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Motif ID: RREB1.p2

Z-value: 4.720

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_191232653	10.822	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr10_+_135343649	10.235	NM_012147	DUX2	double homeobox 2
chr10_+_135333667	8.990	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr10_+_135330357	8.836	NM_033178 NM_012147 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191235959	8.638	NM_001177376	DUX4L4	double homeobox 4 like 4
chr4_-_809879	8.053	NM_006651	CPLX1	complexin 1
chr4_+_191239247	7.910	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr4_+_191229360	7.730	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr14_+_104244998	7.668		INF2	inverted formin, FH2 and WH2 domain containing
chr4_+_191226073	7.578	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr1_-_30977931	7.270		LAPTM5	lysosomal protein transmembrane 5
chr19_+_540849	7.194	NM_001194	HCN2	hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_-_96924582	6.380	NM_001172667	FAM178B	family with sequence similarity 178, member B
chr4_+_191242540	5.613	NM_033178 NM_012147 NM_001177376 NM_001127387 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L7 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 7 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr11_+_56984702	5.324	NM_178570	RTN4RL2	reticulon 4 receptor-like 2
chr1_+_1066138	5.320
chr20_-_61574259	5.293	NM_004518 NM_172106 NM_172107 NM_172108 NM_172109	KCNQ2	potassium voltage-gated channel, KQT-like subfamily, member 2
chr21_+_42946719	5.215	NM_001001567 NM_001001568 NM_001001569 NM_001001570 NM_001001571 NM_001001572 NM_001001573 NM_001001574 NM_001001575 NM_001001576 NM_001001577 NM_001001578 NM_001001579 NM_001001580 NM_001001581 NM_001001582 NM_001001583 NM_001001584 NM_001001585 NM_002606	PDE9A	phosphodiesterase 9A
chr2_-_128149112	5.171	NM_001136037 NM_001161403	LIMS2	LIM and senescent cell antigen-like domains 2
chr1_+_1940605	4.880	NM_000815	GABRD	gamma-aminobutyric acid (GABA) A receptor, delta
chr8_+_145461356	4.320	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr2_+_72998111	4.255	NM_004097	EMX1	empty spiracles homeobox 1
chrX_+_151617900	4.093	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chr20_-_26137755	3.975		LOC284801	hypothetical protein LOC284801
chr11_-_404975	3.932	NM_001135054	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr1_+_945331	3.931	NM_198576	AGRN	agrin
chr4_+_191245840	3.798	NM_033178 NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467 NM_001127386	DUX4 DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3 DUX4L2	double homeobox 4 double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3 double homeobox 4 like 2
chr19_+_40213431	3.582	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr8_-_145119627	3.499	NM_201378	PLEC	plectin
chrX_+_151633730	3.494	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chr20_-_47618059	3.473	NM_000961	PTGIS	prostaglandin I2 (prostacyclin) synthase
chr11_+_66939720	3.444	NM_001166222 NM_020811	CARNS1	carnosine synthase 1
chr9_+_138997265	3.412	NM_207510	LCNL1	lipocalin-like 1
chr20_+_44070946	3.390	NM_004994	MMP9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr19_+_54786723	3.386	NM_020719	PRR12	proline rich 12
chrX_+_148671394	3.377	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr7_+_100111689	3.337		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_135161185	3.324	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr3_-_50515857	3.279	NM_001005505 NM_001174051 NM_006030	CACNA2D2	calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr17_-_75427644	3.263	NM_003655	CBX4	chromobox homolog 4
