Motif ID: ELF1,2,4.p2

Z-value: 1.662


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF1chr13_-_404543600.674.6e-03Click!
ELF4chrX_-_129072333-0.253.4e-01Click!
ELF2chr4_-_1402249140.253.5e-01Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_25398690 1.714 LOC388889
hypothetical LOC388889
chr17_+_42355492 1.525 GOSR2
golgi SNAP receptor complex member 2
chr5_+_122875691 1.373 NM_001031812
NM_001044722
NM_001044723
NM_004384
CSNK1G3



casein kinase 1, gamma 3



chr17_+_42355482 1.311 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr13_-_30089509 1.264 HMGB1
high-mobility group box 1
chr13_+_30089829 1.201 NM_005800
USPL1
ubiquitin specific peptidase like 1
chr20_+_16658608 1.061 NM_003092
NM_198220
SNRPB2

small nuclear ribonucleoprotein polypeptide B

chr4_+_48038259 1.013 NM_020846
SLAIN2
SLAIN motif family, member 2
chr14_+_22845851 0.937 NM_004050
BCL2L2-PABPN1
BCL2L2
BCL2L2-PABPN1 read-through transcript
BCL2-like 2
chr6_+_36961617 0.935 NM_152734
C6orf89
chromosome 6 open reading frame 89
chr5_+_162865128 0.912 NM_013283
MAT2B
methionine adenosyltransferase II, beta
chr17_+_4784524 0.894 RNF167
ring finger protein 167
chr20_+_33750645 0.867 NM_080748
ROMO1
reactive oxygen species modulator 1
chr12_+_51686328 0.854 NM_001417
EIF4B
eukaryotic translation initiation factor 4B
chr20_-_33750457 0.842 NM_001198989
NM_021100
NFS1

NFS1 nitrogen fixation 1 homolog (S. cerevisiae)

chr10_-_51293220 0.834 NM_006327
TIMM23
TIMM23B
translocase of inner mitochondrial membrane 23 homolog (yeast)
translocase of inner mitochondrial membrane 23 homolog B (yeast)
chr15_+_91248706 0.821 CHD2
chromodomain helicase DNA binding protein 2
chr4_+_48038095 0.812 SLAIN2
SLAIN motif family, member 2
chr1_+_118273869 0.806 WDR3
WD repeat domain 3
chr20_+_29598848 0.795 HM13
histocompatibility (minor) 13
chr16_+_2593351 0.787 LOC652276
hypothetical LOC652276
chr1_-_118273701 0.772 GDAP2
ganglioside induced differentiation associated protein 2
chr2_-_53867488 0.768 NM_016115
NM_145863
ASB3

ankyrin repeat and SOCS box containing 3

chr7_+_27746335 0.762 TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr9_+_132579088 0.760 NM_007313
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr10_-_51041156 0.759 NM_003631
AGAP8
LOC728407
PARG
ArfGAP with GTPase domain, ankyrin repeat and PH domain 8
poly(ADP-ribose) glycohydrolase pseudogene
poly (ADP-ribose) glycohydrolase
chr2_+_27659396 0.756 NM_032434
ZNF512
zinc finger protein 512
chr3_+_30623376 0.735 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_62740878 0.730 NM_020663
RHOJ
ras homolog gene family, member J
chr7_+_27746334 0.729


chr7_+_99451110 0.696 NM_003439
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr9_+_130354490 0.687 NM_001130438
NM_001195532
NM_003127
SPTAN1


spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)


