Motif ID: SP1.p2

Z-value: 2.777


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SP1chr12_+_520601910.467.2e-02Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr22_+_20101661 5.750 NM_015094
HIC2
hypermethylated in cancer 2
chr6_+_37245860 4.766 NM_002648
PIM1
pim-1 oncogene
chr17_+_78630793 3.995 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr6_+_43846735 3.584 VEGFA
vascular endothelial growth factor A
chr17_+_77582774 3.580 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr9_+_132961723 3.566 AIF1L
allograft inflammatory factor 1-like
chr20_+_30410447 3.260 ASXL1
additional sex combs like 1 (Drosophila)
chr20_+_32045386 3.253 NM_007367
NM_016732
RALY

RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))

chr7_+_73506333 3.195 NM_005685
GTF2IRD1
GTF2I repeat domain containing 1
chr20_+_254205 3.180 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr22_-_19122107 3.064 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr20_+_32045214 3.049 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr2_+_10101081 2.978 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr20_+_32045087 2.977 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr1_+_945331 2.915 NM_198576
AGRN
agrin
chr1_+_167342149 2.894 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_59064795 2.879 MYADM
myeloid-associated differentiation marker
chr7_+_73506172 2.872 GTF2IRD1
GTF2I repeat domain containing 1
chr5_+_139008667 2.867 CXXC5
CXXC finger protein 5
chr22_+_21742364 2.840 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr19_+_50041424 2.828 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr17_+_75849221 2.798 NM_020914
NM_020954
RNF213

ring finger protein 213

chr19_+_540849 2.773 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr20_+_32045203 2.746 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr22_+_21742727 2.719 GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr6_+_43846155 2.716 VEGFA
vascular endothelial growth factor A
chr16_+_87765661 2.709 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr1_+_945399 2.687


chr17_-_76622967 2.684 FLJ90757
hypothetical LOC440465
chr12_+_110328126 2.590 NM_005475
SH2B3
SH2B adaptor protein 3
chr9_+_132961683 2.582 NM_001185095
NM_001185096
NM_031426
AIF1L


allograft inflammatory factor 1-like


chr20_+_34357604 2.519 DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr11_-_133786935 2.475 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr17_+_76623553 2.461 BAIAP2
BAI1-associated protein 2
chr19_+_59064471 2.459 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr21_+_44699796 2.458 NM_030891
LRRC3
leucine rich repeat containing 3
chr1_+_945472 2.452 AGRN
agrin
chr20_+_34523231 2.445 NM_001042486
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chr19_+_8180179 2.444 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr20_+_32045319 2.406 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr22_-_19122047 2.401 SCARF2
scavenger receptor class F, member 2
chr22_-_18635614 2.393 NM_023004
RTN4R
reticulon 4 receptor
chr16_+_1143241 2.390 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr7_+_150414704 2.388 NM_001042535
NM_031946
AGAP3

ArfGAP with GTPase domain, ankyrin repeat and PH domain 3

chr6_-_15356865 2.388


chr22_+_19649417 2.387 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr20_+_60246972 2.387 NM_014835
NM_144498
OSBPL2

oxysterol binding protein-like 2

chr16_+_49139694 2.377 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr19_+_50041400 2.368 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr2_-_74915722 2.354


chrX_+_138060 2.349 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr19_-_55914837 2.347


chr20_+_32045541 2.323 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr22_+_18081968 2.293 NM_002688
SEPT5
septin 5
chr1_+_116717552 2.286 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr12_+_130945215 2.286 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr21_+_45649719 2.283


chr19_+_3045528 2.274 GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr18_+_3439972 2.266 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr19_+_1220244 2.261 NM_001280
CIRBP
cold inducible RNA binding protein
chr20_+_60898249 2.243 NM_018270
C20orf20
chromosome 20 open reading frame 20
chr1_+_224317030 2.242 H3F3A
H3 histone, family 3A
chr3_+_38470782 2.226 NM_001106
ACVR2B
activin A receptor, type IIB
chr1_+_3679168 2.225 NM_001163724
LOC388588
hypothetical protein LOC388588
chr1_+_224317056 2.220 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr7_+_73506047 2.212 NM_016328
GTF2IRD1
GTF2I repeat domain containing 1
chr2_+_86521781 2.205 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr19_+_50041232 2.196 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr17_+_76623540 2.195 NM_001144888
NM_006340
NM_017450
NM_017451
BAIAP2