chr16_+_2068186	3.207		TSC2	tuberous sclerosis 2
chr2_-_218551786	3.182		TNS1	tensin 1
chr10_-_103525646	3.052	NM_006119 NM_033163 NM_033164 NM_033165	FGF8	fibroblast growth factor 8 (androgen-induced)
chr14_+_105012106	3.051	NM_001312	CRIP2	cysteine-rich protein 2
chr1_+_3378030	3.047		ARHGEF16	Rho guanine nucleotide exchange factor (GEF) 16
chr20_-_62151216	3.016	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr19_+_45996881	3.009	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chrX_-_100759562	3.005	NM_001009584 NM_001184768 NM_019007	ARMCX6	armadillo repeat containing, X-linked 6
chr9_+_129962292	2.949	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr7_-_100331417	2.945	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr17_-_44047299	2.908	NM_024016	HOXB8	homeobox B8
chr12_-_131816604	2.907		ANKLE2	ankyrin repeat and LEM domain containing 2
chr3_-_48607596	2.868	NM_000094	COL7A1	collagen, type VII, alpha 1
chrX_+_119379967	2.847	NM_001142447 NM_012069	ATP1B4	ATPase, Na+/K+ transporting, beta 4 polypeptide
chr22_+_48966394	2.843		TRABD	TraB domain containing
chr1_+_945399	2.840
chr9_+_138341752	2.836	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr12_-_7153068	2.806	NM_016546	C1RL	complement component 1, r subcomponent-like
chr1_+_945472	2.796		AGRN	agrin
chr14_+_102458745	2.741	NM_030943	AMN	amnionless homolog (mouse)
chr10_-_135000464	2.739	NM_015722	CALY	calcyon neuron-specific vesicular protein
chr16_-_53520208	2.651		CRNDE	colorectal neoplasia differentially expressed (non-protein coding)
chr11_-_1731273	2.649
chr22_+_49333327	2.627	NM_138433	KLHDC7B	kelch domain containing 7B
chr2_+_233443237	2.618	NM_206895	C2orf82	chromosome 2 open reading frame 82
chr17_-_60208083	2.580		LOC146880	hypothetical LOC146880
chr11_+_359723	2.570	NM_178537	B4GALNT4	beta-1,4-N-acetyl-galactosaminyl transferase 4
chr21_+_43985728	2.568		PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr2_+_20729904	2.536	NM_182828	GDF7	growth differentiation factor 7
chrX_-_39841599	2.518	NM_001123385 NM_017745	BCOR	BCL6 corepressor
chr2_-_128149800	2.501		LIMS2	LIM and senescent cell antigen-like domains 2
chr12_+_4253143	2.466	NM_001759	CCND2	cyclin D2
chr22_+_48966480	2.447	NM_025204	TRABD	TraB domain containing
chr3_-_12983959	2.429	NM_014869	IQSEC1	IQ motif and Sec7 domain 1
chr12_+_52665196	2.427	NM_017409	HOXC10	homeobox C10
chr1_-_1525309	2.411		LOC643988	hypothetical LOC643988
chr22_-_30929463	2.404	NM_001098527	RFPL2	ret finger protein-like 2
chr10_-_98935652	2.398	NM_003061	SLIT1	slit homolog 1 (Drosophila)
chr18_+_75261231	2.395	NM_172387 NM_172389	NFATC1	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr17_+_71975224	2.385	NM_001088	AANAT	aralkylamine N-acetyltransferase
chr8_-_145530639	2.382	NM_031309	SCRT1	scratch homolog 1, zinc finger protein (Drosophila)
chr8_-_41624030	2.321	NM_152568	NKX6-3	NK6 homeobox 3
chrX_+_46967360	2.317	NM_001170460	CDK16	cyclin-dependent kinase 16
chr10_-_135000358	2.304		CALY	calcyon neuron-specific vesicular protein
chr9_+_139006663	2.300	NM_183241	C9orf142	chromosome 9 open reading frame 142
chr11_-_1007140	2.283		MUC6	mucin 6, oligomeric mucus/gel-forming
chr19_+_12995782	2.278		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr19_+_7891884	2.277		SNAPC2	small nuclear RNA activating complex, polypeptide 2, 45kDa
chr8_+_145393450	2.274	NM_001008271 NM_001080514	SCXA SCXB	scleraxis homolog A (mouse) scleraxis homolog B (mouse)
chr11_-_8695974	2.257		ST5	suppression of tumorigenicity 5
