Motif ID: MAZ.p2

Z-value: 3.859


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297261950.611.2e-02Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_809879 12.300 NM_006651
CPLX1
complexin 1
chr2_+_232281470 7.114 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr20_-_61574259 6.605 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr2_+_232281491 6.579 PTMA
prothymosin, alpha
chr1_-_1465602 6.184 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr4_+_995609 5.855 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr4_+_995395 5.589 FGFRL1
fibroblast growth factor receptor-like 1
chr19_+_1200882 5.143 MIDN
midnolin
chr19_+_540849 5.134 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr10_-_103525646 4.740 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr7_+_5289079 4.686 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr19_+_748390 4.200 NM_002819
NM_031990
NM_031991
NM_175847
PTBP1



polypyrimidine tract binding protein 1



chr11_+_56984702 4.181 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr6_+_37245860 4.084 NM_002648
PIM1
pim-1 oncogene
chr6_+_33046706 4.024 BRD2
bromodomain containing 2
chr21_+_46226072 4.019 NM_001848
COL6A1
collagen, type VI, alpha 1
chr11_+_359723 4.011 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr19_+_54786723 4.008 NM_020719
PRR12
proline rich 12
chr17_-_1029758 3.986 NM_021962
ABR
active BCR-related gene
chr17_+_7682355 3.834



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 123 entries
enrichment   p-value GO term description
2.27 9.94e-03 GO:0051412 response to corticosterone stimulus
1.88 3.69e-02 GO:0001708 cell fate specification
1.85 1.04e-02 GO:0048663 neuron fate commitment
1.75 1.15e-03 GO:0009953 dorsal/ventral pattern formation
1.70 3.41e-03 GO:0022612 gland morphogenesis
1.58 2.17e-05 GO:0045165 cell fate commitment
1.47 3.70e-06 GO:0045596 negative regulation of cell differentiation
1.45 1.17e-03 GO:0048732 gland development
1.44 1.29e-03 GO:0001701 in utero embryonic development
1.44 1.83e-03 GO:0045664 regulation of neuron differentiation
1.43 4.45e-02 GO:0048562 embryonic organ morphogenesis
1.39 3.97e-03 GO:0048568 embryonic organ development
1.39 7.91e-03 GO:0002009 morphogenesis of an epithelium
1.39 4.56e-02 GO:0032582 negative regulation of gene-specific transcription
1.38 3.90e-03 GO:0050767 regulation of neurogenesis
1.37 1.70e-11 GO:0030182 neuron differentiation
1.37 1.93e-05 GO:0009792 embryo development ending in birth or egg hatching
1.37 3.74e-05 GO:0043009 chordate embryonic development
1.37 2.23e-04 GO:0051093 negative regulation of developmental process
1.37 4.36e-04 GO:0060284 regulation of cell development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.54 4.60e-02 GO:0033267 axon part
1.46 1.61e-04 GO:0030424 axon
1.38 7.79e-04 GO:0016323 basolateral plasma membrane
1.32 1.02e-04 GO:0043005 neuron projection
1.28 1.74e-03 GO:0045202 synapse
1.20 2.91e-02 GO:0030054 cell junction
1.16 6.71e-07 GO:0005829 cytosol
1.14 3.76e-06 GO:0043233 organelle lumen
1.14 7.21e-06 GO:0070013 intracellular organelle lumen
1.14 2.31e-05 GO:0044428 nuclear part
1.14 2.52e-04 GO:0031981 nuclear lumen
1.13 1.64e-05 GO:0031974 membrane-enclosed lumen
1.13 8.10e-03 GO:0012505 endomembrane system
1.13 2.51e-02 GO:0005654 nucleoplasm
1.12 5.45e-15 GO:0005634 nucleus
1.09 5.97e-18 GO:0043227 membrane-bounded organelle
1.09 1.15e-17 GO:0043231 intracellular membrane-bounded organelle
1.09 1.65e-16 GO:0005737 cytoplasm
1.09 8.24e-09 GO:0044444 cytoplasmic part
1.08 2.27e-24 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
1.44 2.53e-04 GO:0010843 promoter binding
1.43 2.65e-04 GO:0000975 regulatory region DNA binding
1.43 2.65e-04 GO:0001067 regulatory region nucleic acid binding
1.43 2.65e-04 GO:0044212 transcription regulatory region DNA binding
1.40 5.38e-15 GO:0043565 sequence-specific DNA binding
1.35 2.16e-04 GO:0016563 transcription activator activity
1.33 2.31e-15 GO:0001071 nucleic acid binding transcription factor activity
1.33 2.31e-15 GO:0003700 sequence-specific DNA binding transcription factor activity
1.26 8.53e-09 GO:0030528 transcription regulator activity
1.18 3.82e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.17 7.99e-10 GO:0003677 DNA binding
1.11 7.09e-19 GO:0005515 protein binding
1.11 6.73e-06 GO:0003676 nucleic acid binding
1.11 1.14e-02 GO:0000166 nucleotide binding
1.06 1.15e-15 GO:0005488 binding