Motif ID: NFIX.p2

Z-value: 1.626


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFIXchr19_+_130669560.665.0e-03Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_71613472 3.964 NM_001567
INPPL1
inositol polyphosphate phosphatase-like 1
chr12_+_48641545 1.667 NM_001651
AQP5
aquaporin 5
chr10_+_17312654 1.631 VIM
vimentin
chr12_+_50271283 1.533 NM_014191
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr19_-_1188840 1.518 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr13_+_27392136 1.499 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr21_+_44941514 1.474 NM_198699
KRTAP10-12
keratin associated protein 10-12
chr17_-_25587079 1.437 NM_001045
SLC6A4
solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
chr1_+_226741665 1.386 NM_001010858
RNF187
ring finger protein 187
chr1_+_891739 1.342 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr1_+_226261374 1.335 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr9_-_139183675 1.311


chr21_-_44836811 1.220 NM_198688
KRTAP10-6
keratin associated protein 10-6
chr6_+_150326802 1.214 NM_025218
ULBP1
UL16 binding protein 1
chr17_+_17952744 1.186 NM_016239
MYO15A
myosin XVA
chr4_+_191229360 1.086 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr17_+_18069593 1.082 NM_004140
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chrX_-_135941498 1.050 NM_054021
GPR101
G protein-coupled receptor 101
chr7_-_100630912 0.988 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr16_+_3002457 0.985 NM_020982
CLDN9
claudin 9
chr9_-_73573121 0.985 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chrX_+_10084984 0.973 NM_001830
CLCN4
chloride channel 4
chr10_+_17311788 0.950 VIM
vimentin
chr10_+_102782151 0.949 SFXN3
sideroflexin 3
chr18_+_70352779 0.923 CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr19_-_18246166 0.911 NM_001145304
NM_001145305
NM_025249
KIAA1683


KIAA1683


chr10_+_17311962 0.907 VIM
vimentin
chr6_-_119512035 0.903 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr11_-_72031083 0.902 NM_001143839
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr1_+_6188727 0.888 NM_207396
RNF207
ring finger protein 207
chr12_-_97421753 0.884 LOC643770
hypothetical LOC643770
chr1_+_155157047 0.881 NM_144702
LRRC71
leucine rich repeat containing 71
chr1_+_1062137 0.876 LOC254099
hypothetical protein LOC254099
chr22_+_37193961 0.874 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr10_-_17311961 0.869


chr9_+_139047441 0.865 C9orf139
chromosome 9 open reading frame 139
chr15_+_65217412 0.861 NM_001145103
SMAD3
SMAD family member 3
chr1_+_154449389 0.859 NM_007221
PMF1-BGLAP
PMF1
PMF1-BGLAP read-through transcript
polyamine-modulated factor 1
chr21_-_43671355 0.854 NM_173354
SIK1
salt-inducible kinase 1
chr11_-_118286822 0.842 NM_182557
BCL9L
B-cell CLL/lymphoma 9-like
chr17_-_23716391 0.841 NM_001080837
SEBOX
SEBOX homeobox
chr19_+_51498695 0.839 NM_152794
HIF3A
hypoxia inducible factor 3, alpha subunit
chr11_-_67163600 0.832 NM_005995
TBX10
T-box 10
chr18_+_70352649 0.830 NM_032649
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chrX_+_124281649 0.818 NM_001195272
LOC100129520
testis expressed sequence 13-like
chr9_+_111850770 0.817 AKAP2
A kinase (PRKA) anchor protein 2
chr2_+_241023880 0.810


chr21_+_44818033 0.803 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr11_+_63815348 0.802 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr8_-_142307854 0.798 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr1_+_41022066 0.796 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr19_-_11234117 0.768 NM_020812
DOCK6
dedicator of cytokinesis 6
chr1_+_226394638 0.760 GUK1
guanylate kinase 1
chr22_-_39923412 0.759