BAI1-associated protein 2



chr19_-_51829778 2.171 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr16_+_87047159 2.165 ZFPM1
zinc finger protein, multitype 1
chr19_+_50041387 2.163 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr1_+_210848763 2.142 ATF3
activating transcription factor 3
chr22_+_21852743 2.141 BCR
breakpoint cluster region
chr2_+_86521939 2.135 KDM3A
lysine (K)-specific demethylase 3A
chr1_+_220857774 2.130 NM_198551
MIA3
melanoma inhibitory activity family, member 3
chr2_+_218972963 2.129 NM_182642
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_3310138 2.112 NM_205843
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr20_+_32045347 2.100 RALY
RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))
chr19_-_7840806 2.091 FLJ22184
hypothetical protein FLJ22184
chr9_+_129962292 2.080 NM_024112
C9orf16
chromosome 9 open reading frame 16
chr6_+_15357013 2.071 JARID2
jumonji, AT rich interactive domain 2
chr1_+_15123165 2.044 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr20_+_60246971 2.041 OSBPL2
oxysterol binding protein-like 2
chr17_-_73694669 2.028 NM_003258
TK1
thymidine kinase 1, soluble
chr20_+_60246982 2.024 OSBPL2
oxysterol binding protein-like 2
chr16_+_87047418 2.013 NM_153813
ZFPM1
zinc finger protein, multitype 1
chr1_+_224317062 2.000 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr11_-_565848 1.998 LOC143666
hypothetical LOC143666
chr6_+_41622267 1.988 FOXP4
forkhead box P4
chr9_-_137938778 1.978 NM_015447
CAMSAP1
calmodulin regulated spectrin-associated protein 1
chr22_+_19649460 1.973 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr7_+_2638156 1.964 TTYH3
tweety homolog 3 (Drosophila)
chr1_-_3437834 1.954 MEGF6
multiple EGF-like-domains 6
chr16_+_84202515 1.954 NM_001134473
KIAA0182
KIAA0182
chr1_+_224317036 1.939 NM_002107
H3F3A
H3 histone, family 3A
chr16_+_1143738 1.929 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr18_+_75895333 1.920 NM_001171967
NM_024805
RBFA

ribosome binding factor A (putative)

chr2_+_238265617 1.890 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr1_+_116717461 1.882 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr22_+_21817512 1.876 NM_004914
RAB36
RAB36, member RAS oncogene family
chr20_-_34635091 1.869


chr11_+_67836575 1.868 NM_002335
LRP5
low density lipoprotein receptor-related protein 5
chr21_+_42946719 1.863 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr21_+_31953803 1.861 NM_000454
SOD1
superoxide dismutase 1, soluble
chr19_+_2220515 1.860 NM_004152
OAZ1
SPPL2B
ornithine decarboxylase antizyme 1
signal peptide peptidase-like 2B
chr21_+_45649429 1.844 NM_130445
COL18A1
collagen, type XVIII, alpha 1
chr17_-_53946899 1.839 MTMR4
myotubularin related protein 4
chr1_-_113059396 1.823 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr20_+_30409649 1.821 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr19_+_4920126 1.820 KDM4B
lysine (K)-specific demethylase 4B
chr19_+_3045266 1.808 NM_002067
GNA11
guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
chr5_+_139008052 1.801 CXXC5
CXXC finger protein 5
chr1_-_3517918 1.790 NM_001409
MEGF6
multiple EGF-like-domains 6
chr1_+_210848592 1.779 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr22_+_17337970 1.767 DGCR5
DiGeorge syndrome critical region gene 5 (non-protein coding)
chr7_+_36159300 1.759 NM_030636
EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr18_-_75894902 1.756


