Motif ID: SMAD1..7,9.p2

Z-value: 4.325


Transcription factors associated with SMAD1..7,9.p2:

Gene SymbolEntrez IDGene Name
SMAD1 4086 SMAD family member 1
SMAD2 4087 SMAD family member 2
SMAD3 4088 SMAD family member 3
SMAD4 4089 SMAD family member 4
SMAD5 4090 SMAD family member 5
SMAD6 4091 SMAD family member 6
SMAD7 4092 SMAD family member 7
SMAD9 4093 SMAD family member 9

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SMAD4chr18_+_46810598-0.721.7e-03Click!
SMAD5chr5_+_135496421-0.702.3e-03Click!
SMAD1chr4_+_146623405-0.621.0e-02Click!
SMAD3chr15_+_652455460.523.9e-02Click!
SMAD7chr18_-_447297000.514.4e-02Click!
SMAD6chr15_+_647817230.361.7e-01Click!
SMAD2chr18_-_43711452-0.351.8e-01Click!
SMAD9chr13_-_363923700.302.5e-01Click!


Activity profile for motif SMAD1..7,9.p2.

activity profile for motif SMAD1..7,9.p2


Sorted Z-values histogram for motif SMAD1..7,9.p2

Sorted Z-values for motif SMAD1..7,9.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SMAD1..7,9.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_135343649 7.054 NM_012147
DUX2
double homeobox 2
chr10_+_135333667 7.004 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191239247 6.665 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191226073 6.296 NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr10_+_135330357 6.228 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191232653 5.968 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191235959 5.914 NM_001177376
DUX4L4
double homeobox 4 like 4
chrX_+_110226030 5.303 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr16_+_56219802 5.072 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr11_+_47564805 4.961 NM_001164379
FAM180B
family with sequence similarity 180, member B
chr4_+_191229360 4.837 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr9_-_139183675 4.515


chr10_-_102880892 4.513 NM_001085398
TLX1NB
TLX1 neighbor
chrX_+_152682772 4.504 NM_001163257
NM_005393
PLXNB3

plexin B3

chr4_+_191242540 4.333 NM_033178
NM_012147
NM_001177376
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr19_+_2200112 4.241 NM_000479
AMH
anti-Mullerian hormone
chr17_+_19377732 4.221 NM_018242
SLC47A1
solute carrier family 47, member 1
chr12_+_55896844 4.094 NM_007224
NXPH4
neurexophilin 4
chr1_+_15145001 4.081 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr8_+_143542378 3.934 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr19_-_1989937 3.880 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr22_-_22970850 3.843 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr20_+_55399847 3.805 NM_017495
NM_183425
RBM38

RNA binding motif protein 38

chr1_+_8928508 3.792 NM_001215
CA6
carbonic anhydrase VI
chr20_-_61669550 3.573 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chrX_+_152823722 3.487 NM_000054
NM_001146151
AVPR2

arginine vasopressin receptor 2

chrX_+_135441970 3.453 NM_016267
VGLL1
vestigial like 1 (Drosophila)
chr7_-_150283794 3.399 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr8_-_143864933 3.394 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr19_-_53808505 3.370 NM_017708
FAM83E
family with sequence similarity 83, member E
chr1_-_6368324 3.361 NM_181864
ACOT7
acyl-CoA thioesterase 7
chr16_+_87232501 3.211 NM_013278
IL17C
interleukin 17C
chr21_+_44844924 3.129 NM_198689
KRTAP10-7
keratin associated protein 10-7
chr14_+_99273751 3.120 EML1
echinoderm microtubule associated protein like 1
chr11_+_63864263 3.116 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr1_+_968522 3.110 AGRN
agrin
chr11_+_303852 3.101 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr8_+_144522389 3.085 NM_052924
RHPN1
rhophilin, Rho GTPase binding protein 1
chr22_+_23221114 3.083 NM_016327
UPB1
ureidopropionase, beta
chr1_-_35795589 3.059 KIAA0319L
KIAA0319-like
chr19_+_60691733 2.996 SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr11_+_113351006 2.986 NM_000869
NM_213621
HTR3A

