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• Mean activities

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• Activity deltas table
• Regulatory interactions
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Motif ID: ELF1,2,4.p2

Z-value: 1.662

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_+_25398690	1.714		LOC388889	hypothetical LOC388889
chr17_+_42355492	1.525		GOSR2	golgi SNAP receptor complex member 2
chr5_+_122875691	1.373	NM_001031812 NM_001044722 NM_001044723 NM_004384	CSNK1G3	casein kinase 1, gamma 3
chr17_+_42355482	1.311	NM_001012511 NM_004287 NM_054022	GOSR2	golgi SNAP receptor complex member 2
chr13_-_30089509	1.264		HMGB1	high-mobility group box 1
chr13_+_30089829	1.201	NM_005800	USPL1	ubiquitin specific peptidase like 1
chr20_+_16658608	1.061	NM_003092 NM_198220	SNRPB2	small nuclear ribonucleoprotein polypeptide B
chr4_+_48038259	1.013	NM_020846	SLAIN2	SLAIN motif family, member 2
chr14_+_22845851	0.937	NM_004050	BCL2L2-PABPN1 BCL2L2	BCL2L2-PABPN1 read-through transcript BCL2-like 2
chr6_+_36961617	0.935	NM_152734	C6orf89	chromosome 6 open reading frame 89
chr5_+_162865128	0.912	NM_013283	MAT2B	methionine adenosyltransferase II, beta
chr17_+_4784524	0.894		RNF167	ring finger protein 167
chr20_+_33750645	0.867	NM_080748	ROMO1	reactive oxygen species modulator 1
chr12_+_51686328	0.854	NM_001417	EIF4B	eukaryotic translation initiation factor 4B
chr20_-_33750457	0.842	NM_001198989 NM_021100	NFS1	NFS1 nitrogen fixation 1 homolog (S. cerevisiae)
chr10_-_51293220	0.834	NM_006327	TIMM23 TIMM23B	translocase of inner mitochondrial membrane 23 homolog (yeast) translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr15_+_91248706	0.821		CHD2	chromodomain helicase DNA binding protein 2
chr4_+_48038095	0.812		SLAIN2	SLAIN motif family, member 2
chr1_+_118273869	0.806		WDR3	WD repeat domain 3
chr20_+_29598848	0.795		HM13	histocompatibility (minor) 13
chr16_+_2593351	0.787		LOC652276	hypothetical LOC652276
chr1_-_118273701	0.772		GDAP2	ganglioside induced differentiation associated protein 2
chr2_-_53867488	0.768	NM_016115 NM_145863	ASB3	ankyrin repeat and SOCS box containing 3
chr7_+_27746335	0.762		TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1
chr9_+_132579088	0.760	NM_007313	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr10_-_51041156	0.759	NM_003631	AGAP8 LOC728407 PARG	ArfGAP with GTPase domain, ankyrin repeat and PH domain 8 poly(ADP-ribose) glycohydrolase pseudogene poly (ADP-ribose) glycohydrolase
chr2_+_27659396	0.756	NM_032434	ZNF512	zinc finger protein 512
chr3_+_30623376	0.735		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr14_+_62740878	0.730	NM_020663	RHOJ	ras homolog gene family, member J
chr7_+_27746334	0.729
chr7_+_99451110	0.696	NM_003439	ZKSCAN1	zinc finger with KRAB and SCAN domains 1
chr9_+_130354490	0.687	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chr1_+_118273887	0.683	NM_006784	WDR3	WD repeat domain 3
chr15_-_75693309	0.679		LINGO1	leucine rich repeat and Ig domain containing 1
chr18_+_3252184	0.679		MYL12B	myosin, light chain 12B, regulatory
chr12_+_51686504	0.677		EIF4B	eukaryotic translation initiation factor 4B
chr2_+_210575600	0.671	NM_199229	RPE	ribulose-5-phosphate-3-epimerase
chr16_+_74239135	0.667	NM_018975	TERF2IP	telomeric repeat binding factor 2, interacting protein
chr2_+_210575566	0.662	NM_006916	RPE	ribulose-5-phosphate-3-epimerase
chr18_+_3252110	0.656	NM_033546	MYL12B	myosin, light chain 12B, regulatory