chr20_+_34635362 1.742 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr2_+_238265519 1.740 NM_001137551
NM_001137552
NM_001137553
NM_004735
LRRFIP1



leucine rich repeat (in FLII) interacting protein 1



chr19_+_4920123 1.739 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr6_+_3204184 1.738 PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr20_+_56899904 1.735 GNAS
GNAS complex locus
chr6_-_31890765 1.735 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr20_-_61574259 1.734 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr10_+_82204054 1.714 TSPAN14
tetraspanin 14
chr20_+_56989717 1.707 TH1L
TH1-like (Drosophila)
chr19_+_7891193 1.705 NM_003083
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr9_+_138497767 1.704 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr14_+_23633101 1.702 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr1_-_6468108 1.700 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_50311666 1.689 NM_012191
NM_003549
NAT6
HYAL3
N-acetyltransferase 6 (GCN5-related)
hyaluronoglucosaminidase 3
chr6_+_138230045 1.682 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr19_+_40183065 1.675 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr17_+_75366524 1.660 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr19_-_7896974 1.659 NM_206833
CTXN1
cortexin 1
chr1_-_6480058 1.650 NM_001042663
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_+_82204046 1.645 TSPAN14
tetraspanin 14
chr19_+_7566698 1.643 NM_001080429
NM_020902
KIAA1543

KIAA1543

chr2_+_238265791 1.638 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr2_+_8739563 1.633 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr19_+_2220529 1.631 OAZ1
ornithine decarboxylase antizyme 1
chr10_+_82204051 1.630 TSPAN14
tetraspanin 14
chr11_+_2422747 1.629 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr1_-_6480035 1.628 PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr6_-_31805547 1.624 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_-_20685314 1.619 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_+_4657352 1.613 NM_002663
PLD2
phospholipase D2
chr9_+_136358134 1.609 NM_002957
RXRA
retinoid X receptor, alpha
chr19_+_2220526 1.609 OAZ1
ornithine decarboxylase antizyme 1
chr22_+_18085891 1.608 SEPT5
septin 5
chr20_+_56989690 1.607 NM_198976
TH1L
TH1-like (Drosophila)
chr22_+_43476755 1.606 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr19_+_59062962 1.604 MYADM
myeloid-associated differentiation marker
chr6_-_31806012 1.600 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_+_224317044 1.600 H3F3A
LOC440926
H3 histone, family 3A
H3 histone, family 3A pseudogene
chr1_+_204924931 1.599 MAPKAPK2
mitogen-activated protein kinase-activated protein kinase 2
chr6_+_3204133 1.597 NM_001128591
NM_001128592
NM_001135750
PSMG4


proteasome (prosome, macropain) assembly chaperone 4


chr22_+_18085990 1.597 SEPT5-GP1BB
SEPT5
SEPT5-GP1BB read-through transcript
septin 5
chr1_-_6468600 1.587 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr19_+_59062982 1.586 MYADM
myeloid-associated differentiation marker
chr16_+_2504001 1.576 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr7_+_36159369 1.572 EEPD1
endonuclease/exonuclease/phosphatase family domain containing 1
chr20_+_48781457 1.570 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr11_-_33678861 1.562 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr4_+_3046034 1.560 NM_002111
HTT
huntingtin
chr20_+_56899867 1.560 GNAS
GNAS complex locus
chr6_+_33046636 1.560 NM_001113182
BRD2
bromodomain containing 2
chr6_+_15353681 1.559 JARID2
jumonji, AT rich interactive domain 2
chr1_-_2115950 1.556 NM_182533
C1orf86
chromosome 1 open reading frame 86
chr2_-_108517028 1.555 FLJ38668
hypothetical LOC644903
chr2_+_10101822 1.554 NM_001177718
KLF11
Kruppel-like factor 11
chr20_+_56900116 1.552 NM_001077488
GNAS
GNAS complex locus
chr11_+_63829616 1.549 NM_004451
ESRRA
estrogen-related receptor alpha
chr1_+_46485946 1.541 NM_001142548
NM_003579
RAD54L