5-hydroxytryptamine (serotonin) receptor 3A

chr17_-_1342700 2.975 NM_001080779
MYO1C
myosin IC
chrX_-_102870207 2.974 NM_001024452
NM_001172285
GLRA4

glycine receptor, alpha 4

chr14_+_105012106 2.956 NM_001312
CRIP2
cysteine-rich protein 2
chr11_+_74548472 2.931 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr19_-_54857003 2.922 IRF3
interferon regulatory factor 3
chr1_-_35795525 2.910 KIAA0319L
KIAA0319-like
chr1_-_35795592 2.891 NM_024874
KIAA0319L
KIAA0319-like
chrX_-_131923092 2.866 NM_001077188
NM_147175
HS6ST2

heparan sulfate 6-O-sulfotransferase 2

chr9_-_91284430 2.789 NM_001142287
NM_006378
SEMA4D

sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

chr1_-_1840564 2.783 NM_178545
TMEM52
transmembrane protein 52
chr7_+_75977680 2.755 NM_030570
NM_182684
UPK3B

uroplakin 3B

chrX_+_79164397 2.750 NM_016954
TBX22
T-box 22
chr3_-_48573556 2.749 PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr8_+_22465368 2.708 SORBS3
sorbin and SH3 domain containing 3
chr9_+_123369219 2.655 NM_032552
DAB2IP
DAB2 interacting protein
chr8_+_128817658 2.651 MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chr10_+_102881050 2.628 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr16_+_2138688 2.606 RAB26
RAB26, member RAS oncogene family
chr3_-_48576204 2.603 NM_033199
UCN2
urocortin 2
chr11_-_2136129 2.593


chr9_+_133154896 2.592 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr19_+_10392128 2.577 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr17_-_24357014 2.561 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr7_+_1543644 2.542 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr11_-_116199145 2.539 NM_000482
APOA4
apolipoprotein A-IV
chr11_+_1420250 2.526 BRSK2
BR serine/threonine kinase 2
chr1_+_9571518 2.441 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr9_-_138387903 2.422 CARD9
caspase recruitment domain family, member 9
chr1_+_178466064 2.410 NM_033343
LHX4
LIM homeobox 4
chr11_-_60475558 2.389 NM_016582
SLC15A3
solute carrier family 15, member 3
chr12_+_48641545 2.382 NM_001651
AQP5
aquaporin 5
chr17_-_17421050 2.367 PEMT
phosphatidylethanolamine N-methyltransferase
chr21_+_44818033 2.359 NM_198687
KRTAP10-4
keratin associated protein 10-4
chr6_-_32121784 2.354 NM_032470
TNXB
tenascin XB
chr11_+_116580892 2.351 TAGLN
transgelin
chr3_+_50259329 2.340 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr15_+_39918302 2.316 NM_001114633
PLA2G4B
phospholipase A2, group IVB (cytosolic)
chr22_+_20067662 2.311 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr1_+_199426575 2.299 NM_001164586
IGFN1
immunoglobulin-like and fibronectin type III domain containing 1
chr3_-_46693902 2.297 NM_182775
ALS2CL
ALS2 C-terminal like
chr21_+_44856423 2.297 NM_198695
KRTAP10-8
keratin associated protein 10-8
chr7_-_1562272 2.292 NM_001097620
TMEM184A
transmembrane protein 184A
chr6_+_50789215 2.273 NM_172238
TFAP2D
transcription factor AP-2 delta (activating enhancer binding protein 2 delta)
chr19_-_46626474 2.272 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr16_+_2071631 2.248 TSC2
tuberous sclerosis 2
chr9_-_138772506 2.245 NM_178469
LCN8
lipocalin 8
chr19_-_47261761 2.242 NM_002088
GRIK5
glutamate receptor, ionotropic, kainate 5
chr9_-_138387926 2.208 NM_052813
NM_052814
CARD9

