Motif ID: ATF5_CREB3.p2

Z-value: 2.562


Transcription factors associated with ATF5_CREB3.p2:

Gene SymbolEntrez IDGene Name
ATF5 22809 activating transcription factor 5
CREB3 10488 cAMP responsive element binding protein 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
CREB3chr9_+_357222070.793.0e-04Click!
ATF5chr19_+_55123770-0.322.3e-01Click!


Activity profile for motif ATF5_CREB3.p2.

activity profile for motif ATF5_CREB3.p2


Sorted Z-values histogram for motif ATF5_CREB3.p2

Sorted Z-values for motif ATF5_CREB3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF5_CREB3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_12652427 4.743 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr6_+_64340408 4.326 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_+_64339869 4.233 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr6_+_64340388 4.232 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_-_113933457 4.097 NM_020918
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr2_-_156897286 3.750 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr17_+_64020120 3.134 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr8_+_64243741 3.089 YTHDF3
YTH domain family, member 3
chr17_+_64020155 3.027 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr8_+_64243662 3.000 NM_152758
YTHDF3
YTH domain family, member 3
chr5_+_56505412 2.995 NM_022913
GPBP1
GC-rich promoter binding protein 1
chr12_+_70435176 2.953 RAB21
RAB21, member RAS oncogene family
chr5_+_56505608 2.918 GPBP1
GC-rich promoter binding protein 1
chr17_+_64020159 2.849 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr12_+_22669352 2.847 ETNK1
ethanolamine kinase 1
chr2_+_28469275 2.838 NM_005253
FOSL2
FOS-like antigen 2
chr6_+_89848229 2.798 PNRC1
proline-rich nuclear receptor coactivator 1
chr17_+_8279860 2.737 NM_001025579
NM_030808
NDEL1

nudE nuclear distribution gene E homolog (A. nidulans)-like 1

chr2_+_28469172 2.724 FOSL2
FOS-like antigen 2
chr17_+_55051818 2.719 NM_004859
CLTC
clathrin, heavy chain (Hc)
chr12_+_22669275 2.659 NM_001039481
NM_018638
ETNK1

ethanolamine kinase 1

chr20_+_32610161 2.648 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr20_+_32755778 2.629 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr2_+_206847658 2.559 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr8_+_26296439 2.435 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr16_+_55523248 2.435 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr2_+_105320247 2.425 C2orf49
chromosome 2 open reading frame 49
chr2_+_105320440 2.372 NM_024093
C2orf49
chromosome 2 open reading frame 49
chr12_+_70434927 2.369 RAB21
RAB21, member RAS oncogene family
chr2_+_208103068 2.367 CREB1
cAMP responsive element binding protein 1
chr5_-_138238891 2.367 CTNNA1
LRRTM2
catenin (cadherin-associated protein), alpha 1, 102kDa
leucine rich repeat transmembrane neuronal 2
chr20_+_33667160 2.341 NM_003116
SPAG4
sperm associated antigen 4
chr10_+_93673485 2.324 BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
chr2_-_241860923 2.314 NM_203346
HDLBP
high density lipoprotein binding protein
chr14_-_22458199 2.214 RBM23
RNA binding motif protein 23
chr2_+_28469199 2.204 FOSL2
FOS-like antigen 2
chr2_-_241860917 2.198 HDLBP
high density lipoprotein binding protein
chr2_-_241860871 2.181 HDLBP
high density lipoprotein binding protein
chr14_-_22458134 2.180 RBM23
RNA binding motif protein 23
chr14_-_38971049 2.177 FBXO33
F-box protein 33
chr12_+_70120028 2.176 NM_003667
LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr2_+_118288724 2.176 NM_006773
DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr5_-_138238877 2.172 LRRTM2
leucine rich repeat transmembrane neuronal 2
chr2_+_118288753 2.157 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_-_159021201 2.152 NM_001171637
NM_138803
CCDC148

coiled-coil domain containing 148

chr21_+_33837233 2.142 SON
SON DNA binding protein
chr5_-_95794416 2.120 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr1_+_161027115 2.118 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr21_-_33836994 2.108 NM_001136005
NM_001136006
GART

phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase

chr17_+_55052060 2.108 CLTC
clathrin, heavy chain (Hc)
chr22_+_36927884 2.101 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr11_+_18372682 2.101 LDHA
lactate dehydrogenase A
chr17_+_55052046 2.073 CLTC
clathrin, heavy chain (Hc)
chr21_+_33837215 2.067 NM_032195
NM_138927
SON

