Motif ID: TGIF1.p2

Z-value: 1.232


Transcription factors associated with TGIF1.p2:

Gene SymbolEntrez IDGene Name
TGIF1 7050 TGFB-induced factor homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TGIF1chr18_+_3441589-0.533.6e-02Click!


Activity profile for motif TGIF1.p2.

activity profile for motif TGIF1.p2


Sorted Z-values histogram for motif TGIF1.p2

Sorted Z-values for motif TGIF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TGIF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_143750988 1.828 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr9_-_33437527 1.660 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr13_-_49597776 1.361 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr6_+_32515596 1.234 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr14_-_22974707 0.988 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr2_+_96566190 0.969 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr21_+_33844793 0.943 SON
SON DNA binding protein
chr1_+_246150942 0.942 NM_001005522
OR2T8
olfactory receptor, family 2, subfamily T, member 8
chr1_+_78858675 0.932 NM_006820
IFI44L
interferon-induced protein 44-like
chr6_-_32121784 0.918 NM_032470
TNXB
tenascin XB
chr18_+_59295123 0.912 NM_002639
SERPINB5
serpin peptidase inhibitor, clade B (ovalbumin), member 5
chr3_+_114733907 0.846 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr2_-_191580567 0.765 STAT1
signal transducer and activator of transcription 1, 91kDa
chr9_-_16717887 0.726 BNC2
basonuclin 2
chr10_-_21847126 0.719


chr16_-_56389176 0.712 NM_001130099
KIFC3
kinesin family member C3
chr13_+_77007809 0.707 NM_001160706
NM_003843
NM_144777
SCEL


sciellin


chr22_+_38652555 0.702 GRAP2
GRB2-related adaptor protein 2
chrX_+_110074124 0.681 NM_001128166
NM_001128167
PAK3

p21 protein (Cdc42/Rac)-activated kinase 3

chr22_-_41158306 0.666 NM_145912
NFAM1
NFAT activating protein with ITAM motif 1
chr8_+_42671718 0.635 NM_000749
CHRNB3
cholinergic receptor, nicotinic, beta 3
chr3_-_130807865 0.624 NM_015103
PLXND1
plexin D1
chr16_-_54547443 0.621 NM_001190158
CES5A
carboxylesterase 5A
chr10_+_99339344 0.612 NM_001009997
C10orf62
chromosome 10 open reading frame 62
chr17_-_36915329 0.608 NM_002274
NM_153490
KRT13

keratin 13

chr17_-_29714293 0.597 NM_002981
CCL1
chemokine (C-C motif) ligand 1
chr17_+_70540265 0.595 KCTD2
potassium channel tetramerisation domain containing 2
chr9_+_34642125 0.588 NM_001142784
IL11RA
interleukin 11 receptor, alpha
chr5_-_54317102 0.585 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr3_-_192063158 0.579 NM_001146686
GEMC1
geminin coiled-coil domain-containing protein 1
chr11_-_83071084 0.570 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr19_-_43926953 0.565 NM_144691
CAPN12
calpain 12
chr3_+_171112053 0.562 NM_182610
SAMD7
sterile alpha motif domain containing 7
chr2_+_233633348 0.562 INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr4_-_122304925 0.555 NM_024873
TNIP3
TNFAIP3 interacting protein 3
chr2_+_223625105 0.555 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr5_-_58607673 0.547 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chrX_-_32340291 0.542 NM_004011
NM_004012
DMD

dystrophin

chr5_-_20024050 0.540 NM_001167667
NM_004934
CDH18

cadherin 18, type 2

chr2_+_233633279 0.539 NM_001017915
NM_005541
INPP5D

inositol polyphosphate-5-phosphatase, 145kDa

chr18_+_19947314 0.526 TTC39C
tetratricopeptide repeat domain 39C
chr10_+_104525877 0.525 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr18_+_64616296 0.524 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr2_+_216695062 0.515 XRCC5
X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
chr11_-_76059435 0.503 NM_001128922
LRRC32
leucine rich repeat containing 32
chr7_+_26404711 0.491 LOC441204
hypothetical locus LOC441204
chr12_-_87498225 0.489 NM_000899
NM_003994
KITLG

