Motif ID: ZNF423.p2

Z-value: 3.307


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF423chr16_-_484184180.524.0e-02Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_1992862 3.891 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr1_+_1104939 3.713 NM_153254
TTLL10
tubulin tyrosine ligase-like family, member 10
chr19_-_1997229 3.679 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr16_-_3131348 3.677


chr19_-_1993022 3.610 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr16_+_2954217 3.443 NM_024507
NM_172229
KREMEN2

kringle containing transmembrane protein 2

chr11_-_44928803 3.440 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr17_-_975809 3.428 ABR
active BCR-related gene
chr11_+_76561471 3.381 MYO7A
myosin VIIA
chr22_+_20067662 3.308 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr19_-_1989937 3.303 MKNK2
MAP kinase interacting serine/threonine kinase 2
chrX_+_152608159 3.297 NM_001142806
SLC6A8
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr1_-_226202210 3.292 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr19_+_54872220 3.090 PRMT1
protein arginine methyltransferase 1
chr1_-_226530350 3.072


chr2_+_218833982 3.052 NM_001077191
NM_001077194
NM_170699
GPBAR1


G protein-coupled bile acid receptor 1


chr4_+_1764802 3.025 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr12_+_131577229 3.012 NM_001142641
FBRSL1
fibrosin-like 1
chr17_-_35017650 3.006 NEUROD2
neurogenic differentiation 2
chr14_+_99273751 2.980 EML1
echinoderm microtubule associated protein like 1
chr17_-_35017691 2.980 NM_006160
NEUROD2
neurogenic differentiation 2
chrX_-_48713194 2.855 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_+_54872304 2.802 NM_001536
NM_198318
PRMT1

protein arginine methyltransferase 1

chr21_-_45786709 2.664 NM_194255
SLC19A1
solute carrier family 19 (folate transporter), member 1
chr22_+_28446288 2.641 NM_182527
CABP7
calcium binding protein 7
chr9_+_138997265 2.592 NM_207510
LCNL1
lipocalin-like 1
chr21_+_45699830 2.582 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr12_+_109956210 2.575 NM_015267
CUX2
cut-like homeobox 2
chr11_-_1026654 2.538 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr1_+_226261374 2.526 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr6_+_33352886 2.522 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr19_+_50663089 2.512 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr9_-_132804243 2.490 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr2_-_144991556 2.470 ZEB2
zinc finger E-box binding homeobox 2
chr6_+_43846372 2.431 VEGFA
vascular endothelial growth factor A
chr19_+_4423149 2.419 NM_001001520
NM_032631
HDGFRP2

hepatoma-derived growth factor-related protein 2

chrX_+_153339814 2.418 NM_017514
PLXNA3
plexin A3
chr3_+_13496714 2.410 NM_024827
NM_001136041
HDAC11

histone deacetylase 11

chr11_+_1925162 2.401 MRPL23
mitochondrial ribosomal protein L23
chr9_-_139068269 2.379 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr9_+_135880363 2.374 NCRNA00094
non-protein coding RNA 94
chr11_-_67028415 2.353 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr6_+_43846155 2.348 VEGFA
vascular endothelial growth factor A
chr19_+_40716153 2.346 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_+_1925075 2.301 NM_021134
MRPL23
mitochondrial ribosomal protein L23
chr19_-_55524445 2.299 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_4983899 2.294


chr6_+_41712907 2.264 MDFI
MyoD family inhibitor
chr11_+_60448487 2.262 NM_017870
NM_178031
TMEM132A

transmembrane protein 132A

chrX_-_135941498 2.253 NM_054021
GPR101
G protein-coupled receptor 101
chr19_+_54996613 2.234


chr1_+_110056386 2.234 NM_000851
GSTM5
glutathione S-transferase mu 5
chr17_+_45993338 2.229 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr11_-_68537243 2.225 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chr5_-_525916 2.224 LOC25845
hypothetical LOC25845
chr11_+_17714070 2.180 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_+_8633116 2.164 NM_080819
GPR78
G protein-coupled receptor 78
chr10_-_134940315 2.151 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr7_+_99919485 2.141 NM_173564
C7orf51
chromosome 7 open reading frame 51
chr20_+_61654816 2.130 NM_024059
C20orf195
chromosome 20 open reading frame 195
chrX_+_152699616 2.127 NM_001170760
NM_001170761
NM_014370
SRPK3