RAD54-like (S. cerevisiae)

chr9_+_136358145 1.534 RXRA
retinoid X receptor, alpha
chr10_-_80875097 1.522 NM_153367
ZCCHC24
zinc finger, CCHC domain containing 24
chr1_-_6402467 1.514 NM_019089
HES2
hairy and enhancer of split 2 (Drosophila)
chr15_+_73923047 1.512 UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr19_-_43570503 1.508 NM_152657
GGN
gametogenetin
chr17_+_34279781 1.506 LASP1
LIM and SH3 protein 1
chr22_-_20419975 1.505 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr5_+_56505608 1.501 GPBP1
GC-rich promoter binding protein 1
chr6_+_33046706 1.500 BRD2
bromodomain containing 2
chr22_+_21852699 1.498 BCR
breakpoint cluster region
chr19_+_7891884 1.490 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr2_+_108517239 1.489 NM_001193483
LIMS1
LIM and senescent cell antigen-like domains 1
chr2_+_30223372 1.482 YPEL5
yippee-like 5 (Drosophila)
chr20_+_60130866 1.481 NM_144703
LSM14B
LSM14B, SCD6 homolog B (S. cerevisiae)
chr6_-_31805932 1.477 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr20_+_35407872 1.476 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr9_-_138497324 1.471 NM_014866
SEC16A
SEC16 homolog A (S. cerevisiae)
chr2_+_86521999 1.470 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr18_+_27925923 1.468 RNF138
ring finger protein 138
chr9_+_135314907 1.463 NM_001135775
NM_017586
C9orf7

