Motif ID: TCF4_dimer.p2

Z-value: 2.271


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TCF4chr18_-_51406841-0.214.4e-01Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_30498948 3.660 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr11_+_63864263 3.166 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr22_-_49240594 2.885 SBF1
SET binding factor 1
chr9_+_139292094 2.808 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr11_+_817584 2.765 NM_173584
EFCAB4A
EF-hand calcium binding domain 4A
chr2_-_241484245 2.761 NM_001085437
C2orf54
chromosome 2 open reading frame 54
chr20_-_61669550 2.744 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chrX_-_135941498 2.697 NM_054021
GPR101
G protein-coupled receptor 101
chr22_+_20068039 2.574 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr11_+_70926718 2.515 NM_021046
KRTAP5-8
keratin associated protein 5-8
chr1_-_1840564 2.514 NM_178545
TMEM52
transmembrane protein 52
chr1_+_3360880 2.449 NM_014448
ARHGEF16
Rho guanine nucleotide exchange factor (GEF) 16
chr16_+_87232501 2.443 NM_013278
IL17C
interleukin 17C
chr16_-_87405817 2.425 NM_000485
NM_001030018
APRT

adenine phosphoribosyltransferase

chr8_-_145088679 2.357 NM_201383
PLEC
plectin
chr17_+_24095135 2.333 NM_004295
TRAF4
TNF receptor-associated factor 4
chrX_+_110226030 2.241 NM_002578
PAK3
p21 protein (Cdc42/Rac)-activated kinase 3
chr8_-_145609737 2.139 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr17_+_26060617 2.135


chr12_+_120944174 2.135 NM_001024808
NM_020993
BCL7A

B-cell CLL/lymphoma 7A

chr17_-_8643163 2.132 NM_152599
MFSD6L
major facilitator superfamily domain containing 6-like
chr15_-_75694674 2.045 LINGO1
leucine rich repeat and Ig domain containing 1
chr2_-_241270982 2.024 NM_001102467
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr16_+_56230707 2.015 NM_001145774
GPR56
G protein-coupled receptor 56
chr5_+_169465478 1.926 NM_012188
NM_144769
FOXI1

forkhead box I1

chr3_+_42702014 1.914 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr19_+_54883732 1.879 NM_001101340
C19orf76
chromosome 19 open reading frame 76
chr1_-_6585268 1.852 KLHL21
kelch-like 21 (Drosophila)
chr1_-_154205675 1.847 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_+_45799060 1.840 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr9_+_134927185 1.840 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr7_+_72486044 1.827 NM_003508
FZD9
frizzled homolog 9 (Drosophila)
chr7_-_1562272 1.808 NM_001097620
TMEM184A
transmembrane protein 184A
chr7_-_72822471 1.800 NM_001306
CLDN3
claudin 3
chr9_-_135379888 1.776 NM_001080483
TMEM8C
transmembrane protein 8C
chr14_-_105392671 1.772


chr1_+_1062137 1.770 LOC254099
hypothetical protein LOC254099
chr17_-_39700960 1.754 NM_000342
SLC4A1
solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr19_-_15252261 1.740 NM_014299
NM_058243
BRD4

bromodomain containing 4

chr16_+_711139 1.728 NM_023933
FAM173A
family with sequence similarity 173, member A
chr19_-_60587414 1.725 NM_001190764
LOC388564
hypothetical protein LOC388564
chr8_-_143692814 1.721 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr20_-_62052922 1.719 NM_001193379
UCKL1
uridine-cytidine kinase 1-like 1
chr12_+_108690199 1.718 C12orf34
chromosome 12 open reading frame 34
chr13_-_78075683 1.710 NM_006237
POU4F1
POU class 4 homeobox 1
chr16_+_4325142 1.700 GLIS2
GLIS family zinc finger 2
chr20_+_29870836 1.677 NM_033118
MYLK2
myosin light chain kinase 2
chr22_+_28446288 1.669 NM_182527
CABP7
calcium binding protein 7
chr19_+_3457264 1.655 NM_016263
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr17_+_71235324 1.647 ITGB4
integrin, beta 4
chr5_+_140844810 1.639 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr20_-_60375695 1.638 NM_005560
LAMA5
laminin, alpha 5
chr19_+_6415259 1.635 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr11_-_66945190 1.623 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr14_+_100270222 1.622 DLK1
delta-like 1 homolog (Drosophila)
chr12_+_4253143 1.614 NM_001759
CCND2
cyclin D2
chr1_+_2149993 1.600 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr22_-_20235372 1.593 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr19_+_43447262 1.587 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr2_+_233099113 1.585 NM_000751
CHRND
cholinergic receptor, nicotinic, delta
chr10_-_71002998 1.576 NM_020999
NEUROG3
neurogenin 3
chr11_-_407324 1.573 NM_001135053
NM_021805
SIGIRR

