Motif ID: HNF4A_NR2F1,2.p2

Z-value: 3.830


Transcription factors associated with HNF4A_NR2F1,2.p2:

Gene SymbolEntrez IDGene Name
HNF4A 3172 hepatocyte nuclear factor 4, alpha
NR2F1 7025 nuclear receptor subfamily 2, group F, member 1
NR2F2 7026 nuclear receptor subfamily 2, group F, member 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR2F2chr15_+_94676691-0.495.2e-02Click!
NR2F1chr5_+_92944680-0.224.1e-01Click!
HNF4Achr20_+_424633870.146.0e-01Click!


Activity profile for motif HNF4A_NR2F1,2.p2.

activity profile for motif HNF4A_NR2F1,2.p2


Sorted Z-values histogram for motif HNF4A_NR2F1,2.p2

Sorted Z-values for motif HNF4A_NR2F1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF4A_NR2F1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_34554800 6.886 CNTFR
ciliary neurotrophic factor receptor
chr6_+_29799095 4.042 NM_001098478
NM_001098479
NM_018950
 HLA-F


major histocompatibility complex, class I, F


chr6_+_29799182 3.784 HLA-F
major histocompatibility complex, class I, F
chr2_-_241480058 3.653 NM_024861
 C2orf54
chromosome 2 open reading frame 54
chr9_+_126253243 3.455 NM_001161808
 GPR144
G protein-coupled receptor 144
chr19_+_44308224 3.421 NM_001014831
NM_001014832
NM_001014834
NM_001014835
NM_005884
 PAK4




p21 protein (Cdc42/Rac)-activated kinase 4




chr3_-_46879883 3.413 NM_000258
 MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr6_+_37081387 3.287 NM_173558
 FGD2
FYVE, RhoGEF and PH domain containing 2
chr21_+_44169706 3.245 NM_001037553
 AGPAT3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr22_-_22970850 3.205 NM_001099781
NM_001099782
NM_004121
 GGT5


gamma-glutamyltransferase 5


chr9_-_129752687 3.048 NM_203305
 FAM102A
family with sequence similarity 102, member A
chr7_-_150515410 3.024 NM_001142459
NM_001142460
 ASB10

ankyrin repeat and SOCS box containing 10

chr16_+_3642940 2.889 NM_005223
 DNASE1
deoxyribonuclease I
chr16_+_2954217 2.885 NM_024507
NM_172229
 KREMEN2

kringle containing transmembrane protein 2

chr20_-_61462960 2.881 NM_000744
 CHRNA4
cholinergic receptor, nicotinic, alpha 4
chr19_+_5082230 2.818 KDM4B
lysine (K)-specific demethylase 4B
chr1_+_9222489 2.792 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr3_+_9666198 2.785 MTMR14
myotubularin related protein 14
chr19_-_1062972 2.767 SBNO2
strawberry notch homolog 2 (Drosophila)
chrX_-_48655978 2.753 PIM2
pim-2 oncogene

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
3.83 1.35e-02 GO:0006942 regulation of striated muscle contraction
1.65 4.73e-02 GO:0030029 actin filament-based process
1.29 1.50e-05 GO:0042221 response to chemical stimulus
1.24 9.29e-03 GO:0065008 regulation of biological quality
1.11 4.69e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.05 2.42e-02 GO:0030017 sarcomere
1.70 8.67e-04 GO:0015629 actin cytoskeleton
1.41 6.22e-04 GO:0005626 insoluble fraction
1.41 7.56e-04 GO:0005624 membrane fraction
1.30 1.69e-02 GO:0000267 cell fraction
1.24 5.69e-04 GO:0044459 plasma membrane part

Nothing significant found in function category.