chr20_+_34635362	0.652	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr22_+_45537181	0.650	NM_014346	TBC1D22A	TBC1 domain family, member 22A
chr19_+_16157198	0.647	NM_014077	FAM32A	family with sequence similarity 32, member A
chr3_+_57517013	0.644	NM_177966	PDE12	phosphodiesterase 12
chr7_+_27746268	0.639		TAX1BP1	Tax1 (human T-cell leukemia virus type I) binding protein 1
chr17_+_70520339	0.632	NM_001545	ICT1	immature colon carcinoma transcript 1
chr15_+_81216349	0.629
chr14_+_68935133	0.628	NM_018375	SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr15_-_81216179	0.627
chr6_+_169844186	0.627		C6orf120	chromosome 6 open reading frame 120
chr14_+_73423260	0.626	NM_021188	ZNF410	zinc finger protein 410
chr14_+_68935172	0.623		SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr6_+_169844213	0.620		C6orf120	chromosome 6 open reading frame 120
chr14_+_38720085	0.620		PNN	pinin, desmosome associated protein
chr15_+_75500284	0.618	NM_018200	HMG20A	high-mobility group 20A
chr12_+_51686512	0.617		EIF4B	eukaryotic translation initiation factor 4B
chr15_+_36331411	0.615		SPRED1	sprouty-related, EVH1 domain containing 1
chr6_+_169844161	0.609	NM_001029863	C6orf120	chromosome 6 open reading frame 120
chr2_+_218790109	0.598	NM_152862	ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr5_+_69732561	0.597		SMA4	glucuronidase, beta pseudogene
chr4_+_109761170	0.592	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr4_+_57028536	0.592		SRP72	signal recognition particle 72kDa
chr2_+_198278276	0.585	NM_138395	MARS2	methionyl-tRNA synthetase 2, mitochondrial
chr9_+_128607081	0.584	NM_001135776 NM_014007	ZBTB43	zinc finger and BTB domain containing 43
chr16_-_74239030	0.583	NM_001130089 NM_005548	KARS	lysyl-tRNA synthetase
chr3_+_57517094	0.582		PDE12	phosphodiesterase 12
chr9_+_99435900	0.582		NCBP1	nuclear cap binding protein subunit 1, 80kDa
chr16_+_8799170	0.581	NM_000303	PMM2	phosphomannomutase 2
chr7_+_39629782	0.581		RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr6_+_133177403	0.575		RPS12	ribosomal protein S12
chr2_+_218790143	0.570		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr20_-_34635091	0.570
chr13_+_44937025	0.570	NM_031431	COG3	component of oligomeric golgi complex 3
chr13_+_41744255	0.567	NM_016248	AKAP11	A kinase (PRKA) anchor protein 11
chr6_+_3966499	0.562	NM_003913	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr6_+_147567200	0.561	NM_001127715 NM_139244	STXBP5	syntaxin binding protein 5 (tomosyn)
chr15_+_66357456	0.549		FEM1B	fem-1 homolog b (C. elegans)
chr8_+_11179724	0.549		MTMR9	myotubularin related protein 9
chr17_+_64019748	0.545		PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr16_+_24648446	0.545	NM_014494	TNRC6A	trinucleotide repeat containing 6A
chr1_+_24842381	0.544		SRRM1	serine/arginine repetitive matrix 1
chr6_+_169844128	0.539		C6orf120	chromosome 6 open reading frame 120
chr16_-_8798973	0.538	NM_015421	TMEM186	transmembrane protein 186
chr14_-_77244073	0.538	NM_006020	ALKBH1	alkB, alkylation repair homolog 1 (E. coli)
chr14_-_49157076	0.534	NM_001001	RPL36AL	ribosomal protein L36a-like
chr4_-_153920326	0.533	NM_145720	TIGD4	tigger transposable element derived 4
chr2_+_176842368	0.530	NM_006554	MTX2	metaxin 2
chr14_+_22634585	0.529		C14orf119	chromosome 14 open reading frame 119
chr20_+_46971618	0.527	NM_006420	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_-_72111027	0.527	NM_001135190 NM_015242	ARAP1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_+_178685396	0.527	NM_152945	RBM45	RNA binding motif protein 45