single immunoglobulin and toll-interleukin 1 receptor (TIR) domain

chr19_-_51829778 1.570 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr16_+_2954217 1.552 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr19_+_6723801 1.522


chr7_-_72761367 1.515 STX1A
syntaxin 1A (brain)
chr16_+_2138688 1.514 RAB26
RAB26, member RAS oncogene family
chr12_+_1799919 1.514 LRTM2
leucine-rich repeats and transmembrane domains 2
chr3_+_141879555 1.511 NM_152616
TRIM42
tripartite motif containing 42
chr19_+_43446937 1.507 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr16_+_2138608 1.505 NM_014353
RAB26
RAB26, member RAS oncogene family
chr17_+_71586857 1.503 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr4_+_3738093 1.500 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr7_-_127458231 1.496 NM_022143
LRRC4
leucine rich repeat containing 4
chr17_+_45008175 1.488 NM_007225
NXPH3
neurexophilin 3
chr15_+_81567327 1.485 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr22_-_37858871 1.484 CBX7
chromobox homolog 7
chr1_+_109827975 1.484 NM_153340
ATXN7L2
ataxin 7-like 2
chr8_-_142307854 1.484 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr16_+_2757655 1.481 SRRM2
serine/arginine repetitive matrix 2
chr1_+_100776280 1.477 NM_022049
GPR88
G protein-coupled receptor 88
chr9_-_139316523 1.468 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr9_-_33385265 1.452 AQP7
aquaporin 7
chr2_+_241279934 1.441 NM_198998
AQP12A
AQP12B
aquaporin 12A
aquaporin 12B
chr2_-_232499202 1.440 NM_024409
NPPC
natriuretic peptide C
chr19_-_1989937 1.424 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr17_+_73676219 1.421 NM_004710
SYNGR2
synaptogyrin 2
chr14_+_103675194 1.406 KIF26A
kinesin family member 26A
chr17_+_45993338 1.404 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr1_-_2451543 1.401 NM_001010926
HES5
hairy and enhancer of split 5 (Drosophila)
chr15_+_72906003 1.394 NM_001030005
CPLX3
complexin 3
chrX_-_16797895 1.391 NM_001198719
RBBP7
retinoblastoma binding protein 7
chr2_+_96566190 1.391 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr9_-_85342868 1.376 NM_174938
FRMD3
FERM domain containing 3
chr11_+_61204392 1.370 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr17_-_2561676 1.367 NM_015229
KIAA0664
KIAA0664
chr9_-_139060377 1.352 NPDC1
neural proliferation, differentiation and control, 1
chr1_+_112852892 1.344 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr5_+_1254709 1.343 NM_001003841
SLC6A19
solute carrier family 6 (neutral amino acid transporter), member 19
chr8_-_144583718 1.339 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr1_+_1971762 1.338 NM_002744
PRKCZ
protein kinase C, zeta
chr19_+_43447078 1.337 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr16_-_29781842 1.320 NM_006319
CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
chr20_-_538909 1.318 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr5_-_54317102 1.308 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_12599934 1.302 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr9_+_139006663 1.298 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr17_+_45900688 1.295 ACSF2
acyl-CoA synthetase family member 2
chr1_+_1557419 1.295 NM_006983
MMP23B
matrix metallopeptidase 23B
chr17_-_24253821 1.291 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr20_+_60906605 1.286 NM_007346
OGFR
opioid growth factor receptor
chr17_-_23716391 1.286 NM_001080837
SEBOX
SEBOX homeobox
chr1_-_74912009 1.284 NM_001002912
C1orf173
chromosome 1 open reading frame 173
chr16_+_84204424 1.283 NM_014615
KIAA0182
KIAA0182
chr21_+_36993860 1.282 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr9_-_139060285 1.280 NPDC1
neural proliferation, differentiation and control, 1
chr9_+_129893948 1.277 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr10_-_98935369 1.271 SLIT1
slit homolog 1 (Drosophila)
chr11_-_70971556 1.270 NM_001005405
KRTAP5-11
keratin associated protein 5-11
chr19_-_14177980 1.264 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr16_+_87765661 1.258 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr16_+_270606 1.251 NM_001176
ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma
chrX_+_110074124 1.248 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr16_-_87460514 1.245 NM_001080487
PABPN1L
poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr19_+_4983899 1.244


