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Motif ID: PRDM1.p3

Z-value: 1.158

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_21106291	3.005		APOB	apolipoprotein B (including Ag(x) antigen)
chr5_+_73145098	1.583		RGNEF	190 kDa guanine nucleotide exchange factor
chr15_+_94677572	1.568	NM_001145157	NR2F2	nuclear receptor subfamily 2, group F, member 2
chr20_+_56904042	1.478		GNAS	GNAS complex locus
chr1_+_210848763	1.453		ATF3	activating transcription factor 3
chr14_+_23675233	1.326		PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr14_+_23675206	1.299	NM_006263 NM_176783	PSME1	proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_+_210848726	1.258		ATF3	activating transcription factor 3
chr1_+_210848592	1.257	NM_001040619 NM_001674	ATF3	activating transcription factor 3
chr2_+_205118801	1.232		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr1_-_8406288	1.217	NM_001042682	RERE	arginine-glutamic acid dipeptide (RE) repeats
chr12_-_69289889	1.125	NM_002837	PTPRB	protein tyrosine phosphatase, receptor type, B
chr10_+_92970487	1.106		PCGF5	polycomb group ring finger 5
chr1_-_7998265	1.055		ERRFI1	ERBB receptor feedback inhibitor 1
chr1_+_220884257	1.021		MIA3	melanoma inhibitory activity family, member 3
chr2_+_205118961	0.952		PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr6_+_126282078	0.926		NCOA7	nuclear receptor coactivator 7
chr9_-_34700062	0.917	NM_002989	CCL21	chemokine (C-C motif) ligand 21
chr20_+_13924263	0.895		MACROD2	MACRO domain containing 2
chr1_-_142536082	0.814
chr11_-_77730573	0.807	NM_012296	GAB2	GRB2-associated binding protein 2
chr1_+_166172545	0.786		DCAF6	DDB1 and CUL4 associated factor 6
chr10_+_92970302	0.782	NM_032373	PCGF5	polycomb group ring finger 5
chr4_-_153523113	0.781	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chr2_+_205118710	0.740	NM_057177 NM_152526 NM_205863	PARD3B	par-3 partitioning defective 3 homolog B (C. elegans)
chr11_+_35641234	0.730		TRIM44	tripartite motif containing 44
chr3_+_186529376	0.729		MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr4_+_146623405	0.720	NM_001003688	SMAD1	SMAD family member 1
chr20_+_56903595	0.698		GNAS	GNAS complex locus
chr1_+_166172420	0.689	NM_001017977 NM_001198956 NM_001198957 NM_018442	DCAF6	DDB1 and CUL4 associated factor 6
chr14_-_23771399	0.668		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr14_+_57781308	0.645	NM_002788 NM_152132	PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr1_-_111548440	0.643		DENND2D	DENN/MADD domain containing 2D
chr14_-_23771312	0.629		NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr2_-_45648608	0.623		SRBD1	S1 RNA binding domain 1
chr8_+_97575196	0.604		SDC2	syndecan 2
chr16_-_46738061	0.601	NM_033226	ABCC12	ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr3_+_120495906	0.583	NM_020754	ARHGAP31	Rho GTPase activating protein 31
chr15_-_35180656	0.579	NM_002399	MEIS2	Meis homeobox 2
chr2_+_230989114	0.567	NM_001080391 NM_003113	SP100	SP100 nuclear antigen
chr8_+_96215118	0.564	NM_024613	PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr7_-_11643113	0.562		THSD7A	thrombospondin, type I, domain containing 7A
chr2_+_230989177	0.561		SP100	SP100 nuclear antigen
chr8_+_97575071	0.555		SDC2	syndecan 2
chr2_+_165858586	0.550	NM_021007	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr20_+_13924014	0.546	NM_080676	MACROD2	MACRO domain containing 2
chr14_-_23685629	0.546	NM_002818	PSME2	proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr14_+_57781352	0.544		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr2_+_234209838	0.543	NM_019075	UGT1A10	UDP glucuronosyltransferase 1 family, polypeptide A10
chr14_-_23771401	0.541	NM_006156	NEDD8	neural precursor cell expressed, developmentally down-regulated 8
chr11_+_32069183	0.539		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr2_-_19421852	0.534	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr14_+_23771464	0.534	NM_001002000 NM_001002001	GMPR2	guanosine monophosphate reductase 2
