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Motif ID: HNF1A.p2

Z-value: 1.405

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_750281	1.981		PTBP1	polypyrimidine tract binding protein 1
chr1_+_93830106	1.919		LOC100129046	hypothetical LOC100129046
chr1_+_93830169	1.688		LOC100129046	hypothetical LOC100129046
chr7_+_45894480	1.608	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr4_+_74520796	1.466	NM_001134	AFP	alpha-fetoprotein
chr21_-_35153664	1.437		RUNX1	runt-related transcription factor 1
chr14_+_20226762	1.186	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr3_+_120799411	1.158	NM_015900	PLA1A	phospholipase A1 member A
chr7_-_47545717	1.133	NM_022748	TNS3	tensin 3
chr4_+_74566325	1.083	NM_001133	AFM	afamin
chr20_+_42463419	1.031		HNF4A	hepatocyte nuclear factor 4, alpha
chr20_-_7869068	0.944	NM_017545	HAO1	hydroxyacid oxidase (glycolate oxidase) 1
chr20_+_42463350	0.944		HNF4A	hepatocyte nuclear factor 4, alpha
chr20_-_17589122	0.932		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chrX_-_105169370	0.929	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr20_+_42463387	0.922		HNF4A	hepatocyte nuclear factor 4, alpha
chr3_-_168674502	0.873	NM_006217	SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2
chr20_+_42463279	0.867	NM_000457 NM_178849 NM_178850	HNF4A	hepatocyte nuclear factor 4, alpha
chr11_-_117200618	0.854	NM_001127489 NM_001680	FXYD2	FXYD domain containing ion transport regulator 2
chr9_-_122852356	0.850	NM_001735	C5	complement component 5
chr4_+_74488910	0.797		ALB	albumin
chrX_+_107174855	0.789	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr20_+_42417502	0.776		HNF4A	hepatocyte nuclear factor 4, alpha
chrX_-_33056464	0.770	NM_004010 NM_004009	DMD	dystrophin
chr17_+_71065478	0.768		LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr4_+_74488947	0.762		ALB	albumin
chr16_-_54466709	0.760	NM_001143685 NM_145024	CES5A	carboxylesterase 5A
chr8_-_18585721	0.748		PSD3	pleckstrin and Sec7 domain containing 3
chr4_+_74488835	0.724	NM_000477	ALB	albumin
chr8_+_21967008	0.720	NM_001114137	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr22_+_43476710	0.701	NM_181333	PRR5	proline rich 5 (renal)
chr20_+_42417752	0.698	NM_001030003 NM_001030004 NM_175914	HNF4A	hepatocyte nuclear factor 4, alpha
chr5_+_175908948	0.698	NM_017675	CDHR2	cadherin-related family member 2
chr12_+_52697160	0.696		HOXC5 HOXC6	homeobox C5 homeobox C6
chr11_+_46697345	0.687		F2	coagulation factor II (thrombin)
chr21_-_46399900	0.685	NM_006657 NM_206965	FTCD	formiminotransferase cyclodeaminase
chr1_+_48460943	0.684	NM_001011547 NM_001135181	SLC5A9	solute carrier family 5 (sodium/glucose cotransporter), member 9
chr9_+_129900590	0.662		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_+_46697335	0.659		F2	coagulation factor II (thrombin)
chr10_+_135190855	0.656	NM_000773	CYP2E1	cytochrome P450, family 2, subfamily E, polypeptide 1
chr3_-_166278969	0.645	NM_001041	SI	sucrase-isomaltase (alpha-glucosidase)
chr1_-_157950898	0.643	NM_000567	CRP	C-reactive protein, pentraxin-related
chr4_-_977163	0.642	NM_022042 NM_134425 NM_213613	SLC26A1	solute carrier family 26 (sulfate transporter), member 1
chr11_+_46697312	0.636	NM_000506	F2	coagulation factor II (thrombin)
chr9_+_129900637	0.636	NM_052901 NM_001006643	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr1_+_15637521	0.633	NM_007272	CTRC	chymotrypsin C (caldecrin)
chr4_+_169250281	0.618	NM_007193	ANXA10	annexin A10
chr13_-_98757634	0.606	NM_004951	GPR183	G protein-coupled receptor 183
chr4_+_3413489	0.603	NM_001528	HGFAC	HGF activator
chr2_-_87102453	0.600	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr5_-_147191334	0.599		SPINK1	serine peptidase inhibitor, Kazal type 1
chr2_-_63518589	0.598	NM_001042692	WDPCP	WD repeat containing planar cell polarity effector
chr4_+_74497998	0.580		ALB	albumin
chr22_-_36836478	0.575		BAIAP2L2	BAI1-associated protein 2-like 2
chr10_+_44726635	0.564	NM_001123376	TMEM72	transmembrane protein 72
