Motif ID: KLF12.p2

Z-value: 5.180


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_73605914-0.572.0e-02Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_14121728 7.659 LPHN1
latrophilin 1
chr19_+_2200112 6.126 NM_000479
 AMH
anti-Mullerian hormone
chr19_-_3928516 5.995 EEF2
eukaryotic translation elongation factor 2
chrX_+_67965517 5.621 NM_004429
 EFNB1
ephrin-B1
chr16_-_66535457 5.349 NM_000229
 LCAT
lecithin-cholesterol acyltransferase
chrX_+_152454773 5.189 NM_001001344
NM_021949
 ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr19_+_16005929 4.997 FLJ25328
hypothetical LOC148231
chr16_+_67697622 4.934 NM_138612
 HAS3
hyaluronan synthase 3
chr16_-_66535923 4.757 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr1_+_23990228 4.729 NM_007260
 LYPLA2
lysophospholipase II
chr17_+_24095135 4.719 NM_004295
 TRAF4
TNF receptor-associated factor 4
chrX_+_152699616 4.702 NM_001170760
NM_001170761
NM_014370
 SRPK3


SRSF protein kinase 3


chr2_+_232281491 4.695 PTMA
prothymosin, alpha
chr19_+_5641307 4.663 RPL36
ribosomal protein L36
chr5_+_137829065 4.643 EGR1
early growth response 1
chr17_-_1495742 4.612 NM_003693
NM_145350
NM_145352
 SCARF1


scavenger receptor class F, member 1


chr19_+_5641270 4.566 NM_033643
 RPL36
ribosomal protein L36
chr9_-_129752687 4.504 NM_203305
 FAM102A
family with sequence similarity 102, member A
chr19_+_5641332 4.454 NM_015414
 RPL36
ribosomal protein L36
chr20_+_61394982 4.322 NM_020882
 COL20A1
collagen, type XX, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 130 entries
enrichment   p-value GO term description
2.70 9.15e-04 GO:0060349 bone morphogenesis
2.56 1.77e-02 GO:0003014 renal system process
2.43 1.30e-03 GO:0060348 bone development
2.22 3.50e-02 GO:0045667 regulation of osteoblast differentiation
2.00 2.74e-02 GO:0021953 central nervous system neuron differentiation
1.98 6.42e-05 GO:0048705 skeletal system morphogenesis
1.97 5.17e-03 GO:0030278 regulation of ossification
1.83 9.46e-03 GO:0010959 regulation of metal ion transport
1.78 1.59e-02 GO:0001503 ossification
1.71 3.39e-03 GO:0003012 muscle system process
1.62 2.68e-02 GO:0007517 muscle organ development
1.59 1.76e-04 GO:0007411 axon guidance
1.59 2.36e-04 GO:0001501 skeletal system development
1.59 3.96e-03 GO:0045596 negative regulation of cell differentiation
1.55 3.15e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.55 1.46e-03 GO:0060284 regulation of cell development
1.55 6.77e-03 GO:0040012 regulation of locomotion
1.54 2.68e-05 GO:0032583 regulation of gene-specific transcription
1.54 4.77e-05 GO:0007409 axonogenesis
1.54 8.18e-03 GO:0051270 regulation of cellular component movement

Gene overrepresentation in compartment category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.24 2.74e-02 GO:0044306 neuron projection terminus
2.24 3.89e-02 GO:0043679 axon terminus
2.08 8.18e-04 GO:0033267 axon part
1.46 1.17e-02 GO:0015629 actin cytoskeleton
1.40 9.19e-03 GO:0043005 neuron projection
1.26 2.38e-02 GO:0005615 extracellular space
1.23 1.27e-06 GO:0044459 plasma membrane part
1.11 4.64e-03 GO:0071944 cell periphery
1.11 6.04e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.48 2.81e-08 GO:0043565 sequence-specific DNA binding
1.37 6.44e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 6.44e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 3.78e-06 GO:0030528 transcription regulator activity
1.33 3.42e-02 GO:0008092 cytoskeletal protein binding
1.25 1.75e-02 GO:0005102 receptor binding
1.09 6.07e-05 GO:0005515 protein binding