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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: EGR1..3.p2

Z-value: 2.423

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_60663842	5.184	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr2_+_109112428	4.720	NM_001099289	SH3RF3	SH3 domain containing ring finger 3
chr12_+_6907646	3.991	NM_001940	ATN1	atrophin 1
chr2_+_191222077	3.701	NM_005966	NAB1	NGFI-A binding protein 1 (EGR1 binding protein 1)
chr3_-_88190737	3.522	NM_001008390 NM_003663	CGGBP1	CGG triplet repeat binding protein 1
chr12_+_50271283	3.197	NM_014191	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr13_+_19430906	3.044	NM_001190965	ZMYM2	zinc finger, MYM-type 2
chr5_+_139473873	2.793	NM_005859	PURA	purine-rich element binding protein A
chr22_+_49459935	2.652	NM_001080420	SHANK3	SH3 and multiple ankyrin repeat domains 3
chr13_+_19430881	2.541		ZMYM2	zinc finger, MYM-type 2
chr8_+_16929116	2.524	NM_181723	EFHA2	EF-hand domain family, member A2
chr14_+_70444191	2.475		PCNX	pecanex homolog (Drosophila)
chr13_+_19430788	2.286	NM_003453 NM_197968 NM_001190964	ZMYM2	zinc finger, MYM-type 2
chr17_+_2443652	2.284	NM_000430	PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr21_+_16024241	2.150	NM_013396	USP25	ubiquitin specific peptidase 25
chr6_+_36272506	2.131	NM_015695	BRPF3	bromodomain and PHD finger containing, 3
chr17_+_11864841	2.055	NM_003010	MAP2K4	mitogen-activated protein kinase kinase 4
chr10_+_98582005	1.962	NM_001170765 NM_001170766	LCOR	ligand dependent nuclear receptor corepressor
chr17_+_2443983	1.914		PAFAH1B1	platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr19_+_57492236	1.903	NM_144684	ZNF480	zinc finger protein 480
chr5_+_122875691	1.877	NM_001031812 NM_001044722 NM_001044723 NM_004384	CSNK1G3	casein kinase 1, gamma 3
chr12_+_19484044	1.861		AEBP2	AE binding protein 2
chr12_+_26003218	1.817	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr2_+_104838177	1.770	NM_006236	POU3F3	POU class 3 homeobox 3
chr10_-_128884411	1.751	NM_001039762	FAM196A	family with sequence similarity 196, member A
chr8_+_94998258	1.747	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr2_+_235525355	1.723	NM_014521	SH3BP4	SH3-domain binding protein 4
chr13_-_40533072	1.705		ELF1	E74-like factor 1 (ets domain transcription factor)
chr6_-_151754337	1.701	NM_020861	ZBTB2	zinc finger and BTB domain containing 2
chr10_+_49184658	1.700		MAPK8	mitogen-activated protein kinase 8
chr6_-_36272951	1.700
chr10_+_89613399	1.688		PTEN	phosphatase and tensin homolog
chr13_+_75108450	1.656		LMO7	LIM domain 7
chr10_+_93160066	1.611	NM_173497 NM_182765	HECTD2	HECT domain containing 2
chr4_+_38545741	1.535	NM_138389	FAM114A1	family with sequence similarity 114, member A1
chr11_+_113815317	1.534	NM_015523	REXO2	REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr16_+_51722285	1.526		CHD9	chromodomain helicase DNA binding protein 9
chr4_+_108965167	1.521	NM_001136258	SGMS2	sphingomyelin synthase 2
chr12_+_6745947	1.519		PTMS	parathymosin
chr12_+_104248769	1.515		C12orf75	chromosome 12 open reading frame 75
chr15_+_65145248	1.513	NM_005902	SMAD3	SMAD family member 3
chr10_-_108914277	1.512	NM_001013031 NM_052918	SORCS1	sortilin-related VPS10 domain containing receptor 1
chr19_+_16296734	1.487		KLF2	Kruppel-like factor 2 (lung)
chr12_+_6745835	1.484		PTMS	parathymosin
chr9_+_115678365	1.482	NM_133374	ZNF618	zinc finger protein 618
