Motif ID: ONECUT1,2.p2

Z-value: 1.413


Transcription factors associated with ONECUT1,2.p2:

Gene SymbolEntrez IDGene Name
ONECUT1 3175 one cut homeobox 1
ONECUT2 9480 one cut homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ONECUT2chr18_+_53253775-0.165.5e-01Click!
ONECUT1chr15_-_508693790.039.0e-01Click!


Activity profile for motif ONECUT1,2.p2.

activity profile for motif ONECUT1,2.p2


Sorted Z-values histogram for motif ONECUT1,2.p2

Sorted Z-values for motif ONECUT1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ONECUT1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_110252960 2.087 NM_001128168
NM_001128172
NM_001128173
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr1_-_51660328 1.990 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr1_+_246635918 1.866 NM_030904
OR2T1
olfactory receptor, family 2, subfamily T, member 1
chr1_-_611896 1.716 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chrX_+_100361588 1.532 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr22_+_21384862 1.531 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr5_+_180726874 1.528 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chr12_+_32546243 1.492 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr4_-_20594645 1.392 KCNIP4
Kv channel interacting protein 4
chr14_+_66901237 1.369 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chrX_-_74921704 1.369 NM_138703
MAGEE2
melanoma antigen family E, 2
chr9_-_14076901 1.250 NFIB
nuclear factor I/B
chrX_-_54841397 1.228 NM_198510
ITIH5L
inter-alpha (globulin) inhibitor H5-like
chrX_-_131401319 1.218 NM_018388
NM_133486
MBNL3

muscleblind-like 3 (Drosophila)

chrX_+_106057984 1.215 CLDN2
claudin 2
chr3_+_2528272 1.213 CNTN4
contactin 4
chrX_-_102452461 1.200 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr1_-_150328153 1.132 NM_001008536
TCHHL1
trichohyalin-like 1
chr15_-_100280784 1.121 NM_001004195
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chr11_-_74478405 1.105 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr11_+_62893836 1.060 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr10_+_46503539 1.056 NM_005972
PPYR1
pancreatic polypeptide receptor 1
chr1_+_190871868 1.028 NM_002927
NM_144766
RGS13

regulator of G-protein signaling 13

chr5_+_32824701 1.025 NM_024563
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_146843980 1.020 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chrX_-_32340291 0.994 NM_004011
NM_004012
DMD

dystrophin

chr9_-_21218132 0.966 NM_021268
IFNA17
interferon, alpha 17
chr16_+_65938753 0.963 NM_001161575
LRRC36
leucine rich repeat containing 36
chr6_+_28032997 0.962 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chrX_-_33139349 0.958 NM_004006
DMD
dystrophin
chr19_-_53305825 0.925 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr1_-_21310462 0.919 NM_003760
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_-_24600661 0.907 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr4_+_176076083 0.886 NM_001130703
NM_001130704
NM_001130705
NM_014269
ADAM29



ADAM metallopeptidase domain 29



chrX_-_19898302 0.876 NM_198279
CXorf23
chromosome X open reading frame 23
chr2_+_172530120 0.873 HAT1
histone acetyltransferase 1
chr10_-_72215116 0.869 NM_152710
C10orf27
chromosome 10 open reading frame 27
chr19_-_9087438 0.859 NM_001005192
OR7G1
olfactory receptor, family 7, subfamily G, member 1
chr22_+_21053972 0.857


chr8_+_110168828 0.856 NM_003301
TRHR
thyrotropin-releasing hormone receptor
chrX_+_85404626 0.850 NM_001139515
DACH2
dachshund homolog 2 (Drosophila)
chrX_+_49718954 0.840 NM_000084
CLCN5
chloride channel 5
chr10_+_97749837 0.808 NM_001001732
NM_001159747
CC2D2B

coiled-coil and C2 domain containing 2B

chr5_+_147754467 0.800 FBXO38
F-box protein 38
chr12_-_44919818 0.799 SLC38A1
solute carrier family 38, member 1
chr18_+_52575442 0.792 WDR7
WD repeat domain 7
chr11_+_17289030 0.790


