Motif ID: TFEB.p2

Z-value: 1.616


Transcription factors associated with TFEB.p2:

Gene SymbolEntrez IDGene Name
TFEB 7942 transcription factor EB

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFEBchr6_-_41810712-0.351.8e-01Click!


Activity profile for motif TFEB.p2.

activity profile for motif TFEB.p2


Sorted Z-values histogram for motif TFEB.p2

Sorted Z-values for motif TFEB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFEB.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_9126742 5.538 NM_001083625
NM_015208
 ANKRD12

ankyrin repeat domain 12

chr6_+_87921980 5.032 NM_015021
 ZNF292
zinc finger protein 292
chr4_+_128870968 3.907 NM_031291
 SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr3_-_20202622 3.429 NM_001012409
NM_001012410
NM_001012411
NM_001012412
NM_001012413
NM_138484
 SGOL1





shugoshin-like 1 (S. pombe)





chr11_+_120399966 3.092 NM_001130047
NM_152715
 TBCEL

tubulin folding cofactor E-like

chr2_+_46779553 3.005 NM_014011
 SOCS5
suppressor of cytokine signaling 5
chr19_+_37528340 2.880 NM_001136156
NM_014910
 ZNF507

zinc finger protein 507

chr6_+_127629677 2.788 NM_030963
 RNF146
ring finger protein 146
chr5_+_41940216 2.422 NM_175921
 C5orf51
chromosome 5 open reading frame 51
chr1_-_152459667 2.417 C1orf43
chromosome 1 open reading frame 43
chr11_+_18300689 2.378 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr6_-_84994032 2.321 NM_014895
 KIAA1009
KIAA1009
chr1_-_39097904 2.234 NM_022157
 RRAGC
Ras-related GTP binding C
chr1_-_152459506 2.204 C1orf43
chromosome 1 open reading frame 43
chr4_+_164484540 2.132 NM_006174
 NPY5R
neuropeptide Y receptor Y5
chr7_+_154720547 2.129 INSIG1
insulin induced gene 1
chr20_+_37024383 2.124 NM_001190809
NM_021931
 DHX35

DEAH (Asp-Glu-Ala-His) box polypeptide 35

chr1_+_152459918 2.083 NM_014847
 UBAP2L
ubiquitin associated protein 2-like
chr3_-_172109119 2.066 NM_020390
 EIF5A2
eukaryotic translation initiation factor 5A2
chr3_-_172109075 2.048 EIF5A2
eukaryotic translation initiation factor 5A2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
7.43 1.82e-04 GO:0015682 ferric iron transport
7.43 1.82e-04 GO:0033572 transferrin transport
6.08 1.85e-02 GO:0015988 energy coupled proton transport, against electrochemical gradient
6.08 1.85e-02 GO:0015991 ATP hydrolysis coupled proton transport
5.07 5.17e-03 GO:0007033 vacuole organization
4.65 2.35e-03 GO:0006818 hydrogen transport
4.47 9.18e-03 GO:0015992 proton transport
3.10 1.30e-02 GO:0008286 insulin receptor signaling pathway
2.25 1.86e-02 GO:0071495 cellular response to endogenous stimulus
2.17 9.36e-03 GO:0006886 intracellular protein transport
2.06 3.43e-03 GO:0034613 cellular protein localization
2.05 4.10e-03 GO:0070727 cellular macromolecule localization
1.91 1.48e-04 GO:0015031 protein transport
1.90 1.43e-04 GO:0045184 establishment of protein localization
1.82 7.55e-05 GO:0008104 protein localization
1.76 2.17e-02 GO:0046907 intracellular transport
1.74 4.60e-05 GO:0033036 macromolecule localization
1.56 4.32e-02 GO:0051641 cellular localization
1.35 4.18e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 41 entries
enrichment   p-value GO term description
11.26 1.06e-02 GO:0033180 proton-transporting V-type ATPase, V1 domain
10.14 3.32e-06 GO:0033176 proton-transporting V-type ATPase complex
10.14 2.04e-02 GO:0016471 vacuolar proton-transporting V-type ATPase complex
4.71 1.22e-02 GO:0016469 proton-transporting two-sector ATPase complex
4.43 7.60e-04 GO:0031902 late endosome membrane
4.10 9.76e-05 GO:0042470 melanosome
4.10 9.76e-05 GO:0048770 pigment granule
3.47 3.74e-04 GO:0005770 late endosome
3.38 2.92e-05 GO:0005774 vacuolar membrane
3.38 5.27e-05 GO:0005769 early endosome
3.36 1.85e-05 GO:0044437 vacuolar part
3.35 8.42e-12 GO:0005773 vacuole
3.10 6.42e-08 GO:0000323 lytic vacuole
3.10 6.42e-08 GO:0005764 lysosome
2.70 7.37e-05 GO:0010008 endosome membrane
2.68 8.90e-05 GO:0044440 endosomal part
2.31 1.50e-05 GO:0005768 endosome
1.72 7.14e-03 GO:0031410 cytoplasmic vesicle
1.71 1.56e-02 GO:0016023 cytoplasmic membrane-bounded vesicle
1.70 1.01e-02 GO:0031982 vesicle

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
7.88 6.62e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
5.41 3.65e-02 GO:0019829 cation-transporting ATPase activity
2.79 1.76e-04 GO:0003713 transcription coactivator activity
1.99 3.27e-02 GO:0003712 transcription cofactor activity
1.99 3.46e-02 GO:0000988 protein binding transcription factor activity
1.99 3.46e-02 GO:0000989 transcription factor binding transcription factor activity
1.19 2.28e-03 GO:0005515 protein binding
1.11 2.02e-03 GO:0005488 binding