Motif ID: POU2F1..3.p2

Z-value: 2.046


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F1chr1_+_1654565720.486.0e-02Click!
POU2F2chr19_-_473283990.476.5e-02Click!
POU2F3chr11_+_1196161120.263.4e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_21407066 6.546


chr22_+_21370394 6.525 IGL@
immunoglobulin lambda locus
chr22_+_21495273 6.045


chr6_+_26232351 5.978 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr6_-_26232109 5.920 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr22_+_21340757 5.693


chr6_+_27969181 5.185 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr6_-_27968906 4.690 NM_003514
HIST1H2AM
histone cluster 1, H2am
chr22_+_20715340 4.522


chr22_+_21384862 4.423 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr22_+_20880159 3.920 IGLV6-57
immunoglobulin lambda variable 6-57
chr22_+_20316968 3.825 NM_152612
CCDC116
coiled-coil domain containing 116
chr22_+_21094094 3.753


chr22_+_20899155 3.732


chr22_+_21116283 3.503


chr22_+_20880112 3.500


chr22_+_21042091 3.485 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr16_+_23754822 3.347 PRKCB
protein kinase C, beta
chr16_+_23754860 3.262 PRKCB
protein kinase C, beta
chr16_+_23754772 3.136 NM_002738
NM_212535
PRKCB

protein kinase C, beta


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
enrichment   p-value GO term description
10.77 2.46e-16 GO:0006334 nucleosome assembly
10.22 9.94e-16 GO:0031497 chromatin assembly
10.11 2.61e-16 GO:0034728 nucleosome organization
9.36 9.94e-15 GO:0065004 protein-DNA complex assembly
9.22 3.24e-15 GO:0071824 protein-DNA complex subunit organization
7.90 4.91e-14 GO:0006333 chromatin assembly or disassembly
7.83 9.36e-13 GO:0006323 DNA packaging
6.99 4.27e-12 GO:0071103 DNA conformation change
3.41 9.02e-06 GO:0034622 cellular macromolecular complex assembly
3.24 9.02e-07 GO:0006325 chromatin organization
2.92 3.69e-05 GO:0034621 cellular macromolecular complex subunit organization
2.56 2.29e-04 GO:0051276 chromosome organization
2.39 4.43e-02 GO:0009628 response to abiotic stimulus
2.33 1.67e-03 GO:0065003 macromolecular complex assembly
2.21 3.96e-03 GO:0006955 immune response
2.11 9.43e-03 GO:0006952 defense response
2.06 1.64e-02 GO:0043933 macromolecular complex subunit organization
2.06 4.43e-02 GO:0071844 cellular component assembly at cellular level
1.82 2.25e-02 GO:0002376 immune system process
1.70 2.01e-02 GO:0006996 organelle organization

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
15.51 1.01e-20 GO:0000786 nucleosome
9.91 1.64e-15 GO:0032993 protein-DNA complex
5.68 6.90e-14 GO:0000785 chromatin
3.26 6.55e-08 GO:0044427 chromosomal part
3.04 5.30e-08 GO:0005694 chromosome
1.52 9.47e-04 GO:0043228 non-membrane-bounded organelle
1.52 9.47e-04 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
12.02 3.55e-08 GO:0003823 antigen binding
1.58 1.29e-03 GO:0003677 DNA binding