Motif ID: NKX3-1.p2

Z-value: 2.138


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23596346-0.146.2e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_228064531 5.244 AGFG1
ArfGAP with FG repeats 1
chr9_+_21399132 4.351 NM_002170
 IFNA8
interferon, alpha 8
chr11_+_33319680 3.252 HIPK3
homeodomain interacting protein kinase 3
chr3_-_121117647 3.241 GSK3B
glycogen synthase kinase 3 beta
chr14_-_74669864 2.917 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr14_+_66901237 2.788 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_+_174598937 2.744 NM_014932
 NLGN1
neuroligin 1
chr2_+_114390975 2.707 ACTR3
ARP3 actin-related protein 3 homolog (yeast)
chr10_+_90336489 2.685 NM_001010939
 LIPJ
lipase, family member J
chr3_-_121445831 2.636 NM_001168271
NM_153002
 GPR156

G protein-coupled receptor 156

chr20_+_12937616 2.565 NM_018327
 SPTLC3
serine palmitoyltransferase, long chain base subunit 3
chr11_-_104332631 2.493 NM_033306
 CASP4
caspase 4, apoptosis-related cysteine peptidase
chr9_-_13240313 2.294 NM_003829
 MPDZ
multiple PDZ domain protein
chr3_-_99236520 2.281 NM_001105580
 GABRR3
gamma-aminobutyric acid (GABA) receptor, rho 3
chrX_+_114734074 2.262 NM_001136025
NM_001172335
 PLS3

plastin 3

chr4_+_119174947 2.131 NM_004784
 NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_64344307 2.102 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr14_-_24115268 2.048 NM_001911
 CTSG
cathepsin G
chr10_-_98280299 2.003 TM9SF3
transmembrane 9 superfamily member 3
chr6_+_153060722 1.999 NM_025107
 MYCT1
myc target 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
4.32 3.67e-31 GO:0007608 sensory perception of smell
4.11 1.89e-31 GO:0007606 sensory perception of chemical stimulus
2.75 2.04e-20 GO:0007600 sensory perception
1.99 6.50e-12 GO:0050877 neurological system process
1.82 1.53e-10 GO:0003008 system process
1.33 9.12e-07 GO:0032501 multicellular organismal process
1.26 2.06e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
1.41 2.12e-03 GO:0005576 extracellular region
1.40 1.60e-08 GO:0005886 plasma membrane
1.39 3.27e-08 GO:0071944 cell periphery
1.25 6.49e-06 GO:0044425 membrane part
1.25 2.05e-04 GO:0016021 integral to membrane
1.24 3.77e-04 GO:0031224 intrinsic to membrane
1.16 3.76e-03 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
13.61 3.32e-04 GO:0005132 interferon-alpha/beta receptor binding
8.38 1.60e-02 GO:0004522 pancreatic ribonuclease activity
4.48 8.78e-33 GO:0004984 olfactory receptor activity
3.30 1.04e-02 GO:0004867 serine-type endopeptidase inhibitor activity
2.77 2.52e-22 GO:0004930 G-protein coupled receptor activity
2.21 1.37e-17 GO:0004888 transmembrane receptor activity
1.97 4.22e-16 GO:0004872 receptor activity
1.75 1.96e-12 GO:0004871 signal transducer activity
1.75 1.96e-12 GO:0060089 molecular transducer activity