SON DNA binding protein

chr12_+_70434920 2.062 NM_014999
RAB21
RAB21, member RAS oncogene family
chr2_+_208103001 2.062 CREB1
cAMP responsive element binding protein 1
chr2_-_234317362 2.059 NM_001001394
DNAJB3
DnaJ (Hsp40) homolog, subfamily B, member 3
chr21_+_33837212 2.056 SON
SON DNA binding protein
chr15_+_91248706 2.050 CHD2
chromodomain helicase DNA binding protein 2
chr5_-_138238953 2.045 NM_015564
LRRTM2
leucine rich repeat transmembrane neuronal 2
chr8_-_17148637 2.042 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr12_+_70119785 2.040 LGR5
leucine-rich repeat containing G protein-coupled receptor 5
chr14_+_34521945 2.039 SRP54
signal recognition particle 54kDa
chr17_+_37098652 2.037 NM_005801
EIF1
eukaryotic translation initiation factor 1
chr2_+_60962206 2.022 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr2_+_118288754 2.014 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr17_+_37098667 2.010 EIF1
eukaryotic translation initiation factor 1
chr3_+_23962518 2.000 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr11_+_18372687 1.990 LDHA
lactate dehydrogenase A
chr11_+_18372689 1.945 LDHA
lactate dehydrogenase A
chr14_-_22458220 1.931 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr17_+_55052065 1.931 CLTC
clathrin, heavy chain (Hc)
chr11_+_18372708 1.906 LDHA
lactate dehydrogenase A
chr2_+_60962279 1.904 REL
v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr2_+_62787534 1.901 NM_001142614
EHBP1
EH domain binding protein 1
chr17_+_55052185 1.863


chr2_+_177785667 1.854 NM_194247
HNRNPA3P1
HNRNPA3
heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
heterogeneous nuclear ribonucleoprotein A3
chr17_+_50697355 1.846 HLF
hepatic leukemia factor
chr3_+_102775677 1.836 PCNP
PEST proteolytic signal containing nuclear protein
chr17_+_77780177 1.834 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr3_+_142569988 1.815 ZBTB38
zinc finger and BTB domain containing 38
chr8_-_17148474 1.809 CNOT7
CCR4-NOT transcription complex, subunit 7
chr8_+_17148755 1.808 NM_001145152
NM_152415
VPS37A

vacuolar protein sorting 37 homolog A (S. cerevisiae)

chr14_-_38971370 1.806 NM_203301
FBXO33
F-box protein 33
chr14_+_34521854 1.805 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr3_+_142143329 1.790 NM_001104647
NM_018155
SLC25A36

solute carrier family 25, member 36

chr21_+_37661063 1.784 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr10_+_93673544 1.763 NM_003972
BTAF1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa (Mot1 homolog, S. cerevisiae)
chr6_+_138230045 1.753 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr17_+_2443652 1.743 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr20_+_39091026 1.742 TOP1
topoisomerase (DNA) I
chr17_+_37098668 1.735 EIF1
eukaryotic translation initiation factor 1
chr16_+_49139694 1.719 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr20_+_18436167 1.718 NM_006363
NM_032985
NM_032986
NM_001172746
SEC23B



