Motif ID: PAX6.p2

Z-value: 0.564


Transcription factors associated with PAX6.p2:

Gene SymbolEntrez IDGene Name
PAX6 5080 paired box 6

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX6chr11_-_317821690.504.8e-02Click!


Activity profile for motif PAX6.p2.

activity profile for motif PAX6.p2


Sorted Z-values histogram for motif PAX6.p2

Sorted Z-values for motif PAX6.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX6.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_72761367 1.342 STX1A
syntaxin 1A (brain)
chr1_+_93830106 1.056 LOC100129046
hypothetical LOC100129046
chr7_+_154943466 0.943 NM_001427
EN2
engrailed homeobox 2
chr1_+_93830169 0.828 LOC100129046
hypothetical LOC100129046
chrX_-_123925343 0.706 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr16_+_70646008 0.651 NM_001126102
NM_005143
HP

haptoglobin

chr22_+_38075703 0.564 NM_004711
NM_145731
SYNGR1

synaptogyrin 1

chr15_+_49760841 0.460 NM_001165257
NM_013243
SCG3

secretogranin III

chr10_+_118340460 0.425 NM_006229
PNLIPRP1
pancreatic lipase-related protein 1
chr4_+_70896236 0.399 NM_001009181
NM_003154
STATH

statherin

chr5_-_135259403 0.391 NM_000590
IL9
interleukin 9
chr1_+_113038202 0.373 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chrX_-_53478016 0.322 NM_001037811
NM_004493
HSD17B10

hydroxysteroid (17-beta) dehydrogenase 10

chr3_+_52212969 0.315 ALAS1
aminolevulinate, delta-, synthase 1
chr10_-_82039158 0.288 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chrX_-_65176564 0.277 NM_001100431
NM_001184830
NM_001184831
NM_007268
VSIG4



V-set and immunoglobulin domain containing 4



chr9_+_102380156 0.254 NM_001018116
MURC
muscle-related coiled-coil protein
chr17_-_1195096 0.241 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr2_+_39000007 0.239 NM_001145451
ARHGEF33
Rho guanine nucleotide exchange factor (GEF) 33
chr3_-_120861959 0.211 NM_022135
POPDC2
popeye domain containing 2
chr4_+_187385618 0.183 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr5_-_142057692 0.177 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr3_-_15538164 0.164 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr6_+_101953389 0.160 GRIK2
glutamate receptor, ionotropic, kainate 2
chr18_+_17076166 0.160 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr4_-_26100986 0.159 NM_000730
CCKAR
cholecystokinin A receptor
chr18_+_59571256 0.155 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr11_-_117253354 0.153 NM_001164831
FXYD6
FXYD domain containing ion transport regulator 6
chr16_+_70654625 0.152 NM_020995
HPR
haptoglobin-related protein
chr4_+_114190233 0.149 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr5_+_57823017 0.149 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr11_+_14883118 0.141 CALCB
calcitonin-related polypeptide beta
chr3_-_147805715 0.141 PLSCR5
phospholipid scramblase family, member 5
chrX_+_52797004 0.140 NM_003147
NM_175698
NM_001164417
SSX2

SSX2B
synovial sarcoma, X breakpoint 2

synovial sarcoma, X breakpoint 2B
chrX_-_13745134 0.138 GPM6B
glycoprotein M6B
chr15_-_23204887 0.136 NM_000462
UBE3A
ubiquitin protein ligase E3A
chr11_+_55776251 0.133 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr6_+_25760352 0.133 NM_006998
SCGN
secretagogin, EF-hand calcium binding protein
chr16_-_11282595 0.131 NM_002761
PRM1
protamine 1
chr1_-_6502655 0.130 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chrX_+_48127911 0.130 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chrX_+_49718954 0.127 NM_000084
CLCN5
chloride channel 5
chr5_+_79651545 0.126 NM_032567
SPZ1
spermatogenic leucine zipper 1
chr19_-_56825400 0.122 NM_003830
SIGLEC5
sialic acid binding Ig-like lectin 5
chr1_+_108794426 0.120 NM_001143987
NM_001143988
NBPF4
NBPF6

neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6

chr12_-_131725848 0.120 POLE
polymerase (DNA directed), epsilon
chrX_-_15242589 0.119 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chrX_+_50670474 0.116 NM_005448
BMP15
bone morphogenetic protein 15
chr6_-_10520264 0.114 TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr10_+_129735796 0.114 NM_130435
PTPRE
protein tyrosine phosphatase, receptor type, E
chrX_-_6156655 0.113 NM_181332
NLGN4X
neuroligin 4, X-linked
chrX_-_130251068 0.113 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr17_-_33602374 0.112 NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3F
chr5_-_22248630 0.107 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr13_+_52500830 0.104 NM_006418
OLFM4
olfactomedin 4
chrX_-_130250880 0.102 IGSF1
immunoglobulin superfamily, member 1
chr10_+_114033403 0.101 NM_058222
TECTB
tectorin beta
chrX_-_106336199 0.101 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr3_-_129668780 0.100 NM_153330
DNAJB8
DnaJ (Hsp40) homolog, subfamily B, member 8
chr5_-_141318810 0.099 NM_016580
PCDH12
protocadherin 12
chrX_+_103243762 0.099 NM_001143978
ZCCHC18
zinc finger, CCHC domain containing 18
chrX_-_76823813 0.094


chr11_+_76561471 0.093 MYO7A
myosin VIIA
chrX_-_148604506 0.090 NM_001011544
MAGEA11
melanoma antigen family A, 11
chr11_+_834445 0.090 NM_001025237
TSPAN4
tetraspanin 4
chr9_-_94206648 0.089 NM_014057
NM_033014
OGN

osteoglycin

chrX_-_138742050 0.089 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr17_+_4776371 0.088 NM_000173
GP1BA
glycoprotein Ib (platelet), alpha polypeptide
chr13_-_109600709 0.088 COL4A1
collagen, type IV, alpha 1
chr19_+_54299686 0.084 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr8_+_18123456 0.083 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr12_+_10351683 0.082 NM_002262
NM_007334
KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr1_-_246804680 0.080 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr2_-_133256097 0.079 NCKAP5
NCK-associated protein 5
chr6_-_64087806 0.078 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr15_+_43331719 0.078 NM_004212
SLC28A2
solute carrier family 28 (sodium-coupled nucleoside transporter), member 2
chr16_-_46823682 0.077 NM_033151
ABCC11
ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr10_+_35934343 0.076 NM_153368
GJD4
gap junction protein, delta 4, 40.1kDa
chr6_+_101953581 0.076 NM_001166247
NM_021956
NM_175768
GRIK2


glutamate receptor, ionotropic, kainate 2


chr12_+_108035424 0.074


chr16_-_29514140 0.073


chr8_-_87824996 0.073 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr2_+_214984705 0.069 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr12_-_18134319 0.068 NM_024730
RERGL
RERG/RAS-like
chr11_-_117252541 0.067 FXYD6
FXYD domain containing ion transport regulator 6
chr3_-_58627509 0.065 NM_138805
FAM3D
family with sequence similarity 3, member D
chrX_-_52700674 0.065 NM_173358
SSX7
synovial sarcoma, X breakpoint 7
chr19_+_9064854 0.064 NM_001004456
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr11_+_19328846 0.063 NM_001111018
NAV2
neuron navigator 2
chr3_-_152585226 0.062 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr16_-_18845223 0.061 NM_015092
SMG1
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr4_-_64957595 0.057 NM_001010874
TECRL
trans-2,3-enoyl-CoA reductase-like
chr14_+_28311740 0.055 C14orf23
chromosome 14 open reading frame 23
chr1_-_12830728 0.055 NM_001146181
HNRNPCL1
LOC649330
heterogeneous nuclear ribonucleoprotein C-like 1
heterogeneous nuclear ribonucleoprotein C-like
chr8_-_93181091 0.055 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chrX_+_92815667 0.054 NM_001171109
NM_001171110
NM_001171111
NM_173698
FAM133A