chr7_+_39629724	0.523		RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr16_-_23476138	0.521	NM_001083614	EARS2	glutamyl-tRNA synthetase 2, mitochondrial (putative)
chr14_+_22634517	0.521		C14orf119	chromosome 14 open reading frame 119
chr2_+_69974581	0.517	NM_006857	SNRNP27	small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr3_+_185515543	0.515	NM_182917	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr2_-_196641682	0.514	NM_018897	DNAH7	dynein, axonemal, heavy chain 7
chr2_+_218790159	0.512		ARPC2	actin related protein 2/3 complex, subunit 2, 34kDa
chr13_+_76464044	0.512	NM_006493	CLN5	ceroid-lipofuscinosis, neuronal 5
chr15_+_65145248	0.511	NM_005902	SMAD3	SMAD family member 3
chr2_+_32435800	0.510		BIRC6	baculoviral IAP repeat containing 6
chr11_+_63363174	0.508		MARK2	MAP/microtubule affinity-regulating kinase 2
chr6_-_11490487	0.506	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr14_+_34831294	0.504	NM_002791	PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_34831355	0.504		PSMA6	proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_68934855	0.504		SLC39A9	solute carrier family 39 (zinc transporter), member 9
chr9_-_132444639	0.504		LOC100272217	hypothetical LOC100272217
chr2_+_65308332	0.503	NM_001005386 NM_005722	ACTR2	ARP2 actin-related protein 2 homolog (yeast)
chr3_+_133861894	0.503		UBA5	ubiquitin-like modifier activating enzyme 5
chr19_+_50150486	0.503		CLPTM1	cleft lip and palate associated transmembrane protein 1
chr14_+_77244177	0.501	NM_031210	C14orf156	chromosome 14 open reading frame 156
chr4_+_153920563	0.501		ARFIP1	ADP-ribosylation factor interacting protein 1
chr17_-_71174816	0.501	NM_004259 NM_001003715 NM_001003716	RECQL5	RecQ protein-like 5
chr6_-_169844023	0.497	NM_182552	WDR27	WD repeat domain 27
chr14_+_22634621	0.496	NM_017924	C14orf119	chromosome 14 open reading frame 119
chr1_-_118273728	0.496	NM_001135589 NM_017686	GDAP2	ganglioside induced differentiation associated protein 2
chr8_+_125620523	0.494	NM_005005	NDUFB9	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr4_+_56414565	0.492	NM_001024924 NM_018261 NM_178237	EXOC1	exocyst complex component 1
chr8_+_117847945	0.491		UTP23	UTP23, small subunit (SSU) processome component, homolog (yeast)
chr19_+_50150441	0.491	NM_001294	CLPTM1	cleft lip and palate associated transmembrane protein 1
chr1_+_109892741	0.490		GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr7_+_39629665	0.490	NM_005402	RALA	v-ral simian leukemia viral oncogene homolog A (ras related)
chr14_+_96038479	0.483		PAPOLA	poly(A) polymerase alpha
chr8_+_117847922	0.482	NM_032334	UTP23	UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_-_22634662	0.482	NM_001164814 NM_001164815 NM_014977	ACIN1	apoptotic chromatin condensation inducer 1
chr17_-_24013303	0.481		SDF2	stromal cell-derived factor 2
chr16_+_79626817	0.481	NM_015251	ATMIN	ATM interactor
chr14_+_54104099	0.480		SAMD4A	sterile alpha motif domain containing 4A
chr3_+_61522219	0.480	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr12_-_61283474	0.477	NM_175895	C12orf61	chromosome 12 open reading frame 61
chr17_+_24013359	0.476	NM_003170	SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)
chr4_+_153920382	0.474	NM_001025593 NM_001025595 NM_014447	ARFIP1	ADP-ribosylation factor interacting protein 1
chr22_-_45537081	0.473
chr16_+_48865521	0.472		ADCY7	adenylate cyclase 7
chr15_+_56850776	0.471		FAM63B	family with sequence similarity 63, member B
