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Motif ID: NKX3-1.p2

Z-value: 2.138

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_228064531	5.244		AGFG1	ArfGAP with FG repeats 1
chr9_+_21399132	4.351	NM_002170	IFNA8	interferon, alpha 8
chr11_+_33319680	3.252		HIPK3	homeodomain interacting protein kinase 3
chr3_-_121117647	3.241		GSK3B	glycogen synthase kinase 3 beta
chr14_-_74669864	2.917		TMED10	transmembrane emp24-like trafficking protein 10 (yeast)
chr14_+_66901237	2.788		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_+_174598937	2.744	NM_014932	NLGN1	neuroligin 1
chr2_+_114390975	2.707		ACTR3	ARP3 actin-related protein 3 homolog (yeast)
chr10_+_90336489	2.685	NM_001010939	LIPJ	lipase, family member J
chr3_-_121445831	2.636	NM_001168271 NM_153002	GPR156	G protein-coupled receptor 156
chr20_+_12937616	2.565	NM_018327	SPTLC3	serine palmitoyltransferase, long chain base subunit 3
chr11_-_104332631	2.493	NM_033306	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr9_-_13240313	2.294	NM_003829	MPDZ	multiple PDZ domain protein
chr3_-_99236520	2.281	NM_001105580	GABRR3	gamma-aminobutyric acid (GABA) receptor, rho 3
chrX_+_114734074	2.262	NM_001136025 NM_001172335	PLS3	plastin 3
chr4_+_119174947	2.131	NM_004784	NDST3	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr6_+_64344307	2.102		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr14_-_24115268	2.048	NM_001911	CTSG	cathepsin G
chr10_-_98280299	2.003		TM9SF3	transmembrane 9 superfamily member 3
chr6_+_153060722	1.999	NM_025107	MYCT1	myc target 1
chr9_-_21218132	1.945	NM_021268	IFNA17	interferon, alpha 17
chr12_-_5925658	1.881	NM_020373	ANO2	anoctamin 2
chr3_-_115380539	1.851	NM_000796 NM_033663	DRD3	dopamine receptor D3
chr6_+_53043729	1.843	NM_012347	FBXO9	F-box protein 9
chr11_-_13474101	1.805	NM_000315	PTH	parathyroid hormone
chr4_+_152417774	1.788	NM_183375	PRSS48	protease, serine, 48
chr14_-_19553191	1.734	NM_001004712	OR4K14	olfactory receptor, family 4, subfamily K, member 14
chr2_+_37282516	1.723		LOC100505876	hypothetical LOC100505876
chr11_-_100505667	1.720	NM_000926	PGR	progesterone receptor
chr3_+_99350859	1.713	NM_001005514	OR5H14	olfactory receptor, family 5, subfamily H, member 14
chr7_+_94377145	1.702	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chrX_+_56772391	1.695		LOC550643	hypothetical LOC550643
chr9_-_25668855	1.658	NM_001004125	TUSC1	tumor suppressor candidate 1
chr20_+_9236446	1.651	NM_000933	PLCB4	phospholipase C, beta 4
chr1_-_246823691	1.623	NM_001004693	OR2T10	olfactory receptor, family 2, subfamily T, member 10
chrX_+_66705407	1.554	NM_001011645	AR	androgen receptor
chr7_+_80069439	1.538	NM_001001547	CD36	CD36 molecule (thrombospondin receptor)
chr17_+_58440629	1.522	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr13_+_51496679	1.504	NM_021645	ALG11 UTP14C	asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr20_-_1298493	1.487		FKBP1A	FK506 binding protein 1A, 12kDa
chr19_+_62844143	1.463		ZNF211	zinc finger protein 211
chr1_-_103269356	1.457		COL11A1	collagen, type XI, alpha 1
chrX_-_1291526	1.455	NM_001012288 NM_022148	CRLF2	cytokine receptor-like factor 2
chr10_+_90552466	1.452	NM_001128215	LIPM	lipase, family member M
chrX_+_115215985	1.450	NM_000686	AGTR2	angiotensin II receptor, type 2
