Motif ID: SRY.p2

Z-value: 2.001


Transcription factors associated with SRY.p2:

Gene SymbolEntrez IDGene Name
SRY 6736 sex determining region Y



Activity profile for motif SRY.p2.

activity profile for motif SRY.p2


Sorted Z-values histogram for motif SRY.p2

Sorted Z-values for motif SRY.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SRY.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_55053398 2.743


chr2_-_55090759 2.580 NM_007008
RTN4
reticulon 4
chr7_+_113853790 2.415 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr12_+_77963563 2.378 NM_001135806
SYT1
synaptotagmin I
chr14_-_30927931 2.291 NM_015473
HEATR5A
HEAT repeat containing 5A
chr2_-_39310176 2.286 NM_001009565
CDKL4
cyclin-dependent kinase-like 4
chr11_+_101488380 2.228 NM_001195045
YAP1
Yes-associated protein 1
chr8_-_125785611 2.162 MTSS1
metastasis suppressor 1
chr7_-_83108682 2.110 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_36929520 2.094 STRN
striatin, calmodulin binding protein
chr12_+_54132264 2.080 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr3_+_180348818 2.006 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr3_-_192531018 1.858 NM_198152
UTS2D
urotensin 2 domain containing
chr15_-_23201740 1.843 NM_130838
UBE3A
ubiquitin protein ligase E3A
chr20_+_11846536 1.840 NM_014962
BTBD3
BTB (POZ) domain containing 3
chr12_+_26096757 1.835 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr9_+_71009746 1.819 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr13_-_32678142 1.757 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_165768798 1.754 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr5_-_86739683 1.731 CCNH
cyclin H
chr11_+_22652957 1.724 GAS2
growth arrest-specific 2
chr2_-_174475528 1.710


chr2_+_101680594 1.698 NM_004834
NM_145686
NM_145687
MAP4K4


mitogen-activated protein kinase kinase kinase kinase 4


chr15_+_47502666 1.692 NM_002009
FGF7
fibroblast growth factor 7
chr2_-_215967442 1.653 FN1
fibronectin 1
chr9_-_27287106 1.587 NM_001161585
NM_020641
C9orf11

chromosome 9 open reading frame 11

chr11_-_5766621 1.582 NM_001001913
OR52N1
olfactory receptor, family 52, subfamily N, member 1
chr1_-_196776697 1.558 NM_133262
NM_133326
ATP6V1G3

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3

chr3_-_121117647 1.545 GSK3B
glycogen synthase kinase 3 beta
chr1_-_21288259 1.529 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr11_+_22652894 1.526 NM_005256
GAS2
growth arrest-specific 2
chr6_+_64414389 1.497 NM_015153
PHF3
PHD finger protein 3
chr2_+_228386800 1.492 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr11_-_55460451 1.456 NM_006637
OR5I1
olfactory receptor, family 5, subfamily I, member 1
chr5_+_121493113 1.454 NM_207317
ZNF474
zinc finger protein 474
chr17_-_36570508 1.446 NM_032524
KRTAP4-4
keratin associated protein 4-4
chr4_-_101658094 1.435 NM_001159694
NM_016242
EMCN

endomucin

chr3_-_121065112 1.434


chr11_+_129484540 1.430 APLP2
amyloid beta (A4) precursor-like protein 2
chr7_+_116182676 1.422


chr10_+_90414125 1.416 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr11_-_7684516 1.389 NM_198185
OVCH2
ovochymase 2 (gene/pseudogene)
chr10_-_116241572 1.389