chr19_-_7896974	2.247	NM_206833	CTXN1	cortexin 1
chrX_+_134383533	2.210		NCRNA00086	non-protein coding RNA 86
chrX_-_153534951	2.204	NM_020994 NM_172377	CTAG2	cancer/testis antigen 2
chr4_-_154929657	2.199	NM_003013	SFRP2	secreted frizzled-related protein 2
chr7_+_45163891	2.197	NM_005856	RAMP3	receptor (G protein-coupled) activity modifying protein 3
chr7_+_100111712	2.190		GNB2	guanine nucleotide binding protein (G protein), beta polypeptide 2
chr11_-_72031083	2.187	NM_001143839	PDE2A	phosphodiesterase 2A, cGMP-stimulated
chr8_-_144583718	2.186	NM_201589	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr21_-_45173061	2.155	NM_001127491	ITGB2	integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr3_-_185578621	2.143	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr9_+_138760432	2.124		LOC100128593	hypothetical LOC100128593
chr11_-_76058542	2.116	NM_005512	LRRC32	leucine rich repeat containing 32
chr11_+_183079	2.106	NM_145651	SCGB1C1	secretoglobin, family 1C, member 1
chr17_+_72982919	2.104	NM_001113495	SEPT9	septin 9
chr1_+_18830086	2.089	NM_001135254 NM_002584 NM_013945	PAX7	paired box 7
chr21_+_44699796	2.068	NM_030891	LRRC3	leucine rich repeat containing 3
chr14_+_104267270	2.058	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr19_+_45996940	2.055		EGLN2	egl nine homolog 2 (C. elegans)
chr11_+_10283171	2.049	NM_001124	ADM	adrenomedullin
chr10_-_88116181	2.036	NM_017551	GRID1	glutamate receptor, ionotropic, delta 1
chr8_+_144870482	2.035	NM_139021	MAPK15	mitogen-activated protein kinase 15
chrX_-_74062005	2.021	NM_001008537	KIAA2022	KIAA2022
chr4_+_995395	2.009		FGFRL1	fibroblast growth factor receptor-like 1
chr11_+_279113	2.002	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr7_+_5609416	2.000		FSCN1	fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr1_+_2975590	1.996	NM_022114 NM_199454	PRDM16	PR domain containing 16
chr21_+_44560779	1.994		PFKL	phosphofructokinase, liver
chrX_+_102471769	1.980	NM_152278	TCEAL7	transcription elongation factor A (SII)-like 7
chr14_+_104261578	1.972	NM_152328	ADSSL1	adenylosuccinate synthase like 1
chr7_-_4965270	1.939	NM_001100600 NM_198403	MMD2	monocyte to macrophage differentiation-associated 2
chr6_+_33486750	1.937	NM_002636 NM_024165	PHF1	PHD finger protein 1
chr9_+_76302071	1.927	NM_006914	RORB	RAR-related orphan receptor B
chr19_+_659766	1.922	NM_001040134 NM_002579	PALM	paralemmin
chr19_+_811615	1.916		CFD	complement factor D (adipsin)
chr19_-_51168396	1.914	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr12_+_130878870	1.913	NM_016155	MMP17	matrix metallopeptidase 17 (membrane-inserted)
chr17_-_45562112	1.897	NM_174920	SAMD14	sterile alpha motif domain containing 14
chr4_+_995609	1.895	NM_001004356 NM_001004358	FGFRL1	fibroblast growth factor receptor-like 1
chr22_-_49240594	1.864		SBF1	SET binding factor 1
chr17_+_35751796	1.864	NM_001024809	RARA	retinoic acid receptor, alpha
chr9_-_129564517	1.863	NM_001142532 NM_001142531	SH2D3C	SH2 domain containing 3C
chr11_-_133786935	1.859	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr11_-_66961709	1.858	NM_005608	PTPRCAP	protein tyrosine phosphatase, receptor type, C-associated protein
chr19_-_60557875	1.858	NM_144613	COX6B2	cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr16_+_1062756	1.856	NM_001172560	SSTR5	somatostatin receptor 5
chr9_-_139068269	1.848	NM_001246 NM_203468	ENTPD2	ectonucleoside triphosphate diphosphohydrolase 2
chr18_+_42168180	1.843	NM_152470	C18orf23 RNF165	chromosome 18 open reading frame 23 ring finger protein 165
