Motif ID: MZF1.p2

Z-value: 2.866


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_63776442-0.263.2e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_138060 5.504 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr8_+_30361485 4.854 NM_001008710
NM_001008711
NM_001008712
NM_006867
 RBPMS



RNA binding protein with multiple splicing



chr20_+_17498507 4.480 NM_001011546
NM_006870
 DSTN

destrin (actin depolymerizing factor)

chr12_+_55808696 4.466 LRP1
low density lipoprotein receptor-related protein 1
chr16_-_3225360 4.363 NM_001145448
NM_198088
NM_001145446
NM_198087
 ZNF200



zinc finger protein 200



chr6_+_7052985 4.174 NM_001003698
NM_001003699
NM_001003700
 RREB1


ras responsive element binding protein 1


chr14_+_31615959 3.686 ARHGAP5
Rho GTPase activating protein 5
chr2_+_54536780 3.677 NM_003128
 SPTBN1
spectrin, beta, non-erythrocytic 1
chr3_+_23219707 3.484 NM_152653
 UBE2E2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr6_+_7053183 3.453 RREB1
ras responsive element binding protein 1
chr10_+_114699953 3.430 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
 TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr2_+_115635982 3.399 NM_001178034
NM_001004360
 DPP10

dipeptidyl-peptidase 10 (non-functional)

chr2_+_54537842 3.364 SPTBN1
spectrin, beta, non-erythrocytic 1
chr12_+_55808514 3.341 NM_002332
 LRP1
low density lipoprotein receptor-related protein 1
chr14_+_59786047 3.326 PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr6_+_149680747 3.303 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr6_+_163755788 3.207 QKI
quaking homolog, KH domain RNA binding (mouse)
chr2_+_182464713 3.157 NM_001130445
NM_006751
 SSFA2

sperm specific antigen 2

chr6_+_7052798 3.103 NM_001168344
 RREB1
ras responsive element binding protein 1
chr9_+_33807168 3.076 NM_017811
 UBE2R2
ubiquitin-conjugating enzyme E2R 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 167 entries
enrichment   p-value GO term description
2.05 1.42e-03 GO:0001933 negative regulation of protein phosphorylation
1.96 1.05e-04 GO:0010563 negative regulation of phosphorus metabolic process
1.96 1.05e-04 GO:0045936 negative regulation of phosphate metabolic process
1.90 1.55e-03 GO:0042326 negative regulation of phosphorylation
1.82 3.74e-02 GO:0051494 negative regulation of cytoskeleton organization
1.72 3.61e-02 GO:0030178 negative regulation of Wnt receptor signaling pathway
1.69 4.32e-09 GO:0051129 negative regulation of cellular component organization
1.67 1.25e-03 GO:0010639 negative regulation of organelle organization
1.59 3.97e-05 GO:0044087 regulation of cellular component biogenesis
1.57 3.20e-03 GO:0031400 negative regulation of protein modification process
1.49 3.91e-04 GO:0030334 regulation of cell migration
1.49 8.49e-04 GO:0032269 negative regulation of cellular protein metabolic process
1.49 2.28e-02 GO:0016569 covalent chromatin modification
1.49 4.96e-02 GO:0051493 regulation of cytoskeleton organization
1.48 1.71e-06 GO:0016568 chromatin modification
1.48 3.84e-02 GO:0016570 histone modification
1.47 9.42e-04 GO:2000145 regulation of cell motility
1.47 9.84e-04 GO:0051248 negative regulation of protein metabolic process
1.46 3.70e-04 GO:0040012 regulation of locomotion
1.46 4.90e-04 GO:0051270 regulation of cellular component movement

Gene overrepresentation in compartment category:

Showing 1 to 20 of 45 entries
enrichment   p-value GO term description
2.31 6.46e-03 GO:0043195 terminal button
2.21 5.62e-05 GO:0008287 protein serine/threonine phosphatase complex
2.16 1.44e-04 GO:0044306 neuron projection terminus
2.14 4.58e-02 GO:0005881 cytoplasmic microtubule
2.12 6.73e-04 GO:0043679 axon terminus
1.79 3.73e-02 GO:0034708 methyltransferase complex
1.79 3.73e-02 GO:0035097 histone methyltransferase complex
1.73 2.38e-02 GO:0030427 site of polarized growth
1.65 1.36e-03 GO:0030055 cell-substrate junction
1.65 3.33e-03 GO:0005925 focal adhesion
1.65 4.12e-02 GO:0033267 axon part
1.63 4.15e-03 GO:0005924 cell-substrate adherens junction
1.61 3.40e-02 GO:0042470 melanosome
1.61 3.40e-02 GO:0048770 pigment granule
1.55 1.42e-04 GO:0030424 axon
1.51 6.65e-03 GO:0005912 adherens junction
1.47 3.02e-03 GO:0030425 dendrite
1.47 8.23e-03 GO:0043025 neuronal cell body
1.47 4.92e-02 GO:0000151 ubiquitin ligase complex
1.45 1.71e-02 GO:0044297 cell body

Gene overrepresentation in function category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
1.97 1.35e-02 GO:0019888 protein phosphatase regulator activity
1.87 2.45e-02 GO:0019208 phosphatase regulator activity
1.54 1.64e-04 GO:0010843 promoter binding
1.52 2.29e-04 GO:0000975 regulatory region DNA binding
1.52 2.29e-04 GO:0001067 regulatory region nucleic acid binding
1.52 2.29e-04 GO:0044212 transcription regulatory region DNA binding
1.47 6.57e-03 GO:0003682 chromatin binding
1.42 5.86e-04 GO:0008134 transcription factor binding
1.38 2.62e-03 GO:0016563 transcription activator activity
1.34 6.10e-04 GO:0019904 protein domain specific binding
1.34 2.26e-02 GO:0016564 transcription repressor activity
1.32 1.64e-06 GO:0019899 enzyme binding
1.32 4.32e-06 GO:0043565 sequence-specific DNA binding
1.27 1.37e-02 GO:0008092 cytoskeletal protein binding
1.26 6.35e-03 GO:0004672 protein kinase activity
1.25 2.57e-05 GO:0030528 transcription regulator activity
1.23 1.25e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.22 1.52e-03 GO:0001071 nucleic acid binding transcription factor activity
1.22 1.52e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.21 3.12e-02 GO:0016301 kinase activity