Motif ID: FOXD3.p2

Z-value: 1.165


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
FOXD3chr1_+_635616320.097.5e-01Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_124135574 2.035 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr2_+_37282516 1.950 LOC100505876
hypothetical LOC100505876
chr7_-_122126422 1.722 NM_139175
RNF133
ring finger protein 133
chr22_+_40372957 1.714 XRCC6
X-ray repair complementing defective repair in Chinese hamster cells 6
chr9_+_101717278 1.571 STX17
syntaxin 17
chr13_+_51496679 1.424 NM_021645
ALG11
UTP14C
asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast)
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr2_-_46988449 1.367 MCFD2
multiple coagulation factor deficiency 2
chr12_+_111375382 1.276 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr5_+_159368721 1.257 TTC1
tetratricopeptide repeat domain 1
chr5_+_159368690 1.214 TTC1
tetratricopeptide repeat domain 1
chr2_-_215998181 1.203 FN1
fibronectin 1
chr4_+_154397975 1.104 TRIM2
tripartite motif containing 2
chr19_+_42409205 1.103 NM_152604
ZNF383
zinc finger protein 383
chr8_+_144802972 1.055 NM_014789
ZNF623
zinc finger protein 623
chr2_-_20390601 1.044 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr14_-_79748273 1.038 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr12_+_27066768 1.038 MED21
mediator complex subunit 21
chr3_+_138159396 1.018 NM_144717
IL20RB
interleukin 20 receptor beta
chr13_-_40491491 0.987 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr9_+_5646582 0.978 NM_020829
KIAA1432
KIAA1432
chr19_+_49221333 0.971 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr3_-_52269467 0.950 WDR82
WD repeat domain 82
chr13_-_40491405 0.905 ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_-_115825742 0.886 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr19_-_23248804 0.884 LOC100132815
hypothetical LOC100132815
chr6_+_74228331 0.881 MTO1
mitochondrial translation optimization 1 homolog (S. cerevisiae)
chr22_-_41366550 0.878 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr12_+_27066749 0.865 NM_004264
MED21
mediator complex subunit 21
chr5_+_159368733 0.861 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr5_+_161427225 0.840 NM_000816
NM_198903
NM_198904
GABRG2


gamma-aminobutyric acid (GABA) A receptor, gamma 2


chr14_-_79747592 0.840 NM_001007023
DIO2
deiodinase, iodothyronine, type II
chr2_+_108751033 0.836 RANBP2
RAN binding protein 2
chr1_-_229071957 0.811 NM_001136494
C1orf198
chromosome 1 open reading frame 198
chr13_-_85271329 0.799 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr19_+_57564981 0.786 NM_001145434
ZNF880
zinc finger protein 880
chr2_+_114390975 0.782 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr9_+_21430439 0.782 NM_024013
IFNA1
interferon, alpha 1
chr20_+_19818209 0.778 NM_018993
RIN2
Ras and Rab interactor 2
chr15_-_70288071 0.769 PKM2
pyruvate kinase, muscle
chr19_+_46762872 0.758 CEACAM21
carcinoembryonic antigen-related cell adhesion molecule 21
chr17_-_8364942 0.755 MYH10
myosin, heavy chain 10, non-muscle
chr15_-_53587723 0.742 NM_001033559
NM_001033560
NM_130810
DYX1C1


dyslexia susceptibility 1 candidate 1


chr6_+_74228174 0.738 NM_001123226
NM_012123
NM_133645
MTO1


mitochondrial translation optimization 1 homolog (S. cerevisiae)