chr17_+_58908152	1.836	NM_000789	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chr17_+_39741306	1.835	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chrX_-_148476903	1.832	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr19_+_54299686	1.831		SNRNP70	small nuclear ribonucleoprotein 70kDa (U1)
chr8_-_82916982	1.827	NM_022133 NM_152836 NM_152837	SNX16	sorting nexin 16
chr9_+_132529801	1.821	NM_021619	PRDM12	PR domain containing 12
chr19_+_60487345	1.821	NM_032430	BRSK1	BR serine/threonine kinase 1
chr7_-_44331544	1.808	NM_001220 NM_172078 NM_172079 NM_172080 NM_172081 NM_172082 NM_172083 NM_172084	CAMK2B	calcium/calmodulin-dependent protein kinase II beta
chr1_-_200879203	1.803	NM_001136504	SYT2	synaptotagmin II
chr19_-_1989937	1.801		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr22_+_28446288	1.792	NM_182527	CABP7	calcium binding protein 7
chrX_-_137621492	1.787	NM_004114	FGF13	fibroblast growth factor 13
chr19_+_1055007	1.787		GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr4_-_109308893	1.780	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr1_+_968522	1.779		AGRN	agrin
chr10_-_98935570	1.776		SLIT1	slit homolog 1 (Drosophila)
chr22_+_17337970	1.774		DGCR5	DiGeorge syndrome critical region gene 5 (non-protein coding)
chrX_+_151975518	1.774		PNMA3	paraneoplastic antigen MA3
chr15_+_72687765	1.770	NM_003992	CLK3	CDC-like kinase 3
chr1_-_47468029	1.764	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr19_+_13111072	1.756		NACC1	nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr8_-_145725289	1.756		C8orf82	chromosome 8 open reading frame 82
chr11_-_1006736	1.753		MUC6	mucin 6, oligomeric mucus/gel-forming
chr17_-_6400470	1.752	NM_001165966 NM_031220	PITPNM3	PITPNM family member 3
chr19_+_60691671	1.752	NM_001144950 NM_001195267	SSC5D	scavenger receptor cysteine rich domain containing (5 domains)
chr5_-_1397941	1.750	NM_030782	CLPTM1L	CLPTM1-like
chr17_+_62391216	1.727	NM_014405	CACNG4	calcium channel, voltage-dependent, gamma subunit 4
chr19_-_360138	1.719	NM_001136263	C2CD4C	C2 calcium-dependent domain containing 4C
chr11_+_566482	1.707	NM_020901	PHRF1	PHD and ring finger domains 1
chr8_-_139995417	1.705	NM_152888	COL22A1	collagen, type XXII, alpha 1
chr15_+_38430517	1.695	NM_001145643	PHGR1	proline/histidine/glycine-rich 1
chr3_-_42719322	1.692	NM_020707	HHATL	hedgehog acyltransferase-like
chr19_-_15421761	1.691	NM_021241	WIZ	widely interspaced zinc finger motifs
chr21_-_43368963	1.687	NM_000071	CBS	cystathionine-beta-synthase
chr11_+_45863774	1.687	NM_005456	MAPK8IP1	mitogen-activated protein kinase 8 interacting protein 1
chr9_-_100510657	1.685	NM_005458	GABBR2	gamma-aminobutyric acid (GABA) B receptor, 2
chrX_+_51944658	1.683	NM_001098800 NM_030801 NM_177535 NM_177537	MAGED4 MAGED4B	melanoma antigen family D, 4 melanoma antigen family D, 4B
chr11_+_124539768	1.678	NM_022062	PKNOX2	PBX/knotted 1 homeobox 2
chr22_+_35777561	1.672	NM_024681	KCTD17	potassium channel tetramerisation domain containing 17
chr1_-_16812274	1.666	NM_017940	NBPF1	neuroblastoma breakpoint family, member 1
chr19_+_1055614	1.664	NM_001039848	GPX4	glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr12_+_52634950	1.663	NM_173860	HOXC12	homeobox C12
chr11_+_63864263	1.661	NM_032251	CCDC88B	coiled-coil domain containing 88B
chr7_-_75794919	1.658		YWHAG	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr12_+_6179736	1.653	NM_001769	CD9	CD9 molecule
chr19_+_13924318	1.650	NM_138353	DCAF15	DDB1 and CUL4 associated factor 15
chr17_+_75507750	1.647
chr4_-_8180278	1.641		ABLIM2	actin binding LIM protein family, member 2