chr8_-_139995417 1.238 NM_152888
COL22A1
collagen, type XXII, alpha 1
chr22_-_35011703 1.238 MYH9
myosin, heavy chain 9, non-muscle
chr9_-_139042526 1.235 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr1_+_110456584 1.232 NM_203412
UBL4B
ubiquitin-like 4B
chr9_-_139184247 1.226 NM_001013653
LRRC26
leucine rich repeat containing 26
chr12_+_131797455 1.223 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr17_-_44226595 1.218 NM_173623
TTLL6
tubulin tyrosine ligase-like family, member 6
chr2_-_241480058 1.217 NM_024861
C2orf54
chromosome 2 open reading frame 54
chr5_+_176170041 1.215 NM_133369
UNC5A
unc-5 homolog A (C. elegans)
chr6_-_39398293 1.209 NM_001135105
NM_001135106
NM_001135107
NM_032115
KCNK16



potassium channel, subfamily K, member 16



chr13_-_49597776 1.208 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr9_-_130980302 1.206 IER5L
immediate early response 5-like
chr17_-_43390108 1.202 NM_024320
PRR15L
proline rich 15-like
chr8_+_143542378 1.199 NM_001702
BAI1
brain-specific angiogenesis inhibitor 1
chr19_+_12810258 1.196 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr17_+_24944605 1.193 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr19_+_54996613 1.191


chr10_-_98935570 1.188 SLIT1
slit homolog 1 (Drosophila)
chr11_-_64327197 1.183 NM_004579
MAP4K2
mitogen-activated protein kinase kinase kinase kinase 2
chr11_+_119616112 1.180 NM_014352
POU2F3
POU class 2 homeobox 3
chr10_-_21847126 1.177


chr22_-_39964001 1.174 CHADL
chondroadherin-like
chr1_+_18680010 1.171 NM_152375
KLHDC7A
kelch domain containing 7A
chr16_-_2099854 1.170 PKD1
polycystic kidney disease 1 (autosomal dominant)
chr14_+_104261578 1.169 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr1_-_3556420 1.161 NM_017818
WDR8
WD repeat domain 8
chr16_-_730889 1.160 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr10_+_112247614 1.158 NM_004419
DUSP5
dual specificity phosphatase 5
chr12_+_131705438 1.154 NM_012226
NM_016318
NM_170682
NM_170683
NM_174872
NM_174873
P2RX2