chr12_+_8167494	1.449	NM_016184 NM_194447 NM_194448 NM_194450	CLEC4A	C-type lectin domain family 4, member A
chr9_-_21375258	1.440	NM_000605	IFNA2	interferon, alpha 2
chr11_-_7775064	1.435	NM_153444	OR5P2	olfactory receptor, family 5, subfamily P, member 2
chr2_+_207512522	1.409	NM_173077	CPO	carboxypeptidase O
chr7_-_123460722	1.403	NM_001136002	TMEM229A	transmembrane protein 229A
chr5_+_147238466	1.397	NM_054023	SCGB3A2	secretoglobin, family 3A, member 2
chr1_+_246578699	1.394	NM_001001918	OR14C36	olfactory receptor, family 14, subfamily C, member 36
chr14_+_44436176	1.389	NM_001017923	C14orf28	chromosome 14 open reading frame 28
chr10_+_118340460	1.386	NM_006229	PNLIPRP1	pancreatic lipase-related protein 1
chr3_+_50119261	1.385		RBM5	RNA binding motif protein 5
chr2_+_115538716	1.382	NM_001178037	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr2_-_233349469	1.365	NM_001172416 NM_001172417 NM_002242	KCNJ13	potassium inwardly-rectifying channel, subfamily J, member 13
chr11_+_89507465	1.362	NM_005467	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2
chr6_+_153113624	1.352	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr13_+_110637173	1.350	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chrX_-_32340291	1.337	NM_004011 NM_004012	DMD	dystrophin
chr5_-_58331515	1.332	NM_001197223	PDE4D	phosphodiesterase 4D, cAMP-specific
chr14_+_19655405	1.331	NM_001004715	OR4K17	olfactory receptor, family 4, subfamily K, member 17
chr10_+_116687904	1.321	NM_139169	TRUB1	TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr2_-_18634257	1.316	NM_001002006 NM_033253	NT5C1B-RDH14 NT5C1B	NT5C1B-RDH14 readthrough 5'-nucleotidase, cytosolic IB
chr5_-_160044844	1.295		ATP10B	ATPase, class V, type 10B
chr4_-_163304567	1.295	NM_001128427 NM_001128428 NM_020116	FSTL5	follistatin-like 5
chr10_-_126706442	1.278	NM_022802	CTBP2	C-terminal binding protein 2
chr12_+_79362256	1.264	NM_001145026	PTPRQ	protein tyrosine phosphatase, receptor type, Q
chr1_+_69998445	1.252	NM_020794	LRRC7	leucine rich repeat containing 7
chr21_-_26345294	1.251
chr15_+_92700167	1.250	NM_001159644	MCTP2	multiple C2 domains, transmembrane 2
chr14_-_106084085	1.225		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_29696662	1.224
chr3_-_174341653	1.202	NM_031955	SPATA16	spermatogenesis associated 16
chr14_-_105681377	1.197		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_+_55362802	1.192	NM_001005496	OR5D16	olfactory receptor, family 5, subfamily D, member 16
chr5_+_147423727	1.189	NM_001127698 NM_001127699 NM_006846	SPINK5	serine peptidase inhibitor, Kazal type 5
chr9_-_21177529	1.188	NM_021068	IFNA4	interferon, alpha 4
chr11_-_30910074	1.180	NM_020869	DCDC5	doublecortin domain containing 5
chr14_-_20098929	1.151	NM_001001673 NM_001110356 NM_001110357 NM_001110358 NM_001110359 NM_001110360 NM_001110361	RNASE9	ribonuclease, RNase A family, 9 (non-active)
chr9_+_4829763	1.147		RCL1	RNA terminal phosphate cyclase-like 1
chrX_+_89063595	1.142	NM_138960	TGIF2LX	TGFB-induced factor homeobox 2-like, X-linked
chr15_+_22781292	1.137		PAR5	Prader-Willi/Angelman syndrome-5
chr7_-_108311872	1.134	NM_001024607	C7orf66	chromosome 7 open reading frame 66
chr4_-_157006827	1.126	NM_017419	ACCN5	amiloride-sensitive cation channel 5, intestinal