chr1_+_118273887 0.683 NM_006784
WDR3
WD repeat domain 3
chr15_-_75693309 0.679 LINGO1
leucine rich repeat and Ig domain containing 1
chr18_+_3252184 0.679 MYL12B
myosin, light chain 12B, regulatory
chr12_+_51686504 0.677 EIF4B
eukaryotic translation initiation factor 4B
chr2_+_210575600 0.671 NM_199229
RPE
ribulose-5-phosphate-3-epimerase
chr16_+_74239135 0.667 NM_018975
TERF2IP
telomeric repeat binding factor 2, interacting protein
chr2_+_210575566 0.662 NM_006916
RPE
ribulose-5-phosphate-3-epimerase
chr18_+_3252110 0.656 NM_033546
MYL12B
myosin, light chain 12B, regulatory
chr20_+_34635362 0.652 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr22_+_45537181 0.650 NM_014346
TBC1D22A
TBC1 domain family, member 22A
chr19_+_16157198 0.647 NM_014077
FAM32A
family with sequence similarity 32, member A
chr3_+_57517013 0.644 NM_177966
PDE12
phosphodiesterase 12
chr7_+_27746268 0.639 TAX1BP1
Tax1 (human T-cell leukemia virus type I) binding protein 1
chr17_+_70520339 0.632 NM_001545
ICT1
immature colon carcinoma transcript 1
chr15_+_81216349 0.629


chr14_+_68935133 0.628 NM_018375
SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr15_-_81216179 0.627


chr6_+_169844186 0.627 C6orf120
chromosome 6 open reading frame 120
chr14_+_73423260 0.626 NM_021188
ZNF410
zinc finger protein 410
chr14_+_68935172 0.623 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr6_+_169844213 0.620 C6orf120
chromosome 6 open reading frame 120
chr14_+_38720085 0.620 PNN
pinin, desmosome associated protein
chr15_+_75500284 0.618 NM_018200
HMG20A
high-mobility group 20A
chr12_+_51686512 0.617 EIF4B
eukaryotic translation initiation factor 4B
chr15_+_36331411 0.615 SPRED1
sprouty-related, EVH1 domain containing 1
chr6_+_169844161 0.609 NM_001029863
C6orf120
chromosome 6 open reading frame 120
chr2_+_218790109 0.598 NM_152862
ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr5_+_69732561 0.597 SMA4
glucuronidase, beta pseudogene
chr4_+_109761170 0.592 NM_000995
NM_033625
RPL34

ribosomal protein L34

chr4_+_57028536 0.592 SRP72
signal recognition particle 72kDa
chr2_+_198278276 0.585 NM_138395
MARS2
methionyl-tRNA synthetase 2, mitochondrial
chr9_+_128607081 0.584 NM_001135776
NM_014007
ZBTB43

zinc finger and BTB domain containing 43

chr16_-_74239030 0.583 NM_001130089
NM_005548
KARS

lysyl-tRNA synthetase

chr3_+_57517094 0.582 PDE12
phosphodiesterase 12
chr9_+_99435900 0.582 NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr16_+_8799170 0.581 NM_000303
PMM2
phosphomannomutase 2
chr7_+_39629782 0.581 RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr6_+_133177403 0.575 RPS12
ribosomal protein S12
chr2_+_218790143 0.570 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr20_-_34635091 0.570


chr13_+_44937025 0.570 NM_031431
COG3
component of oligomeric golgi complex 3
chr13_+_41744255 0.567 NM_016248
AKAP11
A kinase (PRKA) anchor protein 11
chr6_+_3966499 0.562 NM_003913
PRPF4B
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
chr6_+_147567200 0.561 NM_001127715
NM_139244
STXBP5

syntaxin binding protein 5 (tomosyn)