purinergic receptor P2X, ligand-gated ion channel, 2





chr2_-_96145614 1.152 NM_000682
ADRA2B
adrenergic, alpha-2B-, receptor
chr19_-_50964336 1.148 NM_175875
SIX5
SIX homeobox 5
chr9_-_139042416 1.138 ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_+_120820140 1.137 NM_002193
INHBB
inhibin, beta B
chr14_+_73775927 1.135 NM_182894
VSX2
visual system homeobox 2
chr5_+_132176921 1.135 NM_175873
ANKRD43
ankyrin repeat domain 43
chr11_-_64368616 1.132 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr3_+_50204026 1.126 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr10_+_46413551 1.126 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr9_+_101623957 1.126 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr19_-_60740246 1.123 NM_001101401
SBK2
SH3-binding domain kinase family, member 2
chr1_+_53300410 1.121 NM_153703
PODN
podocan
chr10_-_98470164 1.119 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr1_+_159943385 1.118 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr9_-_138757175 1.117 NM_001001712
LCN10
lipocalin 10
chr11_-_67163600 1.113 NM_005995
TBX10
T-box 10
chr11_+_384238 1.112 PKP3
plakophilin 3
chr17_-_77092569 1.111 ACTG1
actin, gamma 1
chr9_-_130980359 1.110 NM_203434
IER5L
immediate early response 5-like
chr11_+_63876924 1.107 CCDC88B
coiled-coil domain containing 88B
chrX_+_12066505 1.104 NM_014728
FRMPD4
FERM and PDZ domain containing 4
chrX_+_109548940 1.103 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr19_+_13066956 1.102 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_18584666 1.096 NM_012109
TMEM59L
transmembrane protein 59-like
chr11_+_56984702 1.092 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr13_+_26896614 1.085 NM_002097
GTF3A
general transcription factor IIIA
chr14_+_104244998 1.085 INF2
inverted formin, FH2 and WH2 domain containing
chr19_+_7834124 1.081 EVI5L
ecotropic viral integration site 5-like
chr9_-_139183675 1.076


chr8_-_144882679 1.076 FAM83H
family with sequence similarity 83, member H
chr11_+_70915960 1.076 NM_001012503
KRTAP5-7
keratin associated protein 5-7
chr3_+_122794859 1.075 NM_016298
FBXO40
F-box protein 40
chr19_+_8335010 1.073 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr8_-_29262240 1.072 NM_057158
DUSP4
dual specificity phosphatase 4
chr19_+_10392128 1.068 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_-_59438411 1.064 NM_024318
LILRB3
LILRA6
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr3_+_49034494 1.061 NDUFAF3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr12_-_50871953 1.059 NM_001081492
NM_182507
KRT80

keratin 80

chr13_+_112681626 1.059 NM_024979
MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_+_45008473 1.055 NXPH3
neurexophilin 3
chr2_+_10779191 1.055 NM_001039362
NM_144583
ATP6V1C2

ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2

chr17_+_4434582 1.054 NM_001114974
SMTNL2
smoothelin-like 2
chr17_+_21220260 1.053 NM_021012
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr11_+_384199 1.051 NM_007183
PKP3
plakophilin 3
chr5_-_148738980 1.050 NM_014443
IL17B
interleukin 17B
chr5_-_525916 1.048 LOC25845
hypothetical LOC25845