KIT ligand

chr1_-_184916044 0.486 NM_000963
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_27158726 0.485


chr7_+_123036312 0.469 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr9_-_71476917 0.469 NM_001163
APBA1
amyloid beta (A4) precursor protein-binding, family A, member 1
chr12_-_89922888 0.467 NM_004950
EPYC
epiphycan
chr12_-_89922875 0.465 EPYC
epiphycan
chr17_+_65677255 0.462 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr4_+_114433551 0.459 ANK2
ankyrin 2, neuronal
chr9_+_124551839 0.459 NM_001004453
OR1L6
olfactory receptor, family 1, subfamily L, member 6
chr8_+_28230567 0.454 NM_006228
PNOC
prepronociceptin
chr3_+_67131416 0.452 NM_032505
KBTBD8
kelch repeat and BTB (POZ) domain containing 8
chr11_-_57728228 0.450 NM_001004459
OR1S2
olfactory receptor, family 1, subfamily S, member 2
chr2_+_114916368 0.448 NM_020868
DPP10
dipeptidyl-peptidase 10 (non-functional)
chr8_-_67253234 0.447 NM_000756
CRH
corticotropin releasing hormone
chr11_+_130745580 0.442 NM_001048209
NTM
neurotrimin
chr4_-_40212670 0.427 NM_019027
RBM47
RNA binding motif protein 47
chr11_-_83706027 0.425 DLG2
discs, large homolog 2 (Drosophila)
chr11_+_68124400 0.423 PPP6R3
protein phosphatase 6, regulatory subunit 3
chr8_+_56177567 0.423 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr6_+_33486750 0.417 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr19_+_16115454 0.416 HSH2D
hematopoietic SH2 domain containing
chr12_+_54612055 0.414 NM_201444
NM_201445
NM_201554
DGKA


diacylglycerol kinase, alpha 80kDa


chr22_+_45071301 0.409 NM_016426
GTSE1
G-2 and S-phase expressed 1
chr2_-_179623030 0.406 NM_173648
CCDC141
coiled-coil domain containing 141
chr11_+_57738792 0.405 NM_001004458
OR1S1
olfactory receptor, family 1, subfamily S, member 1
chr6_+_154373323 0.402 NM_001145279
NM_001145280
NM_001145281
OPRM1


opioid receptor, mu 1


chrX_+_145698993 0.401 NM_001144064
CXorf51
chromosome X open reading frame 51
chr15_+_29406335 0.400 NM_015995
KLF13
Kruppel-like factor 13
chrX_+_38096679 0.399 NM_000531
OTC
ornithine carbamoyltransferase
chr2_-_119322228 0.397 NM_001426
EN1
engrailed homeobox 1
chr7_+_49783774 0.394 NM_198570
VWC2
von Willebrand factor C domain containing 2
chr3_-_191322919 0.394 NM_001134418
LEPREL1
leprecan-like 1
chr8_-_144726064 0.390 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr1_-_47428190 0.390 PDZK1IP1
PDZK1 interacting protein 1
chr3_-_184756101 0.387 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_+_144260565 0.383 NM_144698
ANKRD35
ankyrin repeat domain 35
chr9_+_133154896 0.382 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr22_-_35428848 0.379 NM_006078
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr15_+_87540238 0.374 ABHD2
abhydrolase domain containing 2
chrX_-_21686079 0.373 NM_014332
SMPX
small muscle protein, X-linked
chr9_-_106407728 0.372 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr4_-_143987053 0.372 NM_001101669
NM_003866
INPP4B

inositol polyphosphate-4-phosphatase, type II, 105kDa

chr5_-_133996362 0.371 NM_001033503
NM_016103
SAR1B

SAR1 homolog B (S. cerevisiae)

chr15_-_68781662 0.371 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_172458970 0.364 NM_003705
SLC25A12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr9_+_35032222 0.362 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chrX_-_62564934 0.362 LOC92249
hypothetical LOC92249
chr3_-_131948202 0.356 NM_014602
PIK3R4
phosphoinositide-3-kinase, regulatory subunit 4
chr5_+_32824701 0.355 NM_024563
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr17_+_30498948 0.355 NM_001033576
NM_173167
UNC45B

unc-45 homolog B (C. elegans)

