Motif ID: KLF12.p2

Z-value: 5.180


Transcription factors associated with KLF12.p2:

Gene SymbolEntrez IDGene Name
KLF12 11278 Kruppel-like factor 12

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
KLF12chr13_-_73605914-0.572.0e-02Click!


Activity profile for motif KLF12.p2.

activity profile for motif KLF12.p2


Sorted Z-values histogram for motif KLF12.p2

Sorted Z-values for motif KLF12.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF12.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_14121728 7.659 LPHN1
latrophilin 1
chr19_+_2200112 6.126 NM_000479
AMH
anti-Mullerian hormone
chr19_-_3928516 5.995 EEF2
eukaryotic translation elongation factor 2
chrX_+_67965517 5.621 NM_004429
EFNB1
ephrin-B1
chr16_-_66535457 5.349 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chrX_+_152454773 5.189 NM_001001344
NM_021949
ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr19_+_16005929 4.997 FLJ25328
hypothetical LOC148231
chr16_+_67697622 4.934 NM_138612
HAS3
hyaluronan synthase 3
chr16_-_66535923 4.757 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr1_+_23990228 4.729 NM_007260
LYPLA2
lysophospholipase II
chr17_+_24095135 4.719 NM_004295
TRAF4
TNF receptor-associated factor 4
chrX_+_152699616 4.702 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr2_+_232281491 4.695 PTMA
prothymosin, alpha
chr19_+_5641307 4.663 RPL36
ribosomal protein L36
chr5_+_137829065 4.643 EGR1
early growth response 1
chr17_-_1495742 4.612 NM_003693
NM_145350
NM_145352
SCARF1


scavenger receptor class F, member 1


chr19_+_5641270 4.566 NM_033643
RPL36
ribosomal protein L36
chr9_-_129752687 4.504 NM_203305
FAM102A
family with sequence similarity 102, member A
chr19_+_5641332 4.454 NM_015414
RPL36
ribosomal protein L36
chr20_+_61394982 4.322 NM_020882
COL20A1
collagen, type XX, alpha 1
chr2_+_232281470 4.243 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr11_+_1607580 4.187 NM_001001480
KRTAP5-5
keratin associated protein 5-5
chr5_+_137829077 4.174 NM_001964
EGR1
early growth response 1
chr12_+_52665196 4.161 NM_017409
HOXC10
homeobox C10
chr1_+_1256585 4.138 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr16_+_1246273 4.040 NM_012217
TPSD1
tryptase delta 1
chr16_+_31132842 4.004 NM_001008274
TRIM72
tripartite motif containing 72
chr19_+_2173415 3.965 DOT1L
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr15_-_70288071 3.964 PKM2
pyruvate kinase, muscle
chr1_+_32512298 3.936 NM_001042771
LCK
lymphocyte-specific protein tyrosine kinase
chr15_+_65904994 3.742 NM_001031807
SKOR1
SKI family transcriptional corepressor 1
chr1_+_1099145 3.666 NM_001130045
TTLL10
tubulin tyrosine ligase-like family, member 10
chr8_-_140784416 3.580 NM_016601
KCNK9
potassium channel, subfamily K, member 9
chr10_+_80672842 3.569 ZMIZ1
zinc finger, MIZ-type containing 1
chr19_-_7840806 3.472 FLJ22184
hypothetical protein FLJ22184
chr7_+_100113664 3.454 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr19_+_2427122 3.452 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr1_+_109594163 3.408 NM_001408
CELSR2
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr20_+_44070946 3.267 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr11_-_70971556 3.261 NM_001005405
KRTAP5-11
keratin associated protein 5-11
chr12_-_51233001 3.251 NM_033448
KRT71
keratin 71
chr11_+_65164767 3.192 SIPA1
signal-induced proliferation-associated 1
chr16_-_2099854 3.142 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr1_+_201541241 3.122 BTG2
BTG family, member 2
chr17_-_7036490 3.095


chr6_+_108593907 3.050 NM_003269
NR2E1
nuclear receptor subfamily 2, group E, member 1
chr1_-_1171964 3.033 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr11_+_66381451 3.032 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_31823097 2.995 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr17_+_71235324 2.994 ITGB4
integrin, beta 4
chr20_+_61337679 2.986 NM_022161
NM_139317
BIRC7

baculoviral IAP repeat containing 7

chr1_+_16247870 2.985 NM_001165945
CLCNKB
chloride channel Kb
chr3_-_12916547 2.969 IQSEC1
IQ motif and Sec7 domain 1
chrX_+_46967360 2.911 NM_001170460
CDK16
cyclin-dependent kinase 16
chr11_+_65164963 2.905


chr2_+_104837004 2.876


chr8_-_6407882 2.868 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr9_-_138378061 2.865 NM_001080849
DNLZ
DNL-type zinc finger
chr11_+_118259684 2.848 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr9_+_139255519 2.844 NM_006088
TUBB2C
tubulin, beta 2C
chr10_+_104394185 2.807 NM_030912
TRIM8
tripartite motif containing 8
chr16_+_2959342 2.766 NM_152341
PAQR4
progestin and adipoQ receptor family member IV
chr17_-_76064842 2.751 NM_002522
NPTX1
neuronal pentraxin I
chr16_+_30583599 2.741 FBRS
fibrosin
chr9_+_138367329 2.740 NM_001145639
GPSM1
G-protein signaling modulator 1
chr16_+_2959362 2.729 PAQR4
progestin and adipoQ receptor family member IV
chr4_+_2031036 2.679 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr1_+_201541269 2.659 NM_006763
BTG2
BTG family, member 2
chr6_+_29799182 2.577 HLA-F
major histocompatibility complex, class I, F
chr19_+_1892157 2.576 NM_001319
CSNK1G2
casein kinase 1, gamma 2
chr22_+_18499354 2.560 NM_001185024
NM_013373
ZDHHC8

zinc finger, DHHC-type containing 8

chr8_-_29262240 2.559 NM_057158
DUSP4
dual specificity phosphatase 4
chr12_+_111980044 2.558 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr11_-_1464386 2.555 NM_001172223
MOB2
Mps one binder kinase activator-like 2
chr8_+_143758875 2.525 NM_005672
PSCA
prostate stem cell antigen
chr15_-_68128924 2.500 TLE3
transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)
chrX_+_151837064 2.487 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr1_+_48460943 2.473 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr1_-_1840564 2.463 NM_178545
TMEM52
transmembrane protein 52
chr8_-_145609737 2.448 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr3_-_130761967 2.400 PLXND1
plexin D1
chr9_+_34642125 2.382 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr11_-_1731273 2.373


chr11_+_63876924 2.372 CCDC88B
coiled-coil domain containing 88B
chr11_-_1576057 2.365 NM_001004325
KRTAP5-2
keratin associated protein 5-2
chr9_+_139292094 2.359 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr1_+_968522 2.356 AGRN
agrin
chr14_+_103675194 2.350 KIF26A
kinesin family member 26A
chr19_-_55912006 2.348 NM_016148
SHANK1
SH3 and multiple ankyrin repeat domains 1
chr11_+_63864263 2.345 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr6_+_37030186 2.342 NM_153370
PI16
peptidase inhibitor 16
chr17_-_77092569 2.318 ACTG1
actin, gamma 1
chr19_+_590878 2.303 NM_020637
FGF22
fibroblast growth factor 22
chr16_+_1062756 2.297 NM_001172560
SSTR5
somatostatin receptor 5
chrX_+_69581429 2.277 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr11_-_2108035 2.268 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_71141108 2.246 NM_001162995
LOC643008
hypothetical protein LOC643008
chr16_+_30583278 2.234 NM_001105079
FBRS
fibrosin
chr1_-_201321711 2.225 MYOG
myogenin (myogenic factor 4)
chr2_+_241279934 2.219 NM_198998
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr19_-_41034734 2.213 NM_004646
NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
chr17_+_7125702 2.204 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr1_-_201321999 2.200 NM_002479
MYOG
myogenin (myogenic factor 4)
chr16_+_751050 2.200 NM_013404
MSLN
mesothelin
chr17_-_1029758 2.191 NM_021962
ABR
active BCR-related gene
chr19_-_50975121 2.190


chr9_+_139006663 2.189 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr8_-_145119627 2.188 NM_201378
PLEC
plectin
chr1_-_232810111 2.175 IRF2BP2
interferon regulatory factor 2 binding protein 2
chr1_+_44643513 2.172 NM_018150
RNF220
ring finger protein 220
chr17_-_1342700 2.171 NM_001080779
MYO1C
myosin IC
chr16_+_2959467 2.164 PAQR4
progestin and adipoQ receptor family member IV
chr17_-_40839082 2.153 NM_001159330
ARHGAP27
Rho GTPase activating protein 27
chr6_+_160462852 2.140 NM_003057
NM_153187
SLC22A1

solute carrier family 22 (organic cation transporter), member 1

chr19_+_38389799 2.108 LRP3
low density lipoprotein receptor-related protein 3
chr17_-_34084682 2.074 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr9_-_129573330 2.067 NM_005489
SH2D3C
SH2 domain containing 3C
chr16_+_162845 2.062 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr22_+_29817218 2.052 SMTN
smoothelin
chr17_+_35075124 2.045 NM_003673
TCAP
titin-cap (telethonin)
chr1_+_945472 2.043 AGRN
agrin
chr7_+_27248688 2.024 NM_001989
EVX1
even-skipped homeobox 1
chr9_+_132002692 2.016 NM_001128826
NCS1
neuronal calcium sensor 1
chr11_-_117589283 2.015 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr9_-_139027435 2.014 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_50963942 2.009


chr16_+_2503915 2.004 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_-_77092831 1.999 ACTG1
actin, gamma 1
chr11_-_1006736 1.995 MUC6
mucin 6, oligomeric mucus/gel-forming
chr21_+_44530148 1.979 NM_000383
AIRE
autoimmune regulator
chr19_+_5865192 1.966 NM_004058
NM_080590
CAPS

calcyphosine

chr17_-_78391178 1.954 NM_024702
ZNF750
zinc finger protein 750
chr8_+_21956335 1.947 NM_003867
FGF17
fibroblast growth factor 17
chr17_-_35331435 1.940 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr11_-_118716244 1.939 MFRP
membrane frizzled-related protein
chr17_-_45617899 1.933 COL1A1
collagen, type I, alpha 1
chr11_+_64737886 1.932 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr1_-_199348316 1.931 NM_000069
CACNA1S
calcium channel, voltage-dependent, L type, alpha 1S subunit
chr19_+_50963484 1.928


chrX_-_106033202 1.928 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr6_+_31706345 1.926 PRRC2A
proline-rich coiled-coil 2A
chr19_-_3928840 1.922 EEF2
eukaryotic translation elongation factor 2
chr19_-_2668272 1.919 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr15_+_39573363 1.909 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr1_-_46789473 1.902 NM_001097611
KNCN
kinocilin
chr1_+_203106600 1.901 NFASC
neurofascin
chr22_+_29817315 1.898 SMTN
smoothelin
chr15_-_75694674 1.896 LINGO1
leucine rich repeat and Ig domain containing 1
chr13_-_78075683 1.895 NM_006237
POU4F1
POU class 4 homeobox 1
chr17_+_77925441 1.893 NM_018949
UTS2R
urotensin 2 receptor
chr8_-_142446546 1.891 NM_005293
GPR20
G protein-coupled receptor 20
chr11_+_60448487 1.886 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chr20_+_29598848 1.878 HM13
histocompatibility (minor) 13
chr5_+_149717489 1.877 TCOF1
Treacher Collins-Franceschetti syndrome 1
chr7_+_100111712 1.876 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_+_157441824 1.873 NM_001122951
DARC
Duffy blood group, chemokine receptor
chr8_-_145097031 1.867 NM_201380
PLEC
plectin
chr11_-_1599900 1.860 NM_001012709
KRTAP5-4
keratin associated protein 5-4
chr9_+_138991775 1.858 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr17_+_19255083 1.853 NM_007148
RNF112
ring finger protein 112
chr19_+_10689772 1.851 DNM2
dynamin 2
chr16_+_1299361 1.844 NM_194260
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr10_+_88404285 1.843 NM_001030015
NM_033282
OPN4