Sec23 homolog B (S. cerevisiae)



chr17_+_50697319 1.710 NM_002126
HLF
hepatic leukemia factor
chr2_+_8739563 1.699 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr14_+_69303614 1.693 SRSF5
serine/arginine-rich splicing factor 5
chr2_+_170149348 1.692 PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr14_+_69303633 1.686 SRSF5
serine/arginine-rich splicing factor 5
chr14_+_69303615 1.683 SRSF5
serine/arginine-rich splicing factor 5
chr20_+_18436548 1.680 NM_001172745
SEC23B
Sec23 homolog B (S. cerevisiae)
chr3_+_101462375 1.656 NM_018309
TBC1D23
TBC1 domain family, member 23
chr15_+_78139073 1.655 NM_019006
ZFAND6
zinc finger, AN1-type domain 6
chr20_+_10147455 1.649 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr17_+_64019693 1.647 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr20_+_39090875 1.626 NM_003286
TOP1
topoisomerase (DNA) I
chr16_+_415606 1.623 RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr18_+_75968133 1.620 ADNP2
ADNP homeobox 2
chr4_+_85723080 1.620 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr18_+_75967902 1.616 NM_014913
ADNP2
ADNP homeobox 2
chr2_+_131579355 1.614 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr5_+_78568094 1.606


chr1_+_99502655 1.600 LPPR4
lipid phosphate phosphatase-related protein type 4
chr2_+_30223304 1.598 YPEL5
yippee-like 5 (Drosophila)
chr2_+_30223253 1.588 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr15_+_78139018 1.577 ZFAND6
zinc finger, AN1-type domain 6
chr3_+_73128629 1.577 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr15_+_78139098 1.566 ZFAND6
zinc finger, AN1-type domain 6
chr20_+_34635362 1.561 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr8_+_22280731 1.557 SLC39A14
solute carrier family 39 (zinc transporter), member 14
chr3_+_43303005 1.549 NM_001100594
NM_017719
SNRK

SNF related kinase

chr4_+_144654005 1.539 NM_003601
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_+_78567604 1.536 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr8_+_22280703 1.532 NM_001128431
NM_001135154
NM_015359
SLC39A14


solute carrier family 39 (zinc transporter), member 14


chr2_+_233270286 1.530 GIGYF2
GRB10 interacting GYF protein 2
chr3_+_73128667 1.530 PPP4R2
protein phosphatase 4, regulatory subunit 2
chr20_+_41519882 1.530 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr2_+_28828332 1.529 PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr14_+_99774854 1.528 NM_003403
YY1
YY1 transcription factor
chr20_+_18436525 1.516 SEC23B
Sec23 homolog B (S. cerevisiae)
chr11_+_101723157 1.506 NM_001166
BIRC2
baculoviral IAP repeat containing 2
chr20_-_34635091 1.503


chr22_+_36928011 1.499 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr20_-_33329319 1.494 EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr11_+_101723125 1.492 BIRC2
baculoviral IAP repeat containing 2
chr20_+_36534871 1.488 NM_020336
RALGAPB
Ral GTPase activating protein, beta subunit (non-catalytic)
chr14_+_31100330 1.488 NM_025152
NUBPL
nucleotide binding protein-like
chr8_+_61753793 1.477 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr12_+_97511805 1.471 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr12_+_67290951 1.467 RAP1B
RAP1BL
RAP1B, member of RAS oncogene family
RAP1B, member of RAS oncogene family pseudogene
chr1_+_212227902 1.459 PROX1
prospero homeobox 1
chr2_+_131579334 1.456 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr3_+_73128771 1.452 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr14_+_69303565 1.438 NM_001039465
NM_006925
SRSF5

serine/arginine-rich splicing factor 5

chr20_+_41519947 1.438 SRSF6
serine/arginine-rich splicing factor 6
chr16_+_415630 1.428 NM_014700
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr14_+_54588151 1.416 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr2_+_233270275 1.412 GIGYF2
GRB10 interacting GYF protein 2
chr2_+_187059115 1.404 NM_018471
ZC3H15
zinc finger CCCH-type containing 15
chr4_-_120595218 1.398


chr8_+_26204997 1.396 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr17_+_38831874 1.392 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr11_+_18372493 1.390 NM_001135239
NM_001165415
NM_001165416
NM_005566
LDHA



lactate dehydrogenase A



chr7_+_6111115 1.381 USP42
ubiquitin specific peptidase 42
chr2_+_207215386 1.377 NM_001102659
LOC200726
hCG1657980
chr5_+_112877251 1.376 NM_022828
YTHDC2
YTH domain containing 2
chr17_+_64019748 1.368 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr8_+_26204921 1.365 NM_002717
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr2_+_233270241 1.356 NM_001103146
NM_001103147
NM_001103148
NM_015575
GIGYF2