chr9_-_8723893 0.350 NM_001040712
NM_001171025
NM_130391
NM_130392
NM_130393
PTPRD




protein tyrosine phosphatase, receptor type, D




chr11_+_35154775 0.350 CD44
CD44 molecule (Indian blood group)
chr17_-_60439764 0.348 GNA13
guanine nucleotide binding protein (G protein), alpha 13
chr9_+_6747919 0.348 KDM4C
lysine (K)-specific demethylase 4C
chr14_+_104117100 0.347 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr11_+_125121397 0.346 NM_138294
PATE1
prostate and testis expressed 1
chr15_+_38520594 0.344 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr12_-_51494601 0.340 NM_002272
KRT4
keratin 4
chr14_-_106149623 0.340


chr17_+_3065661 0.338 NM_014565
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr11_-_10630408 0.335 NM_001098579
MRVI1
murine retrovirus integration site 1 homolog
chr11_-_123261549 0.335 NM_001013743
TMEM225
transmembrane protein 225
chr14_+_99220349 0.332 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr3_-_102714663 0.331 NM_001077203
NM_020654
SENP7

SUMO1/sentrin specific peptidase 7

chr4_+_42590038 0.331 NM_001080476
GRXCR1
glutaredoxin, cysteine rich 1
chr3_-_187124290 0.331 TRA2B
transformer 2 beta homolog (Drosophila)
chr4_-_68766392 0.330 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr17_-_36409632 0.329 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr1_-_143708467 0.322 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr3_-_182189999 0.322 NM_001190233
NM_145261
DNAJC19

DnaJ (Hsp40) homolog, subfamily C, member 19

chr2_-_225519974 0.321 DOCK10
dedicator of cytokinesis 10
chr14_-_105900687 0.321 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2
chr20_+_31900019 0.321 CHMP4B
chromatin modifying protein 4B
chr20_-_9767406 0.320 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr11_+_103412517 0.319 NM_001001711
DDI1
DNA-damage inducible 1 homolog 1 (S. cerevisiae)
chr18_+_59571256 0.316 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr21_+_30724442 0.313 NM_181600
KRTAP13-4
keratin associated protein 13-4
chr1_-_148249152 0.312 NM_020205
OTUD7B
OTU domain containing 7B
chr14_-_106352471 0.311


chr8_-_6407882 0.310 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr2_+_220145197 0.309 NM_002191
INHA
inhibin, alpha
chr9_+_2612099 0.309 VLDLR
very low density lipoprotein receptor
chr9_+_2612134 0.308 VLDLR
very low density lipoprotein receptor
chr2_+_211129567 0.308 NM_001875
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr1_-_214963279 0.307 NM_001438
ESRRG
estrogen-related receptor gamma
chr1_-_47428310 0.307 NM_005764
PDZK1IP1
PDZK1 interacting protein 1
chr20_-_3013335 0.306 NM_000490
AVP
arginine vasopressin
chr5_-_41107161 0.305 NM_173489
HEATR7B2
HEAT repeat family member 7B2
chr10_+_127575097 0.305 NM_145235
FANK1
fibronectin type III and ankyrin repeat domains 1
chr15_-_72445551 0.305 NM_001099773
CYP11A1
cytochrome P450, family 11, subfamily A, polypeptide 1
chr8_-_11891168 0.304 NM_001033019
DEFB134
defensin, beta 134
chr1_+_22252385 0.304 CDC42
cell division cycle 42 (GTP binding protein, 25kDa)
chr3_-_69381995 0.303 FRMD4B
FERM domain containing 4B
chr12_-_73889777 0.302 NM_139136
NM_139137
NM_153748
KCNC2


potassium voltage-gated channel, Shaw-related subfamily, member 2


chr1_+_226462363 0.302 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr22_+_23945611 0.302 NM_000496
CRYBB2
crystallin, beta B2
chr4_+_113958652 0.301 NM_001127493
ANK2
ankyrin 2, neuronal
chrX_+_77267477 0.300 PGK1
phosphoglycerate kinase 1
chr22_-_34343249 0.300 NM_005368
NM_203378
MB

myoglobin

chr11_+_34599163 0.299 NM_012153
EHF
ets homologous factor
chr12_+_98565663 0.299 NM_153364
FAM71C
family with sequence similarity 71, member C
chr7_-_84654106 0.298 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chrX_+_109548940 0.297 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr2_+_33514896 0.297 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_69120188 0.296 C3orf64
chromosome 3 open reading frame 64
chr9_-_116151099 0.295 AKNA
AT-hook transcription factor
chr9_+_2612052 0.292 VLDLR
very low density lipoprotein receptor
chr10_-_97406554 0.291 NM_001017423
NM_002860
ALDH18A1

