Motif ID: ELF1,2,4.p2

Z-value: 1.662


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404543600.674.6e-03Click!
ELF4chrX_-_129072333-0.253.4e-01Click!
ELF2chr4_-_1402249140.253.5e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_+_25398690 1.714 LOC388889
hypothetical LOC388889
chr17_+_42355492 1.525 GOSR2
golgi SNAP receptor complex member 2
chr5_+_122875691 1.373 NM_001031812
NM_001044722
NM_001044723
NM_004384
 CSNK1G3



casein kinase 1, gamma 3



chr17_+_42355482 1.311 NM_001012511
NM_004287
NM_054022
 GOSR2


golgi SNAP receptor complex member 2


chr13_-_30089509 1.264 HMGB1
high-mobility group box 1
chr13_+_30089829 1.201 NM_005800
 USPL1
ubiquitin specific peptidase like 1
chr20_+_16658608 1.061 NM_003092
NM_198220
 SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr4_+_48038259 1.013 NM_020846
 SLAIN2
SLAIN motif family, member 2
chr14_+_22845851 0.937 NM_004050
 BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr6_+_36961617 0.935 NM_152734
 C6orf89
chromosome 6 open reading frame 89
chr5_+_162865128 0.912 NM_013283
 MAT2B
methionine adenosyltransferase II, beta
chr17_+_4784524 0.894 RNF167
ring finger protein 167
chr20_+_33750645 0.867 NM_080748
 ROMO1
reactive oxygen species modulator 1
chr12_+_51686328 0.854 NM_001417
 EIF4B
eukaryotic translation initiation factor 4B
chr20_-_33750457 0.842 NM_001198989
NM_021100
 NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr10_-_51293220 0.834 NM_006327
 TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr15_+_91248706 0.821 CHD2
chromodomain helicase DNA binding protein 2
chr4_+_48038095 0.812 SLAIN2
SLAIN motif family, member 2
chr1_+_118273869 0.806 WDR3
WD repeat domain 3
chr20_+_29598848 0.795 HM13
histocompatibility (minor) 13

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 116 entries
enrichment   p-value GO term description
2.10 2.52e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
2.09 1.21e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.09 1.21e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.09 1.21e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.09 1.21e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.09 1.21e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.09 1.21e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.09 1.21e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.09 1.21e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
2.07 5.34e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.06 2.21e-04 GO:0030330 DNA damage response, signal transduction by p53 class mediator
2.05 1.48e-02 GO:0071158 positive regulation of cell cycle arrest
2.03 1.65e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
2.01 1.02e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
2.00 4.45e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.98 3.94e-03 GO:0051351 positive regulation of ligase activity
1.98 6.85e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.98 6.85e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
1.98 6.85e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.98 6.85e-03 GO:0071779 G1/S transition checkpoint

Gene overrepresentation in compartment category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
2.36 2.43e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.96 1.47e-02 GO:0000502 proteasome complex
1.91 1.18e-03 GO:0001726 ruffle
1.86 2.17e-05 GO:0005681 spliceosomal complex
1.81 3.49e-02 GO:0031461 cullin-RING ubiquitin ligase complex
1.81 3.49e-02 GO:0071013 catalytic step 2 spliceosome
1.80 6.69e-05 GO:0000151 ubiquitin ligase complex
1.72 2.90e-05 GO:0031252 cell leading edge
1.59 4.59e-11 GO:0030529 ribonucleoprotein complex
1.56 8.66e-03 GO:0005840 ribosome
1.42 6.45e-05 GO:0005730 nucleolus
1.40 1.45e-02 GO:0005815 microtubule organizing center
1.33 1.53e-18 GO:0031974 membrane-enclosed lumen
1.33 2.12e-18 GO:0043233 organelle lumen
1.33 4.57e-18 GO:0070013 intracellular organelle lumen
1.33 2.35e-13 GO:0031981 nuclear lumen
1.32 2.56e-15 GO:0044428 nuclear part
1.31 1.36e-13 GO:0005829 cytosol
1.31 2.58e-08 GO:0005654 nucleoplasm
1.23 6.38e-04 GO:0005739 mitochondrion

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.17 9.86e-03 GO:0003743 translation initiation factor activity
2.05 2.14e-04 GO:0008135 translation factor activity, nucleic acid binding
1.49 9.78e-13 GO:0003723 RNA binding
1.28 7.18e-03 GO:0019899 enzyme binding
1.21 6.22e-11 GO:0003676 nucleic acid binding
1.16 1.06e-20 GO:0005515 protein binding
1.14 3.13e-02 GO:0000166 nucleotide binding
1.07 2.93e-13 GO:0005488 binding