chr1_+_74473672	1.126	NM_015978	TNNI3K	TNNI3 interacting kinase
chr14_+_74353417	1.123		YLPM1	YLP motif containing 1
chr9_-_41944687	1.113		MGC21881	hypothetical locus MGC21881
chr7_-_38915306	1.109	NM_014396 NM_080631	VPS41	vacuolar protein sorting 41 homolog (S. cerevisiae)
chr11_-_48330574	1.103	NM_001005513	OR4C45	olfactory receptor, family 4, subfamily C, member 45
chr9_-_21192201	1.095	NM_021057	IFNA7	interferon, alpha 7
chr16_+_82540172	1.083	NM_013370 NM_182980	OSGIN1	oxidative stress induced growth inhibitor 1
chr4_-_153523113	1.069	NM_001013415	FBXW7	F-box and WD repeat domain containing 7
chr3_+_99484421	1.069	NM_001005482	OR5H2	olfactory receptor, family 5, subfamily H, member 2
chr6_+_88021644	1.066		ZNF292	zinc finger protein 292
chr20_-_52120710	1.065	NM_003657	BCAS1	breast carcinoma amplified sequence 1
chr18_-_62422195	1.065	NM_021153	CDH19	cadherin 19, type 2
chr15_+_100163424	1.063	NM_001005326	OR4F6	olfactory receptor, family 4, subfamily F, member 6
chr3_+_99288706	1.058	NM_054106	OR5AC2	olfactory receptor, family 5, subfamily AC, member 2
chr2_+_203763649	1.046		RPL12	ribosomal protein L12
chr3_-_153541468	1.037	NM_001123228	TMEM14E	transmembrane protein 14E
chr9_+_95273241	1.028		FAM120A	family with sequence similarity 120A
chr16_-_70339666	1.012		AP1G1	adaptor-related protein complex 1, gamma 1 subunit
chr11_+_88550687	1.008	NM_000372	TYR	tyrosinase (oculocutaneous albinism IA)
chr2_+_211166323	1.004	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr11_-_57883117	1.004	NM_001005489	OR5B17	olfactory receptor, family 5, subfamily B, member 17
chr4_+_74520796	0.997	NM_001134	AFP	alpha-fetoprotein
chr22_-_39587944	0.993	NM_145174	DNAJB7	DnaJ (Hsp40) homolog, subfamily B, member 7
chr14_-_46882144	0.990	NM_182830	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2
chr5_+_140235114	0.985	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr15_+_64481270	0.979		MAP2K1	mitogen-activated protein kinase kinase 1
chr8_-_18710575	0.978	NM_206909	PSD3	pleckstrin and Sec7 domain containing 3
chr5_+_54491702	0.973	NM_001008397	GPX8	glutathione peroxidase 8 (putative)
chr1_-_246869181	0.939	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr6_-_52060327	0.931	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr14_+_88130482	0.927	NM_207662	ZC3H14	zinc finger CCCH-type containing 14
chr2_-_165259334	0.926		COBLL1	COBL-like 1
chr3_+_171183203	0.924		SEC62	SEC62 homolog (S. cerevisiae)
chr15_-_100280784	0.922	NM_001004195	OR4F4 OR4F17	olfactory receptor, family 4, subfamily F, member 4 olfactory receptor, family 4, subfamily F, member 17
chr12_-_78608873	0.919	NM_002583	PAWR	PRKC, apoptosis, WT1, regulator
chr18_+_59705918	0.918	NM_001143818 NM_002575	SERPINB2	serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr20_+_29309127	0.916	NM_001037730	DEFB115	defensin, beta 115
chr12_-_80676562	0.913		PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr10_+_90474280	0.896	NM_001080518	LIPK	lipase, family member K
chr7_+_141457977	0.896		LOC93432	maltase-glucoamylase-like pseudogene
chr2_-_215956429	0.894		FN1	fibronectin 1
chr2_+_102744921	0.894	NM_144632	TMEM182	transmembrane protein 182
chr8_+_24354387	0.888	NM_003817	ADAM7	ADAM metallopeptidase domain 7
chr5_+_139869819	0.881