chr14_+_51188289	1.480	NM_152330	FRMD6	FERM domain containing 6
chr3_+_58452560	1.472	NM_001128214	KCTD6	potassium channel tetramerisation domain containing 6
chr14_+_44622916	1.459	NM_017922	PRPF39	PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae)
chr19_+_49943773	1.441	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr10_+_89613071	1.437	NM_000314	PTEN	phosphatase and tensin homolog
chr9_+_130354490	1.424	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr9_+_127549437	1.401	NM_006195	PBX3	pre-B-cell leukemia homeobox 3
chr2_+_54536780	1.387	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr7_+_39956480	1.378	NM_003718 NM_031267	CDK13	cyclin-dependent kinase 13
chr3_+_73128629	1.374		PPP4R2	protein phosphatase 4, regulatory subunit 2
chrX_-_152592450	1.371		PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr2_+_181553333	1.362	NM_182678 NM_006357	UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr2_+_135392879	1.355		CCNT2	cyclin T2
chr12_+_6745729	1.350	NM_002824	PTMS	parathymosin
chr13_+_77170470	1.347	NM_001040153	SLAIN1	SLAIN motif family, member 1
chr7_+_39956633	1.335		CDK13	cyclin-dependent kinase 13
chr10_+_35665614	1.333	NM_145012	CCNY	cyclin Y
chr2_-_210744158	1.324	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr3_+_73128667	1.323		PPP4R2	protein phosphatase 4, regulatory subunit 2
chr2_+_135392857	1.314	NM_001241 NM_058241	CCNT2	cyclin T2
chr10_+_116571485	1.305	NM_001135051 NM_020940	FAM160B1	family with sequence similarity 160, member B1
chr14_+_85069217	1.302
chr10_-_89613173	1.297	NM_001126049	KLLN	killin, p53-regulated DNA replication inhibitor
chr6_+_167970334	1.295	NM_001040000	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
chr1_+_78126787	1.277	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr10_+_111757867	1.275		ADD3	adducin 3 (gamma)
chr13_+_96884316	1.244	NM_021033	RAP2A	RAP2A, member of RAS oncogene family
chr1_+_67168470	1.242	NM_001077701 NM_001077704	MIER1	mesoderm induction early response 1 homolog (Xenopus laevis)
chr13_+_96884682	1.238		RAP2A	RAP2A, member of RAS oncogene family
chr14_+_59785739	1.236		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr8_+_26204997	1.232		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr10_+_93160033	1.222
chr14_-_99016917	1.217		SETD3	SET domain containing 3
chr3_+_73128771	1.210	NM_174907	PPP4R2	protein phosphatase 4, regulatory subunit 2
chr1_-_9111674	1.206	NM_024980	GPR157	G protein-coupled receptor 157
chr21_+_16024157	1.200		USP25	ubiquitin specific peptidase 25
chr14_+_89934358	1.196	NM_001166106	CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr4_+_3046034	1.195	NM_002111	HTT	huntingtin
chr3_-_15875932	1.194	NM_015199	ANKRD28	ankyrin repeat domain 28
chr2_+_149119029	1.184	NM_015630	EPC2	enhancer of polycomb homolog 2 (Drosophila)
chr19_+_16296632	1.183	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr14_-_99016866	1.177		SETD3	SET domain containing 3
chr1_+_70459686	1.170		SRSF11	serine/arginine-rich splicing factor 11
chr1_+_35507145	1.150	NM_005095	ZMYM4	zinc finger, MYM-type 4
chr14_-_99016833	1.146		SETD3	SET domain containing 3
chr11_-_94603857	1.137	NM_144665	SESN3	sestrin 3
chr4_+_48038259	1.127	NM_020846	SLAIN2	SLAIN motif family, member 2
chr12_+_129388543	1.123		PIWIL1	piwi-like 1 (Drosophila)
chr14_+_59786047	1.122		PPM1A	protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr6_+_89848229	1.120		PNRC1	proline-rich nuclear receptor coactivator 1
