Motif ID: NFE2L1.p2

Z-value: 2.042


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFE2L1chr17_+_43480674-0.485.7e-02Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_88573949 3.111 NM_001001323
NM_001682
ATP2B1

ATPase, Ca++ transporting, plasma membrane 1

chr21_+_33844793 2.427 SON
SON DNA binding protein
chr6_+_55147029 2.130 NM_001526
HCRTR2
hypocretin (orexin) receptor 2
chr10_+_129237602 2.036 NM_001030013
NPS
neuropeptide S
chr9_-_106420305 1.899 NM_001001956
OR13C9
olfactory receptor, family 13, subfamily C, member 9
chr7_+_113853790 1.698 NM_001172767
NM_148899
FOXP2

forkhead box P2

chr11_-_57752923 1.696 NM_001004471
OR10Q1
olfactory receptor, family 10, subfamily Q, member 1
chrX_+_142794838 1.536 NM_001012989
UBE2NL
ubiquitin-conjugating enzyme E2N-like
chr4_-_68678181 1.502 NM_207407
TMPRSS11F
transmembrane protease, serine 11F
chr11_+_5925152 1.498 NM_001003443
OR56A3
olfactory receptor, family 56, subfamily A, member 3
chr1_+_246635918 1.414 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr1_-_157551072 1.401 NM_001004467
OR10J3
olfactory receptor, family 10, subfamily J, member 3
chr9_-_72926333 1.400 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr14_-_20969706 1.391 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr2_-_215967442 1.387 FN1
fibronectin 1
chr10_+_128583984 1.385 NM_001380
DOCK1
dedicator of cytokinesis 1
chr9_+_21399132 1.381 NM_002170
IFNA8
interferon, alpha 8
chr6_-_46155937 1.340 NM_001114086
CLIC5
chloride intracellular channel 5
chr2_+_191009265 1.329 MFSD6
major facilitator superfamily domain containing 6
chr2_+_228045121 1.327 NM_001135187
NM_001135188
NM_001135189
NM_004504
AGFG1



ArfGAP with FG repeats 1



chrX_-_32340291 1.322 NM_004011
NM_004012
DMD

dystrophin

chr12_-_44919818 1.310 SLC38A1
solute carrier family 38, member 1
chr2_+_228045053 1.293 AGFG1
ArfGAP with FG repeats 1
chr10_-_98315090 1.287 TM9SF3
transmembrane 9 superfamily member 3
chr9_-_21375258 1.287 NM_000605
IFNA2
interferon, alpha 2
chr9_-_21156609 1.283 NM_002175
IFNA21
interferon, alpha 21
chr11_-_13474101 1.272 NM_000315
PTH
parathyroid hormone
chr11_-_55815113 1.259 NM_001005199
OR8H1
olfactory receptor, family 8, subfamily H, member 1
chr17_+_36665161 1.253 NM_030975
KRTAP9-9
keratin associated protein 9-9
chr17_+_36642240 1.252 NM_031962
KRTAP9-9
KRTAP9-3
keratin associated protein 9-9
keratin associated protein 9-3
chr11_-_62753574 1.232 NM_199352
SLC22A25
solute carrier family 22, member 25
chr1_-_157772420 1.208 NM_001004469
OR10J5
olfactory receptor, family 10, subfamily J, member 5
chrX_-_33267646 1.182 NM_000109
DMD
dystrophin
chr12_+_84792203 1.175 NM_006183
NTS
neurotensin
chr10_-_108448990 1.165 SORCS1
sortilin-related VPS10 domain containing receptor 1
chr9_-_16717887 1.164 BNC2
basonuclin 2
chr11_-_6005546 1.140 NM_001001917
OR56A1
olfactory receptor, family 56, subfamily A, member 1
chr13_+_48692472 1.119 NM_001507
MLNR
motilin receptor
chr8_-_79880095 1.112 NM_000880
IL7
interleukin 7
chr3_+_171619346 1.096 NM_005602
CLDN11
claudin 11
chr9_-_21340885 1.090 NM_021002
IFNA6
interferon, alpha 6
chr2_+_88148413 1.087 NM_198274
SMYD1
SET and MYND domain containing 1
chr11_-_7917642 1.082 NM_001003745
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr11_+_55869996 1.080 NM_001002907
OR8K1
olfactory receptor, family 8, subfamily K, member 1
chr11_+_123945102 1.078 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr22_+_27998367 1.065 EWSR1
Ewing sarcoma breakpoint region 1
chr9_-_85773899 1.063 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr1_-_156784518 1.060 NM_001005189
OR6Y1
olfactory receptor, family 6, subfamily Y, member 1
chr2_-_55053398 1.056


chr22_-_31732648 1.051 NM_003490
NM_133633
SYN3

synapsin III

chr2_+_211129567 1.046 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr17_-_3248453 1.043 NM_003553
OR1E1
olfactory receptor, family 1, subfamily E, member 1
chr18_+_52575442 1.041 WDR7
WD repeat domain 7
chr22_-_37214480 1.006 NM_001098505
NM_030881
DDX17