chr2_+_196229715 1.365 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr11_+_54891935 1.363 NM_001005275
OR4A15
olfactory receptor, family 4, subfamily A, member 15
chr2_-_215951161 1.348 FN1
fibronectin 1
chr3_-_107070400 1.321 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr7_-_19778928 1.317 NM_152774
TMEM196
transmembrane protein 196
chr20_+_23293020 1.307 NM_022482
GZF1
GDNF-inducible zinc finger protein 1
chr4_-_56153135 1.305 NM_152401
PDCL2
phosducin-like 2
chr5_-_146415782 1.300 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr16_+_55373241 1.285 NUP93
nucleoporin 93kDa
chr13_+_23042722 1.280 NM_148957
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr7_-_26202626 1.274 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_+_190372456 1.265 NM_198485
TPRG1
tumor protein p63 regulated 1
chr8_-_62764839 1.256 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr3_+_23904086 1.248 UBE2E1
ubiquitin-conjugating enzyme E2E 1 (UBC4/5 homolog, yeast)
chr15_-_68781662 1.230 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr17_-_10313600 1.227 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr9_-_103237851 1.221 NM_000035
ALDOB
aldolase B, fructose-bisphosphate
chr7_-_93027057 1.218 NM_001164738
CALCR
calcitonin receptor
chr9_+_80134302 1.215 PSAT1
phosphoserine aminotransferase 1
chr6_-_64087806 1.211 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr3_+_173954940 1.210 NM_018098
ECT2
epithelial cell transforming sequence 2 oncogene
chr11_+_43337042 1.207 TTC17
tetratricopeptide repeat domain 17
chr12_+_32546243 1.199 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_89976261 1.191 NM_007035
KERA
keratocan
chr7_-_18033970 1.189 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr3_+_12367993 1.188 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr7_+_106897737 1.186 NM_005295
GPR22
G protein-coupled receptor 22
chr2_+_120233676 1.182 NM_002830
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr16_+_14187965 1.179 MKL2
MKL/myocardin-like 2
chr5_+_147754467 1.173 FBXO38
F-box protein 38
chr3_+_179736917 1.172 NM_181361
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr17_-_36451189 1.169 NM_030967
KRTAP1-3
KRTAP1-1
keratin associated protein 1-3
keratin associated protein 1-1
chr7_-_86526880 1.165 NM_001142749
KIAA1324L
KIAA1324-like
chr10_-_98280299 1.159 TM9SF3
transmembrane 9 superfamily member 3
chr8_+_21833162 1.157 XPO7
exportin 7
chr2_+_62787534 1.157 NM_001142614
EHBP1
EH domain binding protein 1
chr7_+_134114912 1.139 CALD1
caldesmon 1
chr4_+_42590038 1.138 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr1_-_7998265 1.130 ERRFI1
ERBB receptor feedback inhibitor 1
chr22_-_39189369 1.122 MKL1
megakaryoblastic leukemia (translocation) 1
chr10_+_49184658 1.118 MAPK8
mitogen-activated protein kinase 8
chr4_+_71298187 1.112 NM_021225
PROL1
proline rich, lacrimal 1
chr12_-_11354620 1.111 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr13_+_51933228 1.111 CKAP2
cytoskeleton associated protein 2
chr4_+_75242671 1.093 NM_001144978
MTHFD2L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
chr6_+_130381408 1.088 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr12_+_79362256 1.086 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr5_-_111340421 1.077 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr1_+_25537372 1.073 NM_014313
TMEM50A
transmembrane protein 50A
chr8_+_79740813 1.068 NM_016010
FAM164A
family with sequence similarity 164, member A
chr8_-_40874485 1.067 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr17_+_36642240 1.063 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr2_+_38031099 1.062 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr9_-_21472311 1.062 NM_176891
IFNE
interferon, epsilon
chr18_+_64616296 1.062 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr9_+_74956494 1.061 NM_000700
ANXA1
annexin A1
chr11_-_121492010 1.053 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr6_+_97117144 1.047 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr7_+_134114957 1.042 CALD1
caldesmon 1
chr9_+_74956614 1.040 ANXA1
annexin A1
chr1_+_66230977 1.038 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr3_+_150028130 1.034 NM_001871
CPB1
carboxypeptidase B1 (tissue)
chr12_-_60872814 1.026 NM_178539
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr14_-_24047261 1.025 NM_001836
CMA1
chymase 1, mast cell
chr11_-_27637771 1.019 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr6_-_49820030 1.010 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr8_+_103633023 1.010 NM_024410
ODF1
outer dense fiber of sperm tails 1
chr4_+_146250978 1.008 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr1_-_150564302 1.005 NM_002016
FLG
filaggrin
chr12_-_61283474 1.004 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr9_+_112470871 1.002 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_-_167037861 1.000 BCHE
butyrylcholinesterase
chr2_+_88966170 0.997