chr14_-_101617680	0.869		HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1
chr11_-_77730573	0.865	NM_012296	GAB2	GRB2-associated binding protein 2
chr1_+_84402962	0.865		PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr21_-_30836051	0.846	NM_181612	KRTAP19-6	keratin associated protein 19-6
chr5_-_150663519	0.827	NM_001145017 NM_181774	SLC36A3	solute carrier family 36 (proton/amino acid symporter), member 3
chr4_-_279943	0.826	NM_001137608	ZNF732	zinc finger protein 732
chr11_-_55128424	0.824	NM_001004700	OR4C11	olfactory receptor, family 4, subfamily C, member 11
chr9_-_35860316	0.823	NM_001004487	OR13J1	olfactory receptor, family 13, subfamily J, member 1
chr3_+_129124591	0.821	NM_207335	KBTBD12	kelch repeat and BTB (POZ) domain containing 12
chr17_-_15914485	0.820		NCOR1	nuclear receptor corepressor 1
chr6_-_122807439	0.813		SERINC1	serine incorporator 1
chr12_-_14982708	0.807	NM_152321	ERP27	endoplasmic reticulum protein 27
chr13_+_52500830	0.799	NM_006418	OLFM4	olfactomedin 4
chr9_-_74757735	0.798	NM_000689	ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr5_+_76470829	0.797
chr3_-_127760447	0.793	NM_152533	C3orf22	chromosome 3 open reading frame 22
chr3_+_85858321	0.791	NM_153184	CADM2	cell adhesion molecule 2
chr11_-_62668268	0.789	NM_001136506	SLC22A24	solute carrier family 22, member 24
chr10_+_97749837	0.787	NM_001001732 NM_001159747	CC2D2B	coiled-coil and C2 domain containing 2B
chr12_+_32578513	0.784		FGD4	FYVE, RhoGEF and PH domain containing 4
chr4_-_187764213	0.776
chr6_+_97117144	0.773	NM_001170807 NM_020482	FHL5	four and a half LIM domains 5
chr18_+_74957475	0.769
chr1_-_156954528	0.762	NM_001005327	OR6K3	olfactory receptor, family 6, subfamily K, member 3
chr12_-_83954185	0.759	NM_001100917	TSPAN19	tetraspanin 19
chr5_+_179065282	0.757		CANX	calnexin
chr9_+_80134302	0.756		PSAT1	phosphoserine aminotransferase 1
chr2_+_114935623	0.754	NM_001178036	DPP10	dipeptidyl-peptidase 10 (non-functional)
chr11_+_56224436	0.753	NM_001005213 NM_001013358	OR9G1 OR9G9	olfactory receptor, family 9, subfamily G, member 1 olfactory receptor, family 9, subfamily G, member 9
chr9_+_71009746	0.751	NM_001170415 NM_001170416	TJP2	tight junction protein 2 (zona occludens 2)
chr1_+_149165438	0.751	NM_001145415 NM_012432	SETDB1	SET domain, bifurcated 1
chr9_-_85773899	0.749		HNRNPK	heterogeneous nuclear ribonucleoprotein K
chr8_+_110168828	0.747	NM_003301	TRHR	thyrotropin-releasing hormone receptor
chr2_-_207291364	0.742	NM_001093730	DYTN	dystrotelin
chr3_-_56673113	0.742	NM_015224	C3orf63	chromosome 3 open reading frame 63
chr8_-_25338472	0.739	NM_000825 NM_001083111	GNRH1	gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
chr4_-_10295412	0.739	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr11_+_89032112	0.733	NM_153696	FOLH1B	folate hydrolase 1B
chr4_-_21155376	0.730	NM_001035004	KCNIP4	Kv channel interacting protein 4
chr3_+_160473784	0.730		SCHIP1	schwannomin interacting protein 1
chr1_+_169747788	0.730		PRRC2C	proline-rich coiled-coil 2C
chr12_-_18134319	0.719	NM_024730	RERGL	RERG/RAS-like
chr9_-_21358005	0.718	NM_006900	IFNA1 IFNA13	interferon, alpha 1 interferon, alpha 13
chr4_+_71283383	0.717	NM_006685	SMR3B	submaxillary gland androgen regulated protein 3B