DEAD (Asp-Glu-Ala-Asp) box polypeptide 17

chr1_-_157014048 1.000 NM_001005278
OR6N2
olfactory receptor, family 6, subfamily N, member 2
chr11_+_61352348 0.993 FADS2
fatty acid desaturase 2
chr11_-_27700180 0.988 NM_170731
BDNF
brain-derived neurotrophic factor
chr11_+_26310253 0.987 NM_031418
ANO3
anoctamin 3
chr5_+_132237253 0.987 NM_052971
LEAP2
liver expressed antimicrobial peptide 2
chr11_+_88550687 0.985 NM_000372
TYR
tyrosinase (oculocutaneous albinism IA)
chr12_-_18782184 0.979 NM_033123
PLCZ1
phospholipase C, zeta 1
chr4_+_99401543 0.976 NM_001100426
NM_001100427
NM_001100428
NM_001100429
NM_001100430
NM_021159
RAP1GDS1





RAP1, GTP-GDP dissociation stimulator 1





chr5_-_178977441 0.974 HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr6_+_89847183 0.966 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_-_157003095 0.951 NM_001005185
OR6N1
olfactory receptor, family 6, subfamily N, member 1
chr1_-_156635879 0.936 NM_001004475
OR10T2
olfactory receptor, family 10, subfamily T, member 2
chr1_+_93830106 0.935 LOC100129046
hypothetical LOC100129046
chr2_-_74455161 0.928 NM_001135041
NM_023019
DCTN1

dynactin 1

chr11_-_48330574 0.922 NM_001005513
OR4C45
olfactory receptor, family 4, subfamily C, member 45
chr12_+_18782307 0.917 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr5_+_147562531 0.913 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr1_+_93830169 0.913 LOC100129046
hypothetical LOC100129046
chr7_-_11838260 0.903 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr1_+_246718487 0.896 NM_001004697
OR2T5
olfactory receptor, family 2, subfamily T, member 5
chr8_+_32698892 0.894 NM_001159996
NRG1
neuregulin 1
chr17_-_8602601 0.893 NM_001128076
SPDYE4
speedy homolog E4 (Xenopus laevis)
chr17_+_15843832 0.891 TTC19
tetratricopeptide repeat domain 19
chr14_+_28306633 0.881 FOXG1
forkhead box G1
chr11_+_61352209 0.881 NM_004265
FADS2
fatty acid desaturase 2
chr8_+_118216517 0.880 NM_001172814
NM_173851
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr4_+_183302105 0.880 ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr1_-_71285847 0.880 NM_001126044
NM_198714
NM_198715
NM_198716
NM_198717
NM_198718
NM_198719
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr14_-_21108714 0.876 NM_001005465
OR10G3
olfactory receptor, family 10, subfamily G, member 3
chrX_-_127014020 0.875 NM_138289
ACTRT1
actin-related protein T1
chr9_-_21358005 0.872 NM_006900
IFNA1
IFNA13
interferon, alpha 1
interferon, alpha 13
chr3_-_187124290 0.868 TRA2B
transformer 2 beta homolog (Drosophila)
chr2_+_115635982 0.864 NM_001178034
NM_001004360
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr11_+_6854431 0.862 NM_207186
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr14_+_74968589 0.861 NM_001135049
JDP2
Jun dimerization protein 2
chr14_-_94669547 0.858 NM_001195573
DICER1
dicer 1, ribonuclease type III
chr16_-_21439195 0.854 SLC7A5P2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 pseudogene 2
chr3_-_181237210 0.849 NM_016559
PEX5L
peroxisomal biogenesis factor 5-like
chr4_-_39199527 0.848 UGDH
UDP-glucose 6-dehydrogenase
chr5_+_34720368 0.847 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr5_-_112798436 0.846 NM_032028
TSSK1B
testis-specific serine kinase 1B
chr8_-_30826074 0.845 NM_031271
TEX15
testis expressed 15
chr1_-_150328153 0.845 NM_001008536
TCHHL1
trichohyalin-like 1
chr22_+_29696662 0.840