chr20_+_336693	0.532	NM_006462 NM_031229	RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr20_+_336963	0.527		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr4_+_76868763	0.525		USO1	USO1 vesicle docking protein homolog (yeast)
chr14_+_57781210	0.517		PSMA3	proteasome (prosome, macropain) subunit, alpha type, 3
chr2_+_230900121	0.512	NM_138402	SP140L	SP140 nuclear body protein-like
chr16_+_49333513	0.510	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr2_+_230989150	0.502		SP100	SP100 nuclear antigen
chr6_+_32929902	0.496	NM_002800	PSMB9	proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr10_-_35143900	0.487	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr8_+_96215144	0.474		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr7_-_42938255	0.467		PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr8_+_97575052	0.466	NM_002998	SDC2	syndecan 2
chr1_-_146398501	0.461		LOC100286793 FLJ39739	hypothetical LOC100286793 hypothetical FLJ39739
chr1_+_149638633	0.459	NM_002796	PSMB4	proteasome (prosome, macropain) subunit, beta type, 4
chr20_+_336717	0.456		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr8_+_97575244	0.456		SDC2	syndecan 2
chr16_+_49333461	0.453	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr5_+_161209969	0.452	NM_001127647	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr7_-_42938304	0.447	NM_002787	PSMA2	proteasome (prosome, macropain) subunit, alpha type, 2
chr15_-_53996597	0.444	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr6_-_112682401	0.428		LAMA4	laminin, alpha 4
chr9_-_116608113	0.423	NM_005118	TNFSF15	tumor necrosis factor (ligand) superfamily, member 15
chr6_-_112682459	0.423	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr4_+_76868830	0.422		USO1	USO1 vesicle docking protein homolog (yeast)
chr1_+_158063130	0.418		SLAMF8	SLAM family member 8
chr7_+_42938463	0.417	NM_031903	MRPL32	mitochondrial ribosomal protein L32
chr9_+_96806235	0.412		C9orf3	chromosome 9 open reading frame 3
chr9_-_16717887	0.410		BNC2	basonuclin 2
chr8_-_79880095	0.400	NM_000880	IL7	interleukin 7
chr4_+_142777172	0.394	NM_000585 NM_172174	IL15	interleukin 15
chr1_-_143232464	0.390
chr12_+_25096472	0.389	NM_006152	LRMP	lymphoid-restricted membrane protein
chr18_+_18989786	0.388	NM_138375	CABLES1	Cdk5 and Abl enzyme substrate 1
chr6_-_112682573	0.386		LAMA4	laminin, alpha 4
chr11_+_28088406	0.377		METTL15	methyltransferase like 15
chr2_+_6935246	0.375	NM_080657	RSAD2	radical S-adenosyl methionine domain containing 2
chr8_+_39890484	0.374	NM_002164	IDO1	indoleamine 2,3-dioxygenase 1
chr20_+_336941	0.372		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr13_+_107720475	0.371		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr5_-_142795269	0.360	NM_001018074 NM_001018075 NM_001018077	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr9_+_108665168	0.357	NM_021224	ZNF462	zinc finger protein 462
chr14_+_23982017	0.353
chr2_+_234191029	0.348	NM_019076	UGT1A8	UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_-_146543016	0.346
chr2_-_189752575	0.343	NM_000393	COL5A2	collagen, type V, alpha 2
chr1_+_158063278	0.335		SLAMF8	SLAM family member 8
chr3_-_161584137	0.327	NM_001190242	IFT80	intraflagellar transport 80 homolog (Chlamydomonas)
chr8_-_145132551	0.323		PARP10	poly (ADP-ribose) polymerase family, member 10
chr8_-_145132582	0.316	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr5_-_37220702	0.312		C5orf42	chromosome 5 open reading frame 42
chr1_-_166171838	0.307	NM_015415	BRP44	brain protein 44
chr4_-_76868581	0.302
chr1_-_142535878	0.298		LOC100286793 FLJ39739	hypothetical LOC100286793 hypothetical FLJ39739
chr12_+_68923043	0.297	NM_014515	CNOT2	CCR4-NOT transcription complex, subunit 2
chr20_+_337346	0.291		RBCK1	RanBP-type and C3HC4-type zinc finger containing 1
chr4_+_76868850	0.287	NM_003715	USO1	USO1 vesicle docking protein homolog (yeast)
chr4_+_88075176	0.287	NM_001166693	AFF1	AF4/FMR2 family, member 1
chr14_-_68329407	0.285	NM_004926	ZFP36L1	zinc finger protein 36, C3H type-like 1
chr5_+_139869819	0.284
chr1_-_152847256	0.283		ADAR	adenosine deaminase, RNA-specific
chr11_-_28086277	0.281	NM_031217	KIF18A	kinesin family member 18A