chr5_+_154072654 0.758 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr16_-_695719 0.758 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr16_+_65765256 0.754 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr16_+_31401939 0.753 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr21_+_33364316 0.751 NM_138983
OLIG1
oligodendrocyte transcription factor 1
chr19_-_8118367 0.749 NM_032447
FBN3
fibrillin 3
chr19_-_19599973 0.746 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr1_+_226394626 0.742 GUK1
guanylate kinase 1
chr1_+_226394605 0.736 GUK1
guanylate kinase 1
chr1_-_1840564 0.735 NM_178545
TMEM52
transmembrane protein 52
chr9_+_111850698 0.726 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr17_-_77868659 0.715 NM_006137
CD7
CD7 molecule
chr16_+_2954217 0.710 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr21_-_44795769 0.703 NM_198693
KRTAP10-2
keratin associated protein 10-2
chr21_+_44844924 0.693 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr8_-_33544184 0.686 NM_024787
RNF122
ring finger protein 122
chr2_+_241023703 0.685 NM_002081
GPC1
glypican 1
chr17_+_21220260 0.661 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr19_+_51797167 0.661 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr1_+_226394589 0.661 GUK1
guanylate kinase 1
chr2_+_11804190 0.659 NM_145693
LPIN1
lipin 1
chr9_+_139091759 0.656 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr1_+_226394545 0.656 NM_000858
NM_001159390
GUK1

guanylate kinase 1

chr5_+_148766632 0.654 LOC728264
hypothetical LOC728264
chr5_-_1687099 0.654 LOC728613
programmed cell death 6 pseudogene
chr1_+_46632505 0.647 NM_001441
FAAH
fatty acid amide hydrolase
chrX_-_100070553 0.644 NM_212559
XKRX
XK, Kell blood group complex subunit-related, X-linked
chr16_+_29892714 0.644 NM_004783
NM_016151
TAOK2

TAO kinase 2

chr10_+_124210980 0.637 NM_002775
HTRA1
HtrA serine peptidase 1
chr4_-_85638410 0.636 NM_006168
NKX6-1
NK6 homeobox 1
chr8_+_144428083 0.631 GLI4
GLI family zinc finger 4
chr12_+_106236281 0.631 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr5_+_132111034 0.630 NM_001039780
CCNI2
cyclin I family, member 2
chr12_-_120715937 0.627 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr13_-_97972252 0.626 NM_003576
STK24
serine/threonine kinase 24
chr1_+_1250152 0.624


chr19_+_18803742 0.623 NM_002911
UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
chr10_-_105982052 0.622 NM_025145
WDR96
WD repeat domain 96
chr1_+_29011240 0.619 NM_000911
OPRD1
opioid receptor, delta 1
chr17_+_7225088 0.618 NM_003985
TNK1
tyrosine kinase, non-receptor, 1
chr7_+_1063666 0.616 NM_138445
GPR146
G protein-coupled receptor 146
chr22_+_23309717 0.611 NM_013430
GGT1
gamma-glutamyltransferase 1
chr19_+_51804260 0.606 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr12_+_107433179 0.605 NM_007076
FICD
FIC domain containing
chr1_+_156417302 0.603 CD1D
CD1d molecule
chr1_+_238321794 0.601 NM_020066
FMN2
formin 2
chr21_-_42247007 0.600 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chrX_+_53139936 0.596 LOC100132984
hypothetical protein LOC100132984
chr10_+_11824361 0.595 NM_024693
ECHDC3
enoyl CoA hydratase domain containing 3
chr8_+_22465368 0.588 SORBS3
sorbin and SH3 domain containing 3
chr17_-_25112393 0.577 SSH2
slingshot homolog 2 (Drosophila)
chr11_-_3210191 0.575 NM_001039165
MRGPRE
MAS-related GPR, member E
chr3_+_185762233 0.569 NM_004443
EPHB3
EPH receptor B3
chr1_-_21821597 0.568 RAP1GAP
RAP1 GTPase activating protein
chr9_+_139092016 0.566 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr9_+_77695334 0.562 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr9_-_129707392 0.560 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_+_199975674 0.558 NAV1
neuron navigator 1
chr1_+_1250115 0.556 GLTPD1
glycolipid transfer protein domain containing 1
chr19_+_60816770 0.554 NM_001195605
ZNF865
zinc finger protein 865
chr17_+_19222651 0.553 MAPK7
mitogen-activated protein kinase 7
chr1_+_16131633 0.552