chr17_-_25112393 0.837 SSH2
slingshot homolog 2 (Drosophila)
chr15_+_71953020 0.836 NM_153356
TBC1D21
TBC1 domain family, member 21
chr4_-_164754106 0.836 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr3_-_155630197 0.834 NM_001038705
GPR149
G protein-coupled receptor 149
chr17_-_36181927 0.832 NM_181539
KRT26
keratin 26
chr8_-_67253234 0.827 NM_000756
CRH
corticotropin releasing hormone
chrX_+_78313124 0.824 NM_032553
GPR174
G protein-coupled receptor 174
chr11_-_123695302 0.823 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr20_+_9406460 0.811 PLCB4
phospholipase C, beta 4
chr9_-_21067804 0.806 NM_002176
IFNB1
interferon, beta 1, fibroblast
chr1_+_27972269 0.803 NM_177424
STX12
syntaxin 12
chr14_+_74353417 0.803 YLPM1
YLP motif containing 1
chr6_+_89847019 0.800 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr14_-_46882144 0.796 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr14_-_93493519 0.793 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr15_+_92700167 0.784 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr6_+_72979234 0.775 NM_001168407
NM_001168408
RIMS1

regulating synaptic membrane exocytosis 1

chr10_+_115793795 0.770 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr14_-_35859545 0.769 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr15_+_46271158 0.766 NM_001145668
CTXN2
SLC12A1
cortexin 2
solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr20_-_33705244 0.757 NM_003915
CPNE1
copine I
chr10_-_45350804 0.757 NM_001002266
MARCH8
membrane-associated ring finger (C3HC4) 8
chr1_-_156923111 0.755 NM_003126
SPTA1
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr2_-_240634161 0.751 NM_173351
OR6B3
olfactory receptor, family 6, subfamily B, member 3
chr4_-_123761615 0.748 NM_021803
IL21
interleukin 21
chr2_+_36436873 0.746 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_58967192 0.742 NM_001004728
OR5A1
olfactory receptor, family 5, subfamily A, member 1
chr1_+_156701895 0.740 NM_001004473
OR10K1
olfactory receptor, family 10, subfamily K, member 1
chr18_+_75760434 0.737


chrX_-_10495476 0.737 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr3_+_125296217 0.737 NM_001024660
NM_003947
KALRN

kalirin, RhoGEF kinase

chr8_+_94999167 0.735 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr14_-_59264044 0.734 NM_206857
RTN1
reticulon 1
chr1_-_246525502 0.728 NM_001004692
OR2T12
olfactory receptor, family 2, subfamily T, member 12
chr3_+_103051015 0.727 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_156657279 0.724 NM_001004476
OR10K2
olfactory receptor, family 10, subfamily K, member 2
chr11_-_55661769 0.721 NM_001004064
OR8J3
olfactory receptor, family 8, subfamily J, member 3
chr14_-_19572756 0.719 NM_001004714
OR4K13
olfactory receptor, family 4, subfamily K, member 13
chr14_+_66901237 0.717 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr11_+_77452550 0.716 NM_003251
THRSP
thyroid hormone responsive
chr15_+_61356801 0.716 NM_001145646
NM_031301
APH1B

anterior pharynx defective 1 homolog B (C. elegans)

chr17_-_36165050 0.715 NM_181534
KRT25
keratin 25
chr3_-_54937001 0.712 NM_020678
LRTM1
leucine-rich repeats and transmembrane domains 1
chr11_+_55629094 0.711 NM_001005200
OR8H2
olfactory receptor, family 8, subfamily H, member 2
chr11_+_55189189 0.710 NM_001004704
OR4C6
olfactory receptor, family 4, subfamily C, member 6
chr5_-_145464124 0.708 NM_001029869
PLAC8L1
PLAC8-like 1
chr3_-_110155237 0.708 NM_005459
GUCA1C
guanylate cyclase activator 1C
chr5_-_58688428 0.707 NM_001197219
PDE4D
phosphodiesterase 4D, cAMP-specific
chr15_+_89570333 0.703 SV2B
synaptic vesicle glycoprotein 2B
chr11_-_9243408 0.703 NM_015213
DENND5A
DENN/MADD domain containing 5A
chr8_+_104582151 0.702 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr2_-_166638376 0.701 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr1_+_168381811 0.701 NM_001136107
METTL11B
methyltransferase like 11B
chr10_+_86121526 0.698 FAM190B
family with sequence similarity 190, member B
chr14_+_100365162 0.682 MEG3
maternally expressed 3 (non-protein coding)
chr11_-_56166490 0.681 NM_001002925
OR5AP2
olfactory receptor, family 5, subfamily AP, member 2
chr3_+_160473784 0.680 SCHIP1
schwannomin interacting protein 1
chr9_+_106371269 0.674 NM_001004483
OR13C8
olfactory receptor, family 13, subfamily C, member 8
chr13_-_32658215 0.673 NM_178007
STARD13
StAR-related lipid transfer (START) domain containing 13
chr8_+_104900591 0.673 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr18_+_57308754 0.671 NM_031891
CDH20
cadherin 20, type 2
chr16_+_88467518 0.671 TCF25
transcription factor 25 (basic helix-loop-helix)
chr14_-_50631407 0.670 TRIM9
tripartite motif containing 9
chr12_-_10853940 0.669 NM_023917
TAS2R9
taste receptor, type 2, member 9
chr2_+_135392879 0.667 CCNT2
cyclin T2
chr20_+_155898 0.662 NM_080831
DEFB129
defensin, beta 129
chr12_-_3472245 0.661 LOC100129223
hypothetical LOC100129223
chr17_-_3283884 0.659 NM_003554
OR1E2
olfactory receptor, family 1, subfamily E, member 2
chr20_+_2892918 0.659 PTPRA
protein tyrosine phosphatase, receptor type, A
chr11_+_5714253 0.657 NM_001005180
OR56B1
olfactory receptor, family 56, subfamily B, member 1
chr1_+_158413824 0.656 NM_001001734
ATP1A4
ATPase, Na+/K+ transporting, alpha 4 polypeptide
chr16_-_88656092 0.654 NM_052996
PRDM7
PR domain containing 7
chr2_+_214984705 0.653 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr11_-_83706027 0.650 DLG2
discs, large homolog 2 (Drosophila)
chr18_-_29882555 0.649 NM_001198549
NOL4
nucleolar protein 4
chr5_+_133735004 0.649 UBE2B
ubiquitin-conjugating enzyme E2B (RAD6 homolog)
chr1_-_246503738 0.648 NM_001004695
OR2T33
olfactory receptor, family 2, subfamily T, member 33
chr11_-_123353607 0.644 NM_001004474
OR10S1
olfactory receptor, family 10, subfamily S, member 1
chr1_+_69998445 0.643 NM_020794
LRRC7
leucine rich repeat containing 7
chr20_+_19903778 0.641 RIN2
Ras and Rab interactor 2
chr12_+_6517600 0.637