chr14_+_101297887	0.280	NM_001161725 NM_001161726	PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr11_-_40272239	0.279	NM_020929	LRRC4C	leucine rich repeat containing 4C
chr11_-_28086222	0.275		KIF18A	kinesin family member 18A
chr3_+_115099007	0.269	NM_001172105	GRAMD1C	GRAM domain containing 1C
chr14_+_72594985	0.268		RBM25	RNA binding motif protein 25
chr11_-_28086263	0.268		KIF18A	kinesin family member 18A
chr11_+_64946848	0.268
chr21_+_42807052	0.267		SLC37A1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr6_-_112682038	0.266		LAMA4	laminin, alpha 4
chr1_-_166171702	0.265		BRP44	brain protein 44
chr3_+_189354167	0.264	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr16_-_71650034	0.258	NM_001164766	ZFHX3	zinc finger homeobox 3
chr16_+_55580910	0.255	NM_032206	NLRC5	NLR family, CARD domain containing 5
chr10_-_6059460	0.249	NM_002189 NM_172200	IL15RA	interleukin 15 receptor, alpha
chr13_+_107720206	0.241		TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr19_-_53239030	0.236	NM_019855	CABP5	calcium binding protein 5
chr8_-_29176490	0.233	NM_015254	KIF13B	kinesin family member 13B
chr11_+_64946820	0.227		NEAT1	nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr10_+_63478974	0.227		ARID5B	AT rich interactive domain 5B (MRF1-like)
chr1_-_152847301	0.226	NM_001111 NM_015840 NM_015841	ADAR	adenosine deaminase, RNA-specific
chr14_+_72595020	0.225		RBM25	RNA binding motif protein 25
chr11_-_5662762	0.225	NM_033034 NM_033092 NM_033093	TRIM5	tripartite motif containing 5
chr1_-_143232526	0.223		FAM91A2	family with sequence similarity 91, member A2
chr10_+_69539255	0.217	NM_032578	MYPN	myopalladin
chr3_-_189354510	0.217		LOC339929	hypothetical LOC339929
chr12_+_11694172	0.216		ETV6	ets variant 6
chr10_+_91051685	0.213	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr6_-_11887265	0.212	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr6_-_33389825	0.208		TAPBP	TAP binding protein (tapasin)
chr11_-_4371463	0.208	NM_003141	TRIM21	tripartite motif containing 21
chr1_-_143232275	0.204		LOC728855	hypothetical LOC728855
chr11_+_28086373	0.203	NM_001113528 NM_152636	METTL15	methyltransferase like 15
chr16_-_70763849	0.201	NM_001160213	PMFBP1	polyamine modulated factor 1 binding protein 1
chr3_-_11598829	0.197	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr1_+_158063102	0.196	NM_020125	SLAMF8	SLAM family member 8
chr2_-_202216451	0.194	NM_001044385	ALS2CR4	amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4
chr6_-_28663045	0.187	NM_052923	SCAND3	SCAN domain containing 3
chr3_+_108724472	0.187	NM_001142568 NM_020235	BBX	bobby sox homolog (Drosophila)
chr9_+_101717278	0.186		STX17	syntaxin 17
chr12_-_55134692	0.174	NM_012064	MIP	major intrinsic protein of lens fiber
chr5_+_49998528	0.173	NM_001178056 NM_024615	PARP8	poly (ADP-ribose) polymerase family, member 8
chr6_-_33389768	0.171		TAPBP	TAP binding protein (tapasin)
chr1_-_159435440	0.168	NM_005099	ADAMTS4	ADAM metallopeptidase with thrombospondin type 1 motif, 4
chr12_-_55791443	0.163	NM_001178078 NM_001178080 NM_001178081 NM_003153	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr11_-_85015961	0.161	NM_001142699	DLG2	discs, large homolog 2 (Drosophila)
chr6_-_105691675	0.160		BVES	blood vessel epicardial substance
chr13_+_107719977	0.160	NM_001145645 NM_006573	TNFSF13B	tumor necrosis factor (ligand) superfamily, member 13b
chr2_-_37164919	0.159		HEATR5B	HEAT repeat containing 5B
chr3_+_69998064	0.158	NM_198177	MITF	microphthalmia-associated transcription factor
chr11_-_125153914	0.158	NM_212555	PATE2	prostate and testis expressed 2
chr14_-_22549168	0.158	NM_001130706 NM_001130708 NM_021944	C14orf93	chromosome 14 open reading frame 93
chr2_-_144711375	0.157	NM_024659	GTDC1	glycosyltransferase-like domain containing 1
chr14_-_23981493	0.152	NM_020195	SDR39U1	short chain dehydrogenase/reductase family 39U, member 1
chr7_+_134483305	0.152	NM_018295	TMEM140	transmembrane protein 140
chr7_-_105106844	0.152	NM_138495	ATXN7L1	ataxin 7-like 1
chr9_+_109085372	0.151		RAD23B	RAD23 homolog B (S. cerevisiae)
chr9_-_14858974	0.151		FREM1	FRAS1 related extracellular matrix 1
chr16_-_10696285	0.150	NM_144674	TEKT5	tektin 5