chr22_-_36836620	0.552	NM_025045	BAIAP2L2	BAI1-associated protein 2-like 2
chrX_-_65752570	0.534	NM_021783	EDA2R	ectodysplasin A2 receptor
chr22_-_41685827	0.530	NM_001184971	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr17_-_202557	0.529		RPH3AL	rabphilin 3A-like (without C2 domains)
chr7_+_94130673	0.529		PEG10	paternally expressed 10
chr5_-_147191428	0.523	NM_003122	SPINK1	serine peptidase inhibitor, Kazal type 1
chr3_+_187866464	0.519	NM_000412	HRG	histidine-rich glycoprotein
chr2_-_99284070	0.511	NM_174898	LYG1	lysozyme G-like 1
chr4_+_74498042	0.504		ALB	albumin
chr4_+_3413457	0.500		HGFAC	HGF activator
chr2_+_234266250	0.499	NM_001072	UGT1A6	UDP glucuronosyltransferase 1 family, polypeptide A6
chr10_+_101532450	0.485	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr8_+_76482661	0.483		HNF4G	hepatocyte nuclear factor 4, gamma
chr9_-_21295311	0.478	NM_002169	IFNA5	interferon, alpha 5
chr3_+_185430910	0.467	NM_138345	VWA5B2	von Willebrand factor A domain containing 5B2
chr12_+_52696908	0.459	NM_014620 NM_153693	HOXC4 HOXC6	homeobox C4 homeobox C6
chr3_-_193928038	0.457	NM_004113	FGF12	fibroblast growth factor 12
chr6_+_54281161	0.454	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr13_-_32658215	0.449	NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr19_+_11211282	0.436	NM_018687	LOC55908	hepatocellular carcinoma-associated gene TD26
chr1_-_20014180	0.432	NM_019062	RNF186	ring finger protein 186
chr8_-_6407882	0.431	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr13_+_52500830	0.428	NM_006418	OLFM4	olfactomedin 4
chr10_+_111755715	0.403	NM_019903	ADD3	adducin 3 (gamma)
chr17_-_202617	0.402	NM_001190411 NM_001190412 NM_001190413 NM_006987	RPH3AL	rabphilin 3A-like (without C2 domains)
chr1_+_17779528	0.399	NM_001011722	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_161043214	0.399	NM_000301 NM_001168338	PLG	plasminogen
chr11_+_551449	0.395	NM_001143994 NM_003475	RASSF7	Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr21_-_18697829	0.392	NM_002772	TMPRSS15	transmembrane protease, serine 15
chr6_-_74284522	0.391		EEF1A1	eukaryotic translation elongation factor 1 alpha 1
chr1_+_81544432	0.391		LPHN2	latrophilin 2
chr20_+_41621119	0.384		SGK2	serum/glucocorticoid regulated kinase 2
chr12_+_21417068	0.379	NM_000415	IAPP	islet amyloid polypeptide
chr11_+_64079665	0.374	NM_018484	SLC22A11	solute carrier family 22 (organic anion/urate transporter), member 11
chr2_+_27573206	0.369	NM_001486	GCKR	glucokinase (hexokinase 4) regulator
chr16_+_21152516	0.364	NM_145865	ANKS4B	ankyrin repeat and sterile alpha motif domain containing 4B
chr19_+_44308224	0.357	NM_001014831 NM_001014832 NM_001014834 NM_001014835 NM_005884	PAK4	p21 protein (Cdc42/Rac)-activated kinase 4
chr14_+_38805251	0.353	NM_203356	CTAGE5	CTAGE family, member 5
chr2_+_234191029	0.353	NM_019076	UGT1A8	UDP glucuronosyltransferase 1 family, polypeptide A8
chr20_+_41621079	0.350	NM_170693	SGK2	serum/glucocorticoid regulated kinase 2
chr1_-_103269356	0.349		COL11A1	collagen, type XI, alpha 1
chr7_-_44547382	0.347	NM_001101648 NM_013389	NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1
chr1_-_195302973	0.341	NM_001994	F13B	coagulation factor XIII, B polypeptide
chr16_-_46826588	0.337	NM_032583 NM_145186	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr6_+_64289585	0.336		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr11_-_121492010	0.334	NM_001001786	BLID	BH3-like motif containing, cell death inducer
chr17_+_71154240	0.332	NM_001162997	LOC100130933	hypothetical protein LOC100130933
chr20_+_9236446	0.324	NM_000933	PLCB4	phospholipase C, beta 4
chr5_+_176446425	0.323	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr10_+_101532544	0.322		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_-_87694218	0.315	NM_198901	SRI	sorcin
chr11_+_26310253	0.314	NM_031418	ANO3	anoctamin 3
chr1_+_198263352	0.308	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr17_+_76549658	0.305		RPTOR	regulatory associated protein of MTOR, complex 1