caspase recruitment domain family, member 9

chr1_+_100776280 2.208 NM_022049
GPR88
G protein-coupled receptor 88
chr16_+_55553262 2.207 NM_000078
CETP
cholesteryl ester transfer protein, plasma
chr17_+_12633504 2.195 NM_014859
ARHGAP44
Rho GTPase activating protein 44
chr14_-_105163301 2.186 IGHG4
immunoglobulin heavy constant gamma 4 (G4m marker)
chr21_+_43462209 2.185 NM_000394
CRYAA
crystallin, alpha A
chrX_-_135941498 2.181 NM_054021
GPR101
G protein-coupled receptor 101
chr14_+_51850754 2.179 NM_000956
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr7_-_100331417 2.163 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr8_+_142501188 2.159 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chrX_+_151837064 2.156 NM_001178113
ZNF185
zinc finger protein 185 (LIM domain)
chr17_-_23965305 2.139 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr5_+_170779664 2.138 FGF18
fibroblast growth factor 18
chr19_+_17253453 2.124 NM_152363
ANKLE1
ankyrin repeat and LEM domain containing 1
chr3_-_197103848 2.123 TNK2
tyrosine kinase, non-receptor, 2
chr9_-_139010805 2.110 NM_004669
CLIC3
chloride intracellular channel 3
chr9_+_125813672 2.109 NM_004789
LHX2
LIM homeobox 2
chr9_+_139239464 2.107 NM_199001
C9orf169
chromosome 9 open reading frame 169
chr20_-_62052922 2.090 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr17_+_71975224 2.087 NM_001088
AANAT
aralkylamine N-acetyltransferase
chr11_+_63627816 2.086 NM_013280
FLRT1
fibronectin leucine rich transmembrane protein 1
chrX_-_41667174 2.074 NM_001126054
NM_001126055
NM_003688
CASK


calcium/calmodulin-dependent serine protein kinase (MAGUK family)


chr1_-_1171964 2.065 NM_001014980
FAM132A
family with sequence similarity 132, member A
chr5_+_170779264 2.060 NM_003862
FGF18
fibroblast growth factor 18
chr3_+_42702014 2.047 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr16_-_265868 2.042 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr2_+_71016503 2.017 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr8_+_128817494 2.013 NM_002467
MYC
v-myc myelocytomatosis viral oncogene homolog (avian)
chr8_+_22493928 2.003 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr19_-_17275083 2.003 NM_024527
ABHD8
abhydrolase domain containing 8
chr21_+_44881700 2.001 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr2_-_232499202 1.994 NM_024409
NPPC
natriuretic peptide C
chrX_+_101853912 1.984 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr7_-_72761367 1.972 STX1A
syntaxin 1A (brain)
chr3_-_129689394 1.969 NM_001145662
GATA2
GATA binding protein 2
chr19_+_60691671 1.968 NM_001144950
NM_001195267
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr11_+_64737886 1.961 NM_001004326
SLC22A20
solute carrier family 22, member 20
chr7_+_27248688 1.947 NM_001989
EVX1
even-skipped homeobox 1
chr7_+_54577512 1.941 NM_182546
VSTM2A
V-set and transmembrane domain containing 2A
chr1_+_20751518 1.927 NM_207334
FAM43B
family with sequence similarity 43, member B
chr15_-_70385709 1.927 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr7_+_75947762 1.918 NM_001102596
DTX2
deltex homolog 2 (Drosophila)
chr9_+_125813849 1.914 LHX2
LIM homeobox 2
chr16_-_772926 1.904 NM_001025190
MSLNL
mesothelin-like
chr19_+_3958690 1.892 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr9_-_37455250 1.882 ZBTB5
zinc finger and BTB domain containing 5
chr19_-_5735775 1.882 NM_001134316
PRR22
proline rich 22
chr6_+_34590624 1.860 PACSIN1
protein kinase C and casein kinase substrate in neurons 1
chr19_-_41034734 1.854 NM_004646
NPHS1
nephrosis 1, congenital, Finnish type (nephrin)
chr21_+_44566063 1.844 PFKL
phosphofructokinase, liver
chr6_+_33486750 1.843 NM_002636
NM_024165
PHF1

PHD finger protein 1

chrX_+_149280486 1.837 MAMLD1
mastermind-like domain containing 1
chr9_+_135491305 1.833 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr7_+_1063666 1.832 NM_138445
GPR146
G protein-coupled receptor 146
chr22_+_36365629 1.831 NM_018957
SH3BP1
SH3-domain binding protein 1
chr3_+_185762233 1.831 NM_004443
EPHB3
EPH receptor B3
chr22_+_20068039 1.828 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr1_+_203279050 1.823 CNTN2
contactin 2 (axonal)
chr1_+_2397613 1.819 NM_014638
PLCH2
phospholipase C, eta 2
chr1_-_21868380 1.812 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr7_+_1546535 1.811 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr11_+_76455574 1.795 NM_004055
CAPN5
calpain 5
chr2_+_233112680 1.789 NM_005199
CHRNG
cholinergic receptor, nicotinic, gamma
chrX_+_100361588 1.786 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr11_-_117200618 1.783 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr4_-_1192749 1.765 NM_001199021
LOC100130872
SPON2
hypothetical LOC100130872
spondin 2, extracellular matrix protein
chr19_+_40474867 1.762 NM_002361
NM_080600
MAG