GRB10 interacting GYF protein 2



chr14_-_35859545 1.355 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr11_+_110978309 1.350 NM_015191
SIK2
salt-inducible kinase 2
chr6_+_47553399 1.342 NM_012120
CD2AP
CD2-associated protein
chr2_+_170149092 1.337 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr3_+_171167243 1.335 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr2_+_208102937 1.334 CREB1
cAMP responsive element binding protein 1
chr2_+_187059277 1.330 ZC3H15
zinc finger CCCH-type containing 15
chr7_+_39956128 1.325 CDK13
cyclin-dependent kinase 13
chr14_+_54588138 1.324 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr12_+_97511585 1.322 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr16_+_55523526 1.318 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr1_+_51855343 1.316 OSBPL9
oxysterol binding protein-like 9
chr14_+_54588125 1.315 MAPK1IP1L
mitogen-activated protein kinase 1 interacting protein 1-like
chr12_+_97511596 1.313 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr20_+_17897529 1.311 NM_052865
C20orf72
chromosome 20 open reading frame 72
chr12_+_97511569 1.306 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr8_+_26204960 1.305 PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr12_+_67290977 1.304 RAP1B
RAP1BL
RAP1B, member of RAS oncogene family
RAP1B, member of RAS oncogene family pseudogene
chr19_+_50041400 1.286 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr5_-_72896964 1.283 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr10_+_38685299 1.281 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr12_+_97511594 1.275 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr2_+_107969410 1.272 NM_021815
SLC5A7
solute carrier family 5 (choline transporter), member 7
chr7_+_7188667 1.266 NM_020156
C1GALT1
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1
chr12_+_67290975 1.260 RAP1B
RAP1B, member of RAS oncogene family
chr8_+_61592278 1.260 RAB2A
RAB2A, member RAS oncogene family
chr3_+_129253977 1.258 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr16_+_18986721 1.251 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr12_+_97511520 1.248 NM_002635
NM_005888
NM_213611
SLC25A3


solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3


chr2_+_187059237 1.244 ZC3H15
zinc finger CCCH-type containing 15
chr12_+_67291016 1.239 RAP1B
RAP1B, member of RAS oncogene family
chr5_-_72897132 1.234 NM_023039
ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr20_+_29656744 1.233 NM_002165
NM_181353
ID1

inhibitor of DNA binding 1, dominant negative helix-loop-helix protein

chr17_-_13445942 1.225 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr14_+_69303563 1.217 SRSF5
serine/arginine-rich splicing factor 5
chr4_+_144654526 1.217