chr11_+_55799604	0.716	NM_001004745	OR5T1	olfactory receptor, family 5, subfamily T, member 1
chr4_+_146250978	0.715		ABCE1	ATP-binding cassette, sub-family E (OABP), member 1
chr2_+_48661229	0.714	NM_001198594	STON1 STON1-GTF2A1L	stonin 1 STON1-GTF2A1L readthrough
chr12_+_63510481	0.713
chr11_-_83661878	0.712	NM_001142700	DLG2	discs, large homolog 2 (Drosophila)
chr6_-_64087806	0.710	NM_001143940 NM_016571	LGSN	lengsin, lens protein with glutamine synthetase domain
chr21_-_26175068	0.708		APP	amyloid beta (A4) precursor protein
chr10_+_112334066	0.707		SMC3	structural maintenance of chromosomes 3
chr14_-_24148658	0.705	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr13_+_28131140	0.704	NM_015932	POMP	proteasome maturation protein
chr1_+_190871868	0.704	NM_002927 NM_144766	RGS13	regulator of G-protein signaling 13
chr5_+_147672181	0.697	NM_032566	SPINK7	serine peptidase inhibitor, Kazal type 7 (putative)
chr11_-_55942283	0.695	NM_001004744	OR5R1	olfactory receptor, family 5, subfamily R, member 1
chr19_+_21371724	0.694	NM_001076678 NM_145326 NM_175910	ZNF493	zinc finger protein 493
chrX_+_57329834	0.690	NM_174912	FAAH2	fatty acid amide hydrolase 2
chr14_+_60271203	0.688	NM_001177963 NM_002431	MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
chr15_+_46285789	0.688	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr5_+_126887056	0.683		PRRC1	proline-rich coiled-coil 1
chrX_-_131401319	0.678	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chr16_+_74868676	0.671	NM_033401	CNTNAP4	contactin associated protein-like 4
chr9_+_124416768	0.669	NM_012364	OR1Q1	olfactory receptor, family 1, subfamily Q, member 1
chr2_-_39310176	0.668	NM_001009565	CDKL4	cyclin-dependent kinase-like 4
chr5_-_58607673	0.660	NM_001197220	PDE4D	phosphodiesterase 4D, cAMP-specific
chr14_+_44622916	0.659	NM_017922	PRPF39	PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae)
chr1_-_102234959	0.658		OLFM3	olfactomedin 3
chr19_+_9157269	0.655	NM_175883	OR7D2	olfactory receptor, family 7, subfamily D, member 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
4.11	1.89e-31	GO:0007606	sensory perception of chemical stimulus
4.32	3.67e-31	GO:0007608	sensory perception of smell
2.75	2.04e-20	GO:0007600	sensory perception
1.99	6.50e-12	GO:0050877	neurological system process
1.82	1.53e-10	GO:0003008	system process
1.33	9.12e-07	GO:0032501	multicellular organismal process
1.26	2.06e-05	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.40	1.60e-08	GO:0005886	plasma membrane
1.39	3.27e-08	GO:0071944	cell periphery
1.25	6.49e-06	GO:0044425	membrane part
1.25	2.05e-04	GO:0016021	integral to membrane
1.24	3.77e-04	GO:0031224	intrinsic to membrane
1.41	2.12e-03	GO:0005576	extracellular region
1.16	3.76e-03	GO:0016020	membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
4.48	8.78e-33	GO:0004984	olfactory receptor activity
2.77	2.52e-22	GO:0004930	G-protein coupled receptor activity
2.21	1.37e-17	GO:0004888	transmembrane receptor activity
1.97	4.22e-16	GO:0004872	receptor activity
1.75	1.96e-12	GO:0004871	signal transducer activity
1.75	1.96e-12	GO:0060089	molecular transducer activity
13.61	3.32e-04	GO:0005132	interferon-alpha/beta receptor binding
3.30	1.04e-02	GO:0004867	serine-type endopeptidase inhibitor activity
8.38	1.60e-02	GO:0004522	pancreatic ribonuclease activity