chr11_+_74950893	0.471		SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr20_+_3138055	0.470	NM_033453 NM_181493	ITPA	inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
chr12_-_99184883	0.470	NM_152317	DEPDC4	DEP domain containing 4
chr20_+_43028533	0.469	NM_006282	STK4	serine/threonine kinase 4
chr2_+_239000395	0.469		ASB1	ankyrin repeat and SOCS box containing 1
chr14_+_77244191	0.469		C14orf156	chromosome 14 open reading frame 156
chr1_+_109892760	0.468		GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_+_65658903	0.466	NM_001003679 NM_001003680 NM_002303 NM_001198681	LEPR LEPROT	leptin receptor leptin receptor overlapping transcript
chr16_+_23476334	0.466	NM_019116	UBFD1	ubiquitin family domain containing 1
chr14_+_101346032	0.466		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr2_+_53867571	0.465	NM_001127397 NM_001127398 NM_015701	ERLEC1	endoplasmic reticulum lectin 1
chr5_+_67620007	0.464	NM_181524	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_43212703	0.462	NM_001098207	HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr2_+_198089036	0.458		MOBKL3	MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr15_+_88610181	0.457		NGRN	neugrin, neurite outgrowth associated
chr11_-_65860450	0.457	NM_004292	RIN1	Ras and Rab interactor 1
chr11_+_63362922	0.456	NM_001039469 NM_001163296 NM_001163297 NM_004954	MARK2	MAP/microtubule affinity-regulating kinase 2
chr17_+_24013320	0.455		SUPT6H	suppressor of Ty 6 homolog (S. cerevisiae)
chr17_+_55052185	0.451
chr16_+_72888231	0.451		PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_+_144325533	0.450		USP38	ubiquitin specific peptidase 38
chr6_+_26646548	0.450	NM_006353	HMGN4	high mobility group nucleosomal binding domain 4
chr3_+_180348818	0.449	NM_006218	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr17_+_59205289	0.449	NM_007372 NM_203499	DDX42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr16_+_72888161	0.448	NM_002811	PSMD7	proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_+_144325502	0.446	NM_032557	USP38	ubiquitin specific peptidase 38
chr12_+_99184977	0.446		SCYL2	SCY1-like 2 (S. cerevisiae)
chr20_+_43028590	0.443		STK4	serine/threonine kinase 4
chr1_+_94656517	0.442	NM_001122674 NM_002858	ABCD3	ATP-binding cassette, sub-family D (ALD), member 3
chr9_+_4669557	0.442	NM_017913	CDC37L1	cell division cycle 37 homolog (S. cerevisiae)-like 1
chr3_+_144203061	0.441	NM_001080415	U2SURP	U2 snRNP-associated SURP domain containing
chr2_+_64605049	0.440		AFTPH	aftiphilin
chr17_+_55139644	0.440	NM_030938	VMP1	vacuole membrane protein 1
chr8_-_125620466	0.440	NM_001146160 NM_032026	TATDN1	TatD DNase domain containing 1
chr14_+_52243645	0.440	NM_002806	PSMC6	proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr12_+_99185289	0.439		SCYL2	SCY1-like 2 (S. cerevisiae)
chr21_+_44256630	0.439	NM_003274	TRAPPC10	trafficking protein particle complex 10
chr2_+_118288754	0.439		DDX18	DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_+_161725172	0.437		TANK	TRAF family member-associated NFKB activator
chr17_+_33761234	0.435	NM_014598	SOCS7	suppressor of cytokine signaling 7
chr12_-_52868855	0.434	NM_014311	SMUG1	single-strand-selective monofunctional uracil-DNA glycosylase 1
chr14_+_101345878	0.432	NM_002719 NM_178586 NM_178587	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr15_+_56850681	0.432	NM_001040450 NM_001040453	FAM63B	family with sequence similarity 63, member B
chr14_-_22634134	0.432		ACIN1	apoptotic chromatin condensation inducer 1