chr15_+_66357456 0.549 FEM1B
fem-1 homolog b (C. elegans)
chr8_+_11179724 0.549 MTMR9
myotubularin related protein 9
chr17_+_64019748 0.545 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr16_+_24648446 0.545 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr1_+_24842381 0.544 SRRM1
serine/arginine repetitive matrix 1
chr6_+_169844128 0.539 C6orf120
chromosome 6 open reading frame 120
chr16_-_8798973 0.538 NM_015421
TMEM186
transmembrane protein 186
chr14_-_77244073 0.538 NM_006020
ALKBH1
alkB, alkylation repair homolog 1 (E. coli)
chr14_-_49157076 0.534 NM_001001
RPL36AL
ribosomal protein L36a-like
chr4_-_153920326 0.533 NM_145720
TIGD4
tigger transposable element derived 4
chr2_+_176842368 0.530 NM_006554
MTX2
metaxin 2
chr14_+_22634585 0.529 C14orf119
chromosome 14 open reading frame 119
chr20_+_46971618 0.527 NM_006420
ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr11_-_72111027 0.527 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr2_+_178685396 0.527 NM_152945
RBM45
RNA binding motif protein 45
chr7_+_39629724 0.523 RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr16_-_23476138 0.521 NM_001083614
EARS2
glutamyl-tRNA synthetase 2, mitochondrial (putative)
chr14_+_22634517 0.521 C14orf119
chromosome 14 open reading frame 119
chr2_+_69974581 0.517 NM_006857
SNRNP27
small nuclear ribonucleoprotein 27kDa (U4/U6.U5)
chr3_+_185515543 0.515 NM_182917
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr2_-_196641682 0.514 NM_018897
DNAH7
dynein, axonemal, heavy chain 7
chr2_+_218790159 0.512 ARPC2
actin related protein 2/3 complex, subunit 2, 34kDa
chr13_+_76464044 0.512 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr15_+_65145248 0.511 NM_005902
SMAD3
SMAD family member 3
chr2_+_32435800 0.510 BIRC6
baculoviral IAP repeat containing 6
chr11_+_63363174 0.508 MARK2
MAP/microtubule affinity-regulating kinase 2
chr6_-_11490487 0.506 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr14_+_34831294 0.504 NM_002791
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_34831355 0.504 PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_+_68934855 0.504 SLC39A9
solute carrier family 39 (zinc transporter), member 9
chr9_-_132444639 0.504 LOC100272217
hypothetical LOC100272217
chr2_+_65308332 0.503 NM_001005386
NM_005722
ACTR2

ARP2 actin-related protein 2 homolog (yeast)

chr3_+_133861894 0.503 UBA5
ubiquitin-like modifier activating enzyme 5
chr19_+_50150486 0.503 CLPTM1
cleft lip and palate associated transmembrane protein 1
chr14_+_77244177 0.501 NM_031210
C14orf156
chromosome 14 open reading frame 156
chr4_+_153920563 0.501 ARFIP1
ADP-ribosylation factor interacting protein 1
chr17_-_71174816 0.501 NM_004259
NM_001003715
NM_001003716
RECQL5


RecQ protein-like 5


chr6_-_169844023 0.497 NM_182552
WDR27
WD repeat domain 27
chr14_+_22634621 0.496 NM_017924
C14orf119
chromosome 14 open reading frame 119
chr1_-_118273728 0.496 NM_001135589
NM_017686
GDAP2

ganglioside induced differentiation associated protein 2

chr8_+_125620523 0.494 NM_005005
NDUFB9
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa
chr4_+_56414565 0.492 NM_001024924
NM_018261
NM_178237
EXOC1


exocyst complex component 1


chr8_+_117847945 0.491 UTP23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr19_+_50150441 0.491 NM_001294
CLPTM1
cleft lip and palate associated transmembrane protein 1
chr1_+_109892741 0.490 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr7_+_39629665 0.490 NM_005402
RALA
v-ral simian leukemia viral oncogene homolog A (ras related)
chr14_+_96038479 0.483 PAPOLA
poly(A) polymerase alpha
chr8_+_117847922 0.482 NM_032334
UTP23
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_-_22634662 0.482 NM_001164814
NM_001164815
NM_014977
ACIN1


apoptotic chromatin condensation inducer 1


chr17_-_24013303 0.481 SDF2
stromal cell-derived factor 2
chr16_+_79626817 0.481 NM_015251
ATMIN
ATM interactor
chr14_+_54104099 0.480 SAMD4A
sterile alpha motif domain containing 4A
chr3_+_61522219 0.480 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr12_-_61283474 0.477 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr17_+_24013359 0.476 NM_003170
SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr4_+_153920382 0.474 NM_001025593
NM_001025595
NM_014447
ARFIP1


