Motif ID: PAX2.p2

Z-value: 1.204


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX2chr10_+_102495327-0.712.0e-03Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_9126742 2.110 NM_001083625
NM_015208
 ANKRD12

ankyrin repeat domain 12

chr6_+_127629677 1.607 NM_030963
 RNF146
ring finger protein 146
chr5_-_133734616 1.454 CDKL3
cyclin-dependent kinase-like 3
chr5_+_133734768 1.405 NM_003337
 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr15_+_41597097 0.901 NM_002373
 MAP1A
microtubule-associated protein 1A
chr17_+_55052060 0.894 CLTC
clathrin, heavy chain (Hc)
chr17_+_55051818 0.890 NM_004859
 CLTC
clathrin, heavy chain (Hc)
chr2_+_46779827 0.890 NM_144949
 SOCS5
suppressor of cytokine signaling 5
chr6_+_89847019 0.878 NM_006813
 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_87921980 0.876 NM_015021
 ZNF292
zinc finger protein 292
chr6_+_89847183 0.875 PNRC1
proline-rich nuclear receptor coactivator 1
chr18_+_30875297 0.869 NM_014268
 MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr15_+_41871809 0.845 SERF2-C15ORF63
SERF2
SERF2-C15orf63 read-through transcript
small EDRK-rich factor 2
chr20_+_46971618 0.843 NM_006420
 ARFGEF2
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr17_+_55052046 0.838 CLTC
clathrin, heavy chain (Hc)
chr3_+_19963534 0.819 NM_004162
 RAB5A
RAB5A, member RAS oncogene family
chr15_+_41871768 0.816 NM_001018108
 SERF2
small EDRK-rich factor 2
chr1_-_152459697 0.795 NM_001098616
NM_015449
NM_138740
 C1orf43


chromosome 1 open reading frame 43


chr2_+_46779553 0.791 NM_014011
 SOCS5
suppressor of cytokine signaling 5
chr17_+_55052065 0.785 CLTC
clathrin, heavy chain (Hc)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
1.90 3.61e-02 GO:0006913 nucleocytoplasmic transport
1.61 4.59e-02 GO:0044419 interspecies interaction between organisms
1.47 1.84e-03 GO:0046907 intracellular transport
1.39 2.96e-02 GO:0008219 cell death
1.39 3.95e-02 GO:0016265 death
1.34 4.13e-03 GO:0033036 macromolecule localization
1.32 2.89e-02 GO:0051641 cellular localization
1.29 6.08e-03 GO:0016070 RNA metabolic process
1.27 9.40e-04 GO:0090304 nucleic acid metabolic process
1.27 1.49e-02 GO:0010467 gene expression
1.22 5.17e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 5.08e-03 GO:0044260 cellular macromolecule metabolic process
1.16 3.00e-03 GO:0043170 macromolecule metabolic process
1.08 1.07e-03 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.34 5.25e-04 GO:0005654 nucleoplasm
1.26 3.01e-04 GO:0044428 nuclear part
1.24 5.00e-03 GO:0005829 cytosol
1.23 3.12e-02 GO:0031981 nuclear lumen
1.21 8.90e-04 GO:0043234 protein complex
1.20 2.62e-04 GO:0032991 macromolecular complex
1.20 3.68e-02 GO:0043233 organelle lumen
1.16 3.21e-05 GO:0044422 organelle part
1.15 6.54e-05 GO:0044446 intracellular organelle part
1.15 1.54e-04 GO:0005634 nucleus
1.14 5.93e-09 GO:0005737 cytoplasm
1.13 1.29e-03 GO:0044444 cytoplasmic part
1.11 6.49e-11 GO:0044424 intracellular part
1.11 3.29e-07 GO:0043229 intracellular organelle
1.11 4.66e-07 GO:0043226 organelle
1.11 6.37e-06 GO:0043231 intracellular membrane-bounded organelle
1.11 8.82e-06 GO:0043227 membrane-bounded organelle
1.10 3.99e-10 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
2.61 3.73e-02 GO:0003707 steroid hormone receptor activity
2.59 2.61e-02 GO:0004879 ligand-dependent nuclear receptor activity
1.77 1.25e-02 GO:0003713 transcription coactivator activity
1.66 8.44e-04 GO:0000988 protein binding transcription factor activity
1.66 8.44e-04 GO:0000989 transcription factor binding transcription factor activity
1.65 1.43e-03 GO:0003712 transcription cofactor activity
1.17 9.12e-11 GO:0005515 protein binding
1.07 8.86e-04 GO:0005488 binding