Motif ID: HSF1,2.p2

Z-value: 1.394


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
HSF1 3297 heat shock transcription factor 1
HSF2 3298 heat shock transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HSF2chr6_+_122762384-0.533.6e-02Click!
HSF1chr8_+_1454860960.097.5e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_-_44723116 2.072 NM_001190823
 SMAD7
SMAD family member 7
chr14_-_21108714 1.651 NM_001005465
 OR10G3
olfactory receptor, family 10, subfamily G, member 3
chr22_-_35011703 1.431 MYH9
myosin, heavy chain 9, non-muscle
chrX_+_115215985 1.338 NM_000686
 AGTR2
angiotensin II receptor, type 2
chr10_+_104525877 1.154 NM_017787
 C10orf26
chromosome 10 open reading frame 26
chr13_-_97916768 1.052 STK24
serine/threonine kinase 24
chr2_+_113973130 1.031 NM_012184
 FOXD4L1
forkhead box D4-like 1
chr18_+_29573152 1.003 ASXL3
additional sex combs like 3 (Drosophila)
chr19_-_47638890 0.986 NM_198477
 CXCL17
chemokine (C-X-C motif) ligand 17
chr9_+_108726257 0.978 ZNF462
zinc finger protein 462
chr17_+_9686572 0.975 GLP2R
glucagon-like peptide 2 receptor
chrX_+_27736027 0.956 NM_182506
 MAGEB10
melanoma antigen family B, 10
chr9_-_72926333 0.949 NM_001007471
 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr3_+_191588354 0.943 NM_006580
 CLDN16
claudin 16
chr2_-_240613480 0.914 NM_004544
 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr11_-_404975 0.908 NM_001135054
 SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr5_+_147423727 0.908 NM_001127698
NM_001127699
NM_006846
 SPINK5


serine peptidase inhibitor, Kazal type 5


chr2_-_100125402 0.889 NM_002285
 AFF3
AF4/FMR2 family, member 3
chr2_-_210876560 0.878 NM_079422
 MYL1
myosin, light chain 1, alkali; skeletal, fast
chr16_-_2254318 0.850 RNPS1
RNA binding protein S1, serine-rich domain

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 23 entries
enrichment   p-value GO term description
6.51 3.12e-02 GO:0048880 sensory system development
6.51 3.12e-02 GO:0048892 lateral line nerve development
6.51 3.12e-02 GO:0048895 lateral line nerve glial cell differentiation
6.51 3.12e-02 GO:0048925 lateral line system development
6.51 3.12e-02 GO:0048937 lateral line nerve glial cell development
6.51 3.12e-02 GO:0050935 iridophore differentiation
5.02 3.89e-02 GO:0048484 enteric nervous system development
2.47 1.13e-02 GO:0048754 branching morphogenesis of a tube
1.72 3.33e-02 GO:0007411 axon guidance
1.56 2.17e-02 GO:0006928 cellular component movement
1.56 4.97e-02 GO:0006935 chemotaxis
1.56 4.97e-02 GO:0042330 taxis
1.50 1.07e-03 GO:0040011 locomotion
1.42 2.35e-02 GO:0048468 cell development
1.33 2.47e-03 GO:0003008 system process
1.30 2.97e-03 GO:0030154 cell differentiation
1.28 5.88e-03 GO:0048869 cellular developmental process
1.26 7.64e-04 GO:0048731 system development
1.25 1.09e-04 GO:0007275 multicellular organismal development
1.24 2.89e-09 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.63 5.70e-03 GO:0005604 basement membrane
2.15 2.03e-02 GO:0044420 extracellular matrix part
1.65 2.82e-02 GO:0005578 proteinaceous extracellular matrix
1.62 1.18e-02 GO:0031012 extracellular matrix
1.49 9.71e-06 GO:0044421 extracellular region part
1.41 1.36e-02 GO:0005615 extracellular space
1.27 1.73e-03 GO:0005576 extracellular region
1.20 4.10e-05 GO:0071944 cell periphery
1.20 7.06e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.99 3.42e-02 GO:0004866 endopeptidase inhibitor activity
1.97 3.50e-02 GO:0061135 endopeptidase regulator activity
1.94 4.68e-02 GO:0030414 peptidase inhibitor activity