Motif ID: NKX2-2,8.p2

Z-value: 2.217


Transcription factors associated with NKX2-2,8.p2:

Gene SymbolEntrez IDGene Name
NKX2-2 4821 NK2 homeobox 2
NKX2-8 26257 NK2 homeobox 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-2chr20_-_21442663-0.332.1e-01Click!
NKX2-8chr14_-_361215360.048.9e-01Click!


Activity profile for motif NKX2-2,8.p2.

activity profile for motif NKX2-2,8.p2


Sorted Z-values histogram for motif NKX2-2,8.p2

Sorted Z-values for motif NKX2-2,8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-2,8.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_88573949 3.438 NM_001001323
NM_001682
 ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr10_-_98326435 3.060 TM9SF3
transmembrane 9 superfamily member 3
chr2_+_228064531 2.910 AGFG1
ArfGAP with FG repeats 1
chr4_+_95595419 2.767 PDLIM5
PDZ and LIM domain 5
chr7_+_111879348 2.723 NM_001197079
 IFRD1
interferon-related developmental regulator 1
chr2_-_225078931 2.663 CUL3
cullin 3
chr17_-_26648375 2.559 NM_002544
 OMG
oligodendrocyte myelin glycoprotein
chr3_-_153541468 2.346 NM_001123228
 TMEM14E
transmembrane protein 14E
chr1_+_213245507 2.224 NM_001017424
 KCNK2
potassium channel, subfamily K, member 2
chr13_-_40454188 2.201 ELF1
E74-like factor 1 (ets domain transcription factor)
chr9_+_122923864 2.002 CEP110
centrosomal protein 110kDa
chr12_+_63090008 1.954 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr8_+_32698892 1.922 NM_001159996
 NRG1
neuregulin 1
chr18_-_65766068 1.876 CD226
CD226 molecule
chr12_-_44877769 1.838 SLC38A1
solute carrier family 38, member 1
chr3_+_190990142 1.807 NM_001114980
NM_001114981
NM_001114982
 TP63


tumor protein p63


chr1_+_169747788 1.780 PRRC2C
proline-rich coiled-coil 2C
chr1_+_84402962 1.767 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr11_+_12917369 1.736 TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr3_+_160473784 1.689 SCHIP1
schwannomin interacting protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.23 1.93e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.64 1.36e-02 GO:0005626 insoluble fraction
1.44 2.38e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.68 9.38e-03 GO:0004930 G-protein coupled receptor activity