Motif ID: POU5F1.p2

Z-value: 0.850


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU5F1chr6_-_31246159-0.165.5e-01Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_33267646 1.629 NM_000109
DMD
dystrophin
chr9_-_14076901 1.366 NFIB
nuclear factor I/B
chr1_-_215329569 0.930 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr3_+_174598937 0.783 NM_014932
NLGN1
neuroligin 1
chr5_-_27074407 0.775 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr2_+_108751033 0.674 RANBP2
RAN binding protein 2
chr4_-_110443247 0.665 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr12_-_16649211 0.662 LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_-_35428848 0.654 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr2_-_50428395 0.651 NM_138735
NRXN1
neurexin 1
chr14_+_78815406 0.610 NM_001105250
NM_138970
NRXN3

neurexin 3

chr13_-_101852028 0.603 NM_175929
FGF14
fibroblast growth factor 14
chr2_-_210726539 0.600 C2orf67
chromosome 2 open reading frame 67
chr1_+_172683834 0.581 NM_005684
GPR52
G protein-coupled receptor 52
chr3_-_193928038 0.575 NM_004113
FGF12
fibroblast growth factor 12
chr9_-_85773899 0.575 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr15_+_26832300 0.556 LOC100289656
Dexi homolog (mouse) pseudogene
chr3_+_129124591 0.549 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr12_-_11178109 0.547 NM_001097643
TAS2R30
taste receptor, type 2, member 30
chrX_-_15312390 0.546 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chrX_-_123925343 0.537 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr3_-_152173475 0.529 NM_001195794
NM_174878
CLRN1

clarin 1

chr1_+_168381811 0.519 NM_001136107
METTL11B
methyltransferase like 11B
chr3_+_51837608 0.514 NM_001085479
IQCF3
IQ motif containing F3
chr16_+_24475129 0.512 RBBP6
retinoblastoma binding protein 6
chr3_-_79899748 0.510 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr12_-_7709734 0.494 NM_001644
APOBEC1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr18_+_75968133 0.489 ADNP2
ADNP homeobox 2
chrX_+_72583814 0.486 NM_005193
CDX4
caudal type homeobox 4
chr11_-_34336102 0.477 NM_145804
ABTB2
ankyrin repeat and BTB (POZ) domain containing 2
chr2_+_214984705 0.456 NM_001080500
VWC2L
von Willebrand factor C domain containing protein 2-like
chr4_-_174774368 0.455 NM_006792
MORF4
mortality factor 4
chr10_-_37931864 0.452 NM_001190489
MTRNR2L7
MT-RNR2-like 7
chr17_-_36232366 0.444 NM_000421
KRT10
keratin 10
chr6_-_128263868 0.443 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr14_-_106184988 0.442 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_-_16717887 0.433 BNC2
basonuclin 2
chr10_+_124135574 0.427 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_145479805 0.426 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr3_-_64186151 0.418 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr2_-_165259334 0.410 COBLL1
COBL-like 1
chr14_-_105997732 0.409 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_51112743 0.409 NRXN1
neurexin 1
chr1_+_116727514 0.403 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr10_+_51246290 0.400 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr10_+_104525877 0.396 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr22_+_28806452 0.391 NM_152510
HORMAD2
HORMA domain containing 2
chr4_+_184257337 0.386 NM_024949
WWC2
WW and C2 domain containing 2
chr1_-_102234959 0.385 OLFM3
olfactomedin 3
chr2_+_114935623 0.383 NM_001178036
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr5_+_54491702 0.382 NM_001008397
GPX8
glutathione peroxidase 8 (putative)
chr11_-_49960646 0.372 NM_001005270
OR4C12
olfactory receptor, family 4, subfamily C, member 12
chr3_-_18455207 0.366 NM_001131010
SATB1
SATB homeobox 1
chrX_-_6156655 0.366 NM_181332
NLGN4X
neuroligin 4, X-linked
chr9_+_112470871 0.363 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr3_+_99334230 0.355 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr14_-_33489708 0.354 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr3_-_133236447 0.352 NM_130808
CPNE4
copine IV
chr13_-_69580459 0.351 NM_020866
KLHL1
kelch-like 1 (Drosophila)
chr5_-_160211623 0.349 NM_025153
ATP10B
ATPase, class V, type 10B
chr2_+_89715037 0.349