family with sequence similarity 133, member A



chr10_+_83627422 0.054 NM_001165973
NRG3
neuregulin 3
chrX_-_13745108 0.046 GPM6B
glycoprotein M6B
chr9_-_139262009 0.046 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr3_+_115495522 0.045 NM_173799
TIGIT
T cell immunoreceptor with Ig and ITIM domains
chr3_-_150533948 0.045 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr6_-_10520592 0.045 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_-_155630197 0.044 NM_001038705
GPR149
G protein-coupled receptor 149
chr1_-_54861656 0.043 NM_176782
FAM151A
family with sequence similarity 151, member A
chrX_-_13745234 0.043 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr2_+_178893216 0.042 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr3_-_109730858 0.042 NM_014981
MYH15
myosin, heavy chain 15
chr12_+_97513644 0.041 SLC25A3
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
chr1_-_89230844 0.041 RBMXL1
CCBL2
RNA binding motif protein, X-linked-like 1
cysteine conjugate-beta lyase 2
chr9_-_115901157 0.041 NM_138424
KIF12
kinesin family member 12
chr1_+_246703249 0.040 NM_001005495
OR2T3
olfactory receptor, family 2, subfamily T, member 3
chr10_+_102212787 0.040 NM_003393
WNT8B
wingless-type MMTV integration site family, member 8B
chr1_+_145841569 0.038 NM_005267
GJA8
gap junction protein, alpha 8, 50kDa
chrX_+_36163971 0.037 NM_001098843
CXorf30
chromosome X open reading frame 30
chr1_+_207944807 0.037 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr11_-_57054756 0.037 NM_012456
TIMM10
translocase of inner mitochondrial membrane 10 homolog (yeast)
chr1_-_245902965 0.036 NM_001005487
OR13G1
olfactory receptor, family 13, subfamily G, member 1
chr4_-_170314382 0.036 SH3RF1
SH3 domain containing ring finger 1
chr10_-_79298876 0.036 DLG5
discs, large homolog 5 (Drosophila)
chr16_-_49742008 0.035 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr21_-_30855478 0.034 NM_181614
KRTAP19-7
keratin associated protein 19-7
chr17_-_31831093 0.033 NM_001123392
NM_032258
TBC1D3C
TBC1D3G
TBC1D3
TBC1D3H
TBC1D3F
TBC1 domain family, member 3C
TBC1 domain family, member 3G
TBC1 domain family, member 3
TBC1 domain family, member 3H
TBC1 domain family, member 3F
chr4_-_10295412 0.033 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chrX_-_48156287 0.032 NM_001034832
NM_001040612
NM_005636
NM_175729
SSX4B

SSX4

synovial sarcoma, X breakpoint 4B

synovial sarcoma, X breakpoint 4

chr5_-_58918031 0.032 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr11_-_123130435 0.030 NM_001005188
OR6X1
olfactory receptor, family 6, subfamily X, member 1
chr7_-_26198673 0.030 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr8_+_124264054 0.030 FAM83A
family with sequence similarity 83, member A
chrX_-_84250629 0.029 NM_001012980
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr1_+_148747208 0.029 ECM1
extracellular matrix protein 1
chr1_+_97033103 0.027


chr12_+_8557402 0.027 NM_080387
CLEC4D
C-type lectin domain family 4, member D
chr1_-_108588186 0.026 NM_001143989
NBPF4
NBPF6
neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6
chr6_-_28591542 0.026 NM_182701
GPX6
glutathione peroxidase 6 (olfactory)
chr22_+_24468168 0.025 MYO18B
myosin XVIIIB
chr12_-_78853365 0.024 NM_001143885
PPP1R12A
protein phosphatase 1, regulatory (inhibitor) subunit 12A
chr12_-_43555607 0.024 NM_001145109
NELL2
NEL-like 2 (chicken)
chrX_+_144716619 0.023 NM_004709
CXorf1
chromosome X open reading frame 1
chrX_-_13744933 0.022 GPM6B
glycoprotein M6B
chr3_-_14558591 0.022 NM_001080423
GRIP2
glutamate receptor interacting protein 2
chr6_-_50097606 0.021 NM_001037497
NM_001037728
DEFB110