SRSF protein kinase 3


chr10_+_135190855 2.116 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr5_+_170668892 2.083 NM_021025
TLX3
T-cell leukemia homeobox 3
chr2_+_121271336 2.082 NM_005270
GLI2
GLI family zinc finger 2
chr4_-_154929657 2.073 NM_003013
SFRP2
secreted frizzled-related protein 2
chr6_+_41622111 2.056 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr14_-_104706159 2.052 NM_002226
NM_145159
JAG2

jagged 2

chr22_-_36153449 2.031 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr5_-_1498510 2.012 NM_001044
SLC6A3
solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr19_+_1358664 1.997 DAZAP1
DAZ associated protein 1
chr11_+_1848674 1.993 NM_001013254
NM_001013255
LSP1

lymphocyte-specific protein 1

chr1_-_2333800 1.967 PEX10
peroxisomal biogenesis factor 10
chr3_+_13585239 1.961 NM_001165035
FBLN2
fibulin 2
chr6_+_43845915 1.944 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_003376
VEGFA















vascular endothelial growth factor A















chr17_+_73676219 1.933 NM_004710
SYNGR2
synaptogyrin 2
chr11_-_2400817 1.899 NM_014555
TRPM5
transient receptor potential cation channel, subfamily M, member 5
chr21_+_44377974 1.883 C21orf33
chromosome 21 open reading frame 33
chr10_+_3099708 1.883 NM_002627
PFKP
phosphofructokinase, platelet
chr21_+_44544381 1.877 PFKL
phosphofructokinase, liver
chr5_+_175241449 1.869 CPLX2
complexin 2
chr22_+_48740432 1.864 PIM3
pim-3 oncogene
chr16_+_2461500 1.862 NM_006181
NTN3
netrin 3
chr1_-_2333863 1.847 NM_002617
NM_153818
PEX10

peroxisomal biogenesis factor 10

chr21_+_44544392 1.843 PFKL
phosphofructokinase, liver
chr8_-_145085616 1.824 NM_201384
PLEC
plectin
chr7_+_75977680 1.817 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr15_+_62230962 1.803 NM_024798
SNX22
sorting nexin 22
chr17_-_76827370 1.784 C17orf56
chromosome 17 open reading frame 56
chr9_+_134027154 1.776 NM_032536
NTNG2
netrin G2
chr16_+_639278 1.746 NM_145294
WDR90
WD repeat domain 90
chr9_-_138378061 1.742 NM_001080849
DNLZ
DNL-type zinc finger
chr9_+_100609754 1.719 NM_024642
GALNT12
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12 (GalNAc-T12)
chr19_+_59333232 1.714 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr1_+_945399 1.711


chr10_+_99069007 1.710 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr11_-_62539857 1.686 NM_001184732
NM_001184733
NM_001184736
NM_004254
SLC22A8



solute carrier family 22 (organic anion transporter), member 8



chr11_-_6451561 1.681 NM_006458
NM_033278
TRIM3

tripartite motif containing 3

chr2_+_232281491 1.674 PTMA
prothymosin, alpha
chr21_+_44544349 1.672 NM_002626
PFKL
phosphofructokinase, liver
chr9_+_139892049 1.648 NM_000718
CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chr19_+_52214885 1.631 NPAS1
neuronal PAS domain protein 1
chr19_-_54005916 1.631 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chrX_-_19050499 1.605 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr16_+_2138688 1.587 RAB26
RAB26, member RAS oncogene family
chr19_+_19510056 1.587 NM_153221
CILP2
cartilage intermediate layer protein 2
chr22_-_49062461 1.585 PLXNB2
plexin B2
chr19_+_18391423 1.571


chr19_+_41051186 1.569 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr20_-_25010756 1.562 NM_014588
NM_199425
VSX1

visual system homeobox 1

chr16_+_170334 1.558 NM_005331
HBQ1
hemoglobin, theta 1
chr19_-_1763198 1.551 NM_001178002
NM_138813
ATP8B3