chr3_+_140545528	0.430	NM_020191	MRPS22	mitochondrial ribosomal protein S22
chr2_+_182464713	0.429	NM_001130445 NM_006751	SSFA2	sperm specific antigen 2
chr17_-_24013259	0.429		SDF2	stromal cell-derived factor 2
chr20_-_48741481	0.429
chr5_+_61910318	0.428	NM_181506	LRRC70	leucine rich repeat containing 70
chr17_+_55139743	0.428		VMP1	vacuole membrane protein 1
chr4_+_57028503	0.427	NM_006947	SRP72	signal recognition particle 72kDa
chr3_+_61522310	0.427		PTPRG	protein tyrosine phosphatase, receptor type, G
chr17_+_59205244	0.426
chr2_-_201461945	0.426	NM_032472 NM_130906	PPIL3	peptidylprolyl isomerase (cyclophilin)-like 3
chr17_+_55139792	0.424		VMP1	vacuole membrane protein 1
chr5_+_72830029	0.423		BTF3	basic transcription factor 3
chr15_+_88609837	0.423	NM_001033088	NGRN	neugrin, neurite outgrowth associated
chr10_+_18988282	0.423	NM_178815	ARL5B	ADP-ribosylation factor-like 5B
chr1_+_65658718	0.422	NM_001198683 NM_017526	LEPROT	leptin receptor overlapping transcript
chr10_-_43212681	0.419		HNRNPF	heterogeneous nuclear ribonucleoprotein F
chr5_+_72830003	0.417	NM_001037637 NM_001207	BTF3	basic transcription factor 3
chr4_+_119825983	0.417	NM_020961	METTL14	methyltransferase like 14
chr1_+_94656556	0.415		ABCD3	ATP-binding cassette, sub-family D (ALD), member 3
chr17_+_64019693	0.414	NM_212471	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr17_+_55139793	0.413		VMP1	vacuole membrane protein 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.26	7.37e-24	GO:0044260	cellular macromolecule metabolic process
1.21	2.24e-18	GO:0043170	macromolecule metabolic process
1.17	3.03e-17	GO:0044237	cellular metabolic process
1.29	5.12e-16	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31	2.03e-13	GO:0090304	nucleic acid metabolic process
1.34	3.96e-13	GO:0010467	gene expression
1.15	1.10e-12	GO:0044238	primary metabolic process
1.27	2.91e-12	GO:0044267	cellular protein metabolic process
1.34	6.79e-12	GO:0016070	RNA metabolic process
1.13	9.09e-12	GO:0008152	metabolic process
1.32	1.20e-10	GO:0009059	macromolecule biosynthetic process
1.22	3.74e-10	GO:0034641	cellular nitrogen compound metabolic process
1.59	3.82e-10	GO:0016071	mRNA metabolic process
1.32	3.94e-10	GO:0034645	cellular macromolecule biosynthetic process
1.08	6.96e-10	GO:0009987	cellular process
1.21	1.85e-09	GO:0006807	nitrogen compound metabolic process
1.57	2.61e-09	GO:0044265	cellular macromolecule catabolic process
1.50	8.12e-09	GO:0006396	RNA processing
1.72	1.01e-08	GO:0006511	ubiquitin-dependent protein catabolic process
1.70	1.22e-08	GO:0070647	protein modification by small protein conjugation or removal
1.22	1.35e-08	GO:0071841	cellular component organization or biogenesis at cellular level
1.19	1.40e-08	GO:0071840	cellular component organization or biogenesis
1.67	1.45e-08	GO:0030163	protein catabolic process
1.51	1.87e-08	GO:0009057	macromolecule catabolic process
1.38	2.14e-08	GO:0007049	cell cycle
1.68	4.69e-08	GO:0051603	proteolysis involved in cellular protein catabolic process
1.68	4.88e-08	GO:0044257	cellular protein catabolic process
1.69	5.81e-08	GO:0019941	modification-dependent protein catabolic process
1.68	1.02e-07	GO:0043632	modification-dependent macromolecule catabolic process
1.43	1.18e-07	GO:0046907	intracellular transport
1.42	1.54e-07	GO:0022402	cell cycle process
1.19	1.66e-07	GO:0016043	cellular component organization
1.20	1.69e-07	GO:0019538	protein metabolic process
1.28	2.09e-07	GO:0006996	organelle organization
1.68	2.12e-07	GO:0006412	translation
