Motif ID: HNF1A.p2

Z-value: 1.405


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HNF1Achr12_+_1199006770.185.0e-01Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_750281 1.981 PTBP1
polypyrimidine tract binding protein 1
chr1_+_93830106 1.919 LOC100129046
hypothetical LOC100129046
chr1_+_93830169 1.688 LOC100129046
hypothetical LOC100129046
chr7_+_45894480 1.608 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr4_+_74520796 1.466 NM_001134
AFP
alpha-fetoprotein
chr21_-_35153664 1.437 RUNX1
runt-related transcription factor 1
chr14_+_20226762 1.186 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr3_+_120799411 1.158 NM_015900
PLA1A
phospholipase A1 member A
chr7_-_47545717 1.133 NM_022748
TNS3
tensin 3
chr4_+_74566325 1.083 NM_001133
AFM
afamin
chr20_+_42463419 1.031 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_-_7869068 0.944 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_42463350 0.944 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_-_17589122 0.932 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chrX_-_105169370 0.929 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr20_+_42463387 0.922 HNF4A
hepatocyte nuclear factor 4, alpha
chr3_-_168674502 0.873 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr20_+_42463279 0.867 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr11_-_117200618 0.854 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr9_-_122852356 0.850 NM_001735
C5
complement component 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
25.49 1.14e-02 GO:0009750 response to fructose stimulus
10.93 1.69e-02 GO:0030195 negative regulation of blood coagulation
10.55 2.09e-02 GO:0050819 negative regulation of coagulation
8.50 4.53e-03 GO:0061041 regulation of wound healing
6.04 2.04e-02 GO:0009746 response to hexose stimulus
5.96 2.27e-02 GO:0034284 response to monosaccharide stimulus
1.65 2.84e-02 GO:0042221 response to chemical stimulus
1.32 3.79e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
enrichment   p-value GO term description
8.68 5.87e-04 GO:0031093 platelet alpha granule lumen
8.50 6.92e-04 GO:0034774 secretory granule lumen
8.16 9.52e-04 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
7.93 4.53e-03 GO:0005903 brush border
7.85 1.29e-03 GO:0031983 vesicle lumen
7.03 2.97e-03 GO:0031091 platelet alpha granule
4.86 3.72e-05 GO:0016324 apical plasma membrane
4.11 1.69e-04 GO:0045177 apical part of cell
2.64 5.43e-06 GO:0005615 extracellular space
2.30 3.66e-05 GO:0044421 extracellular region part
1.93 3.52e-06 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
10.93 4.21e-03 GO:0015020 glucuronosyltransferase activity
8.11 6.36e-03 GO:0043498 cell surface binding