chr7_-_23476497 0.789 NM_006547
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chrX_+_134803450 0.782 NM_018666
SAGE1
sarcoma antigen 1
chr11_+_125208420 0.777 NM_001144874
PATE4
prostate and testis expressed 4
chr6_-_41823056 0.768 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr1_+_143807748 0.761 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chrX_-_33267646 0.760 NM_000109
DMD
dystrophin
chr12_+_21417068 0.755 NM_000415
IAPP
islet amyloid polypeptide
chr6_+_64344307 0.753 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_144374513 0.717 RNF115
ring finger protein 115
chrX_-_10605726 0.716 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr7_+_104539548 0.707 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr11_+_59038961 0.705 NM_001004711
OR4D9
olfactory receptor, family 4, subfamily D, member 9
chrX_-_133620103 0.704 NM_021796
PLAC1
placenta-specific 1
chr1_+_357502 0.703 NM_001005224
NM_001005221
NM_001005277
OR4F3
OR4F29
OR4F16
olfactory receptor, family 4, subfamily F, member 3
olfactory receptor, family 4, subfamily F, member 29
olfactory receptor, family 4, subfamily F, member 16
chrX_+_55760774 0.695 NM_006064
NM_016656
RRAGB

Ras-related GTP binding B

chr5_+_86712376 0.693


chrX_-_43717864 0.690 NM_000266
NDP
Norrie disease (pseudoglioma)
chr1_+_12325632 0.688 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_-_20914626 0.685 NM_147183
KCNIP4
Kv channel interacting protein 4
chr11_+_89624017 0.679


chr1_+_147006065 0.676 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chrX_-_106248674 0.670 RBM41
RNA binding motif protein 41
chr13_+_108046500 0.665 NM_015011
MYO16
myosin XVI
chr5_+_38439399 0.655 NM_182798
NM_182799
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr12_+_54132264 0.640 NM_054105
OR6C2
olfactory receptor, family 6, subfamily C, member 2
chr18_+_27425727 0.629 NM_000371
TTR
transthyretin
chr3_-_188870799 0.626 NM_001048
SST
somatostatin
chr5_+_148711419 0.618 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr21_+_30724442 0.614 NM_181600
KRTAP13-4
keratin associated protein 13-4
chr8_+_118216517 0.611 NM_001172814
NM_173851
SLC30A8

solute carrier family 30 (zinc transporter), member 8

chr3_-_114176401 0.605 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr2_+_130703384 0.605


chr19_+_58239802 0.600 NM_001191055
HERV-V2
envelope glycoprotein ENVV2
chr12_-_89976261 0.597 NM_007035
KERA
keratocan
chr5_-_43448174 0.596 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr3_+_99334230 0.591 NM_001005338
OR5H1
olfactory receptor, family 5, subfamily H, member 1
chr7_+_129057152 0.580 NM_001040110
NRF1
nuclear respiratory factor 1
chr4_-_44348414 0.577 NM_182592
YIPF7
Yip1 domain family, member 7
chr21_+_30886629 0.576 NM_181605
KRTAP6-3
keratin associated protein 6-3
chr8_+_32623792 0.576 NM_013959
NRG1
neuregulin 1
chr8_-_15140162 0.575 NM_139167
SGCZ
sarcoglycan, zeta
chr1_-_67366807 0.573 NM_001013674
C1orf141
chromosome 1 open reading frame 141
chr1_-_215329569 0.569 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr5_-_41107161 0.567 NM_173489
HEATR7B2
HEAT repeat family member 7B2
chrX_+_38096679 0.560 NM_000531
OTC
ornithine carbamoyltransferase
chr1_-_246823691 0.554 NM_001004693
OR2T10
olfactory receptor, family 2, subfamily T, member 10
chrX_+_144710557 0.550 NM_001144006
NM_001144008
NM_001144009
NM_001144010
SLITRK2



SLIT and NTRK-like family, member 2



chr3_-_168580764 0.550 NM_024687
ZBBX
zinc finger, B-box domain containing
chrX_-_64112993 0.550 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr5_-_27074407 0.548 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr1_+_144004589 0.545 NM_001039703
NBPF10
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 8
chrX_-_85189194 0.543 NM_000390
NM_001145414
CHM

choroideremia (Rab escort protein 1)

