Motif ID: IKZF2.p2

Z-value: 2.341


Transcription factors associated with IKZF2.p2:

Gene SymbolEntrez IDGene Name
IKZF2 22807 IKAROS family zinc finger 2 (Helios)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
IKZF2chr2_-_2137232980.836.7e-05Click!


Activity profile for motif IKZF2.p2.

activity profile for motif IKZF2.p2


Sorted Z-values histogram for motif IKZF2.p2

Sorted Z-values for motif IKZF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_32698892 2.912 NM_001159996
 NRG1
neuregulin 1
chr4_-_153523113 2.630 NM_001013415
 FBXW7
F-box and WD repeat domain containing 7
chr11_+_101488380 2.619 NM_001195045
 YAP1
Yes-associated protein 1
chr3_+_99465777 2.590 NM_001005479
 OR5H6
olfactory receptor, family 5, subfamily H, member 6
chr6_+_127940011 2.455 NM_001010905
 C6orf58
chromosome 6 open reading frame 58
chr14_-_105862080 2.444 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chr14_-_106064887 2.266 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr14_+_38719462 2.240 PNN
pinin, desmosome associated protein
chr7_+_93388951 2.183 NM_004126
 GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr1_+_150852910 2.100 NM_178433
 LCE3B
late cornified envelope 3B
chr2_+_228386800 2.005 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr6_-_109795925 1.967 CD164
CD164 molecule, sialomucin
chr14_+_38720085 1.957 PNN
pinin, desmosome associated protein
chr6_+_153113624 1.953 NM_003381
NM_194435
 VIP

vasoactive intestinal peptide

chr7_+_17304707 1.902 NM_001621
 AHR
aryl hydrocarbon receptor
chr14_+_31615959 1.846 ARHGAP5
Rho GTPase activating protein 5
chr2_-_215967442 1.838 FN1
fibronectin 1
chr9_-_106401514 1.832 NM_001004482
 OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr14_+_64001969 1.826 NM_004857
 AKAP5
A kinase (PRKA) anchor protein 5
chr4_+_95595419 1.756 PDLIM5
PDZ and LIM domain 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.66 5.95e-28 GO:0007608 sensory perception of smell
2.57 1.60e-28 GO:0007606 sensory perception of chemical stimulus
1.85 8.02e-16 GO:0007600 sensory perception
1.58 7.04e-13 GO:0050877 neurological system process
1.46 2.32e-10 GO:0003008 system process
1.15 2.35e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.17 5.06e-04 GO:0071944 cell periphery
1.17 5.94e-04 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.73 2.35e-29 GO:0004984 olfactory receptor activity
1.84 1.32e-16 GO:0004930 G-protein coupled receptor activity
1.53 1.92e-10 GO:0004888 transmembrane receptor activity
1.40 4.44e-08 GO:0004872 receptor activity
1.32 3.43e-06 GO:0004871 signal transducer activity
1.32 3.43e-06 GO:0060089 molecular transducer activity