ATPase, aminophospholipid transporter, class I, type 8B, member 3

chr8_-_22022757 1.549 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr6_+_43846735 1.547 VEGFA
vascular endothelial growth factor A
chr19_+_13111072 1.547 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr16_+_2025922 1.541 SLC9A3R2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr1_+_55277795 1.536 PCSK9
proprotein convertase subtilisin/kexin type 9
chr19_+_19510098 1.523 CILP2
cartilage intermediate layer protein 2
chrX_+_30175191 1.518 NM_177404
MAGEB1
melanoma antigen family B, 1
chr2_-_233060774 1.517 NM_004826
ECEL1
endothelin converting enzyme-like 1
chr7_+_75928907 1.515 NM_001102594
NM_001102595
NM_020892
DTX2


deltex homolog 2 (Drosophila)


chr12_+_131797455 1.493 NM_001170543
NM_001170544
NM_138575
PGAM5


phosphoglycerate mutase family member 5


chr20_+_60558369 1.492 C20orf166
chromosome 20 open reading frame 166
chr1_+_16247870 1.491 NM_001165945
CLCNKB
chloride channel Kb
chr7_-_100009205 1.485 NM_001168682
SAP25
sin3A-binding protein 25
chr19_-_18409971 1.480 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chrX_+_70899864 1.469 NM_001145140
NM_001145139
CXorf49
CXorf49B
chromosome X open reading frame 49
chromosome X open reading frame 49B
chr20_-_30636535 1.468 LOC284804
hypothetical protein LOC284804
chr19_+_47509274 1.468 NM_173633
TMEM145
transmembrane protein 145
chr19_-_1083109 1.449 NM_001100122
SBNO2
strawberry notch homolog 2 (Drosophila)
chr16_-_1086244 1.448 NM_207419
C1QTNF8
C1q and tumor necrosis factor related protein 8
chr11_+_65792603 1.437 NM_030981
RAB1B
RAB1B, member RAS oncogene family
chr14_+_103065226 1.424 NM_152307
TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr19_+_1158129 1.423 EFNA2
ephrin-A2
chr11_+_64631919 1.421 C11orf2
chromosome 11 open reading frame 2
chr10_+_134823925 1.419 NM_152643
KNDC1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr20_+_61838479 1.407 LIME1
Lck interacting transmembrane adaptor 1
chrX_+_69581429 1.406 NM_021120
DLG3
discs, large homolog 3 (Drosophila)
chr11_-_67153959 1.398 NM_181843
NUDT8
nudix (nucleoside diphosphate linked moiety X)-type motif 8
chr7_-_1562272 1.382 NM_001097620
TMEM184A
transmembrane protein 184A
chr22_-_19418954 1.373 NM_002650
PI4KA
phosphatidylinositol 4-kinase, catalytic, alpha
chr13_+_113587674 1.371 GAS6
growth arrest-specific 6
chr17_+_73738985 1.371 NM_001145529
TMEM235
transmembrane protein 235
chr1_-_6448737 1.368 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr18_+_75261231 1.365 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr19_+_1358750 1.349 DAZAP1
DAZ associated protein 1
chr1_-_6243621 1.345 NM_207370
GPR153
G protein-coupled receptor 153
chr1_+_1256585 1.343 NM_152228
TAS1R3
taste receptor, type 1, member 3
chr9_-_138234707 1.342 NM_014564
LHX3
LIM homeobox 3
chr1_+_31855873 1.340 NM_001525
HCRTR1
hypocretin (orexin) receptor 1
chr14_+_103065288 1.340 TRMT61A
tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr2_+_232281470 1.339 NM_001099285
NM_002823
PTMA

prothymosin, alpha

chr19_-_56303434 1.338 NM_145232
CTU1
cytosolic thiouridylase subunit 1 homolog (S. pombe)
chr6_+_43845875 1.331 VEGFA
vascular endothelial growth factor A
chr15_-_75711743 1.321 NM_032808
LINGO1
leucine rich repeat and Ig domain containing 1
chr2_-_144991386 1.311 ZEB2
zinc finger E-box binding homeobox 2
chr16_+_2071631 1.309 TSC2
tuberous sclerosis 2
chr3_-_129690056 1.309 NM_001145661
GATA2
GATA binding protein 2
chr19_-_43406621 1.307 NM_001135155
NM_004647
DPF1

D4, zinc and double PHD fingers family 1

chr16_-_72959492 1.283 LOC283922
pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr12_+_108636569 1.269 NM_032829
C12orf34
chromosome 12 open reading frame 34
chr1_+_1437358 1.269 NM_001170535
NM_018188
ATAD3A