1.49	2.38e-07	GO:0000278	mitotic cell cycle
1.71	2.89e-07	GO:0032446	protein modification by small protein conjugation
1.21	3.01e-07	GO:0071842	cellular component organization at cellular level
1.34	3.73e-07	GO:0044248	cellular catabolic process
1.59	5.36e-07	GO:0006397	mRNA processing
1.73	5.52e-07	GO:0016567	protein ubiquitination
1.43	1.29e-06	GO:0022403	cell cycle phase
1.21	4.32e-06	GO:0044249	cellular biosynthetic process
1.88	4.85e-06	GO:0010498	proteasomal protein catabolic process
1.88	4.85e-06	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
1.54	5.06e-06	GO:0016032	viral reproduction
1.20	8.76e-06	GO:0009058	biosynthetic process
1.31	2.95e-05	GO:0051649	establishment of localization in cell
1.28	5.80e-05	GO:0051641	cellular localization
1.40	1.12e-04	GO:0051726	regulation of cell cycle
1.71	1.23e-04	GO:0000375	RNA splicing, via transesterification reactions
1.34	1.38e-04	GO:0015031	protein transport
1.57	1.49e-04	GO:0051325	interphase
1.33	1.50e-04	GO:0045184	establishment of protein localization
1.71	1.55e-04	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.71	1.55e-04	GO:0000398	nuclear mRNA splicing, via spliceosome
1.36	1.60e-04	GO:0016192	vesicle-mediated transport
1.57	1.91e-04	GO:0008380	RNA splicing
1.26	1.93e-04	GO:0033036	macromolecule localization
2.06	2.21e-04	GO:0030330	DNA damage response, signal transduction by p53 class mediator
1.15	2.68e-04	GO:0060255	regulation of macromolecule metabolic process
1.25	2.81e-04	GO:0009056	catabolic process
1.30	3.28e-04	GO:0032268	regulation of cellular protein metabolic process
1.93	3.29e-04	GO:0031398	positive regulation of protein ubiquitination
1.33	3.51e-04	GO:0033554	cellular response to stress
1.55	3.80e-04	GO:0051329	interphase of mitotic cell cycle
1.42	4.70e-04	GO:0006974	response to DNA damage stimulus
1.56	1.05e-03	GO:0010608	posttranscriptional regulation of gene expression
1.27	1.35e-03	GO:0008104	protein localization
2.03	1.65e-03	GO:0031145	anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.27	2.21e-03	GO:0051246	regulation of protein metabolic process
2.10	2.52e-03	GO:0031571	mitotic cell cycle G1/S transition DNA damage checkpoint
1.75	2.72e-03	GO:0000082	G1/S transition of mitotic cell cycle
1.57	2.96e-03	GO:0032269	negative regulation of cellular protein metabolic process
1.98	3.94e-03	GO:0051351	positive regulation of ligase activity
2.00	4.45e-03	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.84	4.93e-03	GO:0042770	signal transduction in response to DNA damage
1.82	5.32e-03	GO:0051320	S phase
2.07	5.34e-03	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.89	6.48e-03	GO:0051340	regulation of ligase activity
1.98	6.85e-03	GO:0000216	M/G1 transition of mitotic cell cycle
1.98	6.85e-03	GO:0031575	mitotic cell cycle G1/S transition checkpoint
1.98	6.85e-03	GO:0051443	positive regulation of ubiquitin-protein ligase activity
1.98	6.85e-03	GO:0071779	G1/S transition checkpoint
1.43	7.20e-03	GO:0006886	intracellular protein transport
1.82	9.18e-03	GO:0000077	DNA damage checkpoint
1.19	9.95e-03	GO:0006464	protein modification process
2.01	1.02e-02	GO:0051437	positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.89	1.12e-02	GO:0051438	regulation of ubiquitin-protein ligase activity
1.70	1.17e-02	GO:0031396	regulation of protein ubiquitination
1.93	1.18e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
2.09	1.21e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.09	1.21e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