chr10_-_61570665 0.992 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_113656762 0.989 NM_024019
NEUROG2
neurogenin 2
chr10_+_63478974 0.986 ARID5B
AT rich interactive domain 5B (MRF1-like)
chr9_+_90193807 0.984 SPIN1
spindlin 1
chr5_+_143171918 0.975 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr9_+_36026900 0.972 NM_021111
RECK
reversion-inducing-cysteine-rich protein with kazal motifs
chr2_-_207738858 0.971 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chr16_+_24475129 0.967 RBBP6
retinoblastoma binding protein 6
chr3_-_115380539 0.959 NM_000796
NM_033663
DRD3

dopamine receptor D3

chr20_-_21326046 0.958 NM_033176
NKX2-4
NK2 homeobox 4
chr4_+_74500748 0.958 ALB
albumin
chr8_-_18710575 0.954 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr16_+_68284252 0.952 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_-_13474101 0.946 NM_000315
PTH
parathyroid hormone
chr2_-_162883062 0.944 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr12_+_70618892 0.942 NM_173353
TPH2
tryptophan hydroxylase 2
chr4_+_110968594 0.942 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr4_+_146623405 0.940 NM_001003688
SMAD1
SMAD family member 1
chr21_+_37377116 0.938 NM_003316
TTC3
tetratricopeptide repeat domain 3
chr7_+_20653490 0.937 NM_001163942
NM_001163993
NM_178559
ABCB5


ATP-binding cassette, sub-family B (MDR/TAP), member 5


chr2_+_166034402 0.935 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr10_-_98263434 0.935 NM_012465
TLL2
tolloid-like 2
chr7_+_129057152 0.934 NM_001040110
NRF1
nuclear respiratory factor 1
chr6_-_119137923 0.923 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr1_+_84402962 0.916 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr2_+_202949289 0.913 NM_001204
BMPR2
bone morphogenetic protein receptor, type II (serine/threonine kinase)
chr11_-_4675524 0.907 NM_030774
OR51E2
olfactory receptor, family 51, subfamily E, member 2
chr5_+_140723939 0.900 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr2_+_190981257 0.899 NM_017694
MFSD6
major facilitator superfamily domain containing 6
chr17_+_36665161 0.893 NM_030975
KRTAP9-9
keratin associated protein 9-9
chr3_-_197726587 0.888 NM_001077657
C3orf43
chromosome 3 open reading frame 43
chr15_-_100280784 0.888 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr12_-_11439752 0.886 NM_006248
PRB1
PRB2
proline-rich protein BstNI subfamily 1
proline-rich protein BstNI subfamily 2
chr18_+_27425727 0.886 NM_000371
TTR
transthyretin
chr21_-_14501114 0.885 NM_198996
LIPI
lipase, member I
chr4_-_153523113 0.882 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr20_+_2892918 0.879 PTPRA
protein tyrosine phosphatase, receptor type, A
chr9_-_41944687 0.878 MGC21881
hypothetical locus MGC21881
chr2_-_162717159 0.878 NM_002054
GCG
glucagon
chr3_-_47909001 0.877 MAP4
microtubule-associated protein 4
chr21_+_24722913 0.875 FLJ42200
FLJ42200 protein
chr6_-_117853710 0.874 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr12_-_11041740 0.873 NM_176889
TAS2R20
taste receptor, type 2, member 20
chr13_+_75232797 0.872 NM_015842
LMO7
LIM domain 7
chr9_-_21375258 0.866 NM_000605
IFNA2
interferon, alpha 2
chr2_+_224530361 0.863 NM_022915
MRPL44
mitochondrial ribosomal protein L44
chr15_-_23204887 0.862 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr5_+_57823017 0.862 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr11_+_36274300 0.860 NM_001160167
PRR5L
proline rich 5 like
chr4_-_104240413 0.859 NM_020139
BDH2
3-hydroxybutyrate dehydrogenase, type 2
chr4_-_64957595 0.859 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr7_+_93373755 0.854 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_-_215998181 0.853 FN1
fibronectin 1
chr3_-_99236520 0.851 NM_001105580
GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chr12_+_9871343 0.850 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr18_+_59733724 0.849 NM_005024
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr4_-_68432293 0.845 NM_004262
TMPRSS11D
transmembrane protease, serine 11D
chr2_-_148495642 0.845 NM_181742
ORC4
origin recognition complex, subunit 4
chr12_-_14858358 0.845 NM_001013698
C12orf69
chromosome 12 open reading frame 69
chr12_+_74014685 0.844 NM_152779
GLIPR1L1
GLI pathogenesis-related 1 like 1
chr9_+_74956601 0.843 ANXA1
annexin A1
chr21_+_30929425 0.842 NM_181616
KRTAP20-2
keratin associated protein 20-2
chr4_-_105635499 0.842 CXXC4
CXXC finger protein 4
chr3_+_70131572 0.835