ADP-ribosylation factor interacting protein 1


chr22_-_45537081 0.473


chr16_+_48865521 0.472 ADCY7
adenylate cyclase 7
chr15_+_56850776 0.471 FAM63B
family with sequence similarity 63, member B
chr11_+_74950893 0.471 SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr20_+_3138055 0.470 NM_033453
NM_181493
ITPA

inosine triphosphatase (nucleoside triphosphate pyrophosphatase)

chr12_-_99184883 0.470 NM_152317
DEPDC4
DEP domain containing 4
chr20_+_43028533 0.469 NM_006282
STK4
serine/threonine kinase 4
chr2_+_239000395 0.469 ASB1
ankyrin repeat and SOCS box containing 1
chr14_+_77244191 0.469 C14orf156
chromosome 14 open reading frame 156
chr1_+_109892760 0.468 GNAI3
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr1_+_65658903 0.466 NM_001003679
NM_001003680
NM_002303
NM_001198681
LEPR


LEPROT
leptin receptor


leptin receptor overlapping transcript
chr16_+_23476334 0.466 NM_019116
UBFD1
ubiquitin family domain containing 1
chr14_+_101346032 0.466 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr2_+_53867571 0.465 NM_001127397
NM_001127398
NM_015701
ERLEC1


endoplasmic reticulum lectin 1


chr5_+_67620007 0.464 NM_181524
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_-_43212703 0.462 NM_001098207
HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr2_+_198089036 0.458 MOBKL3
MOB1, Mps One Binder kinase activator-like 3 (yeast)
chr15_+_88610181 0.457 NGRN
neugrin, neurite outgrowth associated
chr11_-_65860450 0.457 NM_004292
RIN1
Ras and Rab interactor 1
chr11_+_63362922 0.456 NM_001039469
NM_001163296
NM_001163297
NM_004954
MARK2



MAP/microtubule affinity-regulating kinase 2



chr17_+_24013320 0.455 SUPT6H
suppressor of Ty 6 homolog (S. cerevisiae)
chr17_+_55052185 0.451


chr16_+_72888231 0.451 PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_+_144325533 0.450 USP38
ubiquitin specific peptidase 38
chr6_+_26646548 0.450 NM_006353
HMGN4
high mobility group nucleosomal binding domain 4
chr3_+_180348818 0.449 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr17_+_59205289 0.449 NM_007372
NM_203499
DDX42

DEAD (Asp-Glu-Ala-Asp) box polypeptide 42

chr16_+_72888161 0.448 NM_002811
PSMD7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_+_144325502 0.446 NM_032557
USP38
ubiquitin specific peptidase 38
chr12_+_99184977 0.446 SCYL2
SCY1-like 2 (S. cerevisiae)
chr20_+_43028590 0.443 STK4
serine/threonine kinase 4
chr1_+_94656517 0.442 NM_001122674
NM_002858
ABCD3

ATP-binding cassette, sub-family D (ALD), member 3

chr9_+_4669557 0.442 NM_017913
CDC37L1
cell division cycle 37 homolog (S. cerevisiae)-like 1
chr3_+_144203061 0.441 NM_001080415
U2SURP
U2 snRNP-associated SURP domain containing
chr2_+_64605049 0.440 AFTPH
aftiphilin
chr17_+_55139644 0.440 NM_030938
VMP1
vacuole membrane protein 1
chr8_-_125620466 0.440 NM_001146160
NM_032026
TATDN1

TatD DNase domain containing 1

chr14_+_52243645 0.440 NM_002806
PSMC6
proteasome (prosome, macropain) 26S subunit, ATPase, 6
chr12_+_99185289 0.439 SCYL2
SCY1-like 2 (S. cerevisiae)
chr21_+_44256630 0.439 NM_003274
TRAPPC10
trafficking protein particle complex 10
chr2_+_118288754 0.439 DDX18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr2_+_161725172 0.437 TANK
TRAF family member-associated NFKB activator
chr17_+_33761234 0.435 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr12_-_52868855 0.434 NM_014311
SMUG1
single-strand-selective monofunctional uracil-DNA glycosylase 1
chr14_+_101345878 0.432 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr15_+_56850681 0.432 NM_001040450
NM_001040453
FAM63B

family with sequence similarity 63, member B

chr14_-_22634134 0.432 ACIN1
apoptotic chromatin condensation inducer 1
chr3_+_140545528 0.430 NM_020191
MRPS22
mitochondrial ribosomal protein S22
chr2_+_182464713 0.429 NM_001130445
NM_006751
SSFA2