chr12_+_19483578	1.117	NM_001114176 NM_153207	AEBP2	AE binding protein 2
chr4_+_77391876	1.106	NM_001136570	FAM47E	family with sequence similarity 47, member E
chr2_+_181553613	1.094		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr16_+_68157611	1.092		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr7_+_33135376	1.090	NM_001033604 NM_001033605 NM_014451 NM_198428	BBS9	Bardet-Biedl syndrome 9
chr10_+_102749597	1.085		LZTS2	leucine zipper, putative tumor suppressor 2
chr1_+_26895108	1.079	NM_006015 NM_139135	ARID1A	AT rich interactive domain 1A (SWI-like)
chr2_+_203901160	1.073	NM_005759	ABI2	abl-interactor 2
chr11_+_12355600	1.071	NM_018222	PARVA	parvin, alpha
chr6_+_21701942	1.062	NM_003107	SOX4	SRY (sex determining region Y)-box 4
chr12_+_19484387	1.052		AEBP2	AE binding protein 2
chr14_-_60022487	1.048	NM_174978	C14orf39	chromosome 14 open reading frame 39
chr15_+_36332258	1.047	NM_152594	SPRED1	sprouty-related, EVH1 domain containing 1
chr3_+_50687675	1.038	NM_004947	DOCK3	dedicator of cytokinesis 3
chr10_+_89613347	1.035		PTEN	phosphatase and tensin homolog
chr5_-_59225377	1.021	NM_001104631	PDE4D	phosphodiesterase 4D, cAMP-specific
chr12_+_109203412	1.018	NM_001135765 NM_001681 NM_170665	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr1_-_240754620	1.017	NM_152666	PLD5	phospholipase D family, member 5
chr7_+_77005287	1.017	NM_001131008 NM_001131009	PTPN12	protein tyrosine phosphatase, non-receptor type 12
chr12_+_104248520	1.013	NM_001145199	C12orf75	chromosome 12 open reading frame 75
chr1_+_70459592	1.011		SRSF11	serine/arginine-rich splicing factor 11
chr8_+_59628281	1.007	NM_001007067 NM_001007068 NM_001007069 NM_001007070 NM_005625	SDCBP	syndecan binding protein (syntenin)
chr6_+_99389300	1.006	NM_005604	POU3F2	POU class 3 homeobox 2
chr10_+_94598204	1.004	NM_019053	EXOC6	exocyst complex component 6
chr3_+_180348818	0.999	NM_006218	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr20_+_13150417	0.999	NM_080826	ISM1	isthmin 1 homolog (zebrafish)
chr6_+_149680747	0.999		TAB2	TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr5_+_102622305	0.997	NM_033211	C5orf30	chromosome 5 open reading frame 30
chr1_+_181259317	0.995
chr13_+_113193395	0.994		TMCO3	transmembrane and coiled-coil domains 3
chr6_-_94185780	0.994	NM_004440	EPHA7	EPH receptor A7
chr10_+_23768203	0.992	NM_001145373	OTUD1	OTU domain containing 1
chr15_-_71712605	0.989		NPTN	neuroplastin
chr1_+_183281173	0.978	NM_007212	RNF2	ring finger protein 2
chr4_-_35922288	0.977	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_37862398	0.974
chr14_-_99016959	0.966	NM_032233 NM_199123	SETD3	SET domain containing 3
chr10_-_102663070	0.958
chr2_+_206847658	0.958	NM_020923	ZDBF2	zinc finger, DBF-type containing 2
chr17_+_44927591	0.957	NM_002507	NGFR	nerve growth factor receptor
chr17_+_57909979	0.956	NM_001112707 NM_006852	TLK2	tousled-like kinase 2
chr2_+_228045121	0.954	NM_001135187 NM_001135188 NM_001135189 NM_004504	AGFG1	ArfGAP with FG repeats 1
chr10_+_35665403	0.952		CCNY	cyclin Y
chr1_-_99242765	0.952	NM_001010861 NM_001037317	LPPR5	lipid phosphate phosphatase-related protein type 5
chr8_+_59628352	0.949		SDCBP	syndecan binding protein (syntenin)
chr12_-_123023052	0.946	NM_025140	CCDC92	coiled-coil domain containing 92
chr15_+_71131877	0.942	NM_001172623 NM_001172624 NM_002499	NEO1	neogenin 1
chr6_+_89847183	0.939		PNRC1	proline-rich nuclear receptor coactivator 1