myelin associated glycoprotein

chr9_+_130056513 1.741


chrX_+_152454773 1.739 NM_001001344
NM_021949
ATP2B3

ATPase, Ca++ transporting, plasma membrane 3

chr5_+_133479196 1.715 NM_001134851
NM_201632
NM_201634
NM_213648
TCF7



transcription factor 7 (T-cell specific, HMG-box)



chr19_+_40299058 1.707 FXYD3
FXYD domain containing ion transport regulator 3
chr18_+_894943 1.698 NM_001099733
ADCYAP1
adenylate cyclase activating polypeptide 1 (pituitary)
chr8_-_145085616 1.694 NM_201384
PLEC
plectin
chr3_+_52325374 1.685 NM_015512
DNAH1
dynein, axonemal, heavy chain 1
chr7_+_129807467 1.682 NM_001868
CPA1
carboxypeptidase A1 (pancreatic)
chr9_+_91409746 1.679 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr8_-_124289107 1.657


chr19_-_40711034 1.656 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr11_-_2138984 1.655 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough transcript
chr22_+_29848923 1.653 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr10_+_112247614 1.649 NM_004419
DUSP5
dual specificity phosphatase 5
chrX_-_62487693 1.649 NM_001012968
SPIN4
spindlin family, member 4
chr9_-_37455384 1.641 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr1_+_15935395 1.614 NM_207348
SLC25A34
solute carrier family 25, member 34
chr1_-_12599934 1.607 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr9_+_123083540 1.600 GSN
gelsolin
chrX_+_153279764 1.597 NM_006013
RPL10
ribosomal protein L10
chr11_+_65754476 1.595 PACS1
phosphofurin acidic cluster sorting protein 1
chr3_+_127725851 1.593 NM_152889
CHST13
carbohydrate (chondroitin 4) sulfotransferase 13
chr19_-_40684638 1.592 NM_001035516
DMKN
dermokine
chrX_-_74062005 1.590 NM_001008537
KIAA2022
KIAA2022
chr15_-_50869379 1.588 NM_004498
ONECUT1
one cut homeobox 1
chr11_+_60727559 1.584 NM_001079807
PGA3
PGA4
pepsinogen 3, group I (pepsinogen A)
pepsinogen 4, group I (pepsinogen A)
chr8_+_145692916 1.577 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr1_-_10779291 1.575 NM_001079843
NM_017766
CASZ1

castor zinc finger 1

chr19_+_45998020 1.573 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr10_-_71002998 1.556 NM_020999
NEUROG3
neurogenin 3
chr17_-_53761119 1.554 NM_004758
NM_024418
BZRAP1

benzodiazapine receptor (peripheral) associated protein 1

chrX_-_19598912 1.552 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chrX_-_153698930 1.550 HMGN1P37
high-mobility group nucleosome binding domain 1 pseudogene 37
chr10_-_70846573 1.550 NM_001057
TACR2
tachykinin receptor 2
chr6_-_2580296 1.541 NM_152554
C6orf195
chromosome 6 open reading frame 195
chr12_-_121224676 1.541 NM_001014336
IL31
interleukin 31
chr21_-_41479035 1.539 NM_182832
PLAC4
placenta-specific 4
chr1_-_1139358 1.533 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr22_+_21318779 1.533 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr3_+_11009419 1.520 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr12_+_109956210 1.518 NM_015267
CUX2
cut-like homeobox 2
chr9_+_125158268 1.517 NM_173689
CRB2
crumbs homolog 2 (Drosophila)
chr1_-_43523825 1.517 NM_182517
NM_001164829
C1orf210