chr16_+_15503623 0.637 NM_001142469
C16orf45
chromosome 16 open reading frame 45
chr3_-_56784634 0.637 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr9_-_21177529 0.636 NM_021068
IFNA4
interferon, alpha 4
chr11_+_48241988 0.632 NM_001004726
OR4X1
olfactory receptor, family 4, subfamily X, member 1
chr14_+_100270222 0.631 DLK1
delta-like 1 homolog (Drosophila)
chr4_+_158361185 0.630 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr16_-_71549149 0.629 ZFHX3
zinc finger homeobox 3
chr11_-_57883117 0.628 NM_001005489
OR5B17
olfactory receptor, family 5, subfamily B, member 17
chr12_-_21649019 0.628 NM_021957
GYS2
glycogen synthase 2 (liver)
chr11_+_55776251 0.627 NM_001004747
OR5T3
olfactory receptor, family 5, subfamily T, member 3
chr3_+_160473729 0.626 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr5_-_34020445 0.626 NM_001012509
NM_016180
SLC45A2

solute carrier family 45, member 2

chr11_+_55362802 0.625 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr19_+_39402167 0.625 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr6_+_52159143 0.623 NM_002190
IL17A
interleukin 17A
chr5_+_113726203 0.623 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_156991133 0.622 NM_001005184
OR6K6
olfactory receptor, family 6, subfamily K, member 6
chr2_+_135392857 0.622 NM_001241
NM_058241
CCNT2

cyclin T2

chr11_+_55884266 0.619 NM_001005205
OR8J1
olfactory receptor, family 8, subfamily J, member 1
chr14_+_19513442 0.617 NM_001005486
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr3_-_193609531 0.615 NM_021032
FGF12
fibroblast growth factor 12

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.47 5.23e-96 GO:0007608 sensory perception of smell
3.16 1.17e-82 GO:0007606 sensory perception of chemical stimulus
2.30 5.81e-57 GO:0007600 sensory perception
1.91 3.95e-49 GO:0050877 neurological system process
1.80 5.93e-49 GO:0003008 system process
1.26 2.13e-20 GO:0032501 multicellular organismal process
1.21 1.55e-17 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.31 1.00e-23 GO:0071944 cell periphery
1.31 2.34e-23 GO:0005886 plasma membrane
1.17 9.00e-10 GO:0016021 integral to membrane
1.15 3.61e-09 GO:0044425 membrane part
1.13 8.68e-09 GO:0016020 membrane
1.16 1.68e-08 GO:0031224 intrinsic to membrane
1.23 4.27e-03 GO:0005856 cytoskeleton
1.03 4.61e-03 GO:0044464 cell part
1.03 4.84e-03 GO:0005623 cell
1.28 4.88e-03 GO:0044430 cytoskeletal part

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.59 2.77e-100 GO:0004984 olfactory receptor activity
2.28 9.35e-58 GO:0004930 G-protein coupled receptor activity
1.85 2.29e-41 GO:0004888 transmembrane receptor activity
1.60 1.26e-28 GO:0004872 receptor activity
1.49 1.47e-24 GO:0004871 signal transducer activity
1.49 1.47e-24 GO:0060089 molecular transducer activity