ATPase family, AAA domain containing 3A

chr11_-_2248374 1.267 ASCL2
achaete-scute complex homolog 2 (Drosophila)
chr17_+_71065478 1.264 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr20_-_55275078 1.259 NM_001719
BMP7
bone morphogenetic protein 7
chr22_-_20235749 1.248 NM_001128633
RIMBP3C
RIMS binding protein 3C
chr11_+_834111 1.246 TSPAN4
tetraspanin 4
chr1_+_149521364 1.237 NM_020832
ZNF687
zinc finger protein 687
chr7_+_30140868 1.236 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr6_+_109868580 1.236 NM_003080
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr9_-_37894098 1.235 MCART1
mitochondrial carrier triple repeat 1
chr6_-_3172775 1.235 NM_178012
TUBB2B
tubulin, beta 2B
chr4_-_8124611 1.232 ABLIM2
actin binding LIM protein family, member 2
chr1_+_31823097 1.222 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr11_-_61415429 1.221 NM_021727
FADS3
fatty acid desaturase 3
chr14_+_103674812 1.220 NM_015656
KIF26A
kinesin family member 26A
chr19_-_15421761 1.220 NM_021241
WIZ
widely interspaced zinc finger motifs
chr1_+_11461764 1.219 NM_020780
PTCHD2
patched domain containing 2
chr3_-_58538110 1.217 FAM107A
family with sequence similarity 107, member A
chr20_+_61838389 1.213 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr19_+_8335010 1.198 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr17_+_41432452 1.197 NM_001007532
STH
saitohin
chr3_-_48569213 1.195 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr19_+_53589943 1.193 NM_000836
GRIN2D
glutamate receptor, ionotropic, N-methyl D-aspartate 2D
chr12_+_111829121 1.190 NM_001032409
NM_002534
NM_016816
OAS1


2',5'-oligoadenylate synthetase 1, 40/46kDa


chr2_-_120697441 1.179 TMEM185B
transmembrane protein 185B (pseudogene)
chr22_+_21852551 1.176 NM_004327
NM_021574
BCR

breakpoint cluster region

chr20_-_61600834 1.174 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr9_-_130526192 1.168 NM_032799
ZDHHC12
zinc finger, DHHC-type containing 12
chr2_-_120697382 1.164 TMEM185B
transmembrane protein 185B (pseudogene)
chr7_-_50828159 1.162 GRB10
growth factor receptor-bound protein 10
chr12_-_123568781 1.162


chr15_-_75711785 1.160 LINGO1
leucine rich repeat and Ig domain containing 1
chr20_-_61356247 1.158 NM_152864
NKAIN4
Na+/K+ transporting ATPase interacting 4
chr18_+_12244317 1.157 NM_001279
CIDEA
cell death-inducing DFFA-like effector a
chr7_+_6622051 1.153 NM_017560
ZNF853
zinc finger protein 853
chr16_+_69950116 1.150 NM_001740
NM_007088
CALB2

calbindin 2

chr7_-_27158726 1.146


chr21_+_44566063 1.142 PFKL
phosphofructokinase, liver
chr19_-_18409788 1.139 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr17_-_37144408 1.139 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1



Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 4.11e-04 GO:0051716 cellular response to stimulus
1.47 4.58e-04 GO:0007399 nervous system development
1.15 6.50e-04 GO:0065007 biological regulation
1.27 2.29e-03 GO:0007165 signal transduction
1.16 2.92e-03 GO:0050794 regulation of cellular process
1.25 4.08e-03 GO:0023052 signaling
1.15 4.64e-03 GO:0050789 regulation of biological process
1.29 7.75e-03 GO:0048731 system development
1.24 1.08e-02 GO:0032502 developmental process
1.25 1.17e-02 GO:0007275 multicellular organismal development
1.26 1.40e-02 GO:0048856 anatomical structure development
1.40 2.19e-02 GO:0009653 anatomical structure morphogenesis
1.52 2.75e-02 GO:0022008 neurogenesis
1.59 3.31e-02 GO:0030182 neuron differentiation
2.36 4.61e-02 GO:0045926 negative regulation of growth

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.35 2.61e-04 GO:0044459 plasma membrane part
1.21 4.12e-03 GO:0071944 cell periphery
1.21 5.23e-03 GO:0005886 plasma membrane
2.38 1.15e-02 GO:0031225 anchored to membrane
1.68 3.75e-02 GO:0045202 synapse
1.04 4.75e-02 GO:0044464 cell part
1.04 4.87e-02 GO:0005623 cell

Nothing significant found in function category.