sperm specific antigen 2

chr17_-_24013259 0.429 SDF2
stromal cell-derived factor 2
chr20_-_48741481 0.429


chr5_+_61910318 0.428 NM_181506
LRRC70
leucine rich repeat containing 70
chr17_+_55139743 0.428 VMP1
vacuole membrane protein 1
chr4_+_57028503 0.427 NM_006947
SRP72
signal recognition particle 72kDa
chr3_+_61522310 0.427 PTPRG
protein tyrosine phosphatase, receptor type, G
chr17_+_59205244 0.426


chr2_-_201461945 0.426 NM_032472
NM_130906
PPIL3

peptidylprolyl isomerase (cyclophilin)-like 3

chr17_+_55139792 0.424 VMP1
vacuole membrane protein 1
chr5_+_72830029 0.423 BTF3
basic transcription factor 3
chr15_+_88609837 0.423 NM_001033088
NGRN
neugrin, neurite outgrowth associated
chr10_+_18988282 0.423 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr1_+_65658718 0.422 NM_001198683
NM_017526
LEPROT

leptin receptor overlapping transcript

chr10_-_43212681 0.419 HNRNPF
heterogeneous nuclear ribonucleoprotein F
chr5_+_72830003 0.417 NM_001037637
NM_001207
BTF3