chr13_-_113192986	0.932	NM_001014283	DCUN1D2	DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae)
chr18_+_12397894	0.928	NM_001142405 NM_006553	SLMO1	slowmo homolog 1 (Drosophila)
chr9_-_85622366	0.928	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr7_+_79602023	0.926	NM_002069	GNAI1	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_+_76368462	0.922		SENP6	SUMO1/sentrin specific peptidase 6
chrX_-_152591936	0.919	NM_001135740	PNCK	pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr8_+_55533047	0.917	NM_022454	SOX17	SRY (sex determining region Y)-box 17
chr2_+_27504987	0.915		NRBP1	nuclear receptor binding protein 1
chr2_+_85051687	0.914	NM_020122	KCMF1	potassium channel modulatory factor 1
chr20_-_48980858	0.911	NM_015339 NM_181442	ADNP	activity-dependent neuroprotector homeobox
chr4_-_38342824	0.910		FLJ13197	hypothetical FLJ13197
chr15_+_37660568	0.904	NM_003246	THBS1	thrombospondin 1
chr4_+_81406765	0.903	NM_004464 NM_033143	FGF5	fibroblast growth factor 5
chr13_+_40533622	0.899	NM_007187	WBP4	WW domain binding protein 4 (formin binding protein 21)
chr7_-_130069399	0.897	NM_138693	KLF14	Kruppel-like factor 14
chr17_+_44340852	0.895		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr12_+_55769189	0.891		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr11_+_117812282	0.888	NM_001197104 NM_005933	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
chr3_+_23822481	0.887		UBE2E1	ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr14_-_64416307	0.880		SPTB	spectrin, beta, erythrocytic
chr15_-_71712711	0.867	NM_001161363 NM_001161364 NM_012428 NM_017455	NPTN	neuroplastin
chr14_+_66777578	0.866	NM_022474	MPP5	membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr2_+_192251105	0.863	NM_001031716	OBFC2A	oligonucleotide/oligosaccharide-binding fold containing 2A
chr3_+_171558143	0.858	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr17_+_5126275	0.853	NM_001083585 NM_004703	RABEP1	rabaptin, RAB GTPase binding effector protein 1
chr17_+_64020120	0.853	NM_002734 NM_212472	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr10_+_171410	0.851		ZMYND11	zinc finger, MYND-type containing 11
chr17_+_44340828	0.851		UBE2Z	ubiquitin-conjugating enzyme E2Z
chr3_-_24511456	0.846		THRB	thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr5_-_114660139	0.844	NM_001040440	CCDC112	coiled-coil domain containing 112
chr12_+_102982365	0.841	NM_013320	HCFC2	host cell factor C2
chr8_-_75396016	0.841	NM_020647	JPH1	junctophilin 1
chr6_-_110607496	0.835		WASF1	WAS protein family, member 1
chr7_+_35807369	0.832		SEPT7	septin 7
chr17_+_46151918	0.830	NM_006107 NM_016424	LUC7L3	LUC7-like 3 (S. cerevisiae)
chr1_+_35507197	0.827		ZMYM4	zinc finger, MYM-type 4
chr3_+_148610516	0.824		ZIC1	Zic family member 1 (odd-paired homolog, Drosophila)
chr13_+_113193308	0.817	NM_017905	TMCO3	transmembrane and coiled-coil domains 3
chr13_+_31318828	0.812		EEF1DP3	eukaryotic translation elongation factor 1 delta pseudogene 3
chr9_+_102229283	0.811	NM_001198807 NM_080655 NM_001198805	C9orf30	chromosome 9 open reading frame 30
chr2_+_181553783	0.811		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr8_-_144313053	0.810		LY6H	lymphocyte antigen 6 complex, locus H
chr12_-_123023312	0.805		CCDC92	coiled-coil domain containing 92
chr6_+_37895570	0.799		ZFAND3	zinc finger, AN1-type domain 3
chr11_-_16992524	0.796	NM_175058	PLEKHA7	pleckstrin homology domain containing, family A member 7
chr18_+_12298189	0.796		TUBB6	tubulin, beta 6
