Motif ID: PRRX1,2.p2

Z-value: 5.043


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PRRX2chr9_+_131467837-0.802.3e-04Click!
PRRX1chr1_+_168899936-0.292.8e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_55053398 15.428


chr7_+_113853790 11.730 NM_001172767
NM_148899
 FOXP2

forkhead box P2

chr6_+_64414389 10.829 NM_015153
 PHF3
PHD finger protein 3
chr2_-_47969350 10.278 NM_025133
 FBXO11
F-box protein 11
chr10_+_126620681 9.544 NM_017580
 ZRANB1
zinc finger, RAN-binding domain containing 1
chr7_-_26202626 9.327 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_-_55090759 9.166 NM_007008
 RTN4
reticulon 4
chr10_-_98280299 9.024 TM9SF3
transmembrane 9 superfamily member 3
chr3_-_121065112 8.505


chr2_-_206790871 8.493 NM_001098199
NM_005279
 GPR1

G protein-coupled receptor 1

chr2_-_210726539 8.464 C2orf67
chromosome 2 open reading frame 67
chr1_+_84402962 8.441 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr1_-_58920315 8.396


chr4_+_74520796 8.163 NM_001134
 AFP
alpha-fetoprotein
chr9_-_14076901 8.090 NFIB
nuclear factor I/B
chr12_+_29267863 7.663 NM_018099
 FAR2
fatty acyl CoA reductase 2
chr7_+_94135384 7.169 PEG10
paternally expressed 10
chr12_+_28301399 6.865 NM_018318
 CCDC91
coiled-coil domain containing 91
chr9_-_85773899 6.761 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr4_-_70539922 6.733 NM_001105677
 UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
2.31 1.15e-30 GO:0007608 sensory perception of smell
2.24 3.84e-31 GO:0007606 sensory perception of chemical stimulus
1.77 2.36e-22 GO:0007600 sensory perception
1.47 4.88e-14 GO:0050877 neurological system process
1.39 2.48e-12 GO:0003008 system process
1.15 4.67e-07 GO:0032501 multicellular organismal process
1.13 2.21e-06 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
enrichment   p-value GO term description
1.69 6.40e-03 GO:0005882 intermediate filament
1.58 2.70e-02 GO:0045111 intermediate filament cytoskeleton
1.16 1.18e-06 GO:0071944 cell periphery
1.16 2.37e-06 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.38 4.98e-33 GO:0004984 olfactory receptor activity
1.61 6.02e-15 GO:0004930 G-protein coupled receptor activity
1.43 1.59e-11 GO:0004888 transmembrane receptor activity
1.35 1.30e-10 GO:0004872 receptor activity
1.29 3.60e-09 GO:0004871 signal transducer activity
1.29 3.60e-09 GO:0060089 molecular transducer activity