chr1_-_1465602	1.634	NM_001114748	C1orf70	chromosome 1 open reading frame 70
chr2_+_218833982	1.623	NM_001077191 NM_001077194 NM_170699	GPBAR1	G protein-coupled bile acid receptor 1
chr7_+_73341640	1.619	NM_003388 NM_032421	CLIP2	CAP-GLY domain containing linker protein 2
chr7_-_101906311	1.619	NM_006234	POLR2J2 POLR2J	polymerase (RNA) II (DNA directed) polypeptide J2 polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr10_-_103589586	1.618	NM_173194	KCNIP2	Kv channel interacting protein 2
chr17_-_44010543	1.612	NM_024015	HOXB4	homeobox B4
chr14_-_64508547	1.609	NM_198686	RAB15	RAB15, member RAS onocogene family
chr12_+_6807831	1.607	NM_014262	LEPREL2	leprecan-like 2
chr16_+_1143738	1.606		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr17_-_44058612	1.605	NM_024017	HOXB9	homeobox B9
chrX_+_151975421	1.603	NM_013364	PNMA3	paraneoplastic antigen MA3
chr6_+_32515596	1.600	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chrX_-_99778340	1.592	NM_003270	TSPAN6	tetraspanin 6
chr9_-_129729518	1.592	NM_173492	PIP5KL1	phosphatidylinositol-4-phosphate 5-kinase-like 1
chrX_+_23262905	1.592	NM_173495	PTCHD1	patched domain containing 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.51	6.50e-17	GO:0007399	nervous system development
1.34	3.60e-16	GO:0048731	system development
1.31	4.99e-16	GO:0048856	anatomical structure development
1.29	1.51e-15	GO:0007275	multicellular organismal development
1.27	6.96e-15	GO:0032502	developmental process
1.15	4.31e-14	GO:0065007	biological regulation
1.38	2.26e-13	GO:0030154	cell differentiation
1.37	4.03e-13	GO:0048869	cellular developmental process
1.59	4.63e-13	GO:0022008	neurogenesis
1.60	8.58e-13	GO:0048699	generation of neurons
1.66	3.40e-12	GO:0030182	neuron differentiation
1.54	7.27e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.37	8.49e-12	GO:0048513	organ development
1.14	1.46e-10	GO:0050789	regulation of biological process
1.53	1.77e-10	GO:0048468	cell development
1.14	1.03e-09	GO:0050794	regulation of cellular process
1.39	1.19e-09	GO:0009653	anatomical structure morphogenesis
1.54	9.35e-09	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	1.75e-08	GO:0048518	positive regulation of biological process
1.53	2.07e-08	GO:0051173	positive regulation of nitrogen compound metabolic process
1.56	3.17e-08	GO:0010628	positive regulation of gene expression
1.56	3.21e-08	GO:0045595	regulation of cell differentiation
1.26	5.24e-08	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64	1.01e-07	GO:0007417	central nervous system development
1.66	1.08e-07	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.25	1.19e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.27	1.62e-07	GO:0048519	negative regulation of biological process
1.54	2.80e-07	GO:0051254	positive regulation of RNA metabolic process
1.28	4.02e-07	GO:0048523	negative regulation of cellular process
1.52	4.56e-07	GO:0009790	embryo development
1.26	6.52e-07	GO:0048522	positive regulation of cellular process
1.46	9.03e-07	GO:0009888	tissue development
1.54	1.41e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.44	1.52e-06	GO:0050793	regulation of developmental process
1.76	2.15e-06	GO:0060284	regulation of cell development
1.55	2.35e-06	GO:0048666	neuron development
1.18	2.56e-06	GO:0019222	regulation of metabolic process
1.26	2.59e-06	GO:0051252	regulation of RNA metabolic process
1.36	3.56e-06	GO:0009893	positive regulation of metabolic process
1.19	4.32e-06	GO:0080090	regulation of primary metabolic process
1.59	4.76e-06	GO:0000904	cell morphogenesis involved in differentiation