chr4_+_53975597 0.541 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr6_-_64087806 0.538 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr10_+_95507555 0.532 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr15_+_70477707 0.530 NM_001080462
TMEM202
transmembrane protein 202
chr4_+_69716298 0.525 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr7_+_28441758 0.523 NM_004904
CREB5
cAMP responsive element binding protein 5
chr7_-_92615593 0.521 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr6_-_119137923 0.510 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr6_+_45404031 0.509 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr3_-_64186151 0.508 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_+_62835759 0.508 NM_014495
ANGPTL3
angiopoietin-like 3
chr14_-_60185659 0.503 NM_005982
SIX1
SIX homeobox 1
chr17_-_31219943 0.501 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr5_-_160211623 0.499 NM_025153
ATP10B
ATPase, class V, type 10B
chrX_+_78313124 0.498 NM_032553
GPR174
G protein-coupled receptor 174
chr11_+_123639909 0.496 NM_001005198
OR8G5
olfactory receptor, family 8, subfamily G, member 5
chr7_+_120490054 0.487 C7orf58
chromosome 7 open reading frame 58
chrX_-_119550402 0.486 CUL4B
cullin 4B
chr14_+_19513442 0.485 NM_001005486
OR4K15
olfactory receptor, family 4, subfamily K, member 15
chr9_-_27519434 0.479 NM_024761
MOBKL2B
MOB1, Mps One Binder kinase activator-like 2B (yeast)
chrX_-_76700873 0.477 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr10_-_98280299 0.475 TM9SF3
transmembrane 9 superfamily member 3
chr19_-_47623340 0.471 NM_005357
LIPE
lipase, hormone-sensitive
chr3_-_127760447 0.464 NM_152533
C3orf22
chromosome 3 open reading frame 22
chrX_+_41468351 0.464 NM_080817
GPR82
G protein-coupled receptor 82
chrX_-_106248706 0.462 NM_001171080
NM_018301
RBM41

RNA binding motif protein 41

chr21_-_46849413 0.461 NM_006272
S100B
S100 calcium binding protein B
chr6_+_53043729 0.459 NM_012347
FBXO9
F-box protein 9
chr3_+_85858321 0.453 NM_153184
CADM2
cell adhesion molecule 2
chr19_+_61624 0.450 NM_001005240
OR4F4
OR4F17
olfactory receptor, family 4, subfamily F, member 4
olfactory receptor, family 4, subfamily F, member 17
chrX_+_123062143 0.449 STAG2
stromal antigen 2
chr13_+_27264779 0.444 NM_145657
GSX1
GS homeobox 1
chr5_+_57823017 0.440 NM_152687
GAPT
GRB2-binding adaptor protein, transmembrane
chr11_-_57947358 0.437 NM_001005566
OR5B2
olfactory receptor, family 5, subfamily B, member 2
chr7_+_94135384 0.436 PEG10
paternally expressed 10
chrX_-_123925343 0.435 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1(Drosophila)


chr15_-_58706934 0.435 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chrX_-_111809929 0.434 NM_178175
LHFPL1
lipoma HMGIC fusion partner-like 1
chr10_-_50012058 0.433 NM_001164484
FAM170B
family with sequence similarity 170, member B
chr2_+_218641982 0.431 NM_198483
RUFY4
RUN and FYVE domain containing 4
chr4_+_73123712 0.431 NM_001144756
NM_053036
NPFFR2

neuropeptide FF receptor 2

chr15_+_60726801 0.430 NM_015059
TLN2
talin 2
chr11_+_6762823 0.430 NM_001004489
OR2AG1
olfactory receptor, family 2, subfamily AG, member 1
chr4_+_70950747 0.428 NM_002159
HTN1
histatin 1
chr21_-_26345294 0.427


chr2_+_95621492 0.425 NM_138800
TRIM43
tripartite motif containing 43
chr2_-_179380301 0.424 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr18_-_26996742 0.424 NM_004948
NM_024421
DSC1

desmocollin 1

chr7_+_156677777 0.420


chr12_-_10846435 0.419 NM_023919
TAS2R7
taste receptor, type 2, member 7
chr15_+_49988882 0.417 TMOD3
tropomodulin 3 (ubiquitous)
chr4_-_70115037 0.417 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr11_+_55297489 0.416 NM_001001967
OR5D13
olfactory receptor, family 5, subfamily D, member 13
chr1_-_144779601 0.412 NM_001101663
NBPF11
NBPF24
neuroblastoma breakpoint family, member 11
neuroblastoma breakpoint family, member 24
chrX_+_107174855 0.409 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr8_-_53484753 0.408 NM_014682
ST18
suppression of tumorigenicity 18 (breast carcinoma) (zinc finger protein)
chr14_-_20179689 0.408 NM_001001968
OR6S1
olfactory receptor, family 6, subfamily S, member 1
chrX_-_100759562 0.407 NM_001009584
NM_001184768
NM_019007
ARMCX6