chr14_+_32478209	0.790	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr4_+_89147821	0.790	NM_000297	PKD2	polycystic kidney disease 2 (autosomal dominant)
chr1_+_93686154	0.788	NM_001024948 NM_001164473 NM_017737	FNBP1L	formin binding protein 1-like
chr17_+_64020155	0.788		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr1_+_13948448	0.788	NM_001007257	PRDM2	PR domain containing 2, with ZNF domain
chr6_+_76367944	0.786		SENP6	SUMO1/sentrin specific peptidase 6
chr7_+_35807139	0.785	NM_001011553 NM_001788	SEPT7	septin 7
chr2_+_181554048	0.784		UBE2E3	ubiquitin-conjugating enzyme E2E 3 (UBC4/5 homolog, yeast)
chr4_-_71789843	0.783		LOC641510	hypothetical LOC641510
chr10_+_102662675	0.781		FAM178A	family with sequence similarity 178, member A
chr12_+_55769153	0.780		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.26	2.30e-16	GO:0044260	cellular macromolecule metabolic process
1.11	6.01e-15	GO:0009987	cellular process
1.17	7.60e-14	GO:0050794	regulation of cellular process
1.18	2.89e-13	GO:0044237	cellular metabolic process
1.39	1.07e-12	GO:0006464	protein modification process
1.16	2.05e-12	GO:0050789	regulation of biological process
1.21	6.37e-12	GO:0043170	macromolecule metabolic process
1.36	2.24e-11	GO:0043412	macromolecule modification
1.14	3.33e-11	GO:0065007	biological regulation
1.41	7.34e-11	GO:0007399	nervous system development
1.23	9.94e-11	GO:0019222	regulation of metabolic process
1.24	7.41e-10	GO:0031323	regulation of cellular metabolic process
1.29	1.46e-09	GO:0044267	cellular protein metabolic process
1.37	2.10e-09	GO:0023051	regulation of signaling
1.24	2.47e-09	GO:0060255	regulation of macromolecule metabolic process
1.29	7.30e-09	GO:0048519	negative regulation of biological process
1.74	7.63e-09	GO:0007409	axonogenesis
1.15	1.08e-08	GO:0044238	primary metabolic process
1.67	1.34e-08	GO:0048858	cell projection morphogenesis
1.71	1.43e-08	GO:0048812	neuron projection morphogenesis
1.72	1.52e-08	GO:0048667	cell morphogenesis involved in neuron differentiation
1.22	2.17e-08	GO:0080090	regulation of primary metabolic process
1.30	2.59e-08	GO:0048523	negative regulation of cellular process
1.66	2.93e-08	GO:0032990	cell part morphogenesis
1.13	3.00e-08	GO:0008152	metabolic process
1.58	3.05e-08	GO:0030030	cell projection organization
1.65	5.37e-08	GO:0000904	cell morphogenesis involved in differentiation
1.26	5.60e-08	GO:0071842	cellular component organization at cellular level
1.47	6.44e-08	GO:0022008	neurogenesis
1.36	7.64e-08	GO:0009653	anatomical structure morphogenesis
1.26	1.06e-07	GO:0010468	regulation of gene expression
1.36	1.45e-07	GO:0009966	regulation of signal transduction
1.64	1.74e-07	GO:0031175	neuron projection development
1.57	2.20e-07	GO:0000902	cell morphogenesis
1.78	2.33e-07	GO:0007411	axon guidance
1.47	3.70e-07	GO:0048699	generation of neurons
1.54	6.84e-07	GO:0032989	cellular component morphogenesis
1.21	8.14e-07	GO:0016043	cellular component organization
1.28	8.59e-07	GO:0030154	cell differentiation
1.43	8.76e-07	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.28	1.27e-06	GO:0048869	cellular developmental process
1.24	1.60e-06	GO:0071841	cellular component organization or biogenesis at cellular level
1.25	2.50e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.23	2.63e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21	6.48e-06	GO:0019538	protein metabolic process