basic transcription factor 3

chr4_+_119825983 0.417 NM_020961
METTL14
methyltransferase like 14
chr1_+_94656556 0.415 ABCD3
ATP-binding cassette, sub-family D (ALD), member 3
chr17_+_64019693 0.414 NM_212471
PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr17_+_55139793 0.413 VMP1
vacuole membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 7.37e-24 GO:0044260 cellular macromolecule metabolic process
1.21 2.24e-18 GO:0043170 macromolecule metabolic process
1.17 3.03e-17 GO:0044237 cellular metabolic process
1.29 5.12e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.31 2.03e-13 GO:0090304 nucleic acid metabolic process
1.34 3.96e-13 GO:0010467 gene expression
1.15 1.10e-12 GO:0044238 primary metabolic process
1.27 2.91e-12 GO:0044267 cellular protein metabolic process
1.34 6.79e-12 GO:0016070 RNA metabolic process
1.13 9.09e-12 GO:0008152 metabolic process
1.32 1.20e-10 GO:0009059 macromolecule biosynthetic process
1.22 3.74e-10 GO:0034641 cellular nitrogen compound metabolic process
1.59 3.82e-10 GO:0016071 mRNA metabolic process
1.32 3.94e-10 GO:0034645 cellular macromolecule biosynthetic process
1.08 6.96e-10 GO:0009987 cellular process
1.21 1.85e-09 GO:0006807 nitrogen compound metabolic process
1.57 2.61e-09 GO:0044265 cellular macromolecule catabolic process
1.50 8.12e-09 GO:0006396 RNA processing
1.72 1.01e-08 GO:0006511 ubiquitin-dependent protein catabolic process
1.70 1.22e-08 GO:0070647 protein modification by small protein conjugation or removal
1.22 1.35e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.19 1.40e-08 GO:0071840 cellular component organization or biogenesis
1.67 1.45e-08 GO:0030163 protein catabolic process
1.51 1.87e-08 GO:0009057 macromolecule catabolic process
1.38 2.14e-08 GO:0007049 cell cycle
1.68 4.69e-08 GO:0051603 proteolysis involved in cellular protein catabolic process
1.68 4.88e-08 GO:0044257 cellular protein catabolic process
1.69 5.81e-08 GO:0019941 modification-dependent protein catabolic process
1.68 1.02e-07 GO:0043632 modification-dependent macromolecule catabolic process
1.43 1.18e-07 GO:0046907 intracellular transport
1.42 1.54e-07 GO:0022402 cell cycle process
1.19 1.66e-07 GO:0016043 cellular component organization
1.20 1.69e-07 GO:0019538 protein metabolic process
1.28 2.09e-07 GO:0006996 organelle organization
1.68 2.12e-07 GO:0006412 translation
1.49 2.38e-07 GO:0000278 mitotic cell cycle
1.71 2.89e-07 GO:0032446 protein modification by small protein conjugation
1.21 3.01e-07 GO:0071842 cellular component organization at cellular level
1.34 3.73e-07 GO:0044248 cellular catabolic process
1.59 5.36e-07 GO:0006397 mRNA processing
1.73 5.52e-07 GO:0016567 protein ubiquitination
1.43 1.29e-06 GO:0022403 cell cycle phase
1.21 4.32e-06 GO:0044249 cellular biosynthetic process
1.88 4.85e-06 GO:0010498 proteasomal protein catabolic process
1.88 4.85e-06 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
1.54 5.06e-06 GO:0016032 viral reproduction
1.20 8.76e-06 GO:0009058 biosynthetic process
1.31 2.95e-05 GO:0051649 establishment of localization in cell
1.28 5.80e-05 GO:0051641 cellular localization
1.40 1.12e-04 GO:0051726 regulation of cell cycle
1.71 1.23e-04 GO:0000375 RNA splicing, via transesterification reactions
1.34 1.38e-04 GO:0015031 protein transport
1.57 1.49e-04 GO:0051325 interphase
1.33 1.50e-04 GO:0045184 establishment of protein localization
1.71 1.55e-04 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.71 1.55e-04 GO:0000398 nuclear mRNA splicing, via spliceosome
1.36 1.60e-04 GO:0016192 vesicle-mediated transport
1.57 1.91e-04 GO:0008380 RNA splicing
1.26 1.93e-04 GO:0033036 macromolecule localization
2.06 2.21e-04 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.15 2.68e-04 GO:0060255 regulation of macromolecule metabolic process
1.25 2.81e-04 GO:0009056 catabolic process
1.30 3.28e-04 GO:0032268 regulation of cellular protein metabolic process
1.93 3.29e-04 GO:0031398 positive regulation of protein ubiquitination
1.33 3.51e-04 GO:0033554 cellular response to stress
1.55 3.80e-04 GO:0051329 interphase of mitotic cell cycle
1.42 4.70e-04 GO:0006974 response to DNA damage stimulus
1.56 1.05e-03 GO:0010608 posttranscriptional regulation of gene expression
1.27 1.35e-03 GO:0008104 protein localization
2.03 1.65e-03 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
1.27 2.21e-03 GO:0051246 regulation of protein metabolic process
2.10 2.52e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.75 2.72e-03 GO:0000082 G1/S transition of mitotic cell cycle
1.57 2.96e-03 GO:0032269 negative regulation of cellular protein metabolic process
1.98 3.94e-03 GO:0051351 positive regulation of ligase activity
2.00 4.45e-03 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.84 4.93e-03 GO:0042770 signal transduction in response to DNA damage
1.82 5.32e-03 GO:0051320 S phase
2.07 5.34e-03 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.89 6.48e-03 GO:0051340 regulation of ligase activity
1.98 6.85e-03 GO:0000216 M/G1 transition of mitotic cell cycle
1.98 6.85e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
1.98 6.85e-03 GO:0051443 positive regulation of ubiquitin-protein ligase activity
1.98 6.85e-03 GO:0071779 G1/S transition checkpoint
1.43 7.20e-03 GO:0006886 intracellular protein transport
1.82 9.18e-03 GO:0000077 DNA damage checkpoint
1.19 9.95e-03 GO:0006464 protein modification process
2.01 1.02e-02 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.89 1.12e-02 GO:0051438 regulation of ubiquitin-protein ligase activity
1.70 1.17e-02 GO:0031396 regulation of protein ubiquitination
1.93 1.18e-02 GO:2000045 regulation of G1/S transition of mitotic cell cycle
2.09 1.21e-02 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
2.09 1.21e-02 GO:0072395 signal transduction involved in cell cycle checkpoint
2.09 1.21e-02 GO:0072401 signal transduction involved in DNA integrity checkpoint
2.09 1.21e-02 GO:0072404 signal transduction involved in G1/S transition checkpoint
2.09 1.21e-02 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
2.09 1.21e-02 GO:0072422 signal transduction involved in DNA damage checkpoint
2.09 1.21e-02 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
2.09 1.21e-02 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
1.36 1.27e-02 GO:0070727 cellular macromolecule localization
1.36 1.33e-02 GO:0034613 cellular protein localization
1.52 1.37e-02 GO:0051248 negative regulation of protein metabolic process
2.05 1.48e-02 GO:0071158 positive regulation of cell cycle arrest
1.79 1.80e-02 GO:0000084 S phase of mitotic cell cycle
1.98 2.07e-02 GO:0051352 negative regulation of ligase activity
1.98 2.07e-02 GO:0051444 negative regulation of ubiquitin-protein ligase activity
1.64 2.19e-02 GO:0006417 regulation of translation
1.08 2.41e-02 GO:0050794 regulation of cellular process
1.27 2.78e-02 GO:0016265 death
1.12 2.99e-02 GO:0031323 regulation of cellular metabolic process
1.46 3.04e-02 GO:0031401 positive regulation of protein modification process
1.74 3.58e-02 GO:0031570 DNA integrity checkpoint
1.26 3.76e-02 GO:0008219 cell death
1.45 3.76e-02 GO:0048285 organelle fission
1.42 4.18e-02 GO:0010564 regulation of cell cycle process
1.55 4.21e-02 GO:0071843 cellular component biogenesis at cellular level