chr5_-_36337756 0.348 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr13_+_96797290 0.348


chr12_+_14409875 0.348 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr2_-_36929520 0.347 STRN
striatin, calmodulin binding protein
chr15_+_55298908 0.340 NM_207040
TCF12
transcription factor 12
chr4_-_91979113 0.340 NM_183049
TMSL3
thymosin-like 3
chr3_+_88270951 0.340 NM_018293
ZNF654
zinc finger protein 654
chr13_-_85271329 0.338 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_166397142 0.337 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr20_-_604822 0.337 NM_033129
SCRT2
scratch homolog 2, zinc finger protein (Drosophila)
chr6_+_53043729 0.330 NM_012347
FBXO9
F-box protein 9
chr15_-_70288071 0.330 PKM2
pyruvate kinase, muscle
chr2_-_40593074 0.328 NM_001112802
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr2_-_200038055 0.327 NM_001172517
SATB2
SATB homeobox 2
chr4_+_73116384 0.325 NM_004885
NPFFR2
neuropeptide FF receptor 2
chr10_-_21847126 0.322


chr11_-_56067308 0.322 NM_001005245
OR5M11
olfactory receptor, family 5, subfamily M, member 11
chr6_+_88021644 0.320 ZNF292
zinc finger protein 292
chr19_-_45253947 0.318 NM_001005851
ZNF780B
zinc finger protein 780B
chr1_+_107485071 0.318 NTNG1
netrin G1
chr6_+_45404031 0.317 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chrX_-_77801480 0.317 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr5_-_39238818 0.316 FYB
FYN binding protein
chr4_-_184480572 0.316 NM_001185149
CLDN24
claudin 24
chr14_-_105948734 0.315 LOC100126583
IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr5_-_43326922 0.314 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr1_+_191044791 0.314 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr2_+_189547358 0.313 COL3A1
collagen, type III, alpha 1
chrX_-_105169370 0.311 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr13_-_60887210 0.309 PCDH20
protocadherin 20
chrX_-_24575375 0.308 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr11_-_114880275 0.307 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_+_190811479 0.302 NM_002922
RGS1
regulator of G-protein signaling 1
chr14_-_106352471 0.301


chr2_+_102456193 0.300 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr4_+_124540114 0.299 NM_005841
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr1_-_151296611 0.297 NM_005988
SPRR2A
small proline-rich protein 2A
chr4_-_163304567 0.296 NM_001128427
NM_001128428
NM_020116
FSTL5


follistatin-like 5


chr14_-_106064887 0.296 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr14_+_61532293 0.294 NM_031914
SYT16
synaptotagmin XVI
chr2_-_210744158 0.293 NM_152519
C2orf67
chromosome 2 open reading frame 67
chr7_-_38915306 0.286 NM_014396
NM_080631
VPS41

vacuolar protein sorting 41 homolog (S. cerevisiae)

chr5_+_140411144 0.286 NM_013340
PCDHB1
protocadherin beta 1
chr4_-_116254381 0.284 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr3_+_189413414 0.283 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr3_+_99370233 0.282 NM_001005515
OR5H15
olfactory receptor, family 5, subfamily H, member 15
chrX_-_106846924 0.282 NM_004089
TSC22D3
TSC22 domain family, member 3
chr20_-_39680405 0.282 NM_032221
CHD6
chromodomain helicase DNA binding protein 6
chrX_-_106846684 0.281 TSC22D3
TSC22 domain family, member 3
chr1_+_162795328 0.280 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr11_-_51269023 0.279 NM_001005272
OR4A5
olfactory receptor, family 4, subfamily A, member 5
chr5_-_146238336 0.279 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr1_-_151280201 0.278 NM_006945
SPRR2D
small proline-rich protein 2D
chr5_-_54317102 0.278 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr14_-_106193403 0.278 IGKV3-20
immunoglobulin kappa variable 3-20
chr2_-_191580567 0.278 STAT1
signal transducer and activator of transcription 1, 91kDa
chrX_-_43717864 0.277 NM_000266
NDP
Norrie disease (pseudoglioma)
chr18_+_75967902 0.273 NM_014913
ADNP2
ADNP homeobox 2
chr20_+_55569542 0.272 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr18_+_57308754 0.272 NM_031891
CDH20
cadherin 20, type 2
chr12_+_54231249 0.271 NM_001005494
OR6C4
olfactory receptor, family 6, subfamily C, member 4
chr1_+_190871868 0.270 NM_002927
NM_144766
RGS13