chr1_-_46789473 0.545 NM_001097611
KNCN
kinocilin
chr3_-_49916304 0.544 NM_002447
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr8_-_68037378 0.543 NM_001193502
TCF24
transcription factor 24
chr11_+_113280727 0.543 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr3_-_46710137 0.540 NM_001190707
NM_147129
ALS2CL

ALS2 C-terminal like

chr14_+_102458745 0.532 NM_030943
AMN
amnionless homolog (mouse)
chr15_-_41346346 0.528 NM_004245
NM_201631
TGM5

transglutaminase 5

chr12_+_6179736 0.527 NM_001769
CD9
CD9 molecule
chr11_-_117203937 0.526 NM_021603
FXYD2
FXYD domain containing ion transport regulator 2
chr10_+_88718167 0.523 NM_006829
C10orf116
chromosome 10 open reading frame 116
chr1_+_36394338 0.522 NM_018067
MAP7D1
MAP7 domain containing 1
chr3_-_46481346 0.519 NM_002343
LTF
lactotransferrin
chr1_+_199975563 0.516 NM_001167738
NAV1
neuron navigator 1
chr4_-_25473528 0.516 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_150233337 0.515 NM_002966
S100A10
S100 calcium binding protein A10
chr22_+_28446288 0.511 NM_182527
CABP7
calcium binding protein 7
chr22_-_48604455 0.508 NM_014577
BRD1
bromodomain containing 1
chr19_-_1993022 0.507 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_-_1687040 0.503 LOC728613
programmed cell death 6 pseudogene
chr19_-_15869870 0.502 NM_001082
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr22_+_49266836 0.497 NM_024866
ADM2
adrenomedullin 2
chr1_-_112083387 0.497 NM_019099
C1orf183
chromosome 1 open reading frame 183
chr16_+_2820173 0.495 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr14_+_104338423 0.493 ZBTB42
zinc finger and BTB domain containing 42
chrX_-_68301974 0.489 NM_001032396
NM_022368
NM_145119
PJA1


praja ring finger 1


chr9_+_35595339 0.487 TESK1
testis-specific kinase 1
chr22_+_48971067 0.487 TRABD
TraB domain containing
chr19_+_53664276 0.487 NM_004228
NM_017457
CYTH2

cytohesin 2

chr12_+_62523648 0.487


chr18_-_5286013 0.484 NM_001143823
NM_003409
ZFP161

zinc finger protein 161 homolog (mouse)

chr8_-_82916982 0.481 NM_022133
NM_152836
NM_152837
SNX16


sorting nexin 16


chr10_+_45542653 0.478 NM_001169106
NM_001169107
NM_015262
FAM21C


FAM21A
family with sequence similarity 21, member C


family with sequence similarity 21, member A
chr1_-_150232900 0.475 S100A10
S100 calcium binding protein A10
chr1_-_36008009 0.474 NM_001190481
NM_022111
CLSPN

claspin

chr14_+_104785936 0.471 BTBD6
BTB (POZ) domain containing 6
chr1_-_6243621 0.470 NM_207370
GPR153
G protein-coupled receptor 153
chr9_-_139047112 0.470 NM_004479
FUT7
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
chr19_+_54682676 0.466 NM_012423
RPL13A
ribosomal protein L13a
chr15_-_70455153 0.465 HEXA
hexosaminidase A (alpha polypeptide)
chr19_-_53808505 0.464 NM_017708
FAM83E
family with sequence similarity 83, member E
chr21_-_45786709 0.461 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr19_+_48808092 0.459 NM_001145641
SRRM5
serine/arginine repetitive matrix 5
chr19_-_3752809 0.456 NM_002378
MATK
megakaryocyte-associated tyrosine kinase
chr6_-_109868400 0.455 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr1_+_77105746 0.455 NM_030965
ST6GALNAC5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
chr11_+_125262164 0.455 NM_001134793
HYLS1
hydrolethalus syndrome 1
chr10_+_134972902 0.455