1.19	5.11e-06	GO:0031323	regulation of cellular metabolic process
1.53	7.21e-06	GO:0009887	organ morphogenesis
1.37	8.05e-06	GO:0010604	positive regulation of macromolecule metabolic process
1.46	8.47e-06	GO:0007267	cell-cell signaling
1.62	1.19e-05	GO:0007409	axonogenesis
1.57	1.45e-05	GO:0031175	neuron projection development
1.51	1.75e-05	GO:0010629	negative regulation of gene expression
1.60	1.84e-05	GO:0048667	cell morphogenesis involved in neuron differentiation
1.42	2.19e-05	GO:0031328	positive regulation of cellular biosynthetic process
1.35	2.22e-05	GO:0031325	positive regulation of cellular metabolic process
1.42	2.35e-05	GO:0009891	positive regulation of biosynthetic process
1.59	3.15e-05	GO:0048812	neuron projection morphogenesis
1.53	3.53e-05	GO:0051253	negative regulation of RNA metabolic process
1.65	3.68e-05	GO:0007420	brain development
1.24	3.86e-05	GO:0006355	regulation of transcription, DNA-dependent
1.53	4.70e-05	GO:0045892	negative regulation of transcription, DNA-dependent
1.14	5.36e-05	GO:0032501	multicellular organismal process
1.64	6.43e-05	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.21	7.18e-05	GO:0031326	regulation of cellular biosynthetic process
1.37	7.44e-05	GO:0007154	cell communication
1.43	8.22e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.32	1.10e-04	GO:0051239	regulation of multicellular organismal process
1.21	1.28e-04	GO:0009889	regulation of biosynthetic process
1.71	1.63e-04	GO:0051960	regulation of nervous system development
1.84	1.68e-04	GO:0045664	regulation of neuron differentiation
1.75	1.81e-04	GO:0050767	regulation of neurogenesis
1.56	2.09e-04	GO:0007268	synaptic transmission
1.55	2.45e-04	GO:0032583	regulation of gene-specific transcription
1.58	2.51e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.18	2.65e-04	GO:0060255	regulation of macromolecule metabolic process
1.52	2.70e-04	GO:0019226	transmission of nerve impulse
1.52	2.70e-04	GO:0035637	multicellular organismal signaling
1.47	2.95e-04	GO:0000902	cell morphogenesis
1.69	3.48e-04	GO:0061061	muscle structure development
1.51	3.64e-04	GO:0048858	cell projection morphogenesis
1.16	3.71e-04	GO:0023052	signaling
1.21	3.90e-04	GO:0010468	regulation of gene expression
1.71	4.18e-04	GO:0045596	negative regulation of cell differentiation
1.46	4.32e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.59	5.04e-04	GO:0043009	chordate embryonic development
1.62	5.67e-04	GO:0007411	axon guidance
1.44	5.94e-04	GO:0030030	cell projection organization
1.45	6.30e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
1.49	6.46e-04	GO:0032990	cell part morphogenesis
1.40	6.60e-04	GO:2000026	regulation of multicellular organismal development
2.30	7.15e-04	GO:0021953	central nervous system neuron differentiation
1.90	7.43e-04	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.80	9.80e-04	GO:0032582	negative regulation of gene-specific transcription
1.57	9.81e-04	GO:0009792	embryo development ending in birth or egg hatching
1.41	1.26e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.41	1.35e-03	GO:0009890	negative regulation of biosynthetic process
1.42	1.69e-03	GO:0032989	cellular component morphogenesis
1.56	1.82e-03	GO:0048598	embryonic morphogenesis
1.82	2.28e-03	GO:0030900	forebrain development
1.96	2.31e-03	GO:0030799	regulation of cyclic nucleotide metabolic process
1.61	2.98e-03	GO:0048729	tissue morphogenesis
1.20	3.06e-03	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.20	3.89e-03	GO:0042221	response to chemical stimulus
1.57	4.71e-03	GO:0051093	negative regulation of developmental process