chromosome 1 open reading frame 210

chr16_+_69060325 1.505 FUK
fucokinase

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.53 1.04e-09 GO:0051239 regulation of multicellular organismal process
1.27 7.69e-09 GO:0023052 signaling
1.28 2.19e-08 GO:0007165 signal transduction
1.30 1.04e-07 GO:0048731 system development
1.26 3.24e-07 GO:0007275 multicellular organismal development
1.32 7.81e-07 GO:0048519 negative regulation of biological process
1.27 1.27e-06 GO:0048856 anatomical structure development
1.33 2.80e-06 GO:0048523 negative regulation of cellular process
1.23 7.16e-06 GO:0032502 developmental process
1.36 7.70e-06 GO:0007166 cell surface receptor linked signaling pathway
1.88 1.50e-05 GO:0044057 regulation of system process
1.21 2.16e-05 GO:0051716 cellular response to stimulus
1.89 2.86e-05 GO:0060284 regulation of cell development
1.31 3.63e-05 GO:0065008 regulation of biological quality
1.12 6.78e-05 GO:0065007 biological regulation
1.35 8.82e-05 GO:0023051 regulation of signaling
1.57 8.89e-05 GO:0045595 regulation of cell differentiation
1.47 1.53e-04 GO:0050793 regulation of developmental process
1.30 1.86e-04 GO:0030154 cell differentiation
1.29 2.18e-04 GO:0048869 cellular developmental process
2.53 2.71e-04 GO:0045761 regulation of adenylate cyclase activity
1.51 3.18e-04 GO:0007267 cell-cell signaling
1.31 3.25e-04 GO:0048513 organ development
1.43 4.02e-04 GO:0007154 cell communication
2.47 4.90e-04 GO:0031279 regulation of cyclase activity
2.37 5.19e-04 GO:0030817 regulation of cAMP biosynthetic process
1.35 5.24e-04 GO:0007399 nervous system development
2.31 5.60e-04 GO:0030802 regulation of cyclic nucleotide biosynthetic process
2.31 5.60e-04 GO:0030808 regulation of nucleotide biosynthetic process
1.30 6.05e-04 GO:0048583 regulation of response to stimulus
2.35 6.77e-04 GO:0030814 regulation of cAMP metabolic process
1.90 8.46e-04 GO:0050767 regulation of neurogenesis
2.42 8.67e-04 GO:0051339 regulation of lyase activity
2.25 1.18e-03 GO:0030799 regulation of cyclic nucleotide metabolic process
1.12 1.61e-03 GO:0050789 regulation of biological process
1.82 1.61e-03 GO:0051960 regulation of nervous system development
1.15 1.67e-03 GO:0032501 multicellular organismal process
1.97 1.71e-03 GO:0045664 regulation of neuron differentiation
1.76 2.32e-03 GO:0006140 regulation of nucleotide metabolic process
1.12 2.41e-03 GO:0050794 regulation of cellular process
1.23 2.70e-03 GO:0048518 positive regulation of biological process
1.32 3.00e-03 GO:0009653 anatomical structure morphogenesis
2.51 4.02e-03 GO:0051048 negative regulation of secretion
1.95 6.55e-03 GO:0051051 negative regulation of transport
1.41 6.60e-03 GO:0022008 neurogenesis
1.66 7.38e-03 GO:0090066 regulation of anatomical structure size
1.39 7.38e-03 GO:0009605 response to external stimulus
1.44 1.27e-02 GO:2000026 regulation of multicellular organismal development
1.67 1.37e-02 GO:0051240 positive regulation of multicellular organismal process
1.41 1.60e-02 GO:0048699 generation of neurons
1.31 2.11e-02 GO:0035556 intracellular signal transduction
1.35 2.35e-02 GO:0010646 regulation of cell communication
1.07 2.43e-02 GO:0009987 cellular process
1.37 2.79e-02 GO:0032879 regulation of localization
1.37 3.40e-02 GO:0042127 regulation of cell proliferation
1.30 3.42e-02 GO:0009966 regulation of signal transduction
1.51 3.60e-02 GO:0008284 positive regulation of cell proliferation
1.34 3.98e-02 GO:0051246 regulation of protein metabolic process
1.22 4.54e-02 GO:0042221 response to chemical stimulus
1.39 4.91e-02 GO:0051128 regulation of cellular component organization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.30 5.81e-06 GO:0044459 plasma membrane part
1.18 5.42e-05 GO:0071944 cell periphery
1.18 6.06e-05 GO:0005886 plasma membrane
1.36 2.64e-04 GO:0005887 integral to plasma membrane
1.34 5.13e-04 GO:0031226 intrinsic to plasma membrane
1.10 1.83e-03 GO:0016020 membrane
1.44 1.18e-02 GO:0030054 cell junction

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.47 4.28e-02 GO:0060589 nucleoside-triphosphatase regulator activity