Motif ID: TEAD1.p2

Z-value: 1.077


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TEAD3chr6_-_355726940.495.3e-02Click!
TEAD2chr19_-_545574500.391.4e-01Click!
TEAD1chr11_+_12652427-0.381.5e-01Click!
TEAD4chr12_+_29392500.234.0e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_12983959 1.596 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr1_-_12599934 1.430 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr1_+_18680010 1.299 NM_152375
KLHDC7A
kelch domain containing 7A
chr12_-_120725210 1.173 LOC338799
hypothetical LOC338799
chr11_-_2907169 1.066 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr3_-_135575925 1.052 NM_016201
AMOTL2
angiomotin like 2
chr9_+_94776538 1.037 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr19_-_51979838 1.016 NM_001145145
SLC1A5
solute carrier family 1 (neutral amino acid transporter), member 5
chr15_+_63156206 1.008 NM_001101362
KBTBD13
kelch repeat and BTB (POZ) domain containing 13
chr16_-_3131348 1.003


chr17_+_46267603 0.956 NM_175575
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr10_+_6284845 0.950 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr11_+_74548472 0.926 NM_001145211
SLCO2B1
solute carrier organic anion transporter family, member 2B1
chr11_+_1812115 0.914 NM_138567
SYT8
synaptotagmin VIII
chr3_-_46879883 0.909 NM_000258
MYL3
myosin, light chain 3, alkali; ventricular, skeletal, slow
chr17_+_24095135 0.886 NM_004295
TRAF4
TNF receptor-associated factor 4
chr3_-_150533948 0.880 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_-_1283770 0.871 NM_032348
MXRA8
matrix-remodelling associated 8
chr6_-_132314004 0.859 NM_001901
CTGF
connective tissue growth factor
chr7_+_72883128 0.858 NM_001305
CLDN4
claudin 4
chr1_+_16131633 0.843


chr19_+_39664706 0.840 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr2_+_113546365 0.826 NM_032556
IL1F10
interleukin 1 family, member 10 (theta)
chr17_-_76720342 0.825 AATK
apoptosis-associated tyrosine kinase
chr6_-_31007905 0.824 NM_205854
SFTA2
surfactant associated 2
chr19_+_16115454 0.823 HSH2D
hematopoietic SH2 domain containing
chr19_-_60272708 0.817 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr15_-_39973566 0.804 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr10_-_61819493 0.803 NM_020987
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr4_+_8322358 0.770 NM_053044
HTRA3
HtrA serine peptidase 3
chrX_-_10548458 0.766 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr17_-_36347197 0.765 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr1_-_43509187 0.761 EBNA1BP2
EBNA1 binding protein 2
chr11_-_2127368 0.759 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr11_-_46896484 0.719 NM_002334
LRP4
low density lipoprotein receptor-related protein 4
chr16_+_22432344 0.715 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr17_-_53961709 0.712 NM_004574
SEPT4
septin 4
chr10_+_104145421 0.710 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr9_+_131123115 0.704 NM_001012715
C9orf106
chromosome 9 open reading frame 106
chr11_-_76058542 0.688 NM_005512
LRRC32
leucine rich repeat containing 32
chr1_-_199613427 0.683 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr22_+_22907443 0.680 NM_019601
SUSD2
sushi domain containing 2
chr15_+_94670160 0.680 NM_001145155
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr22_+_22907417 0.674 SUSD2
sushi domain containing 2
chr9_+_117955890 0.672 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr19_-_4468715 0.666 NM_001080400
PLIN4
perilipin 4
chr1_-_24311212 0.656 NM_152372
MYOM3
myomesin family, member 3
chr20_-_23915431 0.645 NM_178312
GGTLC1
gamma-glutamyltransferase light chain 1
chr1_+_24522116 0.642 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr19_-_10152056 0.637