chr12_-_10846435 0.828 NM_023919
TAS2R7
taste receptor, type 2, member 7
chr1_+_61320213 0.825 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr1_+_61319976 0.821 NM_001145512
NFIA
nuclear factor I/A
chr11_+_5925152 0.821 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr11_+_57285809 0.819 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001331
CTNND1












catenin (cadherin-associated protein), delta 1












chr11_-_51269023 0.819 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr1_+_81544432 0.813 LPHN2
latrophilin 2
chr1_-_177106702 0.811 NM_004673
ANGPTL1
angiopoietin-like 1
chr3_+_44258381 0.810 NM_001145030
C3orf77
chromosome 3 open reading frame 77
chr12_+_26017954 0.808 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr15_+_45797977 0.807 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr2_-_231697999 0.806 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr20_+_9236446 0.805 NM_000933
PLCB4
phospholipase C, beta 4
chr4_-_186537145 0.804 NM_018409
LRP2BP
LRP2 binding protein
chr12_+_15590811 0.799 PTPRO
protein tyrosine phosphatase, receptor type, O
chr3_+_115099007 0.798 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr13_-_25687062 0.790 RNF6
ring finger protein (C3H2C3 type) 6
chr16_-_3783475 0.788 CREBBP
CREB binding protein
chr5_+_162865128 0.786 NM_013283
MAT2B
methionine adenosyltransferase II, beta
chr5_-_22889192 0.781 CDH12
cadherin 12, type 2 (N-cadherin 2)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.19 1.96e-18 GO:0007606 sensory perception of chemical stimulus
2.26 2.07e-18 GO:0007608 sensory perception of smell
1.75 1.29e-13 GO:0007600 sensory perception
1.41 2.07e-06 GO:0050877 neurological system process
1.31 2.24e-04 GO:0003008 system process
1.13 1.21e-02 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.32 1.11e-19 GO:0004984 olfactory receptor activity
1.63 2.48e-10 GO:0004930 G-protein coupled receptor activity
1.43 2.23e-07 GO:0004888 transmembrane receptor activity
1.35 9.62e-07 GO:0004872 receptor activity
1.28 4.19e-05 GO:0004871 signal transducer activity
1.28 4.19e-05 GO:0060089 molecular transducer activity