2.09	1.21e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
2.09	1.21e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
2.09	1.21e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
2.09	1.21e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
2.09	1.21e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.09	1.21e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
1.36	1.27e-02	GO:0070727	cellular macromolecule localization
1.36	1.33e-02	GO:0034613	cellular protein localization
1.52	1.37e-02	GO:0051248	negative regulation of protein metabolic process
2.05	1.48e-02	GO:0071158	positive regulation of cell cycle arrest
1.79	1.80e-02	GO:0000084	S phase of mitotic cell cycle
1.98	2.07e-02	GO:0051352	negative regulation of ligase activity
1.98	2.07e-02	GO:0051444	negative regulation of ubiquitin-protein ligase activity
1.64	2.19e-02	GO:0006417	regulation of translation
1.08	2.41e-02	GO:0050794	regulation of cellular process
1.27	2.78e-02	GO:0016265	death
1.12	2.99e-02	GO:0031323	regulation of cellular metabolic process
1.46	3.04e-02	GO:0031401	positive regulation of protein modification process
1.74	3.58e-02	GO:0031570	DNA integrity checkpoint
1.26	3.76e-02	GO:0008219	cell death
1.45	3.76e-02	GO:0048285	organelle fission
1.42	4.18e-02	GO:0010564	regulation of cell cycle process
1.55	4.21e-02	GO:0071843	cellular component biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.13	1.74e-38	GO:0044424	intracellular part
1.12	1.47e-37	GO:0005622	intracellular
1.15	7.05e-34	GO:0043229	intracellular organelle
1.15	7.26e-34	GO:0043226	organelle
1.16	1.93e-31	GO:0043231	intracellular membrane-bounded organelle
1.16	2.23e-31	GO:0043227	membrane-bounded organelle
1.21	2.21e-23	GO:0005634	nucleus
1.33	1.53e-18	GO:0031974	membrane-enclosed lumen
1.33	2.12e-18	GO:0043233	organelle lumen
1.33	4.57e-18	GO:0070013	intracellular organelle lumen
1.13	1.64e-17	GO:0005737	cytoplasm
1.18	6.17e-17	GO:0044446	intracellular organelle part
1.17	5.26e-16	GO:0044422	organelle part
1.16	1.60e-15	GO:0044444	cytoplasmic part
1.32	2.56e-15	GO:0044428	nuclear part
1.31	1.36e-13	GO:0005829	cytosol
1.33	2.35e-13	GO:0031981	nuclear lumen
1.59	4.59e-11	GO:0030529	ribonucleoprotein complex
1.19	3.76e-10	GO:0032991	macromolecular complex
1.31	2.58e-08	GO:0005654	nucleoplasm
1.20	4.65e-08	GO:0043228	non-membrane-bounded organelle
1.20	4.65e-08	GO:0043232	intracellular non-membrane-bounded organelle
1.86	2.17e-05	GO:0005681	spliceosomal complex
1.03	2.73e-05	GO:0044464	cell part
1.72	2.90e-05	GO:0031252	cell leading edge
1.03	2.93e-05	GO:0005623	cell
1.42	6.45e-05	GO:0005730	nucleolus
1.80	6.69e-05	GO:0000151	ubiquitin ligase complex
1.15	2.10e-04	GO:0043234	protein complex
1.23	6.38e-04	GO:0005739	mitochondrion
1.91	1.18e-03	GO:0001726	ruffle
1.56	8.66e-03	GO:0005840	ribosome
1.40	1.45e-02	GO:0005815	microtubule organizing center
1.96	1.47e-02	GO:0000502	proteasome complex
2.36	2.43e-02	GO:0030532	small nuclear ribonucleoprotein complex
1.81	3.49e-02	GO:0031461	cullin-RING ubiquitin ligase complex
1.81	3.49e-02	GO:0071013	catalytic step 2 spliceosome

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.16	1.06e-20	GO:0005515	protein binding
1.07	2.93e-13	GO:0005488	binding
1.49	9.78e-13	GO:0003723	RNA binding
1.21	6.22e-11	GO:0003676	nucleic acid binding
2.05	2.14e-04	GO:0008135	translation factor activity, nucleic acid binding
1.28	7.18e-03	GO:0019899	enzyme binding
2.17	9.86e-03	GO:0003743	translation initiation factor activity
1.14	3.13e-02	GO:0000166	nucleotide binding