Motif ID: HMX1.p2

Z-value: 1.770


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
HMX1 3166 H6 family homeobox 1



Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_-_21442663 2.453 NM_002509
 NKX2-2
NK2 homeobox 2
chr8_+_32525269 2.415 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
 NRG1










neuregulin 1










chr10_-_99521701 2.318 NM_003015
 SFRP5
secreted frizzled-related protein 5
chr3_+_57969127 2.061 NM_001164317
NM_001164318
NM_001164319
NM_001457
 FLNB



filamin B, beta



chr10_+_94811010 2.026 NM_183374
 CYP26C1
cytochrome P450, family 26, subfamily C, polypeptide 1
chrX_+_48915127 1.946 NM_002668
 PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr11_+_268569 1.830 NM_138329
 NLRP6
NLR family, pyrin domain containing 6
chr19_+_590878 1.771 NM_020637
 FGF22
fibroblast growth factor 22
chr19_+_43447078 1.641 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr15_-_75694674 1.597 LINGO1
leucine rich repeat and Ig domain containing 1
chr12_+_4253143 1.587 NM_001759
 CCND2
cyclin D2
chr10_+_103882776 1.585 NM_015062
 PPRC1
peroxisome proliferator-activated receptor gamma, coactivator-related 1
chr7_+_5609416 1.544 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_+_43446937 1.477 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr19_+_43447262 1.433 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr20_+_2581177 1.377 NM_006392
 NOP56
NOP56 ribonucleoprotein homolog (yeast)
chr22_-_35011703 1.363 MYH9
myosin, heavy chain 9, non-muscle
chr5_+_148186348 1.358 NM_000024
 ADRB2
adrenergic, beta-2-, receptor, surface
chr20_-_538909 1.243 NM_004609
 TCF15
transcription factor 15 (basic helix-loop-helix)
chr1_+_151917674 1.225 NM_000906
 NPR1
natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 42 entries
enrichment   p-value GO term description
2.96 1.11e-02 GO:0050770 regulation of axonogenesis
2.39 1.02e-02 GO:0042692 muscle cell differentiation
2.39 1.48e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.37 1.77e-02 GO:0022604 regulation of cell morphogenesis
2.30 2.30e-04 GO:0045664 regulation of neuron differentiation
2.15 3.12e-04 GO:0050767 regulation of neurogenesis
2.06 4.62e-04 GO:0051960 regulation of nervous system development
2.05 9.93e-05 GO:0060284 regulation of cell development
1.89 2.91e-03 GO:0045597 positive regulation of cell differentiation
1.85 1.81e-04 GO:0051094 positive regulation of developmental process
1.84 2.36e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.81 2.56e-02 GO:0051093 negative regulation of developmental process
1.78 2.53e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.75 4.96e-03 GO:0048812 neuron projection morphogenesis
1.74 1.07e-02 GO:0007409 axonogenesis
1.73 2.11e-03 GO:0031175 neuron projection development
1.72 3.32e-03 GO:0000904 cell morphogenesis involved in differentiation
1.71 5.38e-05 GO:0045595 regulation of cell differentiation
1.66 9.96e-06 GO:0048699 generation of neurons
1.66 7.78e-05 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.33 5.94e-05 GO:0044459 plasma membrane part
1.19 3.28e-03 GO:0005886 plasma membrane
1.18 4.41e-03 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
2.40 3.98e-02 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity