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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: ATF4.p2

Z-value: 1.213

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_1892157	2.283	NM_001319	CSNK1G2	casein kinase 1, gamma 2
chr19_+_1892184	2.212		CSNK1G2	casein kinase 1, gamma 2
chr20_+_33667160	1.716	NM_003116	SPAG4	sperm associated antigen 4
chr6_+_26312758	1.577	NM_003545	HIST1H4E	histone cluster 1, H4e
chr17_+_38831874	1.440	NM_001661	ARL4D	ADP-ribosylation factor-like 4D
chr22_+_20101661	1.432	NM_015094	HIC2	hypermethylated in cancer 2
chr3_+_38181972	1.258	NM_005109	OXSR1	oxidative-stress responsive 1
chr16_-_3008162	1.216	NM_021195	CLDN6	claudin 6
chr1_-_243092581	1.195		HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr22_+_19601619	1.170	NM_005207	CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr19_+_16048306	1.164		TPM4	tropomyosin 4
chr22_+_36927884	1.155	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr8_+_23442331	1.146		SLC25A37	solute carrier family 25, member 37
chr8_+_98857190	1.125		LAPTM4B	lysosomal protein transmembrane 4 beta
chr4_-_8493327	1.105	NM_001101667 NM_003501	ACOX3	acyl-CoA oxidase 3, pristanoyl
chr2_+_108702338	1.101	NM_006267	RANBP2	RAN binding protein 2
chr1_+_29435534	1.100	NM_001195001 NM_005704 NM_133177 NM_133178	PTPRU	protein tyrosine phosphatase, receptor type, U
chr8_+_23442307	1.092	NM_016612	SLC25A37	solute carrier family 25, member 37
chr8_+_23442413	1.087		SLC25A37	solute carrier family 25, member 37
chr22_+_19601721	1.073		CRKL	v-crk sarcoma virus CT10 oncogene homolog (avian)-like
chr19_+_16048266	1.060		TPM4	tropomyosin 4
chr21_+_44033871	1.048		RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr19_+_16048315	1.045		TPM4	tropomyosin 4
chr1_+_210848726	1.033		ATF3	activating transcription factor 3
chr22_+_36928011	1.030		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr1_+_148090804	1.023	NM_021059 NM_001005464	HIST2H3C HIST2H3A	histone cluster 2, H3c histone cluster 2, H3a
chr1_+_210848763	1.021		ATF3	activating transcription factor 3
chr6_+_47553399	1.006	NM_012120	CD2AP	CD2-associated protein
chr1_+_210848592	0.964	NM_001040619 NM_001674	ATF3	activating transcription factor 3
chr1_+_9571518	0.950	NM_001010866 NM_001130924	TMEM201	transmembrane protein 201
chr6_+_139497933	0.917	NM_016217	HECA	headcase homolog (Drosophila)
chr5_+_56505412	0.887	NM_022913	GPBP1	GC-rich promoter binding protein 1
chr5_+_78568094	0.881
chr21_+_44033821	0.881	NM_003683	RRP1	ribosomal RNA processing 1 homolog (S. cerevisiae)
chr4_-_120595218	0.875
chr2_+_10101822	0.854	NM_001177718	KLF11	Kruppel-like factor 11
chr8_-_17148637	0.816	NM_013354 NM_054026	CNOT7	CCR4-NOT transcription complex, subunit 7
chr8_+_17148755	0.803	NM_001145152 NM_152415	VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr5_+_78567604	0.798	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr7_+_5598964	0.794		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr19_+_523568	0.789		BSG	basigin (Ok blood group)
chr16_-_14631482	0.786		PARN	poly(A)-specific ribonuclease (deadenylation nuclease)
chr5_+_56505608	0.781		GPBP1	GC-rich promoter binding protein 1
chr19_+_18529652	0.763		C19orf50	chromosome 19 open reading frame 50
chr11_+_18372682	0.757		LDHA	lactate dehydrogenase A
chr20_+_1254033	0.755		LOC100507495	hypothetical LOC100507495
chr1_-_148079357	0.754	NM_021059 NM_001005464	HIST2H3C HIST2H3A	histone cluster 2, H3c histone cluster 2, H3a
chr7_-_129379947	0.746	NM_003344 NM_182697	UBE2H	ubiquitin-conjugating enzyme E2H (UBC8 homolog, yeast)
chr11_+_18372689	0.743		LDHA	lactate dehydrogenase A
chr1_+_51855343	0.741		OSBPL9	oxysterol binding protein-like 9
chr16_-_14631595	0.741	NM_001134477 NM_002582	PARN	poly(A)-specific ribonuclease (deadenylation nuclease)
chr11_+_799918	0.740	NM_001004	RPLP2	ribosomal protein, large, P2
chr11_+_18372687	0.739		LDHA	lactate dehydrogenase A
chr20_-_33329319	0.732		EDEM2	ER degradation enhancer, mannosidase alpha-like 2
chr1_-_17318452	0.732	NM_007365	PADI2	peptidyl arginine deiminase, type II
chr16_+_2503994	0.729		ATP6V0C	ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr1_+_9522133	0.724		SLC25A33	solute carrier family 25, member 33
chr7_+_5598979	0.719	NM_003088	FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_+_55277795	0.719		PCSK9	proprotein convertase subtilisin/kexin type 9
chr2_+_170149092	0.716	NM_004792	PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr11_+_18372708	0.712		LDHA	lactate dehydrogenase A
chr19_+_54067450	0.708	NM_014330	PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr3_+_38182251	0.706		OXSR1	oxidative-stress responsive 1
chr20_+_48240772	0.703	NM_005194	CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_48240867	0.697		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr20_+_48240705	0.696		CEBPB	CCAAT/enhancer binding protein (C/EBP), beta
chr19_+_54067489	0.689		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr19_+_40183065	0.686	NM_001136199 NM_020895	GRAMD1A	GRAM domain containing 1A
chr20_+_19863716	0.682		RIN2	Ras and Rab interactor 2
chr20_+_34635362	0.681	NM_021809	TGIF2	TGFB-induced factor homeobox 2
chr6_+_44463265	0.678	NM_001253	CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr11_+_799985	0.678		RPLP2	ribosomal protein, large, P2
chr20_+_57199469	0.676	NM_178457	ZNF831	zinc finger protein 831
chr12_+_22669352	0.676		ETNK1	ethanolamine kinase 1
chr19_+_523575	0.672		BSG	basigin (Ok blood group)
chr1_+_173235193	0.672	NM_001007214	CACYBP	calcyclin binding protein
chr5_+_112877251	0.670	NM_022828	YTHDC2	YTH domain containing 2
chr19_+_54067491	0.670		PPP1R15A	protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr20_+_30161173	0.668		TM9SF4	transmembrane 9 superfamily protein member 4
chr19_+_523403	0.667	NM_001728 NM_198589	BSG	basigin (Ok blood group)
chr12_+_22669275	0.664	NM_001039481 NM_018638	ETNK1	ethanolamine kinase 1
chr10_+_71833866	0.663	NM_004096	EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2
chr16_-_85146181	0.654	NM_001159380 NM_001159377 NM_001159378 NM_001159379 NM_022764	MTHFSD	methenyltetrahydrofolate synthetase domain containing
chr7_+_140042932	0.653	NM_004546	NDUFB2	NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa
chr8_-_17148474	0.652		CNOT7	CCR4-NOT transcription complex, subunit 7
chr6_+_64339869	0.651	NM_003463	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr8_-_142446546	0.644	NM_005293	GPR20	G protein-coupled receptor 20
chr17_+_24095135	0.642	NM_004295	TRAF4	TNF receptor-associated factor 4
chr8_+_98856984	0.637	NM_018407	LAPTM4B	lysosomal protein transmembrane 4 beta
chr3_+_38182120	0.634		OXSR1	oxidative-stress responsive 1
chr10_+_71833905	0.630		EIF4EBP2	eukaryotic translation initiation factor 4E binding protein 2
chr16_-_78192111	0.626	NM_001031804 NM_005360	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)
chr16_+_79906084	0.625		GAN	gigaxonin
chr19_+_54682661	0.622		RPL13A	ribosomal protein L13a
chr2_+_10969513	0.619	NM_002236	KCNF1	potassium voltage-gated channel, subfamily F, member 1
chr20_+_43996717	0.619	NM_022104	PCIF1	PDX1 C-terminal inhibiting factor 1
chr19_+_54682676	0.614	NM_012423	RPL13A	ribosomal protein L13a
chr8_-_95343696	0.608		GEM	GTP binding protein overexpressed in skeletal muscle
chr20_-_34635091	0.607
chr12_+_70119785	0.602		LGR5	leucine-rich repeat containing G protein-coupled receptor 5
chr11_+_18372493	0.602	NM_001135239 NM_001165415 NM_001165416 NM_005566	LDHA	lactate dehydrogenase A
chr8_-_95343716	0.600	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr16_+_3273369	0.596	NM_005741	ZNF263	zinc finger protein 263
chr19_+_40183169	0.593		GRAMD1A	GRAM domain containing 1A
chr16_+_79906065	0.593	NM_022041	GAN	gigaxonin
chr16_-_4837266	0.592	NM_032569	GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr8_+_26204960	0.591		PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr16_+_29984591	0.581		ALDOA	aldolase A, fructose-bisphosphate
chr16_+_29984544	0.580	NM_184041	ALDOA	aldolase A, fructose-bisphosphate
chr1_+_114273518	0.579	NM_152696 NM_198268	HIPK1	homeodomain interacting protein kinase 1
chr17_+_22645268	0.577		WSB1	WD repeat and SOCS box containing 1
chr9_-_130683997	0.574	NM_001122671 NM_001122672 NM_004059	CCBL1	cysteine conjugate-beta lyase, cytoplasmic
chr17_-_76064842	0.568	NM_002522	NPTX1	neuronal pentraxin I
chr20_-_60151835	0.567	NM_002792	PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr2_+_170149348	0.567		PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr18_+_31963851	0.564		ELP2	elongation protein 2 homolog (S. cerevisiae)
chr16_+_29819647	0.564	NM_181718	ASPHD1	aspartate beta-hydroxylase domain containing 1
chr1_+_26368969	0.562	NM_015871	ZNF593	zinc finger protein 593
chr7_+_116447499	0.560		ST7	suppression of tumorigenicity 7
chr16_+_29984611	0.559		ALDOA	aldolase A, fructose-bisphosphate
chr9_+_130684189	0.559	NM_001127245 NM_019594	LRRC8A	leucine rich repeat containing 8 family, member A
chr14_+_54588151	0.558		MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like
chr4_+_8493396	0.554	NM_152544	METTL19	methyltransferase like 19
chr6_-_3102690	0.553	NM_001069	TUBB2A	tubulin, beta 2A
chr8_+_26204921	0.545	NM_002717	PPP2R2A	protein phosphatase 2, regulatory subunit B, alpha
chr18_+_31963879	0.542	NM_018255	ELP2	elongation protein 2 homolog (S. cerevisiae)
chr17_+_22645232	0.541	NM_015626 NM_134265	WSB1	WD repeat and SOCS box containing 1
chr16_+_54782802	0.538		GNAO1	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr14_+_54588138	0.536		MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like
chr6_+_64340408	0.527		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr9_+_130684248	0.525		LRRC8A	leucine rich repeat containing 8 family, member A
chr6_+_44463418	0.524		CDC5L	CDC5 cell division cycle 5-like (S. pombe)
chr1_+_6562681	0.522		ZBTB48	zinc finger and BTB domain containing 48
chr1_+_51474531	0.521	NM_014372	RNF11	ring finger protein 11
chr19_+_12917607	0.519	NM_005053	RAD23A	RAD23 homolog A (S. cerevisiae)
chr1_+_6562634	0.514	NM_005341	ZBTB48	zinc finger and BTB domain containing 48
chr16_+_29984647	0.511		ALDOA	aldolase A, fructose-bisphosphate
chr16_+_29984621	0.509		ALDOA	aldolase A, fructose-bisphosphate
chr7_-_127833231	0.509	NM_001142573 NM_001142574 NM_001142575	IMPDH1	IMP (inosine 5'-monophosphate) dehydrogenase 1
chr3_-_16281287	0.509	NM_001047434 NM_206831	DPH3	DPH3, KTI11 homolog (S. cerevisiae)
chr11_-_799465	0.509		LRDD	leucine-rich repeats and death domain containing
chr6_+_150112537	0.507		PCMT1	protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr7_+_107318852	0.507		DLD	dihydrolipoamide dehydrogenase
chr5_+_44844724	0.506	NM_016640	MRPS30	mitochondrial ribosomal protein S30
chr20_-_17897384	0.500	NM_152227	SNX5	sorting nexin 5
chr7_+_107318854	0.499		DLD	dihydrolipoamide dehydrogenase
chr6_-_43585958	0.499		C6orf154	chromosome 6 open reading frame 154
chr19_+_18529571	0.498	NM_001171948 NM_001171949 NM_024069	C19orf50	chromosome 19 open reading frame 50
chr19_-_10625449	0.497		LOC147727	hypothetical LOC147727
chr19_+_4353658	0.497	NM_005483	CHAF1A	chromatin assembly factor 1, subunit A (p150)
chr16_+_3273522	0.491		ZNF263	zinc finger protein 263
chr11_-_66367279	0.489
chr8_+_17824631	0.487	NM_006197	PCM1	pericentriolar material 1
chr17_+_45401560	0.486	NM_138281	DLX4	distal-less homeobox 4
chr20_+_17897529	0.484	NM_052865	C20orf72	chromosome 20 open reading frame 72
chrX_+_67635593	0.483		YIPF6	Yip1 domain family, member 6
chr8_-_11361594	0.481	NM_053279	FAM167A	family with sequence similarity 167, member A
chr19_-_8670054	0.481	NM_178525	ACTL9	actin-like 9
chr3_+_129690735	0.481
chr1_-_20916789	0.479	NM_001122819 NM_020816	KIF17	kinesin family member 17
chr3_+_125931962	0.478		UMPS	uridine monophosphate synthetase
chr1_+_11962824	0.478	NM_001127660 NM_014874	MFN2	mitofusin 2
chr17_+_45221002	0.476		MYST2	MYST histone acetyltransferase 2
chr20_+_33823318	0.473	NM_016436	PHF20	PHD finger protein 20
chr6_-_15356865	0.473
chr7_+_107318821	0.472	NM_000108	DLD	dihydrolipoamide dehydrogenase
chr20_-_60151802	0.470		PSMA7	proteasome (prosome, macropain) subunit, alpha type, 7
chr20_+_25124333	0.463	NM_001114089 NM_001247	ENTPD6	ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr14_+_23968979	0.461	NM_015299	KHNYN	KH and NYN domain containing
chr2_-_156897286	0.460	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr2_+_107809819	0.460	NM_182588	RGPD4	RANBP2-like and GRIP domain containing 4
chr1_+_149520601	0.459		ZNF687	zinc finger protein 687
chr4_+_109130491	0.458		HADH	hydroxyacyl-CoA dehydrogenase
chr14_+_54588125	0.458		MAPK1IP1L	mitogen-activated protein kinase 1 interacting protein 1-like
chr19_-_17047228	0.458	NM_001011699 NM_033417	HAUS8	HAUS augmin-like complex, subunit 8
chr6_+_64340388	0.455		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr2_+_60962279	0.454		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_-_34963565	0.451	NM_005643	TAF11	TAF11 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 28kDa
chr19_-_54231884	0.449	NM_033377	CGB1 CGB2	chorionic gonadotropin, beta polypeptide 1 chorionic gonadotropin, beta polypeptide 2
chr3_+_185536376	0.449	NM_001171093	FAM131A	family with sequence similarity 131, member A
chr4_+_1842947	0.448		WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr21_-_43903755	0.447	NM_007031	HSF2BP	heat shock transcription factor 2 binding protein
chr1_+_1994943	0.446	NM_001033581	PRKCZ	protein kinase C, zeta
chr7_+_152087753	0.446	NM_001040135 NM_020445	ACTR3B	ARP3 actin-related protein 3 homolog B (yeast)
chr8_+_17824772	0.446		PCM1	pericentriolar material 1
chr19_+_47080285	0.445	NM_199002	ARHGEF1	Rho guanine nucleotide exchange factor (GEF) 1
chr8_+_17824781	0.443		PCM1	pericentriolar material 1
chr19_+_12917656	0.443		RAD23A	RAD23 homolog A (S. cerevisiae)
chr18_+_18767275	0.442	NM_002894	RBBP8	retinoblastoma binding protein 8
chr3_+_125931902	0.441	NM_000373	UMPS	uridine monophosphate synthetase
chr1_+_55277736	0.441	NM_174936	PCSK9	proprotein convertase subtilisin/kexin type 9
chr19_+_54872220	0.440		PRMT1	protein arginine methyltransferase 1
chr6_+_30137014	0.440	NM_014596 NM_170783	ZNRD1	zinc ribbon domain containing 1
chr6_-_30631912	0.439		GNL1	guanine nucleotide binding protein-like 1
chr6_+_31016755	0.439	NM_080870	DPCR1	diffuse panbronchiolitis critical region 1
chr6_-_31882558	0.436		LSM2	LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_+_17824790	0.435		PCM1	pericentriolar material 1
chr19_+_16048047	0.432	NM_003290	TPM4	tropomyosin 4
chr17_+_45221060	0.432	NM_007067	MYST2	MYST histone acetyltransferase 2
chr2_+_131579334	0.431		PLEKHB2	pleckstrin homology domain containing, family B (evectins) member 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.54	8.12e-10	GO:0034641	cellular nitrogen compound metabolic process
1.60	9.14e-10	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33	1.99e-09	GO:0044237	cellular metabolic process
1.52	3.19e-09	GO:0006807	nitrogen compound metabolic process
1.42	4.79e-09	GO:0044260	cellular macromolecule metabolic process
1.38	5.07e-09	GO:0043170	macromolecule metabolic process
1.28	1.48e-08	GO:0008152	metabolic process
1.31	1.62e-08	GO:0044238	primary metabolic process
1.16	6.62e-08	GO:0009987	cellular process
1.57	1.79e-06	GO:0090304	nucleic acid metabolic process
1.58	4.32e-05	GO:0010467	gene expression
1.52	2.11e-03	GO:0016070	RNA metabolic process
1.41	3.16e-03	GO:0044249	cellular biosynthetic process
1.63	3.99e-03	GO:0044248	cellular catabolic process
1.51	4.50e-03	GO:0034645	cellular macromolecule biosynthetic process
1.50	4.92e-03	GO:0009059	macromolecule biosynthetic process
1.51	6.70e-03	GO:0006996	organelle organization
1.31	1.04e-02	GO:0071840	cellular component organization or biogenesis
1.38	1.19e-02	GO:0009058	biosynthetic process
1.84	1.50e-02	GO:0051276	chromosome organization
1.52	1.68e-02	GO:0009056	catabolic process
18.51	1.68e-02	GO:0070584	mitochondrion morphogenesis
1.97	1.85e-02	GO:0006325	chromatin organization
2.16	2.37e-02	GO:0009259	ribonucleotide metabolic process
2.17	2.62e-02	GO:0009150	purine ribonucleotide metabolic process
2.84	2.85e-02	GO:0006333	chromatin assembly or disassembly
2.98	3.54e-02	GO:0050657	nucleic acid transport
2.98	3.54e-02	GO:0050658	RNA transport
2.98	3.54e-02	GO:0051236	establishment of RNA localization
1.98	3.89e-02	GO:0072521	purine-containing compound metabolic process
1.29	4.57e-02	GO:0016043	cellular component organization
1.88	4.57e-02	GO:0006753	nucleoside phosphate metabolic process
1.88	4.57e-02	GO:0009117	nucleotide metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	1.56e-13	GO:0043231	intracellular membrane-bounded organelle
1.26	2.05e-13	GO:0043227	membrane-bounded organelle
1.19	2.21e-13	GO:0044424	intracellular part
1.18	1.08e-12	GO:0005622	intracellular
1.39	2.42e-12	GO:0044446	intracellular organelle part
1.38	5.18e-12	GO:0044422	organelle part
1.21	4.31e-11	GO:0043229	intracellular organelle
1.69	5.56e-11	GO:0044428	nuclear part
1.21	6.65e-11	GO:0043226	organelle
1.73	7.26e-10	GO:0031981	nuclear lumen
1.64	8.55e-10	GO:0070013	intracellular organelle lumen
1.62	2.68e-09	GO:0043233	organelle lumen
1.61	3.29e-09	GO:0031974	membrane-enclosed lumen
1.33	1.17e-08	GO:0005634	nucleus
1.70	5.59e-06	GO:0005654	nucleoplasm
1.17	1.56e-04	GO:0005737	cytoplasm
1.96	4.02e-04	GO:0005694	chromosome
1.97	1.09e-03	GO:0005730	nucleolus
1.96	2.93e-03	GO:0044427	chromosomal part
1.33	6.21e-03	GO:0043228	non-membrane-bounded organelle
1.33	6.21e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.19	6.81e-03	GO:0044444	cytoplasmic part
1.36	2.44e-02	GO:0031090	organelle membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.28	6.23e-10	GO:0005515	protein binding
1.15	4.61e-09	GO:0005488	binding
1.54	3.76e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.47	5.15e-05	GO:0000166	nucleotide binding
1.51	1.03e-04	GO:0032553	ribonucleotide binding
1.51	1.03e-04	GO:0032555	purine ribonucleotide binding
1.50	1.44e-04	GO:0017076	purine nucleotide binding
1.83	2.84e-04	GO:0017111	nucleoside-triphosphatase activity
1.79	5.57e-04	GO:0016462	pyrophosphatase activity
1.33	6.30e-04	GO:0003676	nucleic acid binding
1.78	6.46e-04	GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.78	7.48e-04	GO:0016817	hydrolase activity, acting on acid anhydrides
1.23	1.60e-03	GO:0003824	catalytic activity
1.51	2.23e-03	GO:0005524	ATP binding
1.50	2.78e-03	GO:0032559	adenyl ribonucleotide binding
1.49	3.59e-03	GO:0030554	adenyl nucleotide binding
2.40	1.10e-02	GO:0003924	GTPase activity