1.20	7.13e-06	GO:0071840	cellular component organization or biogenesis
1.25	7.90e-06	GO:0051252	regulation of RNA metabolic process
1.41	7.94e-06	GO:0048468	cell development
1.18	9.81e-06	GO:0032502	developmental process
1.53	1.29e-05	GO:0048666	neuron development
1.24	1.35e-05	GO:0048522	positive regulation of cellular process
1.23	1.92e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.44	2.59e-05	GO:0016192	vesicle-mediated transport
1.22	3.87e-05	GO:0031326	regulation of cellular biosynthetic process
1.21	5.36e-05	GO:0009889	regulation of biosynthetic process
1.66	5.71e-05	GO:0070647	protein modification by small protein conjugation or removal
1.32	8.24e-05	GO:0051641	cellular localization
1.18	8.68e-05	GO:0007275	multicellular organismal development
1.24	9.64e-05	GO:0006355	regulation of transcription, DNA-dependent
1.33	9.71e-05	GO:0031325	positive regulation of cellular metabolic process
1.34	1.25e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.38	1.40e-04	GO:0050793	regulation of developmental process
1.70	1.59e-04	GO:0032446	protein modification by small protein conjugation
1.41	1.85e-04	GO:0046907	intracellular transport
1.46	2.40e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.47	2.71e-04	GO:0010629	negative regulation of gene expression
1.41	2.82e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	3.15e-04	GO:0009893	positive regulation of metabolic process
1.26	3.23e-04	GO:0016070	RNA metabolic process
1.43	3.52e-04	GO:0010628	positive regulation of gene expression
1.35	4.05e-04	GO:0032268	regulation of cellular protein metabolic process
1.34	4.21e-04	GO:0010646	regulation of cell communication
1.43	4.56e-04	GO:0051254	positive regulation of RNA metabolic process
1.20	5.23e-04	GO:0048518	positive regulation of biological process
1.20	5.31e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	6.85e-04	GO:0051649	establishment of localization in cell
1.39	7.81e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.18	8.29e-04	GO:0048856	anatomical structure development
1.37	9.41e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.16	1.11e-03	GO:0023052	signaling
1.41	1.18e-03	GO:0030182	neuron differentiation
1.46	1.48e-03	GO:0051253	negative regulation of RNA metabolic process
1.36	1.56e-03	GO:0009891	positive regulation of biosynthetic process
1.39	1.92e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.49	2.60e-03	GO:0061024	membrane organization
1.17	2.61e-03	GO:0006807	nitrogen compound metabolic process
2.07	2.63e-03	GO:0040029	regulation of gene expression, epigenetic
1.18	2.92e-03	GO:0051171	regulation of nitrogen compound metabolic process
1.32	2.95e-03	GO:0006793	phosphorus metabolic process
1.32	2.95e-03	GO:0006796	phosphate metabolic process
1.41	2.97e-03	GO:0007167	enzyme linked receptor protein signaling pathway
1.49	3.43e-03	GO:0016044	cellular membrane organization
1.24	4.12e-03	GO:0006996	organelle organization
1.31	4.12e-03	GO:0051246	regulation of protein metabolic process
1.23	4.38e-03	GO:0048583	regulation of response to stimulus
1.17	4.39e-03	GO:0034641	cellular nitrogen compound metabolic process
1.41	4.45e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.26	4.76e-03	GO:0065009	regulation of molecular function
1.65	4.92e-03	GO:0030036	actin cytoskeleton organization
1.37	5.21e-03	GO:2000026	regulation of multicellular organismal development
1.44	5.48e-03	GO:0045892	negative regulation of transcription, DNA-dependent
