032535 regulation of cellular component size
1.30 2.30e-02 GO:0051128 regulation of cellular component organization
1.24 3.85e-03 GO:0007399 nervous system development
1.23 4.94e-03 GO:0023051 regulation of signaling
1.21 7.69e-03 GO:0006464 protein modification process
1.10 6.29e-03 GO:0044237 cellular metabolic process
1.08 2.21e-02 GO:0050794 regulation of cellular process
1.06 2.24e-04 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
1.74 1.58e-03 GO:0005912 adherens junction
1.74 4.41e-02 GO:0005924 cell-substrate adherens junction
1.60 2.97e-02 GO:0070161 anchoring junction
1.13 1.17e-14 GO:0005737 cytoplasm
1.11 5.26e-05 GO:0044444 cytoplasmic part
1.09 3.86e-15 GO:0044424 intracellular part
1.09 6.21e-15 GO:0005622 intracellular
1.08 2.15e-06 GO:0043226 organelle
1.08 2.86e-06 GO:0043229 intracellular organelle
1.03 2.82e-03 GO:0044464 cell part
1.03 2.98e-03 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
3.18 5.32e-03 GO:0004675 transmembrane receptor protein serine/threonine kinase activity
1.63 3.19e-02 GO:0004721 phosphoprotein phosphatase activity
1.28 4.57e-02 GO:0019899 enzyme binding
1.09 1.17e-04 GO:0005515 protein binding
1.09 3.58e-02 GO:0003824 catalytic activity
1.05 1.72e-03 GO:0005488 binding