chromosome 9 open reading frame 7

chr17_+_34279637 1.462 NM_006148
LASP1
LIM and SH3 protein 1
chr16_+_2503915 1.461 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr17_+_34279877 1.461 LASP1
LIM and SH3 protein 1
chr5_+_139008139 1.459 CXXC5
CXXC finger protein 5
chr6_+_37895570 1.459 ZFAND3
zinc finger, AN1-type domain 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 4.36e-28 GO:0009987 cellular process
1.13 1.91e-20 GO:0044237 cellular metabolic process
1.10 8.19e-20 GO:0065007 biological regulation
1.11 1.05e-19 GO:0050789 regulation of biological process
1.11 3.53e-18 GO:0050794 regulation of cellular process
1.15 8.64e-17 GO:0044260 cellular macromolecule metabolic process
1.14 4.84e-13 GO:0019222 regulation of metabolic process
1.10 4.97e-13 GO:0044238 primary metabolic process
1.16 5.02e-13 GO:0060255 regulation of macromolecule metabolic process
1.15 1.12e-12 GO:0031323 regulation of cellular metabolic process
1.15 3.17e-12 GO:0080090 regulation of primary metabolic process
1.09 3.22e-12 GO:0008152 metabolic process
1.17 6.05e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 1.28e-11 GO:0010468 regulation of gene expression
1.18 1.55e-11 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.11 9.60e-11 GO:0043170 macromolecule metabolic process
1.15 1.06e-10 GO:0034641 cellular nitrogen compound metabolic process
1.17 1.76e-10 GO:0010556 regulation of macromolecule biosynthetic process
1.14 1.86e-10 GO:0006807 nitrogen compound metabolic process
1.16 8.50e-10 GO:0031326 regulation of cellular biosynthetic process
1.16 1.55e-09 GO:0009889 regulation of biosynthetic process
1.17 2.91e-09 GO:0051252 regulation of RNA metabolic process
1.17 1.39e-08 GO:0006355 regulation of transcription, DNA-dependent
1.19 1.97e-08 GO:0016070 RNA metabolic process
1.19 2.68e-08 GO:0034645 cellular macromolecule biosynthetic process
1.16 2.85e-08 GO:0090304 nucleic acid metabolic process
1.27 5.30e-08 GO:0006351 transcription, DNA-dependent
1.14 6.07e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.15 6.93e-08 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.15 7.59e-08 GO:0044249 cellular biosynthetic process
1.18 9.22e-08 GO:0010467 gene expression
1.19 1.06e-07 GO:0009059 macromolecule biosynthetic process
1.15 4.62e-07 GO:0048519 negative regulation of biological process
1.14 4.80e-07 GO:0071842 cellular component organization at cellular level
1.14 4.95e-07 GO:0071841 cellular component organization or biogenesis at cellular level
1.24 5.69e-07 GO:0032774 RNA biosynthetic process
1.14 6.42e-07 GO:0009058 biosynthetic process
1.12 1.75e-06 GO:0016043 cellular component organization
1.11 2.08e-06 GO:0071840 cellular component organization or biogenesis
1.15 2.54e-06 GO:0048523 negative regulation of cellular process
1.13 7.86e-06 GO:0048518 positive regulation of biological process
1.10 2.09e-05 GO:0023052 signaling
1.22 7.53e-05 GO:0010605 negative regulation of macromolecule metabolic process
1.10 1.08e-04 GO:0007165 signal transduction
1.12 1.20e-04 GO:0044267 cellular protein metabolic process
1.09 1.50e-04 GO:0051716 cellular response to stimulus
1.16 1.71e-04 GO:0006996 organelle organization
1.16 1.93e-04 GO:0007399 nervous system development
1.20 2.40e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.09 3.20e-04 GO:0032502 developmental process
1.19 3.42e-04 GO:0007049 cell cycle
1.10 3.78e-04 GO:0007275 multicellular organismal development
1.13 3.90e-04 GO:0065008 regulation of biological quality
1.12 3.99e-04 GO:0048522 positive regulation of cellular process
1.25 4.45e-04 GO:0010629 negative regulation of gene expression
1.10 4.76e-04 GO:0051179 localization
1.20 4.99e-04 GO:0009892 negative regulation of metabolic process
1.18 5.46e-04 GO:0044248 cellular catabolic process
1.16 1.56e-03 GO:0051641 cellular localization
1.17 1.81e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.18 1.81e-03 GO:0032268 regulation of cellular protein metabolic process
1.19 4.25e-03 GO:0008219 cell death
1.19 4.26e-03 GO:0022008 neurogenesis
1.16 4.99e-03 GO:0009893 positive regulation of metabolic process
1.17 5.09e-03 GO:0051246 regulation of protein metabolic process
