Motif ID: SPZ1.p2

Z-value: 1.045


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_796515450.533.3e-02Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_88190737 1.411 NM_001008390
NM_003663
 CGGBP1

CGG triplet repeat binding protein 1

chr9_-_5997891 0.928 NM_001017969
 KIAA2026
KIAA2026
chr11_+_12987455 0.782 NM_001080521
 RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr12_+_50686990 0.782 NM_181711
 GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr8_+_94998258 0.758 NM_018444
NM_001161780
NM_001161779
NM_001161781
 PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr17_+_31975611 0.735 GGNBP2
gametogenetin binding protein 2
chr12_+_52665196 0.713 NM_017409
 HOXC10
homeobox C10
chr13_-_74953873 0.711 NM_014832
 TBC1D4
TBC1 domain family, member 4
chr21_+_33844793 0.705 SON
SON DNA binding protein
chr1_-_86394695 0.689 NM_152890
 COL24A1
collagen, type XXIV, alpha 1
chr10_-_104587069 0.639 NM_000102
 CYP17A1
cytochrome P450, family 17, subfamily A, polypeptide 1
chr11_+_65594361 0.633 NM_018026
 PACS1
phosphofurin acidic cluster sorting protein 1
chr12_+_63958949 0.622 NM_001193461
 MSRB3
methionine sulfoxide reductase B3
chr13_+_34414390 0.621 NM_015678
 NBEA
neurobeachin
chr17_+_35853177 0.571 NM_001552
 IGFBP4
insulin-like growth factor binding protein 4
chr20_-_21326046 0.570 NM_033176
 NKX2-4
NK2 homeobox 4
chr17_-_24973940 0.565 CORO6
coronin 6
chr17_+_2443983 0.561 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr20_+_20296744 0.555 NM_002196
 INSM1
insulinoma-associated 1
chr3_-_18441763 0.541 NM_001195470
NM_002971
 SATB1

SATB homeobox 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 73 entries
enrichment   p-value GO term description
1.93 4.84e-03 GO:0010720 positive regulation of cell development
1.69 4.98e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.68 3.45e-03 GO:0045664 regulation of neuron differentiation
1.63 2.01e-03 GO:0050767 regulation of neurogenesis
1.58 2.89e-04 GO:0007411 axon guidance
1.57 3.80e-06 GO:0048812 neuron projection morphogenesis
1.57 1.22e-05 GO:0007409 axonogenesis
1.55 1.35e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.55 2.28e-03 GO:0060284 regulation of cell development
1.54 5.04e-06 GO:0031175 neuron projection development
1.53 3.67e-07 GO:0048666 neuron development
1.53 6.77e-06 GO:0000904 cell morphogenesis involved in differentiation
1.53 2.36e-02 GO:0051960 regulation of nervous system development
1.52 2.23e-11 GO:0048699 generation of neurons
1.52 7.54e-06 GO:0048858 cell projection morphogenesis
1.52 8.39e-06 GO:0032990 cell part morphogenesis
1.52 1.01e-02 GO:0022603 regulation of anatomical structure morphogenesis
1.50 6.07e-11 GO:0022008 neurogenesis
1.50 5.07e-08 GO:0030182 neuron differentiation
1.48 7.98e-06 GO:0000902 cell morphogenesis

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.73 3.68e-02 GO:0030055 cell-substrate junction
1.65 1.37e-02 GO:0005912 adherens junction
1.60 2.57e-02 GO:0070161 anchoring junction
1.40 1.55e-04 GO:0030054 cell junction
1.22 1.35e-03 GO:0005856 cytoskeleton
1.08 2.09e-04 GO:0005737 cytoplasm
1.05 9.57e-04 GO:0044424 intracellular part
1.05 2.32e-03 GO:0005622 intracellular
1.03 4.38e-02 GO:0044464 cell part
1.03 4.60e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.27 1.85e-02 GO:0046332 SMAD binding
1.47 9.91e-03 GO:0016563 transcription activator activity
1.44 6.63e-03 GO:0000988 protein binding transcription factor activity
1.44 6.63e-03 GO:0000989 transcription factor binding transcription factor activity
1.43 9.66e-03 GO:0003712 transcription cofactor activity
1.42 3.59e-03 GO:0019904 protein domain specific binding
1.28 2.68e-02 GO:0016301 kinase activity
1.13 1.65e-10 GO:0005515 protein binding
1.04 2.37e-02 GO:0005488 binding