regulator of G-protein signaling 13

chrX_+_50670474 0.269 NM_005448
BMP15
bone morphogenetic protein 15
chr14_-_105785639 0.267


chr14_-_105644300 0.267 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr14_-_106249999 0.267 IGHA1
immunoglobulin heavy constant alpha 1
chr1_-_118529303 0.267 NM_206996
SPAG17
sperm associated antigen 17
chr3_-_58497913 0.265 NM_003500
ACOX2
acyl-CoA oxidase 2, branched chain
chr3_-_78749633 0.265 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr10_-_108448990 0.264 SORCS1
sortilin-related VPS10 domain containing receptor 1
chrX_-_32340291 0.263 NM_004011
NM_004012
DMD

dystrophin

chr14_-_106149623 0.263


chr10_+_115302767 0.260 NM_004132
HABP2
hyaluronan binding protein 2
chr2_-_215953818 0.259 FN1
fibronectin 1
chr14_-_105862080 0.258 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr8_-_23768242 0.258 NM_003155
STC1
stanniocalcin 1
chr1_-_181889070 0.255 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr11_+_62813947 0.255 NM_001039752
SLC22A10
solute carrier family 22, member 10
chr14_-_19553191 0.254 NM_001004712
OR4K14
olfactory receptor, family 4, subfamily K, member 14
chr4_+_70831387 0.252 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chr14_-_19572756 0.251 NM_001004714
OR4K13
olfactory receptor, family 4, subfamily K, member 13
chr7_+_142590633 0.251 NM_176881
TAS2R39
taste receptor, type 2, member 39
chr3_-_102194938 0.251 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr16_+_52081836 0.249 RBL2
retinoblastoma-like 2 (p130)
chrX_-_130792297 0.248 LOC286467
hypothetical LOC286467
chr2_-_119322228 0.247 NM_001426
EN1
engrailed homeobox 1
chr3_+_99465777 0.246 NM_001005479
OR5H6
olfactory receptor, family 5, subfamily H, member 6
chr12_-_6642513 0.246 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr2_+_196229715 0.245 NM_001127257
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr11_-_107969554 0.245 NM_015065
EXPH5
exophilin 5
chr10_+_95507555 0.244 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr7_+_141342147 0.244 NM_004668
MGAM
maltase-glucoamylase (alpha-glucosidase)
chr1_+_103999824 0.243 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr11_-_26700121 0.242 NM_178498
SLC5A12
solute carrier family 5 (sodium/glucose cotransporter), member 12
chr7_-_31347032 0.242 NM_022728
NEUROD6
neurogenic differentiation 6
chr2_-_165768798 0.241 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr10_-_121592020 0.241 MCMBP
minichromosome maintenance complex binding protein
chr10_+_90414125 0.241 NM_001198828
NM_001198829
NM_001198830
NM_004190
LIPF



lipase, gastric



chr8_+_104900591 0.240 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr2_+_189547377 0.240 COL3A1
collagen, type III, alpha 1
chr1_+_200018380 0.239 NAV1
neuron navigator 1
chrX_+_15435351 0.239 NM_001721
BMX
BMX non-receptor tyrosine kinase
chr12_+_10015274 0.237 NM_138337
NM_201623
CLEC12A

C-type lectin domain family 12, member A

chr11_-_83706027 0.236 DLG2
discs, large homolog 2 (Drosophila)
chr2_-_51113040 0.236 NM_001135659
NM_004801
NRXN1

neurexin 1

chr4_-_47534815 0.235 NM_006587
CORIN
corin, serine peptidase
chr4_+_74520796 0.234 NM_001134
AFP
alpha-fetoprotein
chr5_+_52131686 0.234 PELO
pelota homolog (Drosophila)
chr12_-_11066436 0.234 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr11_-_558419 0.232


chr2_+_155263338 0.231 NM_002239
KCNJ3
potassium inwardly-rectifying channel, subfamily J, member 3
chr22_+_31080871 0.231 NM_006604
RFPL3
ret finger protein-like 3
chrX_+_144710557 0.230 NM_001144006
NM_001144008
NM_001144009
NM_001144010
SLITRK2