chrX_+_67784235 0.454 NM_001142503
NM_014725
STARD8

StAR-related lipid transfer (START) domain containing 8

chr17_+_59429442 0.453 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr15_-_20929608 0.451 HERC2P2
hect domain and RLD 2 pseudogene 2
chr17_+_19221606 0.450 NM_139032
NM_139033
MAPK7

mitogen-activated protein kinase 7

chr19_+_46286207 0.450 NM_000766
CYP2A13
cytochrome P450, family 2, subfamily A, polypeptide 13
chr17_+_35587767 0.448 NM_016339
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chrX_-_20044670 0.448 NM_001168467
MAP7D2
MAP7 domain containing 2
chr1_-_150232927 0.448 S100A10
S100 calcium binding protein A10
chr21_+_42807052 0.448 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr15_-_70455355 0.447 NM_000520
HEXA
hexosaminidase A (alpha polypeptide)
chr20_-_61669550 0.445 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr5_+_34720368 0.444 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr3_+_101536234 0.444 NM_020202
NIT2
nitrilase family, member 2
chr8_+_38950824 0.444 NM_153692
HTRA4
HtrA serine peptidase 4
chr5_-_59819642 0.442 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_+_151975518 0.440 PNMA3
paraneoplastic antigen MA3
chrX_+_71047344 0.438 NM_001013627
NHSL2
NHS-like 2
chr17_-_53387493 0.433 CUEDC1
CUE domain containing 1
chr3_-_126215069 0.432 HEG1
HEG homolog 1 (zebrafish)
chr2_-_241484245 0.430 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr10_+_135057597 0.429 NM_138384
MTG1
mitochondrial GTPase 1 homolog (S. cerevisiae)
chr11_-_1464386 0.427 NM_001172223
MOB2
Mps one binder kinase activator-like 2
chr1_+_32447281 0.427 NM_001099434
DCDC2B
doublecortin domain containing 2B
chr9_-_129782624 0.424 NM_001035254
FAM102A
family with sequence similarity 102, member A
chr11_-_64582568 0.424 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr1_+_226399026 0.423 NM_001159391
GUK1
guanylate kinase 1
chr16_+_658081 0.423 NM_138769
RHOT2
ras homolog gene family, member T2
chr9_+_138966588 0.422 NM_178536
LCN12
lipocalin 12
chr15_+_89570333 0.422 SV2B
synaptic vesicle glycoprotein 2B
chrX_+_151975421 0.421 NM_013364
PNMA3
paraneoplastic antigen MA3
chr16_+_88169612 0.421 NM_014427
NM_153636
CPNE7

copine VII

chr22_-_35233032 0.420 NM_024955
NM_001102371
FOXRED2

FAD-dependent oxidoreductase domain containing 2

chr5_+_140767953 0.420 NM_018926
NM_032100
PCDHGB6

protocadherin gamma subfamily B, 6

chr1_+_43386180 0.417 NM_001101376
FAM183A
family with sequence similarity 183, member A
chr5_-_54558899 0.417 NM_001190787
LOC345643
hypothetical LOC345643
chr4_-_1827475 0.415 NM_012318
LETM1
leucine zipper-EF-hand containing transmembrane protein 1
chr4_+_155707089 0.413 FGB
fibrinogen beta chain

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 3.09e-02 GO:0005737 cytoplasm
1.13 4.70e-02 GO:0044444 cytoplasmic part

Nothing significant found in function category.