1.45	5.48e-03	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.27	6.02e-03	GO:0035556	intracellular signal transduction
1.44	6.21e-03	GO:0016071	mRNA metabolic process
1.86	6.37e-03	GO:0006184	GTP catabolic process
1.29	7.85e-03	GO:0044248	cellular catabolic process
1.16	8.41e-03	GO:0007165	signal transduction
1.17	8.53e-03	GO:0048731	system development
1.38	8.95e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.60	9.41e-03	GO:0010608	posttranscriptional regulation of gene expression
1.37	9.62e-03	GO:0009890	negative regulation of biosynthetic process
2.18	9.85e-03	GO:0007173	epidermal growth factor receptor signaling pathway
1.38	9.98e-03	GO:0045595	regulation of cell differentiation
1.32	1.23e-02	GO:0010605	negative regulation of macromolecule metabolic process
1.61	1.31e-02	GO:0016567	protein ubiquitination
1.38	1.35e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.20	1.36e-02	GO:0090304	nucleic acid metabolic process
1.49	1.65e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.62	1.65e-02	GO:0072523	purine-containing compound catabolic process
1.30	1.70e-02	GO:0009892	negative regulation of metabolic process
1.62	2.17e-02	GO:0006195	purine nucleotide catabolic process
1.30	2.31e-02	GO:0032879	regulation of localization
1.31	2.55e-02	GO:0006351	transcription, DNA-dependent
1.49	2.72e-02	GO:0016568	chromatin modification
1.41	3.12e-02	GO:0044265	cellular macromolecule catabolic process
1.32	3.22e-02	GO:0051128	regulation of cellular component organization
1.38	3.32e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.63	3.58e-02	GO:0048011	nerve growth factor receptor signaling pathway
2.19	3.74e-02	GO:0016458	gene silencing
1.49	4.02e-02	GO:0018193	peptidyl-amino acid modification
1.60	4.09e-02	GO:0006897	endocytosis
1.60	4.09e-02	GO:0010324	membrane invagination
3.30	4.18e-02	GO:0008333	endosome to lysosome transport
1.35	4.35e-02	GO:0019220	regulation of phosphate metabolic process
1.35	4.35e-02	GO:0051174	regulation of phosphorus metabolic process
1.25	4.63e-02	GO:0051239	regulation of multicellular organismal process
1.42	4.83e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.30	4.92e-02	GO:0031324	negative regulation of cellular metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	6.82e-45	GO:0005622	intracellular
1.16	1.75e-44	GO:0044424	intracellular part
1.16	6.77e-27	GO:0043229	intracellular organelle
1.16	7.55e-27	GO:0043226	organelle
1.19	2.24e-26	GO:0005737	cytoplasm
1.16	1.55e-20	GO:0043227	membrane-bounded organelle
1.16	1.63e-20	GO:0043231	intracellular membrane-bounded organelle
1.23	9.64e-20	GO:0005634	nucleus
1.17	1.74e-11	GO:0044444	cytoplasmic part
1.32	8.70e-11	GO:0005829	cytosol
1.05	1.56e-09	GO:0044464	cell part
1.05	1.68e-09	GO:0005623	cell
1.54	1.68e-07	GO:0030054	cell junction
1.22	2.45e-07	GO:0043234	protein complex
1.97	5.40e-07	GO:0031252	cell leading edge
1.14	7.90e-07	GO:0044446	intracellular organelle part
1.14	2.17e-06	GO:0044422	organelle part
1.25	2.26e-06	GO:0044428	nuclear part
1.32	3.30e-06	GO:0005654	nucleoplasm
1.27	6.15e-06	GO:0031981	nuclear lumen
2.36	6.31e-06	GO:0030027	lamellipodium
1.95	2.90e-05	GO:0005912	adherens junction
2.64	3.71e-05	GO:0035770	RNA granule
1.56	3.83e-05	GO:0045202	synapse
1.17	5.55e-05	GO:0032991	macromolecular complex
1.22	5.86e-05	GO:0070013	intracellular organelle lumen
2.20	7.37e-05	GO:0016585	chromatin remodeling complex
1.21	1.18e-04	GO:0031974	membrane-enclosed lumen
1.21	1.22e-04	GO:0043233	organelle lumen