chr10_+_115302767	0.301	NM_004132	HABP2	hyaluronan binding protein 2
chr11_+_63282639	0.300		RTN3	reticulon 3
chr4_-_155731288	0.298	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr4_+_154345039	0.292	NM_015271	TRIM2	tripartite motif containing 2
chr3_+_108578877	0.282	NM_032600	CCDC54	coiled-coil domain containing 54
chr17_-_19290745	0.282
chr10_+_114144512	0.279		ACSL5	acyl-CoA synthetase long-chain family member 5
chr16_+_74901235	0.277	NM_138994	CNTNAP4	contactin associated protein-like 4
chr16_-_20271530	0.276	NM_001008389 NM_003361	UMOD	uromodulin
chr14_-_91403609	0.267	NM_001128596	TC2N	tandem C2 domains, nuclear
chr12_+_10222823	0.263	NM_153022	C12orf59	chromosome 12 open reading frame 59
chr13_+_50813168	0.262	NM_001101320	SERPINE3	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr10_+_5126613	0.260		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr2_-_6924092	0.258		CMPK2	cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr1_+_157824239	0.258	NM_001639	APCS	amyloid P component, serum
chrX_-_131375217	0.258	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr15_-_42756377	0.258	NM_001145112	PATL2	protein associated with topoisomerase II homolog 2 (yeast)
chr11_-_8695974	0.251		ST5	suppression of tumorigenicity 5
chr1_-_42402973	0.249	NM_033553	GUCA2A	guanylate cyclase activator 2A (guanylin)
chrX_+_115215985	0.249	NM_000686	AGTR2	angiotensin II receptor, type 2
chr6_-_119512035	0.246	NM_001100411	FAM184A	family with sequence similarity 184, member A
chr14_+_21203136	0.244	NM_001001912	OR4E2	olfactory receptor, family 4, subfamily E, member 2
chr10_+_5126589	0.243		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_+_38306339	0.242	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr11_+_64114857	0.241	NM_144585 NM_153378	SLC22A12	solute carrier family 22 (organic anion/urate transporter), member 12
chr15_-_49184764	0.240	NM_207381	TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr16_+_88224175	0.240		DPEP1	dipeptidase 1 (renal)
chr10_+_5126556	0.236	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr2_+_87828718	0.233	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr1_-_202449659	0.230	NM_198447	GOLT1A	golgi transport 1A
chr7_+_72913424	0.230	NM_182504	WBSCR28	Williams-Beuren syndrome chromosome region 28
chr8_-_108579270	0.230	NM_001146	ANGPT1	angiopoietin 1
chr6_-_33862690	0.229	NM_001143944	LEMD2	LEM domain containing 2
chr22_+_30769211	0.229		SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr4_-_100492854	0.229	NM_000669	ADH1C	alcohol dehydrogenase 1C (class I), gamma polypeptide
chr20_+_35406497	0.226	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr22_-_30981317	0.224	NM_014227	SLC5A4	solute carrier family 5 (low affinity glucose cotransporter), member 4
chr5_+_76470829	0.223
chr17_+_77910411	0.222	NM_207459	TEX19	testis expressed 19
chr11_+_65026382	0.220
chr4_+_155703581	0.220	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr16_+_56286212	0.218	NM_032269	CCDC135	coiled-coil domain containing 135
chr5_+_140509803	0.217	NM_018939	PCDHB6	protocadherin beta 6
chr13_-_40491405	0.214		ELF1	E74-like factor 1 (ets domain transcription factor)
chr16_+_79829794	0.213	NM_017429	BCMO1	beta-carotene 15,15'-monooxygenase 1
chr22_+_43476755	0.210	NM_181334	PRR5-ARHGAP8 PRR5	PRR5-ARHGAP8 readthrough proline rich 5 (renal)
chr1_-_36562341	0.208	NM_018166	FAM176B	family with sequence similarity 176, member B
chr16_+_20682812	0.206	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chr19_-_63556632	0.204	NM_130786	A1BG	alpha-1-B glycoprotein
chr19_-_47790820	0.204	NM_001816	CEACAM8	carcinoembryonic antigen-related cell adhesion molecule 8
chr4_-_101658094	0.201	NM_001159694 NM_016242	EMCN	endomucin
chr8_-_87311624	0.198	NM_138817	SLC7A13	solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr1_+_55044323	0.198	NM_001110533 NM_152607	C1orf177	chromosome 1 open reading frame 177
chr8_+_32905027	0.197
chr5_+_147775652	0.192		FBXO38	F-box protein 38