chr1_-_116185215	0.145	NM_005599	NHLH2	nescient helix loop helix 2
chr22_+_38903825	0.143	NM_001162501 NM_015088	TNRC6B	trinucleotide repeat containing 6B
chr16_-_70763524	0.140	NM_031293	PMFBP1	polyamine modulated factor 1 binding protein 1
chr7_+_89681069	0.140	NM_001040666	STEAP2	six transmembrane epithelial antigen of the prostate 2
chr12_+_27511009	0.137	NM_001145010	C12orf70	chromosome 12 open reading frame 70
chr11_+_5602782	0.135	NM_021616	TRIM34	tripartite motif containing 34
chr8_-_9046460	0.134		PPP1R3B	protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr1_-_146543102	0.133
chr1_+_159435728	0.131	NM_004550	NDUFS2	NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr15_-_40537002	0.131	NM_022473	ZFP106	zinc finger protein 106 homolog (mouse)
chr17_+_53602013	0.130	NM_001004707	OR4D2	olfactory receptor, family 4, subfamily D, member 2
chr7_+_134114701	0.129	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr12_-_55791388	0.128		STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr8_+_143805595	0.128	NM_016647	C8orf55	chromosome 8 open reading frame 55
chr10_-_113923507	0.127		GPAM	glycerol-3-phosphate acyltransferase, mitochondrial
chr9_+_109085337	0.127	NM_002874	RAD23B	RAD23 homolog B (S. cerevisiae)
chr20_-_47327998	0.126	NM_021035	ZNFX1	zinc finger, NFX1-type containing 1
chr8_+_97726757	0.123		PGCP	plasma glutamate carboxypeptidase
chr19_+_61202902	0.123	NM_153447	NLRP5	NLR family, pyrin domain containing 5
chr14_+_72594940	0.123	NM_021239	RBM25	RNA binding motif protein 25
chr7_-_158304062	0.120		ESYT2	extended synaptotagmin-like protein 2
chr1_-_242073094	0.119	NM_005465 NM_181690	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
chr20_-_34102250	0.119		LOC647979	hypothetical LOC647979
chr6_+_118976134	0.119	NM_002667	PLN	phospholamban
chr2_+_17585462	0.118		VSNL1	visinin-like 1
chr7_-_86686754	0.118	NM_024315	C7orf23	chromosome 7 open reading frame 23
chr8_-_143805371	0.117		LOC100288181	hypothetical LOC100288181
chr6_-_32251877	0.116	NM_006411	AGPAT1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
5.07	5.13e-03	GO:0009615	response to virus
2.41	8.47e-03	GO:0051704	multi-organism process
2.27	1.86e-02	GO:0009892	negative regulation of metabolic process
6.67	2.84e-02	GO:0031575	mitotic cell cycle G1/S transition checkpoint
6.67	2.84e-02	GO:0071779	G1/S transition checkpoint
2.30	2.86e-02	GO:0010605	negative regulation of macromolecule metabolic process
4.65	2.91e-02	GO:0010498	proteasomal protein catabolic process
4.65	2.91e-02	GO:0043161	proteasomal ubiquitin-dependent protein catabolic process
2.37	3.46e-02	GO:0006508	proteolysis
38.99	3.83e-02	GO:0002483	antigen processing and presentation of endogenous peptide antigen
38.99	3.83e-02	GO:0019885	antigen processing and presentation of endogenous peptide antigen via MHC class I
38.99	3.83e-02	GO:0051552	flavone metabolic process
6.34	4.09e-02	GO:2000045	regulation of G1/S transition of mitotic cell cycle
4.89	4.36e-02	GO:0010565	regulation of cellular ketone metabolic process
7.46	4.40e-02	GO:0006977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
7.46	4.40e-02	GO:0072395	signal transduction involved in cell cycle checkpoint
7.46	4.40e-02	GO:0072401	signal transduction involved in DNA integrity checkpoint
7.46	4.40e-02	GO:0072404	signal transduction involved in G1/S transition checkpoint
7.46	4.40e-02	GO:0072413	signal transduction involved in mitotic cell cycle checkpoint
7.46	4.40e-02	GO:0072422	signal transduction involved in DNA damage checkpoint
7.46	4.40e-02	GO:0072431	signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
7.46	4.40e-02	GO:0072474	signal transduction involved in mitotic cell cycle G1/S checkpoint
7.34	4.89e-02	GO:0060337	type I interferon-mediated signaling pathway
7.34	4.89e-02	GO:0071357	cellular response to type I interferon

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
7.22	9.31e-03	GO:0000502	proteasome complex
13.00	4.08e-02	GO:0005839	proteasome core complex
64.98	4.41e-02	GO:0071797	LUBAC complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
20.00	8.48e-03	GO:0001530	lipopolysaccharide binding