chr21_-_26345294 0.736


chr10_+_124141808 0.729 NM_021622
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr16_+_46835678 0.727 NM_031490
LONP2
lon peptidase 2, peroxisomal
chr5_-_41249270 0.711 NM_000065
C6
complement component 6
chr19_-_14853166 0.708 NM_030901
OR7A17
olfactory receptor, family 7, subfamily A, member 17
chr9_-_106329310 0.708 NM_001001919
OR13C4
olfactory receptor, family 13, subfamily C, member 4
chr15_+_92642433 0.705 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr2_+_241193492 0.703 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr9_-_21325239 0.697 NM_018847
KLHL9
kelch-like 9 (Drosophila)
chr16_+_46835713 0.682 LONP2
lon peptidase 2, peroxisomal
chr6_-_123999640 0.677 NM_006073
TRDN
triadin
chr6_+_114285209 0.672 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr9_+_78305368 0.667 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr8_-_13018123 0.666 NM_001164271
DLC1
deleted in liver cancer 1
chr11_+_101488380 0.665 NM_001195045
YAP1
Yes-associated protein 1
chr11_-_17147863 0.656 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr16_-_219339 0.653 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr9_+_104797413 0.647 NM_001340
CYLC2
cylicin, basic protein of sperm head cytoskeleton 2
chr18_+_59405513 0.645 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr13_-_98708549 0.628 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chrX_-_23955223 0.625 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr20_+_71230 0.624 NM_030931
DEFB126
defensin, beta 126
chr3_-_25658829 0.622 TOP2B
topoisomerase (DNA) II beta 180kDa
chr4_+_146250978 0.622 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr15_-_68781662 0.610 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr13_+_20081940 0.609


chr5_+_140227951 0.601 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr10_-_921694 0.597 NM_015155
LARP4B
La ribonucleoprotein domain family, member 4B
chr9_-_74757735 0.597 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr5_+_139856688 0.593 ANKHD1
ankyrin repeat and KH domain containing 1
chr16_+_2749934 0.591


chr1_-_77457664 0.591 NM_005482
PIGK
phosphatidylinositol glycan anchor biosynthesis, class K
chr4_-_56153135 0.587 NM_152401
PDCL2
phosducin-like 2
chr12_+_20854904 0.587 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_-_59369501 0.586 NM_005142
GIF
gastric intrinsic factor (vitamin B synthesis)
chr2_-_238804953 0.585 LOC151174
hypothetical LOC151174
chr9_-_93917458 0.579 NM_006415
NM_178324
SPTLC1

serine palmitoyltransferase, long chain base subunit 1

chrX_-_76700873 0.579 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr15_+_94677572 0.578 NM_001145157
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_127817143 0.577 NM_006609
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr10_+_118177371 0.576 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr2_-_210726539 0.574 C2orf67
chromosome 2 open reading frame 67
chr12_+_53178834 0.568 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr1_-_168310232 0.564 NM_014970
KIFAP3
kinesin-associated protein 3
chr18_+_64616296 0.562 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr5_-_24680841 0.560 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr4_-_70861301 0.559 NM_001891
CSN2
casein beta
chr1_-_154532019 0.559 NM_144580
C1orf85
chromosome 1 open reading frame 85
chr1_-_154536051 0.558 NM_001004319
VHLL
von Hippel-Lindau tumor suppressor-like
chr3_-_184756101 0.552 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr12_-_44644216 0.551


chr7_+_6583560 0.546 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4



chr3_-_131948202 0.541 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr2_-_218739891 0.540 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr12_+_26017954 0.535 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr1_-_21288259 0.534 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr1_+_70459686 0.533 SRSF11
serine/arginine-rich splicing factor 11
chr19_-_12028126 0.529 NM_001080404
ZNF878
zinc finger protein 878
chr3_-_191650291 0.527 NM_207316
TMEM207
transmembrane protein 207
chr3_+_190990142 0.525 NM_001114980
NM_001114981
NM_001114982
TP63


tumor protein p63


chr20_+_35583020 0.524 NM_005386
NM_181689
NNAT

neuronatin

chr12_+_9871343 0.523 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr4_-_77081118 0.523 NM_001042402
NM_014435
NAAA