armadillo repeat containing, X-linked 6


chr14_-_73095396 0.406 NM_203309
HEATR4
HEAT repeat containing 4
chr11_-_55128424 0.405 NM_001004700
OR4C11
olfactory receptor, family 4, subfamily C, member 11
chr3_+_144165470 0.396 U2SURP
U2 snRNP-associated SURP domain containing
chr1_+_117098579 0.396 NM_001767
CD2
CD2 molecule
chr4_+_154083584 0.396 NM_033393
FHDC1
FH2 domain containing 1
chr1_+_195055483 0.394 NM_002113
CFHR1
complement factor H-related 1
chr3_+_12367993 0.392 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr20_+_186376 0.390 NM_207469
DEFB132
defensin, beta 132
chr1_-_115060857 0.388 NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr6_+_100161370 0.388 NM_021620
PRDM13
PR domain containing 13
chr4_-_170314382 0.386 SH3RF1
SH3 domain containing ring finger 1
chr2_+_159533329 0.386 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr11_+_113280727 0.383 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chrX_-_142632181 0.380 NM_001009615
SPANXN2
SPANX family, member N2
chr11_+_5862076 0.377 NM_001005165
OR52E4
olfactory receptor, family 52, subfamily E, member 4
chr1_+_103999663 0.376 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr21_-_14501114 0.375 NM_198996
LIPI
lipase, member I
chr9_-_106407728 0.374 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr16_-_70591377 0.373 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr2_-_47969350 0.372 NM_025133
FBXO11
F-box protein 11
chr7_+_128795280 0.368 AHCYL2
adenosylhomocysteinase-like 2
chr1_-_32054164 0.368 NM_144569
SPOCD1
SPOC domain containing 1
chr12_-_4358968 0.368 NM_020638
FGF23
fibroblast growth factor 23
chr7_+_93373755 0.365 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chrX_+_9895397 0.363 NM_001195081
LOC100288814
hypothetical protein LOC100288814
chr6_-_50124322 0.362 NM_001037498
DEFB112
defensin, beta 112
chr3_+_110024234 0.362 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr12_+_99274987 0.361 NM_001145288
NM_139319
SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr11_-_6005546 0.360 NM_001001917
OR56A1
olfactory receptor, family 56, subfamily A, member 1
chrX_+_99726445 0.360 NM_022144
TNMD
tenomodulin
chrX_+_140810117 0.359 NM_177456
MAGEC3
melanoma antigen family C, 3
chrX_+_16051344 0.358 NM_005314
GRPR
gastrin-releasing peptide receptor
chr21_+_30929425 0.358 NM_181616
KRTAP20-2
keratin associated protein 20-2
chrX_+_41433169 0.357 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chrX_-_77801480 0.356 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr12_+_53901075 0.356 NM_001005280
OR10A7
olfactory receptor, family 10, subfamily A, member 7
chr5_+_140166842 0.355 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr1_+_143807876 0.355 SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr6_+_4781330 0.355 NM_001143970
CDYL
chromodomain protein, Y-like
chr15_-_63108974 0.355 NM_139242
MTFMT
mitochondrial methionyl-tRNA formyltransferase
chr5_+_140723939 0.353 NM_018918
NM_032054
PCDHGA5

protocadherin gamma subfamily A, 5

chr9_-_28709302 0.351 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_+_146250978 0.350 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.01 7.10e-26 GO:0007608 sensory perception of smell
3.80 1.08e-25 GO:0007606 sensory perception of chemical stimulus
2.67 1.53e-18 GO:0007600 sensory perception
2.08 3.59e-14 GO:0050877 neurological system process
1.90 1.16e-12 GO:0003008 system process
1.29 3.08e-05 GO:0032501 multicellular organismal process
1.20 2.02e-02 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.49 6.50e-13 GO:0005886 plasma membrane
1.48 8.57e-13 GO:0071944 cell periphery
1.22 1.55e-04 GO:0044425 membrane part
1.23 8.88e-04 GO:0031224 intrinsic to membrane
1.23 1.01e-03 GO:0016021 integral to membrane
1.17 1.71e-03 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
4.20 5.30e-28 GO:0004984 olfactory receptor activity
2.93 8.35e-26 GO:0004930 G-protein coupled receptor activity
2.21 1.72e-17 GO:0004888 transmembrane receptor activity
1.99 1.48e-16 GO:0004872 receptor activity
1.75 2.71e-12 GO:0004871 signal transducer activity
1.75 2.71e-12 GO:0060089 molecular transducer activity