defensin, beta 110 locus

chr9_-_16860664 0.020 BNC2
basonuclin 2
chr3_-_121117647 0.020 GSK3B
glycogen synthase kinase 3 beta
chr17_-_8602601 0.020 NM_001128076
SPDYE4
speedy homolog E4 (Xenopus laevis)
chr7_+_80105718 0.019 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr2_-_200033445 0.019 SATB2
SATB homeobox 2
chr9_+_130485754 0.017 NM_001122821
SET
SET nuclear oncogene
chr4_-_174557191 0.017 NM_007281
SCRG1
stimulator of chondrogenesis 1
chr19_+_56990222 0.016 NM_002030
FPR3
formyl peptide receptor 3
chr11_-_11331411 0.016 CSNK2A1P
casein kinase 2, alpha 1 polypeptide pseudogene
chr19_+_15713200 0.015 NM_013938
OR10H3
olfactory receptor, family 10, subfamily H, member 3
chr6_-_152681171 0.014 NM_015293
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_31117948 0.013 SDC3
syndecan 3
chr3_+_134601479 0.012 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chr15_+_63124760 0.012 NM_178859
OSTBETA
organic solute transporter beta
chr4_-_91979113 0.012 NM_183049
TMSL3
thymosin-like 3
chr5_-_142795269 0.012 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr14_-_20694023 0.011 NM_001004731
OR5AU1
olfactory receptor, family 5, subfamily AU, member 1
chr4_+_77829634 0.011 SHROOM3
shroom family member 3
chr8_-_102029997 0.011 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chrX_-_135783496 0.010


chr8_-_59575249 0.010 NM_000780
CYP7A1
cytochrome P450, family 7, subfamily A, polypeptide 1
chr3_+_122769467 0.010 NM_001012659
ARGFX
arginine-fifty homeobox
chr1_+_35623688 0.010 ZMYM4
zinc finger, MYM-type 4
chr5_-_169657312 0.010 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr11_-_49960646 0.009 NM_001005270
OR4C12
olfactory receptor, family 4, subfamily C, member 12
chr10_-_7699192 0.008 ITIH5
inter-alpha (globulin) inhibitor H5
chr11_+_117680504 0.008 NM_000733
CD3E
CD3e molecule, epsilon (CD3-TCR complex)
chr12_-_43556220 0.007 NELL2
NEL-like 2 (chicken)
chr17_+_22982372 0.006 LGALS9
lectin, galactoside-binding, soluble, 9
chr3_-_196792059 0.006 APOD
apolipoprotein D
chr21_-_30510113 0.005 NM_199328
CLDN8
claudin 8
chr7_+_80105907 0.005 CD36
CD36 molecule (thrombospondin receptor)
chr10_+_91082218 0.004 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr6_-_48186868 0.004 C6orf138
chromosome 6 open reading frame 138
chr11_+_111294810 0.004 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr17_+_55854636 0.003 NM_181707
C17orf64
chromosome 17 open reading frame 64
chr17_-_34209671 0.003 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr4_-_185963859 0.003 ACSL1
acyl-CoA synthetase long-chain family member 1
chr2_+_119416214 0.003 NM_006770
MARCO
macrophage receptor with collagenous structure
chr2_-_18634257 0.002 NM_001002006
NM_033253
NT5C1B-RDH14
NT5C1B

NT5C1B-RDH14 readthrough
5'-nucleotidase, cytosolic IB

chr1_+_148747110 0.002 NM_004425
NM_022664
ECM1

extracellular matrix protein 1

chr6_-_155818728 0.002 NM_015718
NOX3
NADPH oxidase 3
chr12_+_55201854 0.002 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_-_55790355 0.001 NM_001178079
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr12_+_119224506 0.001 NM_012240
SIRT4
sirtuin 4
chr11_+_55617328 0.000 NM_001003750
OR8I2
olfactory receptor, family 8, subfamily I, member 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.