1.56	5.01e-03	GO:0007389	pattern specification process
1.40	5.29e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.61	6.26e-03	GO:0007423	sensory organ development
1.74	6.34e-03	GO:0007517	muscle organ development
1.31	6.59e-03	GO:0009892	negative regulation of metabolic process
1.22	6.83e-03	GO:0007166	cell surface receptor linked signaling pathway
1.81	7.41e-03	GO:0006813	potassium ion transport
1.33	7.74e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.24	9.02e-03	GO:0023051	regulation of signaling
1.18	1.08e-02	GO:0010556	regulation of macromolecule biosynthetic process
3.15	1.09e-02	GO:0071300	cellular response to retinoic acid
1.31	1.13e-02	GO:0009605	response to external stimulus
1.39	1.21e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.32	1.51e-02	GO:0031324	negative regulation of cellular metabolic process
1.89	1.77e-02	GO:0030802	regulation of cyclic nucleotide biosynthetic process
1.89	1.77e-02	GO:0030808	regulation of nucleotide biosynthetic process
2.75	2.25e-02	GO:0051925	regulation of calcium ion transport via voltage-gated calcium channel activity
3.03	2.29e-02	GO:0071299	cellular response to vitamin A
1.05	2.32e-02	GO:0009987	cellular process
1.63	2.83e-02	GO:0002009	morphogenesis of an epithelium
1.46	2.94e-02	GO:0040008	regulation of growth
1.62	3.02e-02	GO:0003002	regionalization
1.19	3.84e-02	GO:0065008	regulation of biological quality
1.61	4.19e-02	GO:0048568	embryonic organ development
1.31	4.49e-02	GO:0040011	locomotion
1.95	4.98e-02	GO:0045761	regulation of adenylate cyclase activity

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.26	3.63e-07	GO:0044459	plasma membrane part
2.00	2.60e-05	GO:0034703	cation channel complex
1.75	1.20e-04	GO:0034702	ion channel complex
1.43	2.00e-04	GO:0030054	cell junction
1.53	2.00e-04	GO:0045202	synapse
1.13	1.40e-03	GO:0005886	plasma membrane
2.04	3.45e-03	GO:0008076	voltage-gated potassium channel complex
2.04	3.45e-03	GO:0034705	potassium channel complex
1.12	3.86e-03	GO:0071944	cell periphery
1.46	3.93e-03	GO:0043005	neuron projection
2.12	5.72e-03	GO:0042383	sarcolemma
1.53	6.24e-03	GO:0044456	synapse part
1.22	4.98e-02	GO:0031226	intrinsic to plasma membrane

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.73	2.54e-16	GO:0043565	sequence-specific DNA binding
1.54	4.25e-13	GO:0001071	nucleic acid binding transcription factor activity
1.54	4.25e-13	GO:0003700	sequence-specific DNA binding transcription factor activity
1.49	3.82e-11	GO:0030528	transcription regulator activity
1.83	1.89e-07	GO:0005261	cation channel activity
1.11	7.81e-07	GO:0005515	protein binding
2.11	8.05e-07	GO:0022843	voltage-gated cation channel activity
1.59	1.69e-05	GO:0022838	substrate-specific channel activity
1.87	2.06e-05	GO:0005244	voltage-gated ion channel activity
1.87	2.06e-05	GO:0022832	voltage-gated channel activity
1.58	4.37e-05	GO:0005216	ion channel activity
1.55	6.42e-05	GO:0015267	channel activity
1.55	7.52e-05	GO:0022803	passive transmembrane transporter activity
1.63	1.00e-04	GO:0022836	gated channel activity
1.99	1.98e-04	GO:0005267	potassium channel activity
1.75	3.12e-04	GO:0000975	regulatory region DNA binding
1.75	3.12e-04	GO:0001067	regulatory region nucleic acid binding
1.75	3.12e-04	GO:0044212	transcription regulatory region DNA binding
1.75	6.00e-04	GO:0010843	promoter binding
1.54	4.33e-03	GO:0016564	transcription repressor activity
1.52	5.97e-03	GO:0016563	transcription activator activity
1.96	8.65e-03	GO:0005249	voltage-gated potassium channel activity
1.31	3.11e-02	GO:0015075	ion transmembrane transporter activity