N-acylethanolamine acid amidase

chr1_-_154532081 0.521 C1orf85
chromosome 1 open reading frame 85
chr4_+_71096830 0.520 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr5_-_22889487 0.514 NM_004061
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr11_-_102250876 0.514 NM_002426
MMP12
matrix metallopeptidase 12 (macrophage elastase)
chr13_+_77213295 0.513 NM_144595
SLAIN1
SLAIN motif family, member 1
chr4_+_119174211 0.513 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_-_219906142 0.511 NM_001007089
RESP18
regulated endocrine-specific protein 18 homolog (rat)
chr5_-_114543632 0.510 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr13_+_51933228 0.503 CKAP2
cytoskeleton associated protein 2
chr11_-_104332631 0.502 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr12_-_21649019 0.501 NM_021957
GYS2
glycogen synthase 2 (liver)
chr5_-_114660139 0.497 NM_001040440
CCDC112
coiled-coil domain containing 112
chr16_+_27248806 0.497 IL4R
interleukin 4 receptor
chr5_+_159546951 0.493 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr14_+_66901237 0.493 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr22_-_45037882 0.490 NM_006071
PKDREJ
polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)
chr21_-_30791298 0.488 NM_181610
KRTAP19-4
keratin associated protein 19-4
chr17_-_16038607 0.487 NM_001190438
NM_001190440
NCOR1

nuclear receptor corepressor 1

chr8_+_75899326 0.485 NM_015886
PI15
peptidase inhibitor 15
chr18_-_59462469 0.484 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr16_+_24648446 0.482 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr12_-_43731148 0.479 NM_001004329
DBX2
developing brain homeobox 2
chr2_+_115538716 0.476 NM_001178037
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr15_+_22781292 0.476 PAR5
Prader-Willi/Angelman syndrome-5
chr2_+_215885053 0.475 ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr3_+_173954940 0.471 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr3_+_130451160 0.465 COPG
coatomer protein complex, subunit gamma
chr2_+_200879040 0.465 NM_001100422
NM_001100424
NM_001100423
SPATS2L


spermatogenesis associated, serine-rich 2-like


chr17_+_63144500 0.463 NM_015462
NOL11
nucleolar protein 11
chr3_-_150569574 0.463 TM4SF1
transmembrane 4 L six family member 1
chr3_-_193928038 0.460 NM_004113
FGF12
fibroblast growth factor 12
chr14_-_19553191 0.457 NM_001004712
OR4K14
olfactory receptor, family 4, subfamily K, member 14
chr16_+_68238460 0.455 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr16_+_20328355 0.454 NM_017888
ACSM5
acyl-CoA synthetase medium-chain family member 5
chr20_+_18070867 0.454 NM_020536
CSRP2BP
CSRP2 binding protein
chr12_+_73219826 0.454


chr20_+_47986309 0.452 NM_018683
RNF114
ring finger protein 114
chr4_+_106693225 0.450 NM_017700
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr19_-_62348381 0.450 NM_052882
ZIM3
zinc finger, imprinted 3
chr2_+_191222077 0.448 NM_005966
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr21_-_30786145 0.446 NM_181609
KRTAP19-3
keratin associated protein 19-3
chr4_+_38722593 0.445 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr4_+_71126376 0.444 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr5_+_92944680 0.444 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_-_10215942 0.442 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr6_+_109557199 0.438 NM_173830
CEP57L1
centrosomal protein 57kDa-like 1
chr1_+_190811479 0.438 NM_002922
RGS1
regulator of G-protein signaling 1
chr8_-_101384633 0.437 NM_015435
RNF19A
ring finger protein 19A
chr3_+_87359088 0.436 NM_014043
CHMP2B
chromatin modifying protein 2B
chr9_-_88751923 0.436 NM_002048
GAS1
growth arrest-specific 1
chr16_+_8622974 0.431 NM_024109
METTL22
methyltransferase like 22
chr14_-_101617680 0.429 HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr6_-_117853710 0.427 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr6_-_87861492 0.420 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr11_-_77730573 0.419 NM_012296
GAB2
GRB2-associated binding protein 2
chr14_-_19252330 0.419 NM_001197287
OR11H2
olfactory receptor, family 11, subfamily H, member 2
chr6_+_45404031 0.418 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr17_-_60439764 0.416 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr1_+_205344200 0.416 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr14_+_55148488 0.416 KTN1
kinectin 1 (kinesin receptor)
chr3_+_123779122 0.415 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chr8_+_104452877 0.415 CTHRC1
collagen triple helix repeat containing 1
chr13_+_75092570 0.414 NM_005358
LMO7
LIM domain 7
chr11_-_83661878 0.414 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr11_-_55438633 0.406 NM_001001960
OR5W2
olfactory receptor, family 5, subfamily W, member 2
chrX_-_32340291 0.401 NM_004011
NM_004012
DMD