chr12_-_12310969 0.636 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr1_+_26358097 0.623 NM_024869
GRRP1
glycine/arginine rich protein 1
chr7_-_100667750 0.622 NM_014343
CLDN15
claudin 15
chr19_-_13478037 0.619 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr3_-_10522340 0.615 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr1_-_199613406 0.611 TNNT2
troponin T type 2 (cardiac)
chr6_-_168222645 0.610 NM_024919
FRMD1
FERM domain containing 1
chr10_+_73703682 0.602 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr22_-_20419975 0.601 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr17_-_44154878 0.600 NM_032391
PRAC
prostate cancer susceptibility candidate
chr3_-_10522267 0.585 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr12_-_55920741 0.584 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr17_-_37828643 0.583 NM_012232
PTRF
polymerase I and transcript release factor
chr16_-_62573 0.576 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr16_+_68765428 0.555 NM_173619
CLEC18C
CLEC18A
CLEC18B
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
C-type lectin domain family 18, member B
chr8_-_37847095 0.553 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr1_-_25164061 0.550 NM_001031680
RUNX3
runt-related transcription factor 3
chr3_-_10522221 0.545 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr6_+_167445284 0.538 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr1_-_16355013 0.534 NM_004431
EPHA2
EPH receptor A2
chr16_+_2461500 0.533 NM_006181
NTN3
netrin 3
chr16_+_1246273 0.530 NM_012217
TPSD1
tryptase delta 1
chr16_+_29730909 0.526 NM_145239
PRRT2
proline-rich transmembrane protein 2
chr16_+_86542449 0.526 NM_001173539
NM_001173540
NM_001173541
NM_017869
NM_079837
BANP




BTG3 associated nuclear protein




chr7_+_989472 0.517 CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr22_+_40286957 0.511 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr18_+_70352779 0.510 CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr16_+_29731058 0.509 PRRT2
proline-rich transmembrane protein 2
chr17_-_15495534 0.498 TRIM16
tripartite motif containing 16
chrX_+_70232362 0.483 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr12_+_52697160 0.480 HOXC5
HOXC6
homeobox C5
homeobox C6
chr21_+_43024936 0.478 PDE9A
phosphodiesterase 9A
chr17_-_53961533 0.478 SEPT4
septin 4
chr2_-_42844705 0.471 NM_148962
OXER1
oxoeicosanoid (OXE) receptor 1
chr16_+_28797309 0.470 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr12_+_52696908 0.470 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr7_-_155297576 0.468 NM_000193
SHH
sonic hedgehog
chr17_-_15463742 0.462 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr11_-_85107569 0.461 NM_206929
SYTL2
synaptotagmin-like 2
chr13_+_90848875 0.460 NM_004466
GPC5
glypican 5
chr6_+_31651319 0.458 NM_000594
TNF
tumor necrosis factor
chr19_+_55627971 0.455 NM_004533
MYBPC2
myosin binding protein C, fast type
chr1_-_201411533 0.450 NM_004997
MYBPH
myosin binding protein H
chrX_-_13307425 0.449


chr1_-_154941861 0.445 NM_001878
CRABP2
cellular retinoic acid binding protein 2
chr3_+_38322430 0.442 NM_004803
SLC22A14
solute carrier family 22, member 14
chr1_+_228949752 0.442 NM_006615
NM_016452
CAPN9

calpain 9

chr1_-_3437834 0.437 MEGF6
multiple EGF-like-domains 6
chr5_+_118719448 0.435 NM_014350
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr2_+_218833982 0.433 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr1_+_114323552 0.425 NM_020190
OLFML3
olfactomedin-like 3
chr10_-_125843092 0.424 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr9_+_90339835 0.422 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr22_+_21318779 0.420 NM_199127
GGTLC2
gamma-glutamyltransferase light chain 2
chr7_+_989321 0.419 NM_017781
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr10_-_70846573 0.417 NM_001057
TACR2
tachykinin receptor 2
chr2_+_237143118 0.413 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr1_-_6218621 0.412 NM_012405
ICMT
isoprenylcysteine carboxyl methyltransferase
chr6_+_158653679 0.405 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr6_+_155453114 0.402 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr7_+_111850367 0.400 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr1_-_201583989 0.398 FMOD
fibromodulin
chr7_+_99865340 0.397 MEPCE
methylphosphate capping enzyme
chr19_+_7891884 0.395 SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr12_+_47498778 0.395 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr8_-_103735194 0.394 NM_001032282
KLF10
Kruppel-like factor 10
chr1_-_11841476 0.387 NM_002521
NPPB
natriuretic peptide B
chr9_-_129573330 0.387 NM_005489
SH2D3C
SH2 domain containing 3C
chr6_+_41712907 0.387 MDFI
MyoD family inhibitor
chr11_+_186760 0.387 NM_053280
ODF3
outer dense fiber of sperm tails 3
chr1_-_158098962 0.384 NM_001013661
VSIG8
V-set and immunoglobulin domain containing 8
chr5_-_37871685 0.381 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr1_-_199704773 0.376 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr6_+_31910623 0.372 NM_001040437
NM_001040438
C6orf48