chr12_+_9871343	0.191	NM_016523	KLRF1	killer cell lectin-like receptor subfamily F, member 1
chrX_+_35974973	0.185	NM_173695	CXorf59	chromosome X open reading frame 59
chr6_+_131613196	0.184	NM_004842 NM_138633	AKAP7	A kinase (PRKA) anchor protein 7
chr1_-_157551072	0.182	NM_001004467	OR10J3	olfactory receptor, family 10, subfamily J, member 3
chr4_+_25267183	0.181	NM_001177999	SLC34A2	solute carrier family 34 (sodium phosphate), member 2
chr4_-_70861301	0.178	NM_001891	CSN2	casein beta
chr19_+_46201665	0.178		CYP2B6	cytochrome P450, family 2, subfamily B, polypeptide 6
chr6_-_165643064	0.176	NM_144980	C6orf118	chromosome 6 open reading frame 118
chr22_+_30769250	0.173		SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr2_+_97696462	0.171	NM_001079	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr14_+_38772870	0.169	NM_054024	MIA2	melanoma inhibitory activity 2
chr2_-_1905508	0.164		MYT1L	myelin transcription factor 1-like
chr14_+_64240996	0.163		PLEKHG3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_1925880	0.162		MYT1L	myelin transcription factor 1-like
chr14_-_106170414	0.161		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_-_133008834	0.157	NM_138327	TAAR1	trace amine associated receptor 1
chr3_-_171070314	0.154	NM_024727	LRRC31	leucine rich repeat containing 31
chr16_-_21344158	0.154	NM_130464	NPIPL3	nuclear pore complex interacting protein-like 3
chr22_+_30769103	0.152		SLC5A1	solute carrier family 5 (sodium/glucose cotransporter), member 1
chr9_-_70345549	0.150	NM_153237	C9orf71	chromosome 9 open reading frame 71
chr16_+_88224276	0.150		DPEP1	dipeptidase 1 (renal)
chr4_+_124537334	0.150	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr4_-_110942783	0.149	NM_000204	CFI	complement factor I
chr1_-_197173159	0.149		LOC100131234	familial acute myelogenous leukemia related factor
chr5_+_132460779	0.148		HSPA4	heat shock 70kDa protein 4
chr3_+_150675117	0.148	NM_004617	TM4SF4	transmembrane 4 L six family member 4
chr12_-_101398470	0.148		IGF1	insulin-like growth factor 1 (somatomedin C)
chr20_+_56848127	0.148		GNAS	GNAS complex locus
chr17_+_69781980	0.147	NM_001172810 NM_023036	DNAI2	dynein, axonemal, intermediate chain 2
chr3_-_127810087	0.147	NM_001039783	TXNRD3IT1	thioredoxin reductase 3 intronic transcript 1
chr3_+_150675169	0.143		TM4SF4	transmembrane 4 L six family member 4
chr17_-_10393664	0.142	NM_001100112 NM_017534	MYH2	myosin, heavy chain 2, skeletal muscle, adult
chr10_-_129581192	0.142	NM_152311	CLRN3	clarin 3
chr3_-_162572441	0.139	NM_001040100	C3orf57	chromosome 3 open reading frame 57
chr14_-_93829113	0.137	NM_016186	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr6_+_25862905	0.137	NM_005495	SLC17A4	solute carrier family 17 (sodium phosphate), member 4

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
8.50	4.53e-03	GO:0061041	regulation of wound healing
25.49	1.14e-02	GO:0009750	response to fructose stimulus
10.93	1.69e-02	GO:0030195	negative regulation of blood coagulation
6.04	2.04e-02	GO:0009746	response to hexose stimulus
10.55	2.09e-02	GO:0050819	negative regulation of coagulation
5.96	2.27e-02	GO:0034284	response to monosaccharide stimulus
1.65	2.84e-02	GO:0042221	response to chemical stimulus
1.32	3.79e-02	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.93	3.52e-06	GO:0005576	extracellular region
2.64	5.43e-06	GO:0005615	extracellular space
2.30	3.66e-05	GO:0044421	extracellular region part
4.86	3.72e-05	GO:0016324	apical plasma membrane
4.11	1.69e-04	GO:0045177	apical part of cell
8.68	5.87e-04	GO:0031093	platelet alpha granule lumen
8.50	6.92e-04	GO:0034774	secretory granule lumen
8.16	9.52e-04	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
7.85	1.29e-03	GO:0031983	vesicle lumen
7.03	2.97e-03	GO:0031091	platelet alpha granule
7.93	4.53e-03	GO:0005903	brush border

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
10.93	4.21e-03	GO:0015020	glucuronosyltransferase activity
8.11	6.36e-03	GO:0043498	cell surface binding