opsin 4

chr1_-_37991160 1.842 EPHA10
EPH receptor A10
chr1_+_891739 1.835 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr9_+_139255559 1.824 TUBB2C
tubulin, beta 2C
chr17_+_4743645 1.824 NM_001145536
C17orf107
chromosome 17 open reading frame 107
chr17_+_45617676 1.819


chr16_+_1299180 1.819 NM_194261
UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr14_+_104238713 1.818 INF2
inverted formin, FH2 and WH2 domain containing
chr10_+_80740584 1.799 ZMIZ1
zinc finger, MIZ-type containing 1
chr6_+_41714171 1.793 NM_005586
MDFI
MyoD family inhibitor
chr17_-_32368033 1.791


chr17_-_975809 1.783 ABR
active BCR-related gene
chr2_+_220017617 1.776 SPEG
SPEG complex locus
chr9_+_130124566 1.774 NM_016035
COQ4
coenzyme Q4 homolog (S. cerevisiae)
chr19_+_54883732 1.767 NM_001101340
C19orf76
chromosome 19 open reading frame 76
chr9_+_139255563 1.759 TUBB2C
tubulin, beta 2C
chr5_+_159276317 1.756 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr20_-_3713509 1.752 CENPB
centromere protein B, 80kDa
chr9_+_138991835 1.747 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr6_+_31838751 1.745 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr5_+_139719970 1.723 NM_031467
SLC4A9
solute carrier family 4, sodium bicarbonate cotransporter, member 9
chr17_-_45620911 1.720 COL1A1
collagen, type I, alpha 1
chr9_-_116920232 1.713 NM_002160
TNC
tenascin C
chr5_+_149717394 1.712 NM_000356
NM_001008657
NM_001135243
NM_001135244
NM_001135245
NM_001195141
TCOF1





Treacher Collins-Franceschetti syndrome 1





chr8_+_37672427 1.712 NM_025069
ZNF703
zinc finger protein 703
chr15_+_72397934 1.699 NM_182791
CCDC33
coiled-coil domain containing 33
chr10_+_112247614 1.699 NM_004419
DUSP5
dual specificity phosphatase 5
chr19_+_1236766 1.697 NM_001405
EFNA2
ephrin-A2
chr19_-_46504831 1.696


chr5_+_139040242 1.688 CXXC5
CXXC finger protein 5
chr9_+_136673534 1.681 COL5A1
collagen, type V, alpha 1
chr9_-_138387903 1.678 CARD9
caspase recruitment domain family, member 9
chr8_+_1940282 1.678 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr20_+_62266217 1.677 MYT1
myelin transcription factor 1
chr16_+_1299693 1.673 UBE2I
ubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)
chr16_+_84204424 1.671 NM_014615
KIAA0182
KIAA0182
chr3_-_13359746 1.668 NUP210
nucleoporin 210kDa
chr10_-_103525646 1.664 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)




Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.27 1.76e-15 GO:0007275 multicellular organismal development
1.27 7.22e-14 GO:0048856 anatomical structure development
1.29 1.22e-13 GO:0048731 system development
1.24 1.50e-13 GO:0032502 developmental process
1.30 1.19e-09 GO:0030154 cell differentiation
1.35 1.65e-09 GO:0009653 anatomical structure morphogenesis
1.12 4.98e-09 GO:0065007 biological regulation
1.28 5.20e-09 GO:0048869 cellular developmental process
1.24 1.25e-08 GO:0048518 positive regulation of biological process
1.34 2.45e-08 GO:0007399 nervous system development
1.19 5.14e-08 GO:0023052 signaling
1.35 1.78e-07 GO:0051239 regulation of multicellular organismal process
1.40 3.86e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.41 4.70e-07 GO:0022008 neurogenesis
1.27 5.71e-07 GO:0048513 organ development
1.11 5.77e-07 GO:0050789 regulation of biological process
1.11 1.19e-06 GO:0050794 regulation of cellular process
1.41 1.27e-06 GO:0048699 generation of neurons
1.27 1.83e-06 GO:0007166 cell surface receptor linked signaling pathway
1.22 3.21e-06 GO:0048522 positive regulation of cellular process
1.39 3.99e-06 GO:0050793 regulation of developmental process
1.24 6.34e-06 GO:0065008 regulation of biological quality
1.53 6.48e-06 GO:0000904 cell morphogenesis involved in differentiation
1.44 6.69e-06 GO:0030182 neuron differentiation
1.38 7.12e-06 GO:0048468 cell development
1.13 8.75e-06 GO:0032501 multicellular organismal process
1.18 1.22e-05 GO:0007165 signal transduction
1.41 1.91e-05 GO:2000026 regulation of multicellular organismal development
1.36 1.92e-05 GO:0042127 regulation of cell proliferation
1.54 2.68e-05 GO:0032583 regulation of gene-specific transcription
1.22 2.80e-05 GO:0048519 negative regulation of biological process
1.06 3.63e-05 GO:0009987 cellular process
1.45 3.95e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.54 4.77e-05 GO:0007409 axonogenesis
1.45 5.14e-05 GO:0009887 organ morphogenesis
1.42 5.47e-05 GO:0010628 positive regulation of gene expression
1.98 6.42e-05 GO:0048705 skeletal system morphogenesis
1.44 6.91e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 7.69e-05 GO:0048583 regulation of response to stimulus
1.52 9.47e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.46 9.52e-05 GO:0051253 negative regulation of RNA metabolic process
1.51 9.66e-05 GO:0048812 neuron projection morphogenesis
1.41 9.72e-05 GO:0045595 regulation of cell differentiation
1.22 1.31e-04 GO:0048523 negative regulation of cellular process
1.59 1.76e-04 GO:0007411 axon guidance
1.46 1.99e-04 GO:0008284 positive regulation of cell proliferation
1.43 2.05e-04 GO:0010629 negative regulation of gene expression
1.59 2.36e-04 GO:0001501 skeletal system development
1.33 2.76e-04 GO:0032879 regulation of localization
1.55 3.15e-04 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.45 3.17e-04 GO:0045892 negative regulation of transcription, DNA-dependent
1.24 3.79e-04 GO:0023051 regulation of signaling
1.26 4.55e-04 GO:0009966 regulation of signal transduction
1.46 5.77e-04 GO:0031175 neuron projection development
1.40 6.50e-04 GO:0032989 cellular component morphogenesis
1.46 7.44e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.41 9.07e-04 GO:0000902 cell morphogenesis
2.70 9.15e-04 GO:0060349 bone morphogenesis
1.38 9.99e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.35 1.27e-03 GO:0007267 cell-cell signaling
2.43 1.30e-03 GO:0060348 bone development
1.37 1.31e-03 GO:0009890 negative regulation of biosynthetic process
1.44 1.35e-03 GO:0048858 cell projection morphogenesis
1.55 1.46e-03 GO:0060284 regulation of cell development
1.17 2.40e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 2.45e-03 GO:0032990 cell part morphogenesis
1.32 2.53e-03 GO:0040011 locomotion
1.38 2.76e-03 GO:0048878 chemical homeostasis
1.42 2.83e-03 GO:0007417 central nervous system development
1.71 3.39e-03 GO:0003012 muscle system process
1.15 3.44e-03 GO:0016043 cellular component organization
1.29 3.78e-03 GO:0007154 cell communication
1.26 3.96e-03 GO:0009893 positive regulation of metabolic process
1.59 3.96e-03 GO:0045596 negative regulation of cell differentiation
1.16 4.24e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.39 4.38e-03 GO:0048666 neuron development
1.33 4.46e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.52 4.50e-03 GO:0051093 negative regulation of developmental process
1.33 5.13e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.97 5.17e-03 GO:0030278 regulation of ossification
1.31 5.91e-03 GO:0042592 homeostatic process
1.28 6.29e-03 GO:0010646 regulation of cell communication
1.37 6.52e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.41 6.68e-03 GO:0006935 chemotaxis
1.41 6.68e-03 GO:0042330 taxis
1.55 6.77e-03 GO:0040012 regulation of locomotion
1.39 7.20e-03 GO:0007186 G-protein coupled receptor protein signaling pathway
1.37 7.39e-03 GO:0045893 positive regulation of transcription, DNA-dependent
1.50 7.81e-03 GO:0044057 regulation of system process
1.35 8.06e-03 GO:0051254 positive regulation of RNA metabolic process
1.14 8.07e-03 GO:0080090 regulation of primary metabolic process
1.54 8.18e-03 GO:0051270 regulation of cellular component movement
1.26 9.16e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.28 9.46e-03 GO:0009605 response to external stimulus
1.83 9.46e-03 GO:0010959 regulation of metal ion transport
1.13 9.64e-03 GO:0019222 regulation of metabolic process
1.30 1.02e-02 GO:0009888 tissue development
1.33 1.08e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.14 1.13e-02 GO:0051179 localization
1.13 1.20e-02 GO:0031323 regulation of cellular metabolic process
1.34 1.38e-02 GO:0009790 embryo development
1.42 1.46e-02 GO:0051094 positive regulation of developmental process
1.35 1.48e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.78 1.59e-02 GO:0001503 ossification
1.15 1.63e-02 GO:0051234 establishment of localization
1.34 1.67e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.44 1.76e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.56 1.77e-02 GO:0003014 renal system process
1.16 1.84e-02 GO:0071842 cellular component organization at cellular level
1.47 2.15e-02 GO:0007389 pattern specification process
1.51 2.21e-02 GO:0030029 actin filament-based process
1.38 2.53e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.24 2.59e-02 GO:0031325 positive regulation of cellular metabolic process
1.17 2.64e-02 GO:0051252 regulation of RNA metabolic process
1.62 2.68e-02 GO:0007517 muscle organ development
2.00 2.74e-02 GO:0021953 central nervous system neuron differentiation
1.13 2.88e-02 GO:0071840 cellular component organization or biogenesis
1.52 3.04e-02 GO:0051960 regulation of nervous system development
1.52 3.04e-02 GO:0061061 muscle structure development
1.14 3.09e-02 GO:0006810 transport
1.37 3.32e-02 GO:0010647 positive regulation of cell communication
1.29 3.42e-02 GO:0009891 positive regulation of biosynthetic process
2.22 3.50e-02 GO:0045667 regulation of osteoblast differentiation
1.17 3.59e-02 GO:0042221 response to chemical stimulus
1.29 3.93e-02 GO:0055085 transmembrane transport
1.29 3.96e-02 GO:0048584 positive regulation of response to stimulus
1.44 4.01e-02 GO:0007420 brain development
1.38 4.01e-02 GO:0001775 cell activation
1.15 4.24e-02 GO:0010468 regulation of gene expression
1.36 4.85e-02 GO:0023056 positive regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 1.27e-06 GO:0044459 plasma membrane part
2.08 8.18e-04 GO:0033267 axon part
1.11 4.64e-03 GO:0071944 cell periphery
1.11 6.04e-03 GO:0005886 plasma membrane
1.40 9.19e-03 GO:0043005 neuron projection
1.46 1.17e-02 GO:0015629 actin cytoskeleton
1.26 2.38e-02 GO:0005615 extracellular space
2.24 2.74e-02 GO:0044306 neuron projection terminus
2.24 3.89e-02 GO:0043679 axon terminus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.48 2.81e-08 GO:0043565 sequence-specific DNA binding
1.37 6.44e-07 GO:0001071 nucleic acid binding transcription factor activity
1.37 6.44e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.34 3.78e-06 GO:0030528 transcription regulator activity
1.09 6.07e-05 GO:0005515 protein binding
1.25 1.75e-02 GO:0005102 receptor binding
1.33 3.42e-02 GO:0008092 cytoskeletal protein binding