1.22 6.05e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.20 6.38e-03 GO:0022402 cell cycle process
1.19 8.57e-03 GO:0016265 death
1.24 9.09e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.25 9.16e-03 GO:0072358 cardiovascular system development
1.25 9.16e-03 GO:0072359 circulatory system development
1.29 9.48e-03 GO:0016568 chromatin modification
1.15 1.01e-02 GO:0033036 macromolecule localization
1.18 1.09e-02 GO:0031324 negative regulation of cellular metabolic process
1.22 1.48e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.15 1.59e-02 GO:0031325 positive regulation of cellular metabolic process
1.14 1.67e-02 GO:0009653 anatomical structure morphogenesis
1.13 1.81e-02 GO:0023051 regulation of signaling
1.10 2.15e-02 GO:0048731 system development
1.23 2.16e-02 GO:0051253 negative regulation of RNA metabolic process
1.12 2.39e-02 GO:0006464 protein modification process
1.20 2.60e-02 GO:0009890 negative regulation of biosynthetic process
1.25 2.94e-02 GO:0048812 neuron projection morphogenesis
1.29 3.09e-02 GO:0007411 axon guidance
1.19 3.28e-02 GO:0012501 programmed cell death
1.19 3.43e-02 GO:0006915 apoptosis
1.25 3.70e-02 GO:0007409 axonogenesis
1.09 4.04e-02 GO:0048856 anatomical structure development
1.09 4.31e-02 GO:0051234 establishment of localization
1.23 4.46e-02 GO:0031175 neuron projection development
1.13 4.55e-02 GO:0009056 catabolic process
1.26 4.62e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.15 4.80e-02 GO:0008104 protein localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 4.99e-47 GO:0005622 intracellular
1.10 2.14e-46 GO:0044424 intracellular part
1.10 1.20e-35 GO:0043229 intracellular organelle
1.10 2.79e-35 GO:0043226 organelle
1.11 1.16e-34 GO:0043227 membrane-bounded organelle
1.11 1.70e-34 GO:0043231 intracellular membrane-bounded organelle
1.14 3.54e-23 GO:0005634 nucleus
1.10 7.57e-23 GO:0005737 cytoplasm
1.11 2.21e-15 GO:0044444 cytoplasmic part
1.11 5.20e-15 GO:0044446 intracellular organelle part
1.11 1.09e-14 GO:0044422 organelle part
1.03 5.50e-14 GO:0044464 cell part
1.03 6.45e-14 GO:0005623 cell
1.19 8.59e-13 GO:0044428 nuclear part
1.20 2.92e-12 GO:0031981 nuclear lumen
1.18 3.00e-11 GO:0070013 intracellular organelle lumen
1.17 5.91e-11 GO:0031974 membrane-enclosed lumen
1.17 9.07e-11 GO:0043233 organelle lumen
1.17 2.10e-09 GO:0005829 cytosol
1.21 2.78e-09 GO:0005654 nucleoplasm
1.13 6.34e-08 GO:0043234 protein complex
1.10 7.47e-06 GO:0032991 macromolecular complex
1.16 8.02e-06 GO:0012505 endomembrane system
1.24 2.42e-05 GO:0015630 microtubule cytoskeleton
1.13 8.21e-05 GO:0031090 organelle membrane
1.20 1.65e-03 GO:0044451 nucleoplasm part
1.29 5.11e-03 GO:0005874 microtubule
1.15 9.70e-03 GO:0005783 endoplasmic reticulum
1.26 1.65e-02 GO:0005815 microtubule organizing center
1.47 4.38e-02 GO:0016585 chromatin remodeling complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.07 7.21e-30 GO:0005488 binding
1.12 9.67e-27 GO:0005515 protein binding
1.14 1.38e-11 GO:0003676 nucleic acid binding
1.16 6.78e-10 GO:0003677 DNA binding
1.15 2.72e-08 GO:0046914 transition metal ion binding
1.16 8.95e-08 GO:0008270 zinc ion binding
1.11 3.29e-07 GO:0046872 metal ion binding
1.22 6.78e-07 GO:0001071 nucleic acid binding transcription factor activity
1.22 6.78e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.10 8.46e-07 GO:0043169 cation binding
1.10 8.80e-07 GO:0043167 ion binding
1.14 3.25e-06 GO:0000166 nucleotide binding
1.20 2.39e-05 GO:0030528 transcription regulator activity
1.14 3.69e-05 GO:0032553 ribonucleotide binding
1.14 3.69e-05 GO:0032555 purine ribonucleotide binding
1.14 4.55e-05 GO:0017076 purine nucleotide binding
1.07 7.88e-05 GO:0003824 catalytic activity
1.13 2.73e-04 GO:0035639 purine ribonucleoside triphosphate binding
1.33 3.66e-04 GO:0016564 transcription repressor activity
1.24 1.64e-03 GO:0008092 cytoskeletal protein binding
1.63 2.11e-03 GO:0042393 histone binding
1.13 3.98e-03 GO:0032559 adenyl ribonucleotide binding
1.13 4.88e-03 GO:0030554 adenyl nucleotide binding
1.36 1.78e-02 GO:0003682 chromatin binding
1.46 1.81e-02 GO:0015631 tubulin binding
1.12 2.13e-02 GO:0005524 ATP binding