chromosome 6 open reading frame 48

chr4_-_57242492 0.369 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr8_+_145158432 0.366 NM_001134374
NM_198572
SPATC1

spermatogenesis and centriole associated 1

chr3_-_52844274 0.366 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr1_-_36721501 0.365 NM_000760
NM_156039
NM_172313
CSF3R


colony stimulating factor 3 receptor (granulocyte)


chrX_+_47305459 0.364 NM_001654
ARAF
v-raf murine sarcoma 3611 viral oncogene homolog
chr17_+_4841923 0.364 NM_006612
KIF1C
kinesin family member 1C
chr12_-_94708641 0.362 NM_021229
NTN4
netrin 4
chr1_+_26389638 0.361 NM_198137
CATSPER4
cation channel, sperm associated 4
chr18_-_72857665 0.360 MBP
myelin basic protein
chr5_-_37871349 0.357 NM_199231
GDNF
glial cell derived neurotrophic factor
chr18_+_13815542 0.357 NM_005913
MC5R
melanocortin 5 receptor
chr5_+_118719591 0.355 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_+_176494690 0.355 NSD1
nuclear receptor binding SET domain protein 1
chr7_+_149699185 0.353 NM_014374
REPIN1
replication initiator 1
chr17_+_7699100 0.352 NM_203411
TMEM88
transmembrane protein 88
chr12_-_121404968 0.352 CLIP1
CAP-GLY domain containing linker protein 1
chr7_-_107558021 0.348 NM_007356
LAMB4
laminin, beta 4
chr5_-_150118747 0.346 NM_001135643
NM_016221
DCTN4

dynactin 4 (p62)

chr8_-_38505331 0.346 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr1_+_26973804 0.344 ARID1A
AT rich interactive domain 1A (SWI-like)
chr2_-_238164452 0.343 NM_022449
RAB17
RAB17, member RAS oncogene family
chr2_-_238164042 0.342 RAB17
RAB17, member RAS oncogene family
chr8_-_108579270 0.341 NM_001146
ANGPT1
angiopoietin 1
chr1_-_17179694 0.340 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr1_-_152201814 0.338 SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr17_+_25292748 0.335 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr16_+_68542126 0.335 NM_001136214
CLEC18A
C-type lectin domain family 18, member A
chr21_+_37496616 0.334 TTC3
tetratricopeptide repeat domain 3
chrX_+_53128207 0.332 NM_022117
TSPYL2
TSPY-like 2
chr3_+_9919511 0.332 NM_001193380
NM_153480
IL17RE

interleukin 17 receptor E

chr8_-_142446546 0.331 NM_005293
GPR20
G protein-coupled receptor 20
chr7_-_158073121 0.331 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr18_+_70352649 0.331 NM_032649
CNDP1
carnosine dipeptidase 1 (metallopeptidase M20 family)
chr16_+_1230678 0.330 NM_003294
TPSB2
TPSAB1
tryptase beta 2 (gene/pseudogene)
tryptase alpha/beta 1
chr11_-_124311512 0.329 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr19_-_44497815 0.328 NM_020862
LRFN1
leucine rich repeat and fibronectin type III domain containing 1
chr11_+_46651090 0.328 ATG13
ATG13 autophagy related 13 homolog (S. cerevisiae)
chr18_-_19496590 0.326 NM_173505
ANKRD29
ankyrin repeat domain 29
chr19_-_17047228 0.326 NM_001011699
NM_033417
HAUS8