dystrophin

chr12_-_122400937 0.401 NM_001167856
NM_018183
SBNO1

strawberry notch homolog 1 (Drosophila)

chr1_+_107485071 0.400 NTNG1
netrin G1
chr5_+_162865128 0.400 NM_013283
MAT2B
methionine adenosyltransferase II, beta
chr7_+_111908143 0.399 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr19_-_44014228 0.398 NM_001398
ECH1
enoyl CoA hydratase 1, peroxisomal
chr12_-_10983072 0.397 NM_023922
TAS2R14
taste receptor, type 2, member 14
chr11_+_48194937 0.396 NM_001005470
OR4B1
olfactory receptor, family 4, subfamily B, member 1
chr10_-_98315090 0.395 TM9SF3
transmembrane 9 superfamily member 3
chr17_-_30909219 0.395 NM_001129820
SLFN14
schlafen family member 14
chr18_+_59521173 0.395 NM_080475
SERPINB11
serpin peptidase inhibitor, clade B (ovalbumin), member 11 (gene/pseudogene)
chr7_+_90176647 0.395 NM_012395
CDK14
cyclin-dependent kinase 14
chr1_-_151352587 0.394 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr10_+_5228756 0.394 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr10_-_31328426 0.393 NM_001143769
ZNF438
zinc finger protein 438
chr12_-_44919818 0.393 SLC38A1
solute carrier family 38, member 1
chr12_+_9925354 0.390 NM_001190765
KLRF2
killer cell lectin-like receptor subfamily F, member 2
chr11_+_61943082 0.389 NM_003357
SCGB1A1
secretoglobin, family 1A, member 1 (uteroglobin)
chr19_+_14460757 0.387 NM_001146693
LOC100130932
small nuclear ribonucleoprotein G-like protein
chr20_+_47986342 0.387 RNF114
ring finger protein 114
chr1_+_84402962 0.386 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr20_+_47986335 0.383 RNF114
ring finger protein 114
chr3_+_130451119 0.383 NM_016128
COPG
coatomer protein complex, subunit gamma
chr7_+_120490054 0.382 C7orf58
chromosome 7 open reading frame 58
chr2_+_143351695 0.381 KYNU
kynureninase
chr4_-_153523113 0.381 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr20_+_5935897 0.378 NM_001127458
CRLS1
cardiolipin synthase 1
chr20_+_11846536 0.378 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr8_+_17874128 0.378 PCM1
pericentriolar material 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.95 1.40e-10 GO:0007608 sensory perception of smell
1.89 1.79e-10 GO:0007606 sensory perception of chemical stimulus
1.41 3.23e-03 GO:0007600 sensory perception
4.34 1.09e-02 GO:0015721 bile acid and bile salt transport

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.14 6.04e-03 GO:0005886 plasma membrane
1.13 1.50e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.98 3.30e-11 GO:0004984 olfactory receptor activity
1.46 3.21e-05 GO:0004930 G-protein coupled receptor activity
1.33 3.43e-04 GO:0004888 transmembrane receptor activity
1.26 3.35e-03 GO:0004872 receptor activity