chr12_+_97511631 1.215 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr7_+_6111030 1.215 NM_032172
USP42
ubiquitin specific peptidase 42
chr9_-_72063559 1.214 LOC100507299
hypothetical LOC100507299
chr19_+_62593142 1.213 ZNF548
ZNF17
zinc finger protein 548
zinc finger protein 17
chr15_+_70553719 1.207 NM_005744
ARIH1
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 5.31e-18 GO:0044260 cellular macromolecule metabolic process
1.29 1.61e-14 GO:0044237 cellular metabolic process
1.34 5.08e-14 GO:0043170 macromolecule metabolic process
1.55 4.97e-10 GO:0010467 gene expression
1.24 1.67e-09 GO:0044238 primary metabolic process
1.21 2.06e-09 GO:0008152 metabolic process
1.43 1.10e-08 GO:0044267 cellular protein metabolic process
1.53 4.34e-08 GO:0009059 macromolecule biosynthetic process
1.52 6.79e-08 GO:0034645 cellular macromolecule biosynthetic process
1.12 3.44e-07 GO:0009987 cellular process
1.48 7.30e-07 GO:0016070 RNA metabolic process
1.40 7.31e-07 GO:0044249 cellular biosynthetic process
1.39 7.79e-07 GO:0009058 biosynthetic process
1.41 1.42e-06 GO:0090304 nucleic acid metabolic process
1.32 5.43e-06 GO:0034641 cellular nitrogen compound metabolic process
1.54 6.02e-06 GO:0051641 cellular localization
1.34 8.81e-06 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.69 1.65e-05 GO:0046907 intracellular transport
1.30 1.70e-05 GO:0006807 nitrogen compound metabolic process
1.55 4.22e-05 GO:0051649 establishment of localization in cell
1.31 5.56e-05 GO:0019538 protein metabolic process
1.62 8.94e-05 GO:0006351 transcription, DNA-dependent
1.54 7.30e-04 GO:0032774 RNA biosynthetic process
1.37 1.12e-03 GO:0006464 protein modification process
1.34 3.93e-03 GO:0043412 macromolecule modification
1.29 5.23e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.52 6.73e-03 GO:0045184 establishment of protein localization
1.40 9.59e-03 GO:0033036 macromolecule localization
1.27 1.07e-02 GO:0031326 regulation of cellular biosynthetic process
1.27 1.67e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.27 1.97e-02 GO:0010468 regulation of gene expression
1.26 2.01e-02 GO:0009889 regulation of biosynthetic process
1.49 2.17e-02 GO:0015031 protein transport
1.43 2.56e-02 GO:0008104 protein localization
1.57 2.67e-02 GO:0006396 RNA processing
1.28 3.56e-02 GO:0051252 regulation of RNA metabolic process
3.61 3.63e-02 GO:0006888 ER to Golgi vesicle-mediated transport
1.28 4.30e-02 GO:0006355 regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.21 3.48e-16 GO:0043227 membrane-bounded organelle
1.21 5.79e-16 GO:0043231 intracellular membrane-bounded organelle
1.15 6.52e-16 GO:0044424 intracellular part
1.14 2.99e-14 GO:0005622 intracellular
1.18 3.24e-14 GO:0043229 intracellular organelle
1.18 4.12e-14 GO:0043226 organelle
1.28 7.43e-13 GO:0044422 organelle part
1.28 1.15e-12 GO:0044446 intracellular organelle part
1.18 2.09e-10 GO:0005737 cytoplasm
1.45 4.31e-09 GO:0044428 nuclear part
1.43 1.03e-08 GO:0043233 organelle lumen
1.43 1.08e-08 GO:0070013 intracellular organelle lumen
1.48 1.49e-08 GO:0031981 nuclear lumen
1.42 1.70e-08 GO:0031974 membrane-enclosed lumen
1.23 3.04e-08 GO:0005634 nucleus
1.20 1.72e-06 GO:0044444 cytoplasmic part
1.47 2.78e-05 GO:0005654 nucleoplasm
1.65 7.21e-05 GO:0015630 microtubule cytoskeleton
1.53 3.22e-03 GO:0044451 nucleoplasm part
2.39 3.23e-03 GO:0016607 nuclear speck
1.39 1.43e-02 GO:0005783 endoplasmic reticulum
1.72 1.99e-02 GO:0005815 microtubule organizing center
1.19 2.35e-02 GO:0032991 macromolecular complex
1.26 3.71e-02 GO:0005829 cytosol
1.39 3.79e-02 GO:0005794 Golgi apparatus
1.20 4.73e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.22 6.19e-12 GO:0005515 protein binding
1.12 3.18e-10 GO:0005488 binding
1.37 1.98e-06 GO:0000166 nucleotide binding
1.41 3.79e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.41 4.49e-06 GO:0032553 ribonucleotide binding
1.41 4.49e-06 GO:0032555 purine ribonucleotide binding
1.41 4.82e-06 GO:0017076 purine nucleotide binding
1.57 2.17e-04 GO:0003723 RNA binding
1.25 5.28e-04 GO:0003676 nucleic acid binding
1.38 1.01e-03 GO:0030554 adenyl nucleotide binding
1.38 1.04e-03 GO:0032559 adenyl ribonucleotide binding
1.38 1.26e-03 GO:0005524 ATP binding