aldehyde dehydrogenase 18 family, member A1

chr14_-_20969706 0.291 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr12_-_85756766 0.291 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr19_-_54557450 0.290 NM_003598
TEAD2
TEA domain family member 2
chrX_-_79951838 0.289 NM_153252
BRWD3
bromodomain and WD repeat domain containing 3
chr6_-_46155937 0.289 NM_001114086
CLIC5
chloride intracellular channel 5
chr10_+_115300579 0.288 NM_001177660
HABP2
hyaluronan binding protein 2
chrX_-_145703940 0.287 NM_001144064
CXorf51
chromosome X open reading frame 51
chrX_-_37964924 0.286 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr3_+_46423682 0.286 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr10_+_6284845 0.285 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr5_-_36337756 0.285 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr8_+_38363150 0.284 NM_144652
LETM2
leucine zipper-EF-hand containing transmembrane protein 2
chr1_-_49014993 0.281 NM_024603
BEND5
BEN domain containing 5
chr18_+_52469559 0.280 NM_015285
NM_052834
WDR7

WD repeat domain 7

chr4_+_183482130 0.278 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chr2_+_88148413 0.277 NM_198274
SMYD1
SET and MYND domain containing 1
chr20_-_5243014 0.276 NM_144773
PROKR2
prokineticin receptor 2
chrX_-_53466273 0.275 SMC1A
structural maintenance of chromosomes 1A
chr4_+_151722526 0.273 NM_006439
MAB21L2
mab-21-like 2 (C. elegans)
chr22_-_29290875 0.271 NM_004861
GAL3ST1
galactose-3-O-sulfotransferase 1
chr1_+_938709 0.271 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr11_-_118693021 0.269 NM_006500
MCAM
melanoma cell adhesion molecule
chr4_+_46728051 0.269 NM_000812
GABRB1
gamma-aminobutyric acid (GABA) A receptor, beta 1
chr11_+_2279812 0.268 NM_139022
TSPAN32
tetraspanin 32
chr4_-_100359353 0.268 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chrX_+_79164397 0.266 NM_016954
TBX22
T-box 22
chr1_+_101475149 0.266 S1PR1
sphingosine-1-phosphate receptor 1
chr11_+_34599227 0.265 EHF
ets homologous factor
chrX_-_53466335 0.263 NM_006306
SMC1A
structural maintenance of chromosomes 1A
chr13_+_113577228 0.263 NM_001143946
GAS6
growth arrest-specific 6
chr13_-_35327798 0.262 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chrX_-_49008115 0.262 NM_001114377
NM_014009
FOXP3

forkhead box P3

chr8_-_144583718 0.261 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr22_+_42726423 0.260 NM_001003828
PARVB
parvin, beta
chr17_+_17339059 0.260


chr4_+_42094612 0.259 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)
chr4_+_91375204 0.258 NM_207491
FAM190A
family with sequence similarity 190, member A
chr8_+_67201684 0.257 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chrX_+_129133234 0.256 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chr11_-_76058542 0.256 NM_005512
LRRC32
leucine rich repeat containing 32
chr6_-_134680888 0.256 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr19_-_46626474 0.254 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr1_+_101474892 0.254 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr19_+_53664386 0.253 CYTH2
cytohesin 2
chr17_-_31219943 0.252 NM_152781
C17orf66
chromosome 17 open reading frame 66

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.51 2.24e-06 GO:0003008 system process
1.20 1.04e-04 GO:0050896 response to stimulus
1.21 5.38e-04 GO:0032501 multicellular organismal process
1.44 5.51e-03 GO:0050877 neurological system process
1.24 9.92e-03 GO:0023052 signaling
1.88 3.03e-02 GO:0015672 monovalent inorganic cation transport
1.27 3.10e-02 GO:0048731 system development
1.24 3.52e-02 GO:0007165 signal transduction

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.26 1.02e-05 GO:0005886 plasma membrane
1.25 2.24e-05 GO:0071944 cell periphery
1.28 1.73e-02 GO:0044459 plasma membrane part
1.99 2.12e-02 GO:0034702 ion channel complex
1.91 3.39e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.40 5.25e-03 GO:0005516 calmodulin binding