SLIT and NTRK-like family, member 2



chr14_+_38719462 0.230 PNN
pinin, desmosome associated protein
chr2_-_95846109 0.230 LOC150759
hypothetical LOC150759
chr1_+_145892190 0.229 NM_001097616
GPR89C
G protein-coupled receptor 89C
chr1_+_213245507 0.229 NM_001017424
KCNK2
potassium channel, subfamily K, member 2
chr19_-_58052664 0.228 NM_001008801
NM_199132
ZNF468

zinc finger protein 468

chr21_+_30724442 0.228 NM_181600
KRTAP13-4
keratin associated protein 13-4
chrX_+_16051344 0.228 NM_005314
GRPR
gastrin-releasing peptide receptor
chr6_+_7052798 0.227 NM_001168344
RREB1
ras responsive element binding protein 1
chr14_-_106282128 0.226 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_18033970 0.224 NM_175886
PRPS1L1
phosphoribosyl pyrophosphate synthetase 1-like 1
chr2_-_207738858 0.224 NM_003709
KLF7
Kruppel-like factor 7 (ubiquitous)
chrX_+_2934653 0.222 NM_001011719
ARSH
arylsulfatase family, member H
chr3_-_24511180 0.222 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr6_-_151754337 0.221 NM_020861
ZBTB2
zinc finger and BTB domain containing 2
chr9_+_33016482 0.220 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr8_-_16903911 0.219 NM_019851
FGF20
fibroblast growth factor 20
chr14_-_105681377 0.219 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_146237826 0.218 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr18_+_61568825 0.218 CDH7
cadherin 7, type 2
chr17_-_36276987 0.217 NM_000223
KRT12
keratin 12
chr21_-_26175068 0.217 APP
amyloid beta (A4) precursor protein
chr2_+_211166323 0.217 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr14_+_19761708 0.217 NM_001004480
OR11H6
olfactory receptor, family 11, subfamily H, member 6
chr11_+_58980986 0.216 NM_001004708
OR4D6
olfactory receptor, family 4, subfamily D, member 6
chr18_+_61569136 0.215 NM_004361
CDH7
cadherin 7, type 2
chr2_-_215998181 0.215 FN1
fibronectin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 1.49e-11 GO:0032501 multicellular organismal process
1.36 3.48e-07 GO:0048731 system development
1.51 7.88e-07 GO:0007399 nervous system development
1.97 8.05e-07 GO:0007606 sensory perception of chemical stimulus
1.30 1.75e-06 GO:0007275 multicellular organismal development
1.28 3.78e-06 GO:0032502 developmental process
1.45 4.94e-06 GO:0003008 system process
1.31 5.94e-06 GO:0048856 anatomical structure development
1.49 1.20e-05 GO:0050877 neurological system process
1.64 2.32e-05 GO:0007600 sensory perception
1.18 8.26e-05 GO:0050896 response to stimulus
1.35 3.13e-04 GO:0030154 cell differentiation
1.83 6.05e-04 GO:0007608 sensory perception of smell
1.33 1.08e-03 GO:0048869 cellular developmental process
1.31 1.88e-02 GO:0048513 organ development
1.46 2.77e-02 GO:0022008 neurogenesis
3.37 4.32e-02 GO:0050909 sensory perception of taste
1.44 4.69e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.22 3.30e-05 GO:0071944 cell periphery
1.22 4.20e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.64 2.35e-06 GO:0004930 G-protein coupled receptor activity
1.51 2.67e-06 GO:0004888 transmembrane receptor activity
1.41 9.77e-06 GO:0004872 receptor activity
1.89 4.12e-05 GO:0004984 olfactory receptor activity
1.34 5.90e-05 GO:0004871 signal transducer activity
1.34 5.90e-05 GO:0060089 molecular transducer activity
1.50 2.29e-04 GO:0001071 nucleic acid binding transcription factor activity
1.50 2.29e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
5.79 2.52e-03 GO:0008527 taste receptor activity
1.49 1.93e-02 GO:0043565 sequence-specific DNA binding