HAUS augmin-like complex, subunit 8

chr9_+_130485754 0.325 NM_001122821
SET
SET nuclear oncogene
chr22_+_20316968 0.324 NM_152612
CCDC116
coiled-coil domain containing 116
chr11_-_6600385 0.323 DCHS1
dachsous 1 (Drosophila)
chr10_-_11614279 0.323 NM_001080491
USP6NL
USP6 N-terminal like
chr6_+_43565192 0.323 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr7_+_99865189 0.321 NM_019606
MEPCE
methylphosphate capping enzyme
chr8_-_37576515 0.315 LOC157860
hypothetical protein LOC157860
chr5_-_39460687 0.313 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr1_-_38003391 0.313 NM_001099439
NM_173641
EPHA10

EPH receptor A10

chr1_-_149698516 0.312 NM_001194937
NM_001194938
NM_015100
NM_145796
POGZ



pogo transposable element with ZNF domain



chr22_-_24088523 0.311 NM_182492
LRP5L
low density lipoprotein receptor-related protein 5-like
chr3_-_49916304 0.305 NM_002447
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr11_-_47330797 0.305 NM_000256
MYBPC3
myosin binding protein C, cardiac
chr17_+_19999784 0.301 NM_001033554
NM_001033555
SPECC1

sperm antigen with calponin homology and coiled-coil domains 1

chr9_+_99303282 0.301 NM_001166116
TMOD1
tropomodulin 1
chr10_+_50177192 0.299 NM_001135196
NM_199459
C10orf71

chromosome 10 open reading frame 71

chr9_-_132759045 0.296 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr8_-_42184350 0.295 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr11_+_7574992 0.293 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_212791597 0.293 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_62278109 0.293 NM_024784
ZBTB3
zinc finger and BTB domain containing 3
chr17_-_44663107 0.291 NM_001143804
NM_178500
PHOSPHO1

phosphatase, orphan 1

chr19_+_53951155 0.290 NM_019113
FGF21
fibroblast growth factor 21
chr6_-_31789824 0.290


chr15_-_41904059 0.289 NM_005926
MFAP1
microfibrillar-associated protein 1
chr11_-_116213511 0.288 NM_000039
APOA1
apolipoprotein A-I
chr3_-_113841967 0.288 CCDC80
coiled-coil domain containing 80
chr7_+_100302885 0.287 NM_003302
TRIP6
thyroid hormone receptor interactor 6
chr7_+_39739690 0.286 NCRNA00265
non-protein coding RNA 265
chr11_-_85108030 0.285 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr9_+_99303639 0.285 NM_003275
TMOD1
tropomodulin 1
chr12_+_102859354 0.285 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr15_+_72687765 0.284 NM_003992
CLK3
CDC-like kinase 3
chr4_-_89963177 0.281 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr8_-_42184194 0.280 PLAT
plasminogen activator, tissue
chr3_-_50333859 0.278 HYAL2
hyaluronoglucosaminidase 2
chr19_+_17239148 0.275 NM_001033549
NM_014173
BABAM1

BRISC and BRCA1 A complex member 1


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
4.86 1.32e-03 GO:0030048 actin filament-based movement
2.42 1.34e-03 GO:0030029 actin filament-based process
6.44 3.78e-02 GO:0006942 regulation of striated muscle contraction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.50 1.10e-05 GO:0005576 extracellular region
2.16 4.08e-04 GO:0031012 extracellular matrix
2.21 1.28e-03 GO:0005578 proteinaceous extracellular matrix
1.61 1.44e-03 GO:0044421 extracellular region part
3.13 1.58e-03 GO:0044420 extracellular matrix part
3.60 1.63e-02 GO:0016459 myosin complex
2.04 2.58e-02 GO:0015629 actin cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
14.16 2.52e-02 GO:0032036 myosin heavy chain binding