Motif ID: GLI1..3.p2

Z-value: 2.357


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
GLI1 2735 glioma-associated oncogene homolog 1 (zinc finger protein)
GLI2 2736 GLI-Kruppel family member GLI2
GLI3 2737 GLI-Kruppel family member GLI3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GLI3chr7_-_422431420.639.0e-03Click!
GLI2chr2_+_1212713360.514.4e-02Click!
GLI1chr12_+_561401840.458.2e-02Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_566482 6.628 NM_020901
 PHRF1
PHD and ring finger domains 1
chr16_+_2461500 2.748 NM_006181
 NTN3
netrin 3
chr7_-_100009205 2.537 NM_001168682
 SAP25
sin3A-binding protein 25
chr15_+_65217412 2.504 NM_001145103
 SMAD3
SMAD family member 3
chr4_+_1764802 2.456 NM_000142
NM_001163213
NM_022965
 FGFR3


fibroblast growth factor receptor 3


chr1_+_148090804 2.323 NM_021059
NM_001005464
 HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr11_-_72057755 2.297 NM_001146209
 PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr11_+_1848674 2.216 NM_001013254
NM_001013255
 LSP1

lymphocyte-specific protein 1

chr22_+_18090118 2.067 SEPT5-GP1BB
SEPT5-GP1BB read-through transcript
chr13_+_112789669 2.040 MCF2L
MCF.2 cell line derived transforming sequence-like
chr22_-_17892001 2.033 CLDN5
claudin 5
chr12_+_110328126 2.029 NM_005475
 SH2B3
SH2B adaptor protein 3
chr11_+_76491532 1.946 NM_006189
 OMP
olfactory marker protein
chr19_-_51010272 1.936 NM_030785
 RSPH6A
radial spoke head 6 homolog A (Chlamydomonas)
chr11_-_404975 1.935 NM_001135054
 SIGIRR
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr16_+_2138608 1.898 NM_014353
 RAB26
RAB26, member RAS oncogene family
chr6_-_34209250 1.869 NM_000841
 GRM4
glutamate receptor, metabotropic 4
chr5_+_176170041 1.803 NM_133369
 UNC5A
unc-5 homolog A (C. elegans)
chr19_+_482737 1.803 CDC34
cell division cycle 34 homolog (S. cerevisiae)
chr19_+_3490154 1.794 NM_001135580
 C19orf71
chromosome 19 open reading frame 71

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 27 entries
enrichment   p-value GO term description
1.77 4.91e-02 GO:0046578 regulation of Ras protein signal transduction
1.69 5.05e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.59 4.01e-02 GO:0007409 axonogenesis
1.49 4.06e-04 GO:0048699 generation of neurons
1.47 1.59e-02 GO:0030182 neuron differentiation
1.45 1.52e-03 GO:0022008 neurogenesis
1.44 1.99e-06 GO:0009966 regulation of signal transduction
1.41 1.32e-06 GO:0023051 regulation of signaling
1.39 2.93e-02 GO:0048468 cell development
1.37 1.78e-04 GO:0009653 anatomical structure morphogenesis
1.37 2.36e-04 GO:0007399 nervous system development
1.37 1.87e-02 GO:0010646 regulation of cell communication
1.36 5.26e-06 GO:0048583 regulation of response to stimulus
1.36 4.77e-02 GO:0007154 cell communication
1.30 3.65e-02 GO:0065009 regulation of molecular function
1.29 6.10e-04 GO:0048869 cellular developmental process
1.29 9.24e-04 GO:0030154 cell differentiation
1.25 2.92e-04 GO:0048731 system development
1.23 1.54e-02 GO:0048522 positive regulation of cellular process
1.22 9.46e-04 GO:0048856 anatomical structure development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.80 4.89e-04 GO:0005083 small GTPase regulator activity
1.73 1.34e-02 GO:0005096 GTPase activator activity
1.54 1.01e-02 GO:0030695 GTPase regulator activity
1.50 2.99e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.45 7.64e-03 GO:0043565 sequence-specific DNA binding
1.13 6.40e-05 GO:0005515 protein binding