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.21 1.05e-13 GO:0007275 multicellular organismal development
1.23 5.98e-13 GO:0048731 system development
1.22 1.34e-12 GO:0048856 anatomical structure development
1.18 5.83e-11 GO:0032502 developmental process
1.29 7.56e-09 GO:0007399 nervous system development
1.23 3.65e-08 GO:0030154 cell differentiation
1.22 4.32e-07 GO:0048869 cellular developmental process
1.34 5.16e-07 GO:0022008 neurogenesis
1.15 8.84e-07 GO:0023052 signaling
1.26 9.97e-07 GO:0009653 anatomical structure morphogenesis
1.35 1.18e-06 GO:0048699 generation of neurons
1.09 1.33e-06 GO:0065007 biological regulation
1.38 1.87e-06 GO:0030182 neuron differentiation
1.21 8.23e-06 GO:0048513 organ development
1.32 8.97e-06 GO:0048468 cell development
1.26 1.21e-05 GO:0051239 regulation of multicellular organismal process
1.11 4.70e-05 GO:0032501 multicellular organismal process
1.14 5.54e-05 GO:0007165 signal transduction
1.50 8.18e-05 GO:0007411 axon guidance
1.20 1.14e-04 GO:0007166 cell surface receptor linked signaling pathway
1.28 1.41e-04 GO:0009605 response to external stimulus
1.08 1.59e-04 GO:0050794 regulation of cellular process
1.42 2.11e-04 GO:0032583 regulation of gene-specific transcription
1.08 2.24e-04 GO:0050789 regulation of biological process
1.16 2.91e-04 GO:0048518 positive regulation of biological process
1.21 3.70e-04 GO:0023051 regulation of signaling
1.17 4.98e-04 GO:0048523 negative regulation of cellular process
1.46 6.18e-04 GO:0044057 regulation of system process
1.26 9.90e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.30 1.73e-03 GO:2000026 regulation of multicellular organismal development
1.16 2.01e-03 GO:0048519 negative regulation of biological process
1.25 2.13e-03 GO:0007154 cell communication
1.30 2.23e-03 GO:0009790 embryo development
1.27 2.82e-03 GO:0040011 locomotion
1.27 3.20e-03 GO:0009888 tissue development
1.33 3.26e-03 GO:0048666 neuron development
1.42 3.26e-03 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.35 3.73e-03 GO:0006935 chemotaxis
1.35 3.73e-03 GO:0042330 taxis
1.17 3.86e-03 GO:0048583 regulation of response to stimulus
1.15 4.13e-03 GO:0048522 positive regulation of cellular process
1.44 4.39e-03 GO:0060284 regulation of cell development
1.25 7.06e-03 GO:0050793 regulation of developmental process
1.57 7.72e-03 GO:0003012 muscle system process
1.20 7.98e-03 GO:0009966 regulation of signal transduction
1.34 8.83e-03 GO:0000904 cell morphogenesis involved in differentiation
1.37 9.87e-03 GO:0007409 axonogenesis
1.43 1.25e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.15 1.28e-02 GO:0042221 response to chemical stimulus
1.29 1.32e-02 GO:0010628 positive regulation of gene expression
1.33 1.50e-02 GO:0007417 central nervous system development
1.28 1.52e-02 GO:0045595 regulation of cell differentiation
1.27 1.53e-02 GO:0007267 cell-cell signaling
1.36 1.56e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.30 1.87e-02 GO:0009887 organ morphogenesis
1.42 1.89e-02 GO:0006140 regulation of nucleotide metabolic process
1.26 2.23e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.33 2.56e-02 GO:0031175 neuron projection development
1.56 2.75e-02 GO:0006936 muscle contraction
1.10 2.97e-02 GO:0051716 cellular response to stimulus
1.34 3.16e-02 GO:0048812 neuron projection morphogenesis
1.31 3.19e-02 GO:0051253 negative regulation of RNA metabolic process
2.44 3.59e-02 GO:0071299 cellular response to vitamin A
1.14 4.02e-02 GO:0065008 regulation of biological quality
1.47 4.58e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.25 4.77e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.21 4.95e-02 GO:0010646 regulation of cell communication

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 1.24e-06 GO:0044459 plasma membrane part
1.39 1.41e-06 GO:0030054 cell junction
1.74 1.69e-04 GO:0043292 contractile fiber
1.76 1.98e-04 GO:0030016 myofibril
1.24 2.63e-04 GO:0044421 extracellular region part
1.11 2.72e-04 GO:0005886 plasma membrane
1.11 4.39e-04 GO:0071944 cell periphery
1.50 6.97e-04 GO:0016323 basolateral plasma membrane
1.26 1.37e-03 GO:0005615 extracellular space
1.68 2.72e-03 GO:0044449 contractile fiber part
1.70 6.96e-03 GO:0030017 sarcomere
1.35 8.38e-03 GO:0031012 extracellular matrix
1.14 1.07e-02 GO:0005576 extracellular region
1.36 2.79e-02 GO:0005578 proteinaceous extracellular matrix
1.31 3.36e-02 GO:0043005 neuron projection
1.05 3.60e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.30 4.18e-04 GO:0043565 sequence-specific DNA binding
1.25 4.48e-04 GO:0005102 receptor binding
1.23 1.64e-03 GO:0030528 transcription regulator activity
1.24 1.66e-03 GO:0001071 nucleic acid binding transcription factor activity
1.24 1.66e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.33 3.87e-03 GO:0060589 nucleoside-triphosphatase regulator activity
1.33 5.75e-03 GO:0030695 GTPase regulator activity