1.26	2.43e-04	GO:0005856	cytoskeleton
1.82	3.28e-04	GO:0070161	anchoring junction
1.36	3.59e-04	GO:0031982	vesicle
1.37	3.92e-04	GO:0031410	cytoplasmic vesicle
1.66	4.19e-04	GO:0005667	transcription factor complex
2.01	4.34e-04	GO:0030055	cell-substrate junction
1.37	8.89e-04	GO:0044451	nucleoplasm part
1.18	9.27e-04	GO:0043228	non-membrane-bounded organelle
1.18	9.27e-04	GO:0043232	intracellular non-membrane-bounded organelle
1.57	1.33e-03	GO:0015629	actin cytoskeleton
1.35	1.87e-03	GO:0016023	cytoplasmic membrane-bounded vesicle
1.35	1.98e-03	GO:0031988	membrane-bounded vesicle
1.68	2.65e-03	GO:0030135	coated vesicle
1.95	2.66e-03	GO:0005924	cell-substrate adherens junction
1.75	2.84e-03	GO:0030136	clathrin-coated vesicle
1.31	3.09e-03	GO:0042995	cell projection
2.08	4.16e-03	GO:0014069	postsynaptic density
1.95	4.40e-03	GO:0005925	focal adhesion
1.22	5.29e-03	GO:0012505	endomembrane system
1.53	5.39e-03	GO:0044456	synapse part
1.81	5.71e-03	GO:0005938	cell cortex
2.12	1.21e-02	GO:0030117	membrane coat
2.12	1.21e-02	GO:0048475	coated membrane
2.63	1.31e-02	GO:0042641	actomyosin
1.62	1.33e-02	GO:0005911	cell-cell junction
2.65	2.04e-02	GO:0000932	cytoplasmic mRNA processing body
1.32	2.57e-02	GO:0015630	microtubule cytoskeleton
1.25	2.72e-02	GO:0044430	cytoskeletal part
1.85	2.89e-02	GO:0019717	synaptosome
1.54	3.31e-02	GO:0016323	basolateral plasma membrane
1.44	3.64e-02	GO:0005815	microtubule organizing center
1.58	4.70e-02	GO:0030425	dendrite

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.22	5.94e-28	GO:0005515	protein binding
1.12	3.75e-25	GO:0005488	binding
1.39	8.35e-07	GO:0030528	transcription regulator activity
1.25	1.09e-06	GO:0000166	nucleotide binding
1.68	2.24e-05	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.54	4.24e-05	GO:0019904	protein domain specific binding
1.41	4.26e-05	GO:0019899	enzyme binding
1.70	5.04e-05	GO:0016881	acid-amino acid ligase activity
1.17	1.31e-04	GO:0003676	nucleic acid binding
1.70	2.72e-04	GO:0019787	small conjugating protein ligase activity
1.57	7.34e-04	GO:0016563	transcription activator activity
1.22	8.26e-04	GO:0017076	purine nucleotide binding
1.22	1.02e-03	GO:0032553	ribonucleotide binding
1.22	1.02e-03	GO:0032555	purine ribonucleotide binding
1.21	1.51e-03	GO:0008270	zinc ion binding
1.57	1.91e-03	GO:0008134	transcription factor binding
1.14	2.00e-03	GO:0046872	metal ion binding
1.22	2.07e-03	GO:0035639	purine ribonucleoside triphosphate binding
1.45	3.07e-03	GO:0016874	ligase activity
1.13	4.59e-03	GO:0043169	cation binding
1.13	5.60e-03	GO:0043167	ion binding
2.47	6.77e-03	GO:0046332	SMAD binding
1.63	7.01e-03	GO:0004842	ubiquitin-protein ligase activity
1.39	7.44e-03	GO:0008092	cytoskeletal protein binding
1.18	9.89e-03	GO:0003677	DNA binding
1.41	1.20e-02	GO:0060589	nucleoside-triphosphatase regulator activity
1.41	1.22e-02	GO:0030695	GTPase regulator activity
1.17	1.48e-02	GO:0046914	transition metal ion binding
1.70	1.81e-02	GO:0004721	phosphoprotein phosphatase activity
1.27	2.00e-02	GO:0001071	nucleic acid binding transcription factor activity
1.27	2.00e-02	GO:0003700	sequence-specific DNA binding transcription factor activity
1.55	2.06e-02	GO:0003702	RNA polymerase II transcription factor activity
1.33	2.33e-02	GO:0043565	sequence-specific DNA binding
3.95	2.79e-02	GO:0070411	I-SMAD binding
1.29	3.06e-02	GO:0003723	RNA binding
2.10	4.66e-02	GO:0019902	phosphatase binding
1.59	4.96e-02	GO:0010843	promoter binding