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.13 1.74e-38 GO:0044424 intracellular part
1.12 1.47e-37 GO:0005622 intracellular
1.15 7.05e-34 GO:0043229 intracellular organelle
1.15 7.26e-34 GO:0043226 organelle
1.16 1.93e-31 GO:0043231 intracellular membrane-bounded organelle
1.16 2.23e-31 GO:0043227 membrane-bounded organelle
1.21 2.21e-23 GO:0005634 nucleus
1.33 1.53e-18 GO:0031974 membrane-enclosed lumen
1.33 2.12e-18 GO:0043233 organelle lumen
1.33 4.57e-18 GO:0070013 intracellular organelle lumen
1.13 1.64e-17 GO:0005737 cytoplasm
1.18 6.17e-17 GO:0044446 intracellular organelle part
1.17 5.26e-16 GO:0044422 organelle part
1.16 1.60e-15 GO:0044444 cytoplasmic part
1.32 2.56e-15 GO:0044428 nuclear part
1.31 1.36e-13 GO:0005829 cytosol
1.33 2.35e-13 GO:0031981 nuclear lumen
1.59 4.59e-11 GO:0030529 ribonucleoprotein complex
1.19 3.76e-10 GO:0032991 macromolecular complex
1.31 2.58e-08 GO:0005654 nucleoplasm
1.20 4.65e-08 GO:0043228 non-membrane-bounded organelle
1.20 4.65e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.86 2.17e-05 GO:0005681 spliceosomal complex
1.03 2.73e-05 GO:0044464 cell part
1.72 2.90e-05 GO:0031252 cell leading edge
1.03 2.93e-05 GO:0005623 cell
1.42 6.45e-05 GO:0005730 nucleolus
1.80 6.69e-05 GO:0000151 ubiquitin ligase complex
1.15 2.10e-04 GO:0043234 protein complex
1.23 6.38e-04 GO:0005739 mitochondrion
1.91 1.18e-03 GO:0001726 ruffle
1.56 8.66e-03 GO:0005840 ribosome
1.40 1.45e-02 GO:0005815 microtubule organizing center
1.96 1.47e-02 GO:0000502 proteasome complex
2.36 2.43e-02 GO:0030532 small nuclear ribonucleoprotein complex
1.81 3.49e-02 GO:0031461 cullin-RING ubiquitin ligase complex
1.81 3.49e-02 GO:0071013 catalytic step 2 spliceosome

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 1.06e-20 GO:0005515 protein binding
1.07 2.93e-13 GO:0005488 binding
1.49 9.78e-13 GO:0003723 RNA binding
1.21 6.22e-11 GO:0003676 nucleic acid binding
2.05 2.14e-04 GO:0008135 translation factor activity, nucleic acid binding
1.28 7.18e-03 GO:0019899 enzyme binding
2.17 9.86e-03 GO:0003743 translation initiation factor